Related ArticlesDecitabine promotes apoptosis in mesenchymal stromal cells isolated from patients with myelodysplastic syndromes by inducing reactive oxygen species generation. Eur J Pharmacol. 2019 Sep 19;:172676 Authors: Wang L, Guo X, Guo X, Zhang X, Ren J Abstract Myelodysplastic syndromes (MDSs) are a group of clonal disorders of hematopoietic stem cells, resulting in ineffective hematopoiesis. Previous studies have reported that decitabine (DAC)...
Mon Sep 23, 2019 14:03
Related ArticlesBilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest. Phytomedicine. 2019 Aug 23;64:153073 Authors: Wang Q, Wu ZL, Yuan X, Dong HY, Xu X, Xin H, Wang YH, Zhang JB, Chen L, Li HL, Zhang XM, Zhang WD Abstract BACKGROUND: Ginkgo biloba (Gb) extracts have been used as a traditional Chinese medicine. Gb contains flavonoids, which are considered to be its active ingredients and have been...
Mon Sep 23, 2019 14:03
Related ArticlesThe melanopsin-directed white noise electroretinogram (wnERG). Vision Res. 2019 Sep 18;: Authors: Adhikari P, Zele AJ, Cao D, Kremers J, Feigl B Abstract The white noise electroretinogram (wnERG) provides a measure of the impulse response function under conditions of retinal equilibrium; it is yet to be determined how the electrical response generated by melanopsin ganglion cell photoreception is expressed in the impulse response. To...
Mon Sep 23, 2019 15:03
Related ArticlesmountainClimber Identifies Alternative Transcription Start and Polyadenylation Sites in RNA-Seq. Cell Syst. 2019 Sep 05;: Authors: Cass AA, Xiao X Abstract Alternative transcription start (ATS) and alternative polyadenylation (APA) create alternative RNA isoforms and modulate many aspects of RNA expression and protein production. However, ATS and APA remain difficult to detect in RNA sequencing (RNA-seq). Here, we developed mountainClimber,...
Mon Sep 23, 2019 15:03
Related ArticlesA robust computational framework for estimating 3D Bi-Atrial chamber wall thickness. Comput Biol Med. 2019 Sep 12;114:103444 Authors: Wang Y, Xiong Z, Nalar A, Hansen BJ, Kharche S, Seemann G, Loewe A, Fedorov VV, Zhao J Abstract Atrial fibrillation (AF) is the most prevalent form of cardiac arrhythmia. The atrial wall thickness (AWT) can potentially improve our understanding of the mechanism underlying atrial structure that drives AF...
Mon Sep 23, 2019 15:03
Complement-mediated thrombotic microangiopathy is a rare form of thrombotic microangiopathy but has high rates of mortality and morbidity. Effective treatment exists with eculizumab for this condition, but administration of treatment is often delayed because of overlapping symptoms with other causes of thrombotic microangiopathy. We present a case of a 78-year-old male who was eventually diagnosed with complement-mediated thrombotic microangiopathy. We also discuss the use of the PLASMIC scoring...
Mon Sep 23, 2019 11:05
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Mark Chiew, Karla L. MillerAbstractWe introduce an approach to reconstruction of simultaneous multi-slice (SMS)-fMRI data that improves statistical efficiency. The method incorporates regularization to adjust temporal smoothness in a spatially varying, encoding-dependent manner, reducing the g-factor noise amplification per temporal degree of freedom. This results in a net improvement in tSNR and GLM efficiency, where the efficiency...
Mon Sep 23, 2019 13:08
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Elvira Khachatryan, Benjamin Wittevrongel, Mansoureh Fahimi Hnazaee, Evelien Carrette, Ine Dauwe, Alfred Meurs, Paul Boon, Dirk van Roost, Marc M. Van HulleAbstractFacilitation of object processing in the brain due to a related context (priming) can be influenced by both semantic connections and perceptual similarity. It is thus important to discern these two when evaluating the spatio-temporal dynamics of primed object processing....
Mon Sep 23, 2019 13:08
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Jaakko O. Nieminen, Lari M. Koponen, Niko Mäkelä, Victor Hugo Souza, Matti Stenroos, Risto J. IlmoniemiAbstractShort-interval intracortical inhibition (SICI) has been studied with paired-pulse transcranial magnetic stimulation (TMS) by administering two pulses at a millisecond-scale interstimulus interval (ISI) to a single cortical target. It has, however, been difficult to study the interaction of nearby cortical targets with...
Mon Sep 23, 2019 13:08
Publication date: December 2019Source: NeuroImage, Volume 203Author(s): Jin Gu, Linjing Cao, Baolin LiuAbstractValence is a dimension of emotion and can be either positive, negative, or neutral. Valences can be expressed through the visual and auditory modalities, and the valences of each modality can be conveyed by different types of stimuli (face, body, voice or music). This study focused on the modality-general representations of valences, that is, valence information can be shared across not...
Mon Sep 23, 2019 13:08
Related ArticlesPrevalence and scope of advanced practice provider oncology care among Medicare beneficiaries with breast cancer. Breast Cancer Res Treat. 2019 Sep 21;: Authors: Yen TWF, Laud PW, McGinley EL, Pezzin LE, Nattinger AB Abstract PURPOSE: Advanced practice providers (APPs) have increasingly become members of the oncology care team. Little is known about the scope of care that APPs are performing nationally. We determined the prevalence and...
Mon Sep 23, 2019 14:03
Related ArticlesThe relationship between the findings of vestibular evoked myogenic potentials and severity of obstructive sleep apnea syndrome. Eur Arch Otorhinolaryngol. 2019 Sep 21;: Authors: Ulusoy B, Gül O, Elsürer Ç, Bozkurt MK, Tülek B, Körez MK, Ekmekçi H, Çolpan B Abstract PURPOSE: Our study aimed to evaluate the effects of chronic hypoxic state in Obstructive Sleep Apnea Syndrome (OSAS) on brainstem pathways using Vestibular Evoked Myogenic...
Mon Sep 23, 2019 16:17
Related ArticlesTranslational Genomics and Recent Advances in Oral Squamous Cell Carcinoma. Semin Cancer Biol. 2019 Sep 19;: Authors: Yeeng Chai AW, Lim KP, Cheong SC Abstract Oral squamous cell carcinomas (OSCC) are a heterogeneous group of cancers arising from the mucosal lining of the oral cavity. A majority of these cancers are associated with lifestyle risk habits including smoking, excessive alcohol consumption and betel quid chewing. Cetuximab,...
Mon Sep 23, 2019 14:15
Related ArticlesEvaluation and therapy outcome in children with auditory neuropathy spectrum disorder (ANSD). Int J Pediatr Otorhinolaryngol. 2019 Sep 13;127:109681 Authors: Ehrmann-Müller D, Cebulla M, Rak K, Scheich M, Back D, Hagen R, Shehata-Dieler W Abstract OBJECTIVES: The aims of the present study are to: describe diagnostic findings in patients with auditory neuropathy spectrum disorder (ANSD); and demonstrate the outcomes of different therapies...
Mon Sep 23, 2019 14:15
Related ArticlesDefining atypical croup: A case report and review of the literature. Int J Pediatr Otorhinolaryngol. 2019 Sep 17;127:109686 Authors: Hanna R, Lee F, Drummond D, Yunker WK Abstract BACKGROUND: Croup is a common respiratory illness in children. It presents with a barky cough, stridor and hoarseness occurring secondary to inflammation of the subglottis and larynx. The clinical course of croup is well-described, however atypical presentations...
Mon Sep 23, 2019 14:15
Related ArticlesHistogram analysis parameters derived from DCE-MRI in head and neck squamous cell cancer - Associations with microvessel density. Eur J Radiol. 2019 Sep 14;120:108669 Authors: Meyer HJ, Hamerla G, Leifels L, Höhn AK, Surov A Abstract PURPOSE: DCE MRI is a functional imaging modality, which is widely acknowledged to be linked to microvessel density in tissues. Therefore, it might be able to predict vessels in tumors. The present study...
Mon Sep 23, 2019 14:15
Related ArticlesResilience and quality of life (QoL) of head and neck cancer and brain tumour survivors in Pakistan: an analytical cross-sectional study protocol. BMJ Open. 2019 Sep 20;9(9):e029084 Authors: Zahid N, Khalid W, Ahmad K, Bhamani SS, Azam I, Asad N, Jabbar AA, Khan M, Enam A Abstract BACKGROUND: Cancer is a devastating disease and has detrimental effects on the quality of life (QoL) of cancer survivors and interferes with their treatment...
Mon Sep 23, 2019 14:15
Related ArticlesPathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron. 2019 Sep 04;: Authors: Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, Gestwicki JE, Xu K, Kosik KS, Gan L Abstract Dysregulation of neuronal excitability underlies the pathogenesis of tauopathies, including frontotemporal dementia (FTD) with tau inclusions....
Mon Sep 23, 2019 15:29
Related ArticlesThe 5-Hydroxytryptamine receptor 1F stimulates mitochondrial biogenesis and angiogenesis in endothelial cells. Biochem Pharmacol. 2019 Sep 19;:113644 Authors: Dupre TV, Jenkins DP, Muise-Helmericks RC, Schnellmann RG Abstract A hallmark of acute kidney injury (AKI) is vascular rarefication and mitochondrial dysfunction. Promoting vascular recovery following AKI could facilitate kidney repair as the vasculature is responsible for oxygen...
Mon Sep 23, 2019 15:29
Related ArticlesFeasibility and Challenges of Microsurgical Resection of Colloid Cysts in Patients with Pre-Existing Ventriculoperitoneal Shunts. World Neurosurg. 2019 Sep 19;: Authors: Majmundar N, Ward M, Liu JK Abstract INTRODUCTION: Colloid cysts are the most common third ventricular tumor and may present with symptoms related to obstructive hydrocephalus. Though definitive endoscopic or microsurgical resection is the standard of care, patients may...
Mon Sep 23, 2019 14:53
Related ArticlesResults of a single center's stenting procedure for the treatment of carotid stenosis. World Neurosurg. 2019 Sep 19;: Authors: Vieira-Leite C, Mosqueira AJ, Arias-Rivas S, Rodríguez-Yáñez M, Pumar JM PMID: 31542440 [PubMed - as supplied by publisher]
Mon Sep 23, 2019 14:53
Related ArticlesConservative management for late-presenting dural tears after spine surgery: An institutional experience and literature review. World Neurosurg. 2019 Sep 19;: Authors: Varma Kalidindi KK, Bhat MR, Mannem A, Chhabra HS Abstract BACKGROUND: Symptoms and evidence of CSF leak after an uneventful intraoperative and immediate postoperative course are a rare entity in spine surgery. The literature is sparse on the description of such Late Presenting...
Mon Sep 23, 2019 14:53
Related ArticlesRepeated deterioration of consciousness resulting from spontaneous intracranial hypotension associated with deep cerebral vein stagnation: a Case report. World Neurosurg. 2019 Sep 19;: Authors: Uchino H, Hamada S, Kashiwazaki D, Tomita T, Akioka N, Akai T, Kuroda S Abstract BACKGROUND: Although the clinical course of spontaneous intracranial hypotension (SIH) is generally benign, in unusual cases it can result in deterioration of consciousness....
Mon Sep 23, 2019 14:53
Related ArticlesEmbolization and open decompression of a giant aneurysm involving the P2 segment of the posterior cerebral artery. World Neurosurg. 2019 Sep 19;: Authors: O'Connor KP, Strickland AE, Ernst G, Milton CK, Cheema AA, Bohnstedt BN Abstract A 5-year-old girl presented to the clinic with chronic intermittent left-sided headaches. The patient underwent CT angiography which demonstrated a giant aneurysm that involved the P2 segment of the left...
Mon Sep 23, 2019 14:53
Related ArticlesThe Origins of Eponymous Aneurysm Clips: A Review. World Neurosurg. 2019 Sep 19;: Authors: Jumah F, Quinoa T, Akel O, Shah S, Narayan V, Adeeb N, Gupta G, Nanda A Abstract Aneurysm clips are indispensable tools in the armamentarium of vascular neurosurgeons. The history of aneurysm clips development is a witness of ingenuity and tenacity in treating a potentially devastating disease. Few know the stories of their innovators and the inspiration...
Mon Sep 23, 2019 14:53
Related ArticlesRadix saw: a useful tool for rhinoplasty to correct high radix. Braz J Otorhinolaryngol. 2019 Aug 07;: Authors: Şeneldir S, Dizdar D, Tuna A Abstract INTRODUCTION: The most difficult aspect of radix lowering is determining the maximum amount of bone that can be removed with osteotomes; here, we describe use of a radix saw, which is a new tool for determining this amount. OBJECTIVE: In this study, we describe use of a radix saw,...
Mon Sep 23, 2019 15:29
Related ArticlesTranslational anatomy of the left atrium and esophagus as relevant to the pulmonary vein antral isolation for atrial fibrillation. Surg Radiol Anat. 2019 Sep 21;: Authors: Gupta T, Cheema N, Randhawa A, Sahni D Abstract PURPOSE: Pulmonary vein antrum isolation by radiofrequency ablation has become a preferred treatment for atrial fibrillation. The aim of our research is to study the anatomy of the PVantrum and its related structures with...
Mon Sep 23, 2019 15:35
Related ArticlesPrognostic effect of troponin elevation in patients undergoing carotid endarterectomy with regional anesthesia - A prospective study. Int J Surg. 2019 Sep 19;: Authors: Pereira-Macedo J, Rocha-Neves JP, Dias-Neto MF, Andrade JPV Abstract BACKGROUND: Myocardial injury after noncardiac surgery (MINS) occurs in 15% of patients undergoing carotid endarterectomy (CEA) with general anesthesia. Short and long-term risk of myocardial infarction...
Mon Sep 23, 2019 14:39
Related ArticlesClosure of mesenteric defects is associated with a higher incidence of small bowel obstruction due to adhesions after laparoscopic antecolic Roux-en-y gastric bypass: a retrospective cohort study. Int J Surg. 2019 Sep 19;: Authors: Nuytens F, Van Rooy F, D'Hondt M, Vansteenkiste F, Pottel H, Abasbassi M, Servaege A, Devriendt D Abstract INTRODUCTION: Small bowel obstruction (SBO) is a frequent complication after laparoscopic Roux-en-y...
Mon Sep 23, 2019 14:39
Related ArticlesSevere anemia may not be a contraindication to debridement in a Jehovah's witness patient with necrotizng fasciitis of the lower extremity - A case report. Int J Surg Case Rep. 2019 Sep 04;63:27-30 Authors: Ogedegbe C, Fernando J, Kaul S Abstract INTRODUCTION: Necrotizing fasciitis is a severe soft tissue infection characterized by rapidly progressing necrosis involving the fascia and subcutaneous tissue. Necrotizing fasciitis of the...
Mon Sep 23, 2019 15:35
Related ArticlesCancer chemotherapy on immune recovery rate of CD4 cells in people living with HIV in Yaoundé, Cameroon. Bull Cancer. 2019 Sep 18;: Authors: Mbassa Nnouma G, Tchatchouang S, Kagoué Siméni LA, Ebogo Belobo JT, Okobalemba A PMID: 31542166 [PubMed - as supplied by publisher]
Mon Sep 23, 2019 15:40
Related Articles[Cancer of the vulva: Diagnostic stages, treatment and survival in a country with limited resources (Burkina Faso)]. Bull Cancer. 2019 Sep 18;: Authors: Zongo N, Korsaga Somé N, Ouédraogo S, Ouédraogo AS, Zamané H, Zida M, Ouangre E, Sanou A, Niampa P, Lompo OM, Traoré A, Dem A Abstract INTRODUCTION: Vulvar cancer is rare and belatedly diagnosed in Africa. We describe its diagnostic stages, therapeutic and evolution features in a country...
Mon Sep 23, 2019 15:40
Related ArticlesEpidemiologic features and risk factors of sepsis in ischemic stroke patients admitted to intensive care: A prospective cohort study. J Clin Neurosci. 2019 Sep 18;: Authors: Zaid Y, Rajeh A, Hosseini Teshnizi S, Alqarn A, Tarkesh F, Esmaeilinezhad Z, Nikandish R Abstract BACKGROUND/OBJECTIVE: Stroke is the second leading cause of death globally that predisposed to sepsis. Therefore, this study was aimed to assess the risk factors and...
Mon Sep 23, 2019 14:00
Related ArticlesThe association between disability and unintentional injuries among adolescents in a general education setting: Evidence from a Swedish population-based school survey. Disabil Health J. 2019 Sep 12;:100841 Authors: Jernbro C, Bonander C, Beckman L Abstract BACKGROUND: Unintentional injuries are the leading cause of death among adolescents. Adolescents with disabilities may be particularly vulnerable with an increased risk of unintentional...
Mon Sep 23, 2019 14:03
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