Abstract Purpose Recently, the new hybrid chelator DATA (6-amino-1,4-diazepine-triacetate) has been introduced, which has the advantage of high yield and radiolabelling of DATA-based octreotide derivative (TOC) at room temperature in contrast to tetraazacyclododecane-1,4,7,10-tetraacetate (DOTA) that needs 95 °C for effective labelling. However, the diagnostic potential of DATA-TOC has not been studied with other chelators in humans. The...
Publication date: Available online 20 November 2019Source: Revista Española de Medicina Nuclear e Imagen MolecularAuthor(s): A. Custodio Rebollo Aguirre, R. Sánchez Sánchez, A.D. González Jiménez, M. Culiañez Casas, I. Mendoza Arnau, M. Rashki, T. Rudolphi Solero, S. Martínez MecaResumenObjetivoPresentar nuestra experiencia inicial en el procedimiento combinado de detección intraoperatoria del ganglio axilar positivo biopsiado marcado con semilla de 125I (GM) y biopsia del ganglio centinela (GC)...
Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia after rewarming is proven to be detrimental in clinical trials. However, the cellular mechanisms and kinetics of post-TTM rebound pyrexia remain to be elucidated. Therefore, we investigated the effects of cooling and post-TTM pyrexia on the inflammatory...
A previous study has demonstrated that adiponectin (APN) could promote preadipocyte differentiation, and the present study further explored its mechanism. 3T3-L1 cells were infected with adenovirus holding human adiponectin gene apM1 and mouse neuronatin (Nnat) shRNA and initiated differentiation while coculturing with mature adipocytes stimulated with LPS. After 8 days, preadipocyte differentiation was observed by Oil Red O staining. Real-time quantitative PCR was used to evaluate mRNA expression...
Publication date: Available online 21 November 2019Source: Clinical ImagingAuthor(s): Qing Wang, Xin Wang, Qingqing WuAbstractObjectivesThis study aimed to evaluate the association of nuchal septations with chromosomal anomalies during the first trimester of pregnancy.MethodsA total of 281 patients who were diagnosed to have elevated nuchal translucency (NT > 3 mm) or nuchal septations during the first trimester from Jan. 2014 to Dec. 2016 were included. These patients were divided into three...
Publication date: Available online 20 November 2019Source: Medical Image AnalysisAuthor(s): Kristoffer Wickstrø m, Michael Kampffmeyer, Robert JenssenAbstractColorectal polyps are known to be potential precursors to colorectal cancer, which is one of the leading causes of cancer-related deaths on a global scale. Early detection and prevention of colorectal cancer is primarily enabled through manual screenings, where the intestines of a patient is visually examined. Such a procedure can be challenging...
Publication date: Available online 21 November 2019Source: NeuroImageAuthor(s): Yuqi Deng, Inyong Choi, Barbara Shinn-CunninghamAbstractVisual and somatosensory spatial attention both induce parietal alpha (7–14 Hz) oscillations whose topographical distribution depends on the direction of spatial attentional focus. In the auditory domain, contrasts of parietal alpha power for leftward and rightward attention reveal qualitatively similar lateralization; however, it is not clear whether alpha lateralization...
Publication date: Available online 20 November 2019Source: NeuroImageAuthor(s): D. Kumral, F. Şansal, E. Cesnaite, K. Mahjoory, E. Al, M. Gaebler, V.V. Nikulin, A. VillringerAbstractVariability of neural activity is regarded as a crucial feature of healthy brain function, and several neuroimaging approaches have been employed to assess it noninvasively. Studies on the variability of both evoked brain response and spontaneous brain signals have shown remarkable changes with aging but it is unclear...
Publication date: Available online 21 November 2019Source: Academic RadiologyAuthor(s): Jack H. Ruddell, Adam E.M. Eltorai, Oliver Y. Tang, Johanna A. Suskin, Elizabeth H. Dibble, M. Elizabeth Oates, Don C. YooBackgroundNuclear medicine (NM) is a multidisciplinary field. Its overlap with nuclear radiology (NR) creates unique training considerations, opportunities, and challenges. Various factors impact the workforce, training needs, and training pathways. This state of flux may be perplexing to prospective...
Publication date: Available online 21 November 2019Source: Academic RadiologyAuthor(s): Kun-Han Lue, Yi-Feng Wu, Shu-Hsin Liu, Tsung-Cheng Hsieh, Keh-Shih Chuang, Hsin-Hon Lin, Yu-Hung ChenRationale and ObjectivesRadiomic analysis of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) images enables the extraction of quantitative information of intratumour heterogeneity. This study investigated whether the baseline 18F-FDG PET/CT radiomics can predict treatment...
Publication date: Available online 21 November 2019Source: Academic RadiologyAuthor(s): Charles M Maxfield
Publication date: Available online 20 November 2019Source: Academic RadiologyAuthor(s): Sagar Kulkarni, Saurabh JhaTuberculosis is a leading cause of death from infectious disease worldwide, and is an epidemic in many developing nations. Countries where the disease is common also tend to have poor access to medical care, including diagnostic tests. Recent advancements in artificial intelligence may help to bridge this gap. In this article, we review the applications of artificial intelligence in...
Abstract Purpose We aimed to evaluate if imaging biomarkers on FDG PET are associated with clinical outcomes in patients with advanced non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs). Methods In this retrospective monocentric study, we included 109 patients with advanced NSCLC who underwent baseline FDG PET/CT before ICI...
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