IJMS, Vol. 20, Pages 5723: PpAKR1A, a Novel Aldo-Keto Reductase from Physcomitrella Patens, Plays a Positive Role in Salt Stress International Journal of Molecular Sciences doi: 10.3390/ijms20225723 Authors: Lu Chen Fang Bao Shuxuan Tang Enhui Zuo Qiang Lv Dongyang Zhang Yong Hu Xiaoqin Wang Yikun He The moss Physcomitrella patens is tolerant of highly saline environments. In plants, salinity stress may induce the production of toxic reactive carbonyl species...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5718: The Hypervariable Region of K-Ras4B Governs Molecular Recognition and Function International Journal of Molecular Sciences doi: 10.3390/ijms20225718 Authors: Abdelkarim Banerjee Grudzien Leschinsky Abushaer Gaponenko The flexible C-terminal hypervariable region distinguishes K-Ras4B, an important proto-oncogenic GTPase, from other Ras GTPases. This unique lysine-rich portion of the protein harbors sites for post-translational modification,...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5719: Hsp40 Protein DNAJB6 Interacts with Viral NS3 and Inhibits the Replication of the Japanese Encephalitis Virus International Journal of Molecular Sciences doi: 10.3390/ijms20225719 Authors: Yu-Qin Cao Lei Yuan Qin Zhao Jian-Lin Yuan Chang Miao Yung-Fu Chang Xin-Tian Wen Rui Wu Xiao-Bo Huang Yi-Ping Wen Qi-Gui Yan Yong Huang Xin-Feng Han Xiao-Ping Ma San-Jie Cao The Japanese encephalitis virus (JEV) is a mosquito-borne...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5716: Celastrol Induces Necroptosis and Ameliorates Inflammation via Targeting Biglycan in Human Gastric Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms20225716 Authors: Dandan Guo Wei Zhang Haijie Yang Jiajia Bi Yunfei Xie Binfeng Cheng Yan Wang Sujuan Chen Celastrol, a triterpene isolated from the root of traditional Chinese medicine Thunder of God Vine, possesses anti-cancer and anti-inflammatory activity to treat rheumatoid...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5717: Blood Testis Barrier and Somatic Cells Impairment in a Series of 35 Adult Klinefelter Syndrome Patients International Journal of Molecular Sciences doi: 10.3390/ijms20225717 Authors: Giudice Vermeulen Wyns Klinefelter Syndrome (KS) is the most common genetic cause of infertility in men. Degeneration of the testicular tissue starts in utero and accelerates at puberty with hyalinisation of seminiferous tubules, spermatogonia apoptosis and germ cell maturation...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5714: HBx and c-MYC Cooperate to Induce URI1 Expression in HBV-Related Hepatocellular Carcinoma International Journal of Molecular Sciences doi: 10.3390/ijms20225714 Authors: Tsuchiya Amisaki Takenaga Honjo Fujiwara Shiota Unconventional prefoldin RNA polymerase II subunit 5 interactor (URI1) has emerged as an oncogenic driver in hepatocellular carcinoma (HCC). Although the hepatitis B virus (HBV) represents the most common etiology of HCC worldwide,...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5715: Special Issue: The Actin-Myosin Interaction in Muscle: Background and Overview International Journal of Molecular Sciences doi: 10.3390/ijms20225715 Authors: John Squire Muscular contraction is a fundamental phenomenon in all animals; without it life as we know it would be impossible. The basic mechanism in muscle, including heart muscle, involves the interaction of the protein filaments myosin and actin. Motility in all cells is also partly based on similar...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5713: Antimicrobial Peptides as Anti-Infective Agents in Pre-Post-Antibiotic Era? International Journal of Molecular Sciences doi: 10.3390/ijms20225713 Authors: Tomislav Rončević Jasna Puizina Alessandro Tossi Resistance to antibiotics is one of the main current threats to human health and every year multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a result. Ever since their discovery, some 40 years ago, the antimicrobial...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5712: Characterizing the Role of TaWRKY13 in Salt Tolerance International Journal of Molecular Sciences doi: 10.3390/ijms20225712 Authors: Shuo Zhou Wei-Jun Zheng Bao-Hua Liu Jia-Cheng Zheng Fu-Shuang Dong Zhi-Fang Liu Zhi-Yu Wen Fan Yang Hai-Bo Wang Zhao-Shi Xu He Zhao Yong-Wei Liu The WRKY transcription factor superfamily is known to participate in plant growth and stress response. However, the role of this family in wheat (Triticum...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5709: GABA-Alleviated Oxidative Injury Induced by Salinity, Osmotic Stress and their Combination by Regulating Cellular and Molecular Signals in Rice International Journal of Molecular Sciences doi: 10.3390/ijms20225709 Authors: Mohamed S. Sheteiwy Hongbo Shao Weicong Qi Yousef Alhaj Hamoud Hiba Shaghaleh Nasr Ullah Khan Ruiping Yang Boping Tang This study was conducted in order to determine the effect of priming with γ-aminobutyric...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5711: Effects of Gonadotropin-Releasing Hormone (GnRH) and Its Analogues on the Physiological Behaviors and Hormone Content of Tetrahymena pyriformis International Journal of Molecular Sciences doi: 10.3390/ijms20225711 Authors: Eszter Lajkó Éva Pállinger Zsombor Kovács Ildikó Szabó László Kőhidai The unicellular Tetrahymena distinguishes structure-related vertebrate hormones by its chemosensory reactions. In the present work, the selectivity of hormone...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5710: The Biological Effects of Complete Gasoline Engine Emissions Exposure in a 3D Human Airway Model (MucilAirTM) and in Human Bronchial Epithelial Cells (BEAS-2B) International Journal of Molecular Sciences doi: 10.3390/ijms20225710 Authors: Pavel Rossner Tereza Cervena Michal Vojtisek-Lom Kristyna Vrbova Antonin Ambroz Zuzana Novakova Fatima Elzeinova Hasmik Margaryan Vit Beranek Martin Pechout David Macoun Jiri Klema Andrea Rossnerova...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5708: Fast Vibrational Modes and Slow Heterogeneous Dynamics in Polymers and Viscous Liquids International Journal of Molecular Sciences doi: 10.3390/ijms20225708 Authors: Francesco Puosi Antonio Tripodo Dino Leporini Many systems, including polymers and molecular liquids, when adequately cooled and/or compressed, solidify into a disordered solid, i.e., a glass. The transition is not abrupt, featuring progressive decrease of the microscopic mobility and huge...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5706: CRISPR/Cas9-Mediated Knock-Out of KrasG12D Mutated Pancreatic Cancer Cell Lines International Journal of Molecular Sciences doi: 10.3390/ijms20225706 Authors: Eva Lentsch Lifei Li Susanne Pfeffer Arif B. Ekici Leila Taher Christian Pilarsky Robert Grützmann In 90% of pancreatic ductal adenocarcinoma cases, genetic alteration of the proto-oncogene Kras has occurred, leading to uncontrolled proliferation of cancerous cells. Targeting Kras has...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5705: Optimization of ZnAl/Chitosan Supra-Nano Hybrid Preparation as Efficient Antibacterial Material International Journal of Molecular Sciences doi: 10.3390/ijms20225705 Authors: Bi Foua Claude Alain Gohi Hong-Yan Zeng Sheng Xu Kai-Min Zou Binyao Liu Xiu Li Huang Xiao-Ju Cao The menace of antimicrobial resistance continues to increase and hence the need to discover new antibiotics, especially alternative and effective sources such as hybrid organic-inorganic,...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5707: Epidermolysis Bullosa-Associated Squamous Cell Carcinoma: From Pathogenesis to Therapeutic Perspectives International Journal of Molecular Sciences doi: 10.3390/ijms20225707 Authors: Angelo Giuseppe Condorelli Elena Dellambra Elena Logli Giovanna Zambruno Daniele Castiglia Epidermolysis bullosa (EB) is a heterogeneous group of inherited skin disorders determined by mutations in genes encoding for structural components of the cutaneous basement membrane...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5704: Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility
IJMS, Vol. 20, Pages 5704: Circadian Gene Polymorphisms Associated with Breast Cancer Susceptibility International Journal of Molecular Sciences doi: 10.3390/ijms20225704 Authors: Monika Lesicka Ewa Jabłońska Edyta Wieczorek Beata Pepłońska Jolanta Gromadzińska Barbara Seroczyńska Leszek Kalinowski Jarosław Skokowski Edyta Reszka Breast cancer (BC) is a major problem for civilization, manifested by continuously increasing morbidity and mortality among women worldwide....
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5703: Provitamin A Biofortification of Durum Wheat through a TILLING Approach International Journal of Molecular Sciences doi: 10.3390/ijms20225703 Authors: Francesco Sestili Maria Dolores Garcia-Molina Gianluca Gambacorta Romina Beleggia Ermelinda Botticella Pasquale De Vita Daniel Valentin Savatin Stefania Masci Domenico Lafiandra Macro- and micronutrients, essential for the maintenance of human metabolism, are assimilated daily through...
Thu Nov 14, 2019 02:00
IJMS, Vol. 20, Pages 5702: rAAV Engineering for Capsid-Protein Enzyme Insertions and Mosaicism Reveals Resilience to Mutational, Structural and Thermal Perturbations International Journal of Molecular Sciences doi: 10.3390/ijms20225702 Authors: Rebecca C. Feiner Julian Teschner Kathrin E. Teschner Marco T. Radukic Tobias Baumann Sven Hagen Yvonne Hannappel Niklas Biere Dario Anselmetti Katja M. Arndt Kristian M. Müller Recombinant adeno-associated viruses...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1981: Innate Immunity and Alcohol Journal of Clinical Medicine doi: 10.3390/jcm8111981 Authors: Kany Janicova Relja The innate immunity has evolved during millions of years, and thus, equivalent or comparable components are found in most vertebrates, invertebrates, and even plants. It constitutes the first line of defense against molecules, which are either pathogen-derived or a danger signal themselves, and not seldom both. These molecular patterns are comprised...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1982: Achievements in the Topographic Design of Commercial Titanium Dental Implants: Towards Anti-Peri-Implantitis Surfaces Journal of Clinical Medicine doi: 10.3390/jcm8111982 Authors: Asensio Vázquez-Lasa Rojo Titanium and its alloys constitute the gold standard materials for oral implantology in which their performance is mainly conditioned by their osseointegration capacity in the host’s bone. We aim to provide an overview of the advances in...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1980: Heterogeneity of Vascular Endothelial Cells, De Novo Arteriogenesis and Therapeutic Implications in Pancreatic Neuroendocrine Tumors Journal of Clinical Medicine doi: 10.3390/jcm8111980 Authors: Bin Ren J. Bart Rose Yehe Liu Renata Jaskular-Sztul Carlo Contreras Adam Beck Herbert Chen Arteriogenesis supplies oxygen and nutrients in the tumor microenvironment (TME), which may play an important role in tumor growth and metastasis. Pancreatic neuroendocrine...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1979: Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro Journal of Clinical Medicine doi: 10.3390/jcm8111979 Authors: Mélanie VELIER Stéphanie SIMONCINI Maxime ABELLAN Pauline FRANCOIS Sandy EAP Anaïs LAGRANGE Baptiste BERTRAND Aurélie DAUMAS Brigitte GRANEL Bruno DELORME Françoise DIGNAT GEORGE Jérémy MAGALON Florence SABATIER Innovative therapies based...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1976: Artificial Intelligence-Based Thyroid Nodule Classification Using Information from Spatial and Frequency Domains Journal of Clinical Medicine doi: 10.3390/jcm8111976 Authors: Dat Tien Nguyen Tuyen Danh Pham Ganbayar Batchuluun Hyo Sik Yoon Kang Ryoung Park Image-based computer-aided diagnosis (CAD) systems have been developed to assist doctors in the diagnosis of thyroid cancer using ultrasound thyroid images. However, the performance of these systems...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1977: The Effects of Helmet Therapy Relative to the Size of the Anterior Fontanelle in Nonsynostotic Plagiocephaly: A Retrospective Study Journal of Clinical Medicine doi: 10.3390/jcm8111977 Authors: Do Gon Kim Joon Seok Lee Jeong Woo Lee Jung Dug Yang Ho Yun Chung Byung Chae Cho Kang Young Choi Helmet therapy is an important nonsurgical approach for patients with nonsynostotic plagiocephaly, but its effectiveness may depend on certain anatomical...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1975: A Computational Approach for the Assessment of Executive Functions in Patients with Obsessive–Compulsive Disorder Journal of Clinical Medicine doi: 10.3390/jcm8111975 Authors: Elisa Pedroli Filippo La Paglia Pietro Cipresso Caterina La Cascia Giuseppe Riva Daniele La Barbera Previous studies on obsessive–compulsive disorder (OCD) showed impairments in executive domains, particularly in cognitive inhibition. In this perspective, the use...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1973: Microbiota Dysbiosis in Fungal Rhinosinusitis Journal of Clinical Medicine doi: 10.3390/jcm8111973 Authors: Yen-Ting Lu Shao-Hung Wang Ming-Li Liou Ting-An Shen Ying-Chou Lu Chung-Han Hsin Shun-Fa Yang Yih-Yuan Chen Tzu-Hao Chang Fungal rhinosinusitis is a unique phenotype of chronic rhinosinusitis with unique clinical and histological characteristics. The role of bacterial microbiota in various phenotypes chronic rhinosinusitis is not...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1978: Cell-Free Osteochondral Scaffold for the Treatment of Focal Articular Cartilage Defects in Early Knee OA: 5 Years’ Follow-Up Results Journal of Clinical Medicine doi: 10.3390/jcm8111978 Authors: Andrea Sessa Luca Andriolo Alessandro Di Martino Iacopo Romandini Roberto De Filippis Stefano Zaffagnini Giuseppe Filardo The purpose of this study was to investigate the clinical results at five years’ follow-up of a tri-layered nanostructured...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1972: Coping Strategies in Male Patients under Treatment for Substance Use Disorders and/or Severe Mental Illness: Influence in Clinical Course at One-Year Follow-Up Journal of Clinical Medicine doi: 10.3390/jcm8111972 Authors: Julia E. Marquez-Arrico Laura Río-Martínez José Francisco Navarro Gemma Prat Diego A. Forero Ana Adan Coping strategies have an impact on substance use disorders (SUD), relapses, and clinical variables, but knowledge on this area...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1969: Fractures of the Humeral Shaft with Primary Radial Nerve Palsy: Do Injury Mechanism, Fracture Type, or Treatment Influence Nerve Recovery? Journal of Clinical Medicine doi: 10.3390/jcm8111969 Authors: Roman C. Ostermann Nikolaus W. Lang Julian Joestl Leo Pauzenberger Thomas M. Tiefenboeck Patrick Platzer Adult humeral shaft fractures are associated with primary radial nerve palsy in up to 18% of cases. The purpose of this study was to assess the...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1974: Impact of Pregnancy on Intra-Host Genetic Diversity of Influenza A Viruses in Hospitalised Women: A Retrospective Cohort Study Journal of Clinical Medicine doi: 10.3390/jcm8111974 Authors: Gregory Destras Maxime Pichon Bruno Simon Martine Valette Vanessa Escuret Pierre-Adrien Bolze Gil Dubernard Pascal Gaucherand Bruno Lina Laurence Josset Characterising dynamics of Influenza A Viruses (IAV) within-host evolution is an active field...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1967: Lung Microbiome in Asthma: Current Perspectives Journal of Clinical Medicine doi: 10.3390/jcm8111967 Authors: Konstantinos Loverdos Georgios Bellos Louiza Kokolatou Ioannis Vasileiadis Evangelos Giamarellos Matteo Pecchiari Nikolaos Koulouris Antonia Koutsoukou Nikoletta Rovina A growing body of evidence implicates the human microbiome as a potentially influential player actively engaged in shaping the pathogenetic processes underlying...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1970: History of Inflammatory Bowel Diseases Journal of Clinical Medicine doi: 10.3390/jcm8111970 Authors: Giovanni Clemente Actis Rinaldo Pellicano Sharmila Fagoonee Davide Giuseppe Ribaldone Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1966: Connectome Analysis of Brain Functional Network Alterations in Depressive Patients with Suicidal Attempt Journal of Clinical Medicine doi: 10.3390/jcm8111966 Authors: Jun-Cheng Weng Yu-Syuan Chou Yuan-Hsiung Tsai Chun-Te Lee Ming-Hong Hsieh Vincent Chin-Hung Chen Our study aimed to clarify the neuroimaging correlates of suicide attempt by comparing differences in functional magnetic resonance imaging (fMRI) among depressed suicide attempters, depressed...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1968: Clinical Relevance of Immunobiology in Umbilical Cord Blood Transplantation
JCM, Vol. 8, Pages 1968: Clinical Relevance of Immunobiology in Umbilical Cord Blood Transplantation Journal of Clinical Medicine doi: 10.3390/jcm8111968 Authors: Hyun Don Yun Ankur Varma Mohammad J. Hussain Sunita Nathan Claudio Brunstein Umbilical cord blood transplantation (UCBT) has been an important donor source for allogeneic hematopoietic stem cell transplantation, especially for patients who lack suitable matched donors. UCBT provides unique practical advantages,...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1971: Primary Immune Thrombocytopenia: A Translational Research Model for Autoimmune Diseases Journal of Clinical Medicine doi: 10.3390/jcm8111971 Authors: Emmanuel Andrès Primary immune thrombocytopenia (ITP), formally known as idiopathic thrombocytopenic purpura, is a multifactorial autoimmune disease that is both idiopathic (cause unknown) and rare [...]
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1965: Interaction of the p.Q141K Variant of the ABCG2 Gene with Clinical Data and Cytokine Levels in Primary Hyperuricemia and Gout Journal of Clinical Medicine doi: 10.3390/jcm8111965 Authors: Veronika Horváthová Jana Bohatá Markéta Pavlíková Kateřina Pavelcová Karel Pavelka Ladislav Šenolt Blanka Stibůrková Gout is an inflammatory arthritis influenced by environmental risk factors and genetic variants. The common dysfunctional p.Q141K allele of...
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1964: Beware Weakening the Ivory Tower of MDT Diagnosis in Interstitial Lung Disease Journal of Clinical Medicine doi: 10.3390/jcm8111964 Authors: Nazia Chaudhuri Colm Leonard Accurate diagnosis of interstitial lung disease (ILD) has always been the cornerstone of ensuring appropriate treatment planning and prognostic discussions with patients [...]
Thu Nov 14, 2019 02:00
JCM, Vol. 8, Pages 1963: Etiology of Minor Troponin Elevations in Patients with Atrial Fibrillation at Emergency Department–Tropo-AF Study Journal of Clinical Medicine doi: 10.3390/jcm8111963 Authors: Samuli Jaakkola Tuomas Paana Ilpo Nuotio Tuomas O. Kiviniemi Jussi-Pekka Pouru Pekka Porela Fausto Biancari K. E. Juhani Airaksinen Patients with atrial fibrillation (AF) presenting to the emergency department (ED) often have elevated cardiac troponin T (TnT) levels...
Thu Nov 14, 2019 02:00
JFB, Vol. 10, Pages 50: In Situ Crosslinking Bionanocomposite Hydrogels with Potential for Wound Healing Applications Journal of Functional Biomaterials doi: 10.3390/jfb10040050 Authors: Federica Leone Melike Firlak Kirsty Challen Wayne Bonnefin Barbara Onida Karen L. Wright John G. Hardy In situ forming hydrogels are a class of biomaterials that can fulfil a variety of important biomedically relevant functions and hold promise for the emerging field of patient-specific...
Thu Nov 14, 2019 02:00
JoF, Vol. 5, Pages 107: Deletion of the SKO1 Gene in a hog1 Mutant Reverts Virulence in Candida albicans Journal of Fungi doi: 10.3390/jof5040107 Authors: Verónica Urrialde Daniel Prieto Susana Hidalgo-Vico Elvira Román Jesús Pla Rebeca Alonso-Monge Candida albicans displays the ability to adapt to a wide variety of environmental conditions, triggering signaling pathways and transcriptional regulation. Sko1 is a transcription factor that was previously involved in early...
02:00
JoF, Vol. 5, Pages 106: Updates on the Taxonomy of Mucorales with an Emphasis on Clinically Important Taxa Journal of Fungi doi: 10.3390/jof5040106 Authors: Walther Wagner Kurzai Fungi of the order Mucorales colonize all kinds of wet, organic materials and represent a permanent part of the human environment. They are economically important as fermenting agents of soybean products and producers of enzymes, but also as plant parasites and spoilage organisms. Several taxa cause...
Thu Nov 14, 2019 02:00
Life, Vol. 9, Pages 85: Membrane Lipid Composition and Amino Acid Excretion Patterns of Methanothermococcus okinawensis Grown in the Presence of Inhibitors Detected in the Enceladian Plume Life doi: 10.3390/life9040085 Authors: Ruth-Sophie Taubner Lydia M. F. Baumann Thorsten Bauersachs Elisabeth L. Clifford Barbara Mähnert Barbara Reischl Richard Seifert Jörn Peckmann Simon K.-M. R. Rittmann Daniel Birgel Lipids and amino acids are regarded as important biomarkers...
Thu Nov 14, 2019 02:00
Life, Vol. 9, Pages 84: Prebiotic Chemistry that Could Not Not Have Happened Life doi: 10.3390/life9040084 Authors: Steven A. Benner Hyo-Joong Kim Elisa Biondi We present a direct route by which RNA might have emerged in the Hadean from a fayalite–magnetite mantle, volcanic SO2 gas, and well-accepted processes that must have created substantial amounts of HCHO and catalytic amounts of glycolaldehyde in the Hadean atmosphere. In chemistry that could not not have happened,...
Thu Nov 14, 2019 02:00
Medicina, Vol. 55, Pages 739: The Financial Burden of Setting up a Pediatric Robotic Surgery Program
Medicina, Vol. 55, Pages 739: The Financial Burden of Setting up a Pediatric Robotic Surgery Program Medicina doi: 10.3390/medicina55110739 Authors: Boia David Background and Objectives: Robotic surgery is currently at the forefront of both adult and pediatric treatment. The main limit in the wide adoption of this technology is the high cost of purchasing and running the robotic system. This report will focus on the costs assessment of running a robotic program in a pediatric surgery...
Thu Nov 14, 2019 02:00
Medicina, Vol. 55, Pages 738: Translation, Cultural, and Clinical Validation of the Lithuanian Version of the Spiritual Needs Questionnaire among Hospitalized Cancer Patients Medicina doi: 10.3390/medicina55110738 Authors: Riklikienė Spirgienė Kaselienė Luneckaitė Tomkevičiūtė Büssing Background and Objectives: The aim was to translate and validate the spiritual needs questionnaire for its use in the Lithuanian context. Materials and Methods: A descriptive, cross-sectional...
Thu Nov 14, 2019 02:00
Medicina, Vol. 55, Pages 737: Transition-Age Young Adults with Cerebral Palsy: Level of Participation and the Influencing Factors Medicina doi: 10.3390/medicina55110737 Authors: Rožkalne Mukāns Vētra Background and Objectives: The aim of this study was to identify the level of participation in the context of the developmental transition from adolescence to adult life for young adults with cerebral palsy (CP) and the factors that had an influence on participation. Materials...
Thu Nov 14, 2019 02:00
Medicina, Vol. 55, Pages 736: Steroids and L-Lysine Aescinate for Acute Radiculopathy Due to a Herniated Lumbar Disk Medicina doi: 10.3390/medicina55110736 Authors: Mykhaylo Oros Mykhailo Oros Jar Vasyl Grabar Background and objectives. The efficacy of commonly prescribed analgesic and adjuvant drugs for the management of patients with radiculopathy has not been well established. Oral steroids are commonly used to treat sciatica or radiculopathy due to a herniated disk but the...
Thu Nov 14, 2019 02:00
Metabolites, Vol. 9, Pages 280: Effects of Aging and Methionine Restriction on Rat Kidney Metabolome
Metabolites, Vol. 9, Pages 280: Effects of Aging and Methionine Restriction on Rat Kidney Metabolome Metabolites doi: 10.3390/metabo9110280 Authors: Irene Pradas Mariona Jové Rosanna Cabré Victoria Ayala Natalia Mota-Martorell Reinald Pamplona Methionine restriction (MetR) in animal models extends maximum longevity and seems to promote renoprotection by attenuating kidney injury. MetR has also been proven to affect several metabolic pathways including lipid metabolism....
Thu Nov 14, 2019 02:00
Microorganisms, Vol. 7, Pages 564: The Effects of Colicin Production Rates on Allelopathic Interactions in Escherichia coli PopulationsMicroorganisms doi: 10.3390/microorganisms7110564Authors: Ghazaryan Giladi GillorAllelopathic interactions mediated by bacteriocins production serve microorganisms in the never-ending battle for resources and living space. Competition between the bacteriocin producer and sensitive populations results in the exclusion of one or the other depending on their initial...
Thu Nov 14, 2019 02:00
Microorganisms, Vol. 7, Pages 565: Mapping Epitopes of a Novel Peptidoglycan Cross-Linking Enzyme Cwp22 Recognized by Human Sera Obtained from Patients with Clostridioides difficile Infection and Cord BloodMicroorganisms doi: 10.3390/microorganisms7110565Authors: Razim Pacyga Martirosian Szuba Gamian Myc GórskaClostridioides difficile (CD) cause a severe diarrhea which can lead to pseudomembranous colitis and even patient death. CD infection (CDI) is connected mainly with changes in intestinal microbiota...
Thu Nov 14, 2019 02:00
Microorganisms, Vol. 7, Pages 563: Meta-Analysis and Meta-Regression Indicate Dynamic Prevalence and Moderators of Foodborne Pathogens in African Indigenous Fermented MilkMicroorganisms doi: 10.3390/microorganisms7110563Authors:Joseph WambuiPatrick Murigu Kamau NjageTaurai TasaraElna Maria BuysAs more microbiological data for indigenous fermented milk (IFM) becomes available, concern about their microbial safety becomes eminent. Nonetheless, these data are highly fragmented, and a tool is required...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4130: Palladium(II)-Catalyzed Efficient Synthesis of Wedelolactone and Evaluation as Potential Tyrosinase Inhibitor Molecules doi: 10.3390/molecules24224130 Authors: Huidan Huang Jianqiu Chen Jie Ren Chaofeng Zhang Fei Ji Tyrosinase is an enzyme widely distributed in nature, which has multiple functions, especially in the melanin biosynthesis pathway. Despite the few clinically available tyrosinase inhibitors for whitening, a great demand remains...
02:00
Molecules, Vol. 24, Pages 4128: The Composition of Fatty Acids in Ostrich Meat Influenced by the Type of Packaging and Refrigerated Storage Molecules doi: 10.3390/molecules24224128 Authors: Olaf K. Horbańczuk Małgorzata Moczkowska Joanna Marchewka Atanas G. Atanasov Marcin A. Kurek Ostrich meat is a high-quality dietetic product, however, it is very sensitive to deterioration during storage. The aim of this study was to assess the effect of packaging systems on the fatty...
02:00
Molecules, Vol. 24, Pages 4125: A Comprehensive Review on Infrared Heating Applications in Food Processing Molecules doi: 10.3390/molecules24224125 Authors: Salam A. Aboud Ammar B. Altemimi Asaad R. S. Al-HiIphy Lee Yi-Chen Francesco Cacciola Infrared (IR) technology is highly energy-efficient, less water-consuming, and environmentally friendly compared to conventional heating. Further, it is also characterized by homogeneity of heating, high heat transfer rate, low heating...
02:00
Molecules, Vol. 24, Pages 4127: Levels of Trace Elements in the Aqueous Humor of Cataract Patients Measured by the Inductively Coupled Plasma Optical Emission Spectrometry Molecules doi: 10.3390/molecules24224127 Authors: Dolar-Szczasny Święch Flieger Tatarczak-Michalewska Niedzielski Proch Majerek Kawka Mackiewicz Trace elements play an important role in the pathogenesis of several serious ophthalmological disorders, such as glaucoma, age-related macular...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4126: In Situ SABRE Hyperpolarization with Earth’s Field NMR Detection Molecules doi: 10.3390/molecules24224126 Authors: Hill-Casey Sakho Mohammed Rossetto Ahwal Duckett John Richardson Virgo Halse Hyperpolarization methods, which increase the sensitivity of nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI), have the potential to expand the range of applications of these powerful analytical techniques...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4124: Discrimination of the Geographical Origin of the Lateral Roots of Aconitum carmichaelii Using the Fingerprint, Multicomponent Quantification, and Chemometric Methods Molecules doi: 10.3390/molecules24224124 Authors: Lu-Lin Miao Qin-Mei Zhou Cheng Peng Chun-Wang Meng Xiao-Ya Wang Liang Xiong Fuzi is a well-known traditional Chinese medicine developed from the lateral roots of Aconitum carmichaelii Debx. It is rich in alkaloids that display...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4123: Development of Bioepoxy Resin Microencapsulated Ammonium-Polyphosphate for Flame Retardancy of Polylactic Acid Molecules doi: 10.3390/molecules24224123 Authors: Kata Decsov Katalin Bocz Beáta Szolnoki Serge Bourbigot Gaëlle Fontaine Dániel Vadas György Marosi Ammonium-polyphosphate (APP) was modified by microencapsulation with a bio-based sorbitol polyglycidyl ether (SPE)-type epoxy resin and used as a flame retardant additive in polylactic...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4121: Microbial Conversion of Toxic Resin Acids Molecules doi: 10.3390/molecules24224121 Authors: Natalia A. Luchnikova Kseniya M. Ivanova Ekaterina V. Tarasova Victoria V. Grishko Irina B. Ivshina Organic wood extractives—resin acids—significantly contribute to an increase in the toxicity level of pulp and paper industry effluents. Entering open ecosystems, resin acids accumulate and have toxic effects on living organisms, which...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4118: Bio-Guided Fractionation of Prenylated Benzaldehyde Derivatives as Potent Antimicrobial and Antibiofilm from Ammi majus L. Fruits-Associated Aspergillus amstelodami Molecules doi: 10.3390/molecules24224118 Authors: Noha Fathallah Marwa M. Raafat Marwa Y. Issa Marwa M. Abdel-Aziz Mokhtar Bishr Mostafa A. Abdelkawy Osama Salama Ammi majus L.; Family Apiaceae; is a plant indigenous to Egypt. Its fruits contain bioactive compounds such as...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4120: Synthesis and Biological Evaluation of Genistein-IR783 Conjugate: Cancer Cell Targeted Delivery in MCF-7 for Superior Anti-Cancer Therapy Molecules doi: 10.3390/molecules24224120 Authors: Yang Guan Yi Zhang Juan Zou Li-Ping Huang Mahendra D. Chordia Wei Yue Jin-Jun Wu Dong-Feng Pan The flavonoid-based natural product genistein is a biologically active compound possessing promising anti-oxidant and anti-cancer properties. Poor pharmacokinetics...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4119: A Nucleoside/Nucleobase-Rich Extract from Cordyceps Sinensis Inhibits the Epithelial–Mesenchymal Transition and Protects against Renal Fibrosis in Diabetic Nephropathy Molecules doi: 10.3390/molecules24224119 Authors: Zhonghua Dong Yueyue Sun Guangwei Wei Siying Li Zhongxi Zhao Cordyceps Sinensis, a traditional Chinese medicine and a healthy food, has been used for the treatment of kidney disease for a long time. The aim of present study was...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4114: Interfacial Behavior of Oligo(Ethylene Glycol) Dendrons Spread Alone and in Combination with a Phospholipid as Langmuir Monolayers at the Air/Water Interface Molecules doi: 10.3390/molecules24224114 Authors: Da Shi Dinh-Vu Nguyen Mounir Maaloum Jean-Louis Gallani Delphine Felder-Flesch Marie Pierre Krafft Dendrons consisting of two phosphonate functions and three oligo(ethylene glycol) (OEG) chains grafted on a central phenoxyethylcarbamoylphenoxy...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4117: Coordination Ring-Opening Polymerization of Cyclic Esters: A Critical Overview of DFT Modeling and Visualization of the Reaction Mechanisms Molecules doi: 10.3390/molecules24224117 Authors: Ilya Nifant’ev Pavel Ivchenko Ring-opening polymerization (ROP) of cyclic esters (lactones, lactides, cyclic carbonates and phosphates) is an effective tool to synthesize biocompatible and biodegradable polymers. Metal complexes effectively catalyze ROP, a remarkable...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4116: Identification of The Fipronil Resistance Associated Mutations in Nilaparvata lugens GABA Receptors by Molecular Modeling Molecules doi: 10.3390/molecules24224116 Authors: Yafeng Tian Ya Gao Yanming Chen Genyan Liu Xiulian Ju Fipronil, as the first commercialized member of phenylpyrazole insecticides, has been widely used to control planthoppers in China due to its high insecticidal activity and low toxicity to mammals. However, insects have...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4122: Planar Chiral [2.2]Paracyclophane-Based Bisoxazoline Ligands and Their Applications in Cu-Mediated N–H Insertion Reaction Molecules doi: 10.3390/molecules24224122 Authors: Daniel M. Knoll Yuling Hu Zahid Hassan Martin Nieger Stefan Bräse New catalysts for important C–N bond formation are highly sought after. In this work, we demonstrate the synthesis and viability of a new class of planar chiral [2.2]paracyclophane-based bisoxazoline...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4112: Anti-Amyloidogenic and Cyclooxygenase Inhibitory Activity of Guettarda speciosa Molecules doi: 10.3390/molecules24224112 Authors: Mario A. Tan Mark Wilson D. Lagamayo Grecebio Jonathan D. Alejandro Seong Soo A. An Guettarda speciosa is known in traditional folk medicine for treating cough, cold, sore throat, fever, wounds, epilepsy, and headaches. To discover the scientific pharmacological potential of G. speciosa, we explore its anti-inflammatory,...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4113: Reflectometry Reveals Accumulation of Surfactant Impurities at Bare Oil/Water Interfaces Molecules doi: 10.3390/molecules24224113 Authors: Ernesto Scoppola Samantha Micciulla Lucas Kuhrts Armando Maestro Richard A. Campbell Oleg V. Konovalov Giovanna Fragneto Emanuel Schneck Bare interfaces between water and hydrophobic media like air or oil are of fundamental scientific interest and of great relevance for numerous applications. A...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4115: 5,8-Quinolinedione Scaffold as a Promising Moiety of Bioactive Agents Molecules doi: 10.3390/molecules24224115 Authors: Monika Kadela-Tomanek Ewa Bębenek Elwira Chrobak Stanisław Boryczka Natural 5,8-quinolinedione antibiotics exhibit a broad spectrum of activities including anticancer, antibacterial, antifungal, and antimalarial activities. The structure–activity research showed that the 5,8-quinolinedione scaffold is responsible for...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4111: Exposure of Human Gastric Cells to Oxidized Lipids Stimulates Pathways of Amino Acid Biosynthesis on a Genomic and Metabolomic Level Molecules doi: 10.3390/molecules24224111 Authors: Mathias Zaunschirm Marc Pignitter Antonio Kopic Claudia Keßler Christina Hochkogler Nicole Kretschy Mark Manuel Somoza Veronika Somoza The Western diet is characterized by a high consumption of heat-treated fats and oils. During deep-frying processes,...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4110: Synthesis of Resins Using Epoxies and Humins as Building Blocks: A Mechanistic Study Based on In-Situ FT-IR and NMR Spectroscopies Molecules doi: 10.3390/molecules24224110 Authors: Xavier Montané Roxana Dinu Alice Mija The combination of eco-respectful epoxy compounds with the humins, a by-product of biomass chemical conversion technologies, allow the obtention of materials with high added value. In this work, we propose a chemical connection study...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4109: Phenolic Profile, Antioxidant Activity, and Anti-obesogenic Bioactivity of Mao Luang Fruits (Antidesma bunius L.) Molecules doi: 10.3390/molecules24224109 Authors: Ornnicha Krongyut Khaetthareeya Sutthanut To investigate the anti-obesity potential of Antidesma bunius L. (MM), a Thai local fruit which is named “Mao Luang,” we have focused on the effects on pancreatic α-amylase and lipase enzyme activity and on adipocyte...
Thu Nov 14, 2019 02:00
Molecules, Vol. 24, Pages 4108: Concentration of Mercury in the Livers of Small Terrestrial Rodents from Rural Areas in Poland Molecules doi: 10.3390/molecules24224108 Authors: Maciej Durkalec Agnieszka Nawrocka Jacek Żmudzki Aleksandra Filipek Marcin Niemcewicz Andrzej Posyniak Small terrestrial mammals could be used as accumulative biomonitors of different environmental contaminants, but the knowledge of the level of Hg in their bodies is scant. The aim of our research...
Thu Nov 14, 2019 02:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου