Related ArticlesSleep Apnea and Chronic Kidney Disease - A State of the Art Review. Chest. 2019 Sep 19;: Authors: Lin CH, Lurie RC, Lyons OD Abstract Patients with chronic kidney disease have increased morbidity and mortality, mainly due to cardiovascular disease. Compared to the general population, patients with chronic kidney disease have an increased prevalence of both obstructive and central sleep apnea, and the presence of sleep apnea in this population...
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22 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: ALCOHOL These pubmed results were generated on 2019/09/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Related ArticlesEfficacy and safety of levoketoconazole in the treatment of endogenous Cushing's syndrome (SONICS): a phase 3, multicentre, open-label, single-arm trial. Lancet Diabetes Endocrinol. 2019 Sep 18;: Authors: Fleseriu M, Pivonello R, Elenkova A, Salvatori R, Auchus RJ, Feelders RA, Geer EB, Greenman Y, Witek P, Cohen F, Biller BMK Abstract BACKGROUND: Levoketoconazole is a ketoconazole stereoisomer in development for treatment of Cushing's...
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Related ArticlesMetabolomics and physiological analyses reveal β-sitosterol as an important plant growth regulator inducing tolerance to water stress in white clover. Planta. 2019 Sep 21;: Authors: Li Z, Cheng B, Yong B, Liu T, Peng Y, Zhang X, Ma X, Huang L, Liu W, Nie G Abstract MAIN CONCLUSION: β-sitosterol influences amino acids, carbohydrates, organic acids, and other metabolite metabolism and homeostasis largely contributing to better tolerance...
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Related ArticlesDifferent Vibratory Conditions Elicit Different Structural and Biological Vocal Fold Changes in an In-Vivo Rabbit Model of Phonation. J Voice. 2019 Sep 18;: Authors: Kimball EE, Sayce L, Powell M, Gartling GJ, Brandley J, Rousseau B Abstract OBJECTIVE: Vibration of the vocal folds can disrupt the tissue and induce structural, functional, and molecular changes; the presence or absence of contact between the vocal folds during vibration...
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Related ArticlesA Rare Coexistence of Medullary Thyroid Cancer with Graves Disease: A Case Report and Systematic Review of the Literature. Am J Case Rep. 2019 Sep 22;20:1398-1401 Authors: Sapalidis K, Papanastasiou A, Michalopoulos N, Mantalovas S, Giannakidis D, Koimtzis GD, Florou M, Poulios C, Mantha N, Kesisoglou II Abstract BACKGROUND Graves disease is occasionally associated with thyroid cancer. The most common histological type of thyroid cancer...
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Abstract Persons suffering from opioid use disorder (OUD) experience long‐lasting dysphoric symptoms well into extended periods of withdrawal. This protracted withdrawal syndrome is notably characterized by heightened anxiety and hyperkatifeia. Here we investigated if an exacerbated withdrawal model of acute morphine dependence results in lasting behavioral adaptation 6 weeks into forced abstinence in C57BL/6J mice. We found that our exacerbated morphine withdrawal paradigm produced distinct alterations...
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Related ArticlesComparative analysis of sublingual immunotherapy medicines for adherence and clinical outcomes. Eur Arch Otorhinolaryngol. 2019 Sep 21;: Authors: Kim JA, Lee YM, Yi KI, Kim SD, Mun SJ, Cho KS Abstract OBJECTIVE: Sublingual immunotherapy (SLIT) has been considered as an effective and safe alternative to the subcutaneous route. However, different modalities and administration methods may lead to significant changes in their adherence and...
Mon Sep 23, 2019 14:40
Related ArticlesIs the maxillary sinus volume affected by concha bullosa, nasal septal deviation, and impacted teeth? A CBCT study. Eur Arch Otorhinolaryngol. 2019 Sep 21;: Authors: Tassoker M, Magat G, Lale B, Gulec M, Ozcan S, Orhan K Abstract PURPOSE: Various mechanisms play an important role in the growth of maxillary sinus cavities. The purpose of this study was to investigate the correlations of maxillary sinus volume (MSV) with nasal septal deviation...
Mon Sep 23, 2019 14:40
Related ArticlesAssessment of auditory working memory in normal hearing adults with tinnitus. Eur Arch Otorhinolaryngol. 2019 Sep 21;: Authors: Nagaraj MK, Bhaskar A, Prabhu P Abstract PURPOSE: Tinnitus is characterized by the perception of sound without an existing external stimulus. The presence of tinnitus might be intolerable for many and can be sufficiently troublesome in hearing, sleep, thought processing, and other functional abilities, all of...
Mon Sep 23, 2019 14:40
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Publication date: Available online 22 September 2019Source: Dental MaterialsAuthor(s): Marta Gallo, Hazem Abouelleil, Jean Marc Chenal, Jérôme Adrien, Joël Lachambre, Pierre Colon, Eric MaireAbstractObjectiveResin-based composites are widely used in dental restorations; however, their volumetric shrinkage during polymerization leads to several issues that reduce the restoration survival rates. For overcoming this problem, a deep study of shrinkage phenomena is necessary.MethodsIn this study, micro-tomography...
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Publication date: Available online 22 September 2019Source: Gait & PostureAuthor(s): Nikiforos Okkalidis, George Marinakis, Alfred Gatt, Marvin K Bugeja, Kenneth P Camilleri, Owen FalzonAbstractBackgroundKinematic gait analysis employing multi-segment foot models has been mainly conducted in laboratories by means of optical motion capture systems. This type of process requires considerable setup time and is constrained by a limited capture space. A procedure involving the use of multiple inertial...
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British Journal of Cancer, Published online: 23 September 2019; doi:10.1038/s41416-019-0590-7Correction: Tumour-infiltrating CD8+ lymphocytes and colorectal cancer recurrence by tumour and nodal stage
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Publication date: Available online 22 September 2019Source: Behavioural Brain ResearchAuthor(s): Maxine De Butte, Blake GiesekingAbstractMild cognitive impairment (MCI) is characterized by a reduction in cerebral blood flow. Permanent ligation of the common carotid arteries (2VO) in the rat mimics the chronic decrease in CBF that characterizes aMCI. The current study determined if melatonin (a pineal hormone with neuroprotective properties) can attenuate the neurobehavioral consequences of 2VO using...
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43 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/09/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
43 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMJ Open"[jour] These pubmed results were generated on 2019/09/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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353 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
353 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: medical science These pubmed results were generated on 2019/09/23PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Conditions: Head and Neck Neoplasm; Carcinoma, Squamous CellIntervention: Other: Blood and tumor samplesSponsor: UNC Lineberger Comprehensive Cancer CenterNot yet recruiting
Conditions: Gastric or Gastroesophageal Junction Adenocarcinoma; AFPInterventions: Drug: Anti-PD-1 antibody; Drug: XELOXSponsor: China Medical University, ChinaNot yet recruiting
Condition: Squamous Cell Carcinoma of Head and NeckIntervention: Behavioral: NDURESponsors: Medical University of South Carolina; National Cancer Institute (NCI)Not yet recruiting
Conditions: Solid Tumor; Triple-negative Breast Cancer; Gastric Adenocarcinoma; Head and Neck Squamous Cell Carcinoma; Cervical Carcinoma; High Grade Serous Ovarian Carcinoma; Hepatocellular Carcinoma; Undifferentiated Pleomorphic Sarcoma; LeiomyosarcomaInterventions: Drug: LY3435151; Drug: PembrolizumabSponsor: Eli Lilly and CompanyNot yet recruiting
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Transient self‐assembling systems often suffer from accumulation of chemical wastes that interfere with the formation of pristine self‐assembled products in subsequent cycles. Herein, we report the transient crystallization of a cucurbit[8]uril‐based host‐guest complex, preventing the accumulation of chemical wastes. Base‐catalyzed thermal decarboxylation of trichloroacetic acid that chemically fuels the crystallization process dissolves the crystals, and produces volatile chemical wastes that are...
Selective transport and concentration of molecules to specified regions on a substrate both enhances the potential to detect such molecules and provides a path to spatially localize such molecules prior to initiation of subsequent chemical reactions. Here, we first embed radially symmetric α‐, β‐, and γ‐cyclodextrin gradients in a hydrogel matrix. Driven by host‐guest interactions between the cyclodextrins and the target molecule, we observe these gradients can serve to direct 2D molecular transport....
Fucosylation of glycans is structurally diverse and has been associated with many biological and disease processes. Exact determination of fucoside positions by tandem mass spectrometry (MS/MS) is complicated by rearrangements in the gas‐phase leading to erroneous structural assignments. Here, we demonstrate that the combined use of ion mobility (IMS)‐MS and well‐defined synthetic glycan standards can prevent misinterpretation of MS/MS spectra and avoid incorrect structural assignments of fucosylated...
Photon upconversion (UC) from near‐infrared (NIR) light to visible light has enabled optogenetic manipulations in deep tissues. However, materials for NIR optogenetics have been limited to inorganic UC nanoparticles. Extension to organic triplet‐triplet annihilation (TTA)‐based UC systems would innovate NIR optogenetics toward the use of biocompatible materials placed at a desired position. Here, we report the first example of NIR light‐triggered optogenetics by using TTA‐UC hydrogels. To achieve...
A combination of a Cu–Zn solid solution interface on copper mesh with good zinc affinity and a polyacrylamide electrolyte additive (PAM) is developed to modify the zinc anode. As shown by H. Wang et al. in their Communication (DOI: https://doi.org/10.1002/anie.20190783010.1002/anie.201907830), the Cu–Zn solid solution formed in the initial process can regulate zinc nucleation and PAM can suppress the growth of zinc dendrites in the subsequent cycles. The prepared zinc anodes show a dendrite‐free...
The deadly nature of the puffer fish has been known to mankind since the dawn of civilization. However, the compound responsible for this fatal activity was isolated only in the early 20th century and has been widely known to the scientific community as tetrodotoxin since then. This review traces its history, isolation, structural elucidation, biology, and synthesis. The syntheses of unnatural derivatives are covered as well. Abstract This review provides a comprehensive coverage of the history,...
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Abstract To infer changes in the photophysical properties of porphyrins due to complexation with albumin, a combination of Z-scan and conventional spectroscopic techniques was employed. We measured the characteristics of excited states of meso-tetrakis(sulfonatophenyl) porphyrin bound to bovine serum albumin and observed that the binding reduces the intersystem crossing quantum yield and increases the internal conversion one. A reverse saturable absorption process was observed...
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Last week, Meru Health, a digital mental health clinic, announced the launch of a wearable to capture biofeedback, including heart rate variability (HRV), during mental health exercises. The clip-on wearable is affixed to an individual’s ear while they complete specific exercises, like breathing practices, directed by Meru’s platform. The goal is to show users a physiologically-relevant, quantifiable representation of the effect that correct, consistent use of breathing practices can achieve. ...
Researchers from North Carolina State University have developed a new nanostructured polymer that can kill many different strains of bacteria and viruses within minutes. Their work demonstrates that the unique chemical modifications on the polymer allow it to kill bacteria like E. coli, along with the “superbug” methicillin-resistant Staphylococcus aureus (MRSA), and that the polymer can be exposed to bacteria multiple times and still remain effective. This exciting development can be used...
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The AAA Leadership Fellows Program provides a unique opportunity for members early in their careers to learn about leadership within the Association. Fellows get an in-depth “behind the scenes” look at AAA’s governance system, discuss the range of opportunities for leadership service, and receive mentoring from Executive Board members on making room for AAA service along with their other professional commitments. JENNY BANHAssistant Professor, Anthropology and Asian American Studies, California...
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Publication date: Available online 23 September 2019Source: Archives of Oral BiologyAuthor(s): Zheng Chen, Yuxuan Wang, Zhihui Mai, Lin Chen, Jiaming Wei, Hongfei Lu, Dongdong Yuan, Hong AiAbstractObjectiveThe aim of this study is to investigate the effects of 17β-Estradiol (E2) at different concentrations combined with cyclical compressive stress on the proliferation and differentiation of mandibular condylar chondrocytes (MCCs).DesignMCCs, isolated from female Sprague-Dawley rats, were exposed...
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Zusammenfassung Alte Menschen klagen häufig darüber, dass sie an der Kommunikation mit gesprochener Sprache nicht mehr ausreichend teilnehmen können. Die Ursachen dafür liegen sowohl in pathophysiologischen Prozessen als auch in akustischen Parametern und der im hohen Alter häufig auftretenden kognitiven Leistungsminderung, die zusammen den individuellen Nutzen der Sprache stark begrenzen. Die Altersschwerhörigkeit setzt sich aus einer Vielzahl von pathophysiologischen und kognitiven...
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שְׁזִיף (בעבר נהג גם הניקוד שָׁזִיף) הוא עץ ממשפחת הוורדניים הנושא פרי סגלגל ועסיסי. מניין לנו שם זה? שיזף כבר בספרות חז"ל יש שם פרי שאחת ממסורות הקריאה שלו היא "שזיפים", ואולם כיום מקובל לזהות אותו עם צמח אחר ששמו המדעי Ziziphus ובעברית שֵׁיזָף (על פי מסורת קריאה אחרת בספרות חז"ל) – ממשפחת האשחריים. מקובל לקשור בין השם Ziziphus ובין השם 'שיזף', ונראה כי מקור שני השמות בלשון אחרת, ממקום מוצאו של העץ במזרח הרחוק. פירות השיזף מכונים גם בשם 'דומים' (על בסיס אחד משמותיו הערביים של העץ – דום), המוכר...
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