Τρίτη 17 Σεπτεμβρίου 2019


Definition of analytical quality specifications for serum total folate measurements using a simulation outcome-based model
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Clinical Chemistry and Laboratory Medicine (CCLM)
Mon Sep 16, 2019 23:35
Procedures for the diagnosis of macro-follicle stimulating hormone (FSH) in a patient with high serum FSH concentrations
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Clinical Chemistry and Laboratory Medicine (CCLM)
Mon Sep 16, 2019 23:35
A root cause analysis of ‘falsely elevated’ oxygen saturation: investigation of pneumatic tube transport and differences between estimated and measured saturation in a critical patient population
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Clinical Chemistry and Laboratory Medicine (CCLM)
Mon Sep 16, 2019 23:35
Serum or plasma? An old question looking for new answers
Journal Name: Clinical Chemistry and Laboratory Medicine (CCLM)Issue: Ahead of print
Clinical Chemistry and Laboratory Medicine (CCLM)
Mon Sep 16, 2019 23:35
Optic nerve sheath diameter appraisal in children affected by diabetic ketoacidosis
Journal Name: Journal of Pediatric Endocrinology and MetabolismIssue: Ahead of print
Journal of Pediatric Endocrinology and Metabolism.
Mon Sep 16, 2019 23:44
Smart Phyjamas for Monitoring Physiological Signals at Night
Researchers from University of Massachusetts at Amherst have developed a new smart pajama, dubbed Phyjama, that can track physiological signals during sleep. Their work demonstrates that the technology can reliably measure heart rate, breathing rate, and sleep position during the course of the night. One day, advances like this can be incorporated into regular sleepwear, which can be an additional source of biomedical data and may help track and monitor various health conditions. ...
Medgadget
Mon Sep 16, 2019 16:39
Flexible Vitals Sensors Made from Graphene Sensitized with Quantum Dots
At the ICFO – The Institute of Photonic Sciences, in Catalonia, Spain, researchers have come up with a way to use graphene to make flexible photodetectors to measure heart rate, blood oxygen concentration, and breathing rate. Additionally, the technology can also be used to measure UV levels coming from the Sun and to communicate the measured data from the sensor to a device such as a smartphone. Today’s wearable pulse oximeters and heart rate monitors can be pretty bulky, as is the case with...
Medgadget
Mon Sep 16, 2019 19:03
Light Powered Robot Made from Hydrogel to Operate Inside Body
Engineers at University of California, Los Angeles have come up with a tiny new robot that can be controlled and powered using a beam of light. Called OsciBot, because of its oscillating motion, the robot is made entirely out of a light-responsive hydrogel and doesn’t carry its own power source, relying on an external constant light source to help it push itself along. The technology has significant medical implications, as it allows for very small, soft robots to operate within the body as a drug...
Medgadget
Mon Sep 16, 2019 19:26
Siemens Healthineers Unveils Two New Radiotherapy Planning CT Scanners
Siemens Healthineers unveiled two new CT scanners specifically designed for radiation therapy planning. The SOMATOM go.Sim and SOMATOM go.Open Pro are 64-slice and 128-slice devices, respectively, and feature an 85 cm opening suitable for larger patients. To make patient prep easier and faster, the scanners come with an optional DirectLasers system mounted on top of the gantry that projects laser light beams onto the patients. These help to align each patient accurately and are controlled...
Medgadget
Mon Sep 16, 2019 23:58
The Role of BRAF V600E in Reducing AUS/FLUS Diagnosis in Thyroid Fine Needle Aspiration
Abstract BRAF V600E mutations are common in papillary thyroid carcinoma (PTC) and some de-differentiated thyroid cancers. In this study, we summarize AUS/FLUS diagnosed cases from thyroid fine needle aspirations in our center from 2015 to 2017 to explore the impact of BRAF V600E detection on the cytopathological diagnosis of PTC. BRAF V600E detection could significantly reduce the AUS/FLUS diagnosis rates from 11.59 to 8.42% when all BRAF V600E-mutated AUS/FLUS cases were diagnosed...
Endocrine Pathology
Mon Sep 16, 2019 03:00
Risk Factors for Postoperative Complications after Sentinel Lymph Node Biopsy for Cutaneous Melanoma – Results from a Large Cohort Study
A sentinel lymph node biopsy is a common surgical procedure for cutaneous melanoma. Our aim was to evaluate risk factors for early postoperatively complications after SLN biopsy, and to examine the impact of complications on healthcare resource utilization.
Plastic, Reconstructive & Aesthetic Surgery
Mon Sep 16, 2019 03:00
A Trigger Reduction Approach to Treatment of Paradoxical Vocal Fold Motion Disorder in the Pediatric Population
Paradoxical vocal fold motion disorder (PVFMD), or induced laryngeal obstruction (ILO), is a clinical phenomenon characterized by inappropriate adduction of the true vocal folds during inspiration. The resultant episodes of acute respiratory distress marked by exercise-induced cough, inspiratory stridor, throat tightness, and shortness of breath are often misattributed to asthma despite normal pulmonary function testing results. Although the pathogenesis of the disease remains unclear, the etiology...
Journal of Voice
Mon Sep 16, 2019 03:00
Caffeine and the Dyskinesia Related to Mutations in the ADCY5 Gene
Annals of Internal Medicine Current Issue
00:51
Screening for Breast Cancer in Average-Risk Women
Annals of Internal Medicine Current Issue
00:51
Rate of Opioid Prescriptions for Patients With Acute Ankle Sprain
Annals of Internal Medicine Current Issue
00:51
Reciprocal Tears
This meeting was the beginning of a long-standing friendship during which I followed her in my personal clinic, without housestaff.
Annals of Internal Medicine Current Issue
00:51
Candida auris : An Emerging Antimicrobial Resistance Threat
Candida auris is an emerging, multidrug-resistant yeast that is now known to have caused invasive infections in more than 30 countries spanning every inhabited continent. It is an urgent antimicrobial resistance threat because many strains are resistant to at least 2 of 3 major classes of antifungal drugs and because it causes outbreaks in health care settings to an extent not seen with other Candida species.
Annals of Internal Medicine Current Issue
00:51
Witness
Annals of Internal Medicine Current Issue
00:51
General and Abdominal Adiposity and Mortality in Mexico City A Prospective Study of 150 000 Adults
Background:Some reports suggest that body mass index (BMI) is not strongly associated with mortality in Hispanic populations.Objective:To assess the causal relevance of adiposity to mortality in Mexican adults, avoiding reverse causality biases.Design:Prospective study.Setting:2 Mexico City districts.Participants:159 755 adults aged 35 years and older at recruitment, followed for up to 14 years. Participants with a hemoglobin A1c level of 7% or greater, diabetes, or other chronic diseases were excluded.Measurements:BMI,...
Annals of Internal Medicine Current Issue
00:51
Death, Taxes, and Global Warming
Annals of Internal Medicine Current Issue
00:51
Rethinking Opioid Dose Tapering, Prescription Opioid Dependence, and Indications for Buprenorphine
The expanded use of opioids for chronic pain has created a population of patients prescribed long-term opioid therapy at doses that are often above those recommended by the Centers for Disease Control and Prevention. Many patients may benefit from tapering to lower, safer doses. This commentary argues that successful tapering requires implementing and incentivizing tapering protocols, recognizing prescription opioid dependence as a distinct clinical condition necessitating treatment, and expanding...
Annals of Internal Medicine Current Issue
00:51
Sodium–Glucose Cotransporter-2 Inhibitors: Lack of a Complete History Delays Diagnosis
On 15 May 2015, the U.S. Food and Drug Administration (FDA) warned that administration of sodium–glucose cotransporter-2 (SGLT2) inhibitors could lead to ketoacidosis in patients with diabetes mellitus. This announcement came more than 2 years after the FDA's first approval of an SGLT2 inhibitor, although the phenomenon had been known for more than 125 years. Luminaries of diabetes research (including Josef von Mering, Frederick Allen, I. Arthur Mirsky, and George Cahill) had described ketosis and...
Annals of Internal Medicine Current Issue
00:51
Answering the Clinical Research Challenge in a Growing Health System
A sharp decline in clinical trials has occurred, whether measured as number of trials performed, number of participants enrolled, or number of investigators. This commentary discusses factors contributing to an environment that does not promote clinical trial research and offers suggestions for actions that academic health centers can take to counter these pressures.
Annals of Internal Medicine Current Issue
00:51
Of What Remains
Is it better or worse to know that something remains of our past once dementia robs us of our present?
Annals of Internal Medicine Current Issue
00:51
Annals Graphic Medicine - Alzheimer's Has a Funny Side Too
Annals of Internal Medicine Current Issue
00:51
Amnesia, Adverse Effects, and the Angel of History
In this issue, Leslie and colleagues compiled a disturbing tale of historical amnesia in which the neglect of 19th- and 20th-century information led to preventable adverse events in 21st-century patients. The editorialist discusses what paths we might take in drug development to ensure that we avoid repeated rediscovery of past harms.
Annals of Internal Medicine Current Issue
00:51
Would You Refer This Patient With Cancer to a Palliative Care Specialist?
Annals of Internal Medicine Current Issue
00:51
Annals Consult Guys - Peripheral Artery Disease Management
Annals of Internal Medicine Current Issue
00:51
Checklist for Initial Triage After an Anthrax Mass Exposure Event
Annals of Internal Medicine Current Issue
00:51
Annals Graphic Medicine - Progress Notes: How Is Residency?
Annals of Internal Medicine Current Issue
00:51
Screening for Breast Cancer in Average-Risk Women
Annals of Internal Medicine Current Issue
00:51
Annals for Hospitalists Inpatient Notes - Rethinking Oxygen Therapy for Hospitalized Patients
Annals of Internal Medicine Current Issue
00:51
Screening for Breast Cancer in Average-Risk Women
Annals of Internal Medicine Current Issue
00:51
Annals On Call - Community-Acquired Pneumonia: Diagnosis, Risk Stratification, and Treatment
Annals of Internal Medicine Current Issue
00:51
Annals for Educators - 17 September 2019
Annals of Internal Medicine Current Issue
00:51
Guideline: EULAR provided recommendations for thrombotic and obstetric antiphospholipid syndrome
Annals of Internal Medicine Current Issue
00:51
High-Dose Spironolactone When Patients With Acute Decompensated Heart Failure Are Resistant to Loop Diuretics: A Pilot Study
Annals of Internal Medicine Current Issue
00:51
In patients ≥ 50 years with type 2 diabetes and CV disease or risk factors, dulaglutide reduced CV outcomes
Annals of Internal Medicine Current Issue
00:51
Midlife Smaller and Larger Infarctions, White Matter Hyperintensities, and 20-Year Cognitive Decline A Cohort Study
Background:Smaller (<3-mm) infarctions are associated with stroke and stroke mortality, but relationships with cognitive decline are unknown.Objective:To characterize the relationships of smaller, larger, and both smaller and larger infarctions in middle age with 20-year cognitive decline.Design:Longitudinal cohort study.Setting:Two ARIC (Atherosclerosis Risk in Communities) study sites with magnetic resonance imaging data (1993 to 1995) and up to 5 cognitive assessments over 20 years.Participants:Stroke-free...
Annals of Internal Medicine Current Issue
00:51

In patients ≥ 50 years with type 2 diabetes and CV disease or risk factors, oral semaglutide did not increase CV events
Annals of Internal Medicine Current Issue
00:51
Menopausal Estrogen-Alone Therapy and Health Outcomes in Women With and Without Bilateral Oophorectomy
Annals of Internal Medicine Current Issue
00:51
In poorly controlled type 2 diabetes, oral semaglutide was noninferior to liraglutide for reducing HbA 1c
Annals of Internal Medicine Current Issue
00:51
Checklist for Initial Triage After an Anthrax Mass Exposure Event
Annals of Internal Medicine Current Issue
00:51
In high-risk type 1 diabetes, insulin pumps with suspend-before-low technology reduced hypoglycemic events
Annals of Internal Medicine Current Issue
00:51
Screening for Breast Cancer in Average-Risk Women
Annals of Internal Medicine Current Issue
00:51
In type 2 diabetes, intensive glucose control for 5.6 years did not differ from usual care for major CV events at 14 years
Annals of Internal Medicine Current Issue
00:51
Radiotherapy and Small Cell Carcinoma With Paraneoplastic Polyneuropathy: A Case Report
Annals of Internal Medicine Current Issue
00:51
After stroke due to ICH while on antithrombotics, starting vs avoiding antiplatelets did not differ for symptomatic ICH
Annals of Internal Medicine Current Issue
00:51
Menopausal Estrogen-Alone Therapy and Health Outcomes in Women With and Without Bilateral Oophorectomy A Randomized Trial
Background:Whether health outcomes of menopausal estrogen therapy differ between women with and without bilateral salpingo-oophorectomy (BSO) is unknown.Objective:To examine estrogen therapy outcomes by BSO status, with additional stratification by 10-year age groups.Design:Subgroup analyses of the randomized Women's Health Initiative Estrogen-Alone Trial. (ClinicalTrials.gov: NCT00000611)Setting:40 U.S. clinical centers.Participants:9939 women aged 50 to 79 years with prior hysterectomy and known...
Annals of Internal Medicine Current Issue
00:51
In treatment-resistant depression, adding esketamine nasal spray to an oral antidepressant improved symptoms at 28 days
Annals of Internal Medicine Current Issue
00:51
Checklist for Initial Triage After an Anthrax Mass Exposure Event
Annals of Internal Medicine Current Issue
00:51
The T2Bacteria Panel had 90% sensitivity for detecting targeted organisms, 43% for any bloodstream infection organism
Annals of Internal Medicine Current Issue
00:51
Diabetes Technology: Review of the 2019 American Diabetes Association Standards of Medical Care in Diabetes
Description:The American Diabetes Association (ADA) annually updates its Standards of Medical Care in Diabetes to provide clinicians, patients, researchers, payers, and other interested parties with evidence-based recommendations for the diagnosis and management of patients with diabetes.Methods:The ADA Professional Practice Committee comprises physicians, adult and pediatric endocrinologists, diabetes educators, registered dietitians, epidemiologists, pharmacists, and public health experts. To develop...
Annals of Internal Medicine Current Issue
00:51
In US veterans, PPIs were linked to increased all-cause and some cause-specific mortality compared with H 2 -blockers
Annals of Internal Medicine Current Issue
00:51
Screening for Breast Cancer in Average-Risk Women
Annals of Internal Medicine Current Issue
00:51
Annals for Hospitalists - 17 September 2019
Annals of Internal Medicine Current Issue
00:51
Would You Refer This Patient With Cancer to a Palliative Care Specialist?
Annals of Internal Medicine Current Issue
00:51

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