Related ArticlesAuthor Correction: Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations. Nat Commun. 2019 Sep 04;10(1):4082 Authors: Daya M, Rafaels N, Brunetti TM, Chavan S, Levin AM, Shetty A, Gignoux CR, Boorgula MP, Wojcik G, Campbell M, Vergara C, Torgerson DG, Ortega VE, Doumatey A, Johnston HR, Acevedo N, Araujo MI, Avila PC, Belbin G, Bleecker E, Bustamante C, Caraballo L, Cruz A, Dunston...
Fri Sep 06, 2019 18:05
Related ArticlesA gelatin hydrogel to study endometrial angiogenesis and trophoblast invasion. Interface Focus. 2019 Oct 06;9(5):20190016 Authors: Zambuto SG, Clancy KBH, Harley BAC Abstract The endometrium is the lining of the uterus and site of blastocyst implantation. Each menstrual cycle, the endometrium cycles through rapid phases of growth, remodelling and breakdown. Significant vascular remodelling is also driven by trophoblast cells that form...
Fri Sep 06, 2019 18:05
Crosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases.
Related ArticlesCrosstalk between microRNAs, the putative target genes and the lncRNA network in metabolic diseases. Mol Med Rep. 2019 Aug 21;: Authors: Assmann TS, Milagro FI, Martínez JA Abstract MicroRNAs (miRNAs/miRs) are small non‑coding RNAs (ncRNAs) that regulate gene expression. Emerging knowledge has suggested that miRNAs have a role in the pathogenesis of metabolic disorders, supporting the hypothesis that miRNAs may represent potential biomarkers...
Fri Sep 06, 2019 18:05
Related ArticlesN-Benzyl-(2,5-dioxopyrrolidin-1-yl)propanamide (AS-1) with Hybrid Structure as a Candidate for a Broad-Spectrum Antiepileptic Drug. Neurotherapeutics. 2019 Sep 04;: Authors: Kamiński K, Socała K, Zagaja M, Andres-Mach M, Abram M, Jakubiec M, Pieróg M, Nieoczym D, Rapacz A, Gawel K, Esguerra CV, Latacz G, Lubelska A, Szulczyk B, Szewczyk A, Łuszczki JJ, Wlaź P Abstract In our recent studies, we identified compound N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide...
Fri Sep 06, 2019 18:05
Related ArticlesMetalloproteinase 14 (MMP-14) and hsa-miR-410-3p expression in human inflamed dental pulp and odontoblasts. Histochem Cell Biol. 2019 Sep 05;: Authors: Brodzikowska A, Gondek A, Rak B, Paskal W, Pełka K, Cudnoch-Jędrzejewska A, Włodarski P Abstract The objective of this study is to evaluate MMP-14 expression in odontoblasts and in the bulk of dental pulp of teeth with pulpitis; to determine the expression of microRNA-410 (miR-410) in...
Fri Sep 06, 2019 18:05
Related ArticlesLDL receptor related protein 1 requires the I3 domain of discs-large homolog 1/DLG1 for interaction with the kinesin motor protein KIF13B. Biochim Biophys Acta Mol Cell Res. 2019 Sep 02;:118552 Authors: Mills J, Hanada T, Hase Y, Liscum L, Chishti AH Abstract KIF13B, a kinesin-3 family motor, was originally identified as GAKIN due to its biochemical interaction with human homolog of Drosophila discs-large tumor suppressor (hDLG1). Unlike...
Fri Sep 06, 2019 18:05
Related ArticlesAssociation between BDNF Polymorphism and Hypothalamic-Pituitary-Adrenal Activity in Later Adulthood. Gerontology. 2019 Sep 05;:1-7 Authors: Fiocco AJ, D'Amico D, de Beaumont L, Poirier J, Lupien S Abstract Stress exposure over the lifespan is robustly associated with accelerated cognitive decline in later life. Brain-derived neurotrophic factor (BDNF) is shown to regulate activity of the hypothalamic-pituitary-adrenal axis. The objective...
Fri Sep 06, 2019 18:05
204 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/09/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 07, 2019 13:46
204 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/09/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 07, 2019 15:44
19 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/09/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Sep 08, 2019 13:23
19 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: human physiology These pubmed results were generated on 2019/09/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Sep 08, 2019 15:21
62 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/06PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Fri Sep 06, 2019 18:47
144 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 07, 2019 13:18
144 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sat Sep 07, 2019 15:22
37 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Sep 08, 2019 14:02
37 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/08PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Sun Sep 08, 2019 15:59
Publication date: Available online 7 September 2019Source: Sleep MedicineAuthor(s): Leo Sher
Sun Sep 08, 2019 16:15
Publication date: Available online 7 September 2019Source: Sleep MedicineAuthor(s): M. Meira E Cruz, D. Gozal
Sun Sep 08, 2019 16:15
Publication date: Available online 7 September 2019Source: Clinical NeurophysiologyAuthor(s): Silvia Erika Kober, Daniela Pinter, Christian Enzinger, Anna Damulina, Heiko Duckstein, Siegrid Fuchs, Christa Neuper, Guilherme WoodAbstractObjectiveTo investigate the effects of EEG-based neurofeedback training, in which one can learn to self-regulate one’s own brain activity, on cognitive function in patients with multiple sclerosis (pwMS).MethodsFourteen pwMS performed ten neurofeedback training sessions...
Sun Sep 08, 2019 16:37
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): M. Alaoui Mansouri, P.-Y. Sacré, L. Coïc, C. De Bleye, E. Dumont, A. Bouklouze, Ph Hubert, R.D. Marini, E. ZiemonsAbstractHandheld Raman spectroscopy is actually booming. Recent devices improvements aim at addressing the usual Raman spectroscopy issues: fluorescence with shifted‐excitation Raman difference spectroscopy (SERDS), poor sensitivity with surface enhanced Raman scattering (SERS) and information only about the sample...
Sat Sep 07, 2019 15:49
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Xiaohui Yang, Guangping Wan, Shujuan Ma, Hongjun Xia, Jun Wang, Jiawei Liu, Yanna Liu, Gang Chen, Quan BaiAbstractRecently, superficially porous particles (SPPs) have been intensively studied and employed for highly efficient and fast separations. In this paper, the SiO2@SiO2 SPPs were synthesized by an improved polymerization-induced colloid aggregation (PICA) method using urea-formaldehyde polymer as the template. The agglomeration...
Sun Sep 08, 2019 17:02
Publication date: 15 January 2020Source: Talanta, Volume 207Author(s): Yilin Fu, Yingying Jing, Jing Gao, Zihao Li, Hongda Wang, Mingjun Cai, Ti TongAbstractTransmembrane glycoprotein Trop2 is related to many epithelial carcinomas. It not only plays roles in promoting fetal lung growth but also participates in tumor genesis, malignant transformation, and tumor dissemination. However, the detailed distribution of Trop2 at the molecular level remains unknown. Herein, we used direct stochastic optical...
Sun Sep 08, 2019 17:02
Wilms tumor is the most frequent pediatric renal malignancy, and its usual presentation is an abdominal mass or hematuria. Unusual presentations have also been reported, such as paraneoplastic syndromes (acquired von Willebrand disease, sudden death due to pulmonary embolism, and Cushing syndrome). These conditions can precede, occur concomitantly, or present in a later phase of tumor development. Precocious puberty, as paraneoplastic endocrine syndrome, has already been described in children with...
Sun Sep 08, 2019 16:05
The effect of the environment on fitness in natural populations is a fundamental question in evolutionary biology. However, most empirical field studies of fitness do not experimentally manipulate phenotypes or environmental conditions and rarely investigate more than a single species or population. Thus, the relative importance of the competitive environment versus intrinsic organismal performance in shaping the location, height, and fluidity of fitness peaks on the adaptive landscape remains largely...
Fri Sep 06, 2019 03:00
The contribution of phenotypic plasticity to adaptation is contentious, with contradictory empirical support for its role in evolution. Here I investigate the possibility that phenotype plasticity has contributed to adaptation to a novel resource. If phenotype plasticity contributes to adaptation, it is thought to evolve in a process termed genetic accommodation. Under this model, the initial response to the environment is widely variable due to cryptic genetic variation, which is then refined by...
Fri Sep 06, 2019 03:00
Abiotic stress is a major force of selection that organisms are constantly facing. While the evolutionary effects of various stressors have been broadly studied, it is only more recently that the relevance of interactions between evolution and underlying ecological conditions, that is, eco-evolutionary feedbacks, have been highlighted. Here, we experimentally investigated the interaction between adaptation to pH-stress, and ecological conditions, specifically demography. Using the protist species...
Fri Sep 06, 2019 03:00
An organism Tree of Life (organism ToL) is a conceptual and metaphorical tree to capture a simplified narrative of the evolutionary course and kinship among the extant organisms of today. Such tree cannot be experimentally validated, but may be reconstructed based on characteristics associated with the organisms. Since the whole genome sequence of an organism is, at present, the most comprehensive descriptor of the organism, a genome Tol can be an empirically derivable surrogate for the organism...
Fri Sep 06, 2019 03:00
BackgroundMore than 80% of all animal species remain unknown to science. Most of these species tend to live in the tropics and belong to animal taxa that combine small size with high specimen abundance and large species richness. For such clades, using morphology for species discovery is slow because large numbers of specimens must be sorted using detailed microscopic investigations. Fortunately, species discovery could be greatly accelerated if DNA sequences could be used for species-level sorting....
Sun Sep 08, 2019 03:00
Invasive species pose a major threat to biodiversity on islands. While successes have been achieved using traditional removal methods, such as toxicants aimed at rodents, these approaches have limitations and various off-target effects on island ecosystems. Gene drive technologies designed to eliminate a population provide an alternative approach, but the potential for drive-bearing individuals to escape from the target release area and impact populations elsewhere is a major concern. Here we propose...
Sun Sep 08, 2019 03:00
Environmental variation along the geographical space can shape populations by natural selection. In the context of global warming, accompanied by substantial changes in precipitation regimes, it is crucial to understand the role of environmental heterogeneity in tropical trees adaptation, given their disproportional contribution to water and carbon biogeochemical cycles. Here we investigated how heterogeneity in freshwater availability along tropical wetlands has influenced molecular variations of...
Sat Sep 07, 2019 03:00
Growth plates are narrow discs of cartilage, ultimately required for longitudinal growth of all mammals including humans. However, originally the growth plate and articular cartilage were a single anatomical entity, an epiphyseal cartilage, as appeared in early tetrapods and in mammalian development. The reason, why the growth plates evolved as spatially separate organs, remains unknown. Here, we demonstrate that the epiphyseal growth plate first appeared as an individual organ in amniotes due to...
Sun Sep 08, 2019 03:00
Common models of speciation with gene flow consider constant migration or admixture on secondary contact, but earth's recent climatic history suggests many populations have experienced cycles of isolation and contact over the last million years. How does this process impact the rate of speciation, and how much can we learn about its dynamics by analyzing the genomes of modern populations? Here we develop a simple model of speciation through Bateson-Dobzhansky-Muller incompatibilities in the face...
Sun Sep 08, 2019 03:00
Groups of animals possess phenotypes such as collective behaviour, which may determine the fitness of group members. However, the stability and robustness to perturbations of collective phenotypes in natural conditions is not established. Furthermore, whether group phenotypes are transmitted from parent to offspring groups is required for understanding how selection on group phenotypes contributes to evolution, but parent-offspring resemblance at the group level is rarely estimated. We evaluated...
Sun Sep 08, 2019 03:00
Evolutionary conflicts are pervasive in nature and have the potential to drive antagonistic coevolution of conflict-related traits. However, when such conflicts are weak or idiosyncratic, phenotypic signatures of coevolutionary arms races may be absent. Here, we ask whether variation in group-living traits among pine-sawfly species in the genus Neodiprion is consistent with a history of parent-offspring conflict. To address this question, we compile data on adult female clutch size, larval aggregation...
Sun Sep 08, 2019 03:00
Adapting organisms face a tension between specializing their phenotypes for certain ecological tasks or developing generalist strategies which permit persistence in multiple environmental conditions. Understanding when and how generalists or specialists evolve is therefore an important question in evolutionary dynamics. Here we study the evolution of bacterial range expansions by selecting Escherichia coli for faster migration through porous media containing one of four different sugars supporting...
Sun Sep 08, 2019 03:00
Alu insertion elements represent the largest family of Short Interspersed Nuclear Elements (SINEs) in the human genome. Polymorphic Alu elements are stable and conservative markers that can potentially be applied in studying human origin and relationships as they are identical by descent and known for lack of insertion in ancestral state. In this study, 10 Alu insertions of X chromosome were utilized to tabulate allele frequency distributions and compute parameters of forensic relevance in the 379...
Sun Sep 08, 2019 03:00
Mechanisms linking genotype to phenotype must simultaneously buffer organisms from developmental noise and allow for phenotypic plasticity in response to environmental cues. How mechanistic robustness and flexibility in biological systems bias evolution toward predictable outcomes remains an area of active debate. In this study, we leveraged phenotypic plasticity and parallel adaptation across independent lineages of Trinidadian guppies (Poecilia reticulata) to assess the predictability of transcriptional...
Sun Sep 08, 2019 03:00
Whether hybridization generates or erodes species diversity has long been debated, but to date most studies have been conducted at small taxonomic scales. Salamanders (order Caudata) represent a taxonomic order in which hybridization plays a prevalent ecological and evolutionary role. We employed a recently developed model of trait-dependent diversification to test the hypothesis that hybridization impacts the diversification dynamics of species that are currently hybridizing. We find strong evidence...
Sun Sep 08, 2019 03:00
Flower colour polymorphism (FCP) is frequently associated with differences in pollinator attraction. FCP maintenance is intriguing, as positive directional selection by pollinators should result in the loss of polymorphism. Autonomous selfing could confer reproductive assurance when pollen is limited, and could be a mechanism for maintaining polymorphism unless inbreeding depression is high. We study the role of selfing in maintaining FCP in Lysimachia arvensis, a species with blue and red morphs...
Sun Sep 08, 2019 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου