Related ArticlesNEN: Advancement in Diagnosis and Minimally Invasive Therapy. Rofo. 2019 Nov 20;: Authors: Putzer D, Schullian P, Jaschke W, Bale R Abstract Neuroendocrine neoplasms (NEN) are a heterogeneous type of malignant disease and frequently present with symptoms caused by the secretion of metabolically active substances or the manifestation of distant metastases, with the liver being the most frequent site of spreading. Early diagnosis of metastatic...
Related ArticlesCerebellar glioblastoma in an NF1 patient. Is it surgical debulking really necessary? Br J Neurosurg. 2019 Nov 20;:1-3 Authors: Flower H, Gallo P Abstract Introduction: Neurofibromatosis type 1 is an autosomal dominant tumour syndrome with an increased risk of developing central nervous system neoplasms, mostly benign low-grade gliomas involving the optic pathway and the brainstem. High-grade astrocytomas or glioblastoma multiforme (GBM)...
Related ArticlesTreatment and survival of primary intracranial germ cell tumors: a population-based study using SEER database. J Cancer Res Clin Oncol. 2019 Nov 19;: Authors: Denyer S, Bhimani AD, Patil SN, Mudreac A, Behbahani M, Mehta AI Abstract INTRODUCTION: Primary intracranial germ cell tumors are rare neoplasms derived from gonadal cells. They are categorized as germinoma, non-germinomatous germ cell tumor (NGCCT), or teratoma, with the latter...
Related ArticlesGiant Cell-rich Tanycytic Ependymoma as Intramedullary Spinal Mass. Neurol India. 2019 Sep-Oct;67(5):1327-1330 Authors: Parkhi M, Gupta K, Singh A, Salunke P Abstract Intramedullary spinal cord tumors are rare neoplasms and harbour full spectrum of primary neoplasms as seen within the intracranial compartment. They include tumors with diverse pathologies, arising in both adults and children and pose considerable diagnostic challenge....
Related ArticlesIdentification of hypermutation and defective mismatch repair in ctDNA from metastatic prostate cancer. Clin Cancer Res. 2019 Nov 19;: Authors: Ritch E, Fu SYF, Herberts C, Wang G, Warner EW, Schönlau E, Taavitsainen S, Murtha AJ, Vandekerkhove G, Beja K, Loktionova Y, Khalaf D, Fazli L, Kushnir I, Ferrario C, Hotte S, Annala M, Chi KN, Wyatt AW Abstract PURPOSE: DNA mismatch repair defects (MMRd) and tumor hypermutation are rare and...
Related ArticlesA tricky and rare cause of pulmonary eosinophilia: myeloid/lymphoid neoplasm with eosinophilia and rearrangement of PDGFRA. BMC Pulm Med. 2019 Nov 19;19(1):216 Authors: Zanelli M, Smith M, Zizzo M, Carloni A, Valli R, De Marco L, Foroni M, Palicelli A, Martino G, Ascani S Abstract BACKGROUND: Eosinophilic lung diseases represent a heterogeneous group of disorders with prominent infiltrate of eosinophils in lung interstitium and alveolar...
Related ArticlesPhlegmonous gastritis in a patient with mixed-phenotype acute leukemia in the neutropenia phase during chemotherapy: A case report. Medicine (Baltimore). 2019 Nov;98(45):e17777 Authors: Shi D, He J, Lv M, Liu R, Zhao T, Jiang Q Abstract RATIONALE: Phlegmonous gastritis is a rare bacterial infection of the gastric wall with high mortality. However, diagnosis of phlegmonous gastritis is difficult and standard treatment remains unestablished....
Related ArticlesRadiation therapy in mycosis fungoid patient. Pan Afr Med J. 2019;33:227 Authors: Chellakhi M, Khalfaoui I, Benchakroun N, Bouchbika Z, Jouhadi H, Tawfiq N, Sahraoui S, Benider A, Chellakhi N, Quessar A Abstract Mycosis fungoid (MF) is a non-Hodgkin's T-cell lymphoma determined by primary cutaneous involvement. It is a slow-progressing chronic indolent disease characterized by atypical T-cells with a cerebral nucleus. Management of...
Related ArticlesPrimary jejunal melanoma as a cause of adult intussusception: a case report and review of literature. Pan Afr Med J. 2019;33:214 Authors: Olatoke SA, Agodirin SO, Adenuga AT, Lawal BO, Ibrahim KO, Folaranmi OO Abstract Primary melanoma of the small bowel is a rare clinical entity with a paucity of published reports in literature. Most cases of gastrointestinal melanomas are metastatic lesions arising from skin or ocular origins. This...
Related ArticlesGastrointestinal hemorrhage caused by small intestinal benign tumors: 2 cases report. Pan Afr Med J. 2019;33:197 Authors: Kane M, Benaboud MZ, Traore S, Lokman S, Nasri S, Aichouni N, Skiker I, Kamaoui I Abstract Gastrointestinal bleedings caused by small intestinal tumors are rare and difficult to diagnose because they are not easy to access to the conventional endoscopy. We report two cases, one of them from proximal jejunum and the...
Related Articles[Un- and dedifferentiated endometrial carcinoma : A rare entity with a wide range of differential diagnosis]. Pathologe. 2019 Nov;40(6):609-618 Authors: Höhn AK, Brambs CE, Opitz S, Erber R, Hartmann A, Horn LC Abstract Dedifferentiated endometrial carcinomas (ECs) are composed of undifferentiated EC and a FIGO grade 1 or 2 endometrioid carcinoma. The undifferentiated component represents a malignant epithelial neoplasm with no obvious...
Related ArticlesThe Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs. Nature. 2019 10;574(7776):127-131 Authors: van der Velden DL, Hoes LR, van der Wijngaart H, van Berge Henegouwen JM, van Werkhoven E, Roepman P, Schilsky RL, de Leng WWJ, Huitema ADR, Nuijen B, Nederlof PM, van Herpen CML, de Groot DJA, Devriese LA, Hoeben A, de Jonge MJA, Chalabi M, Smit EF, de Langen AJ, Mehra N, Labots M, Kapiteijn E, Sleijfer S, Cuppen E, Verheul...
Related ArticlesParoxysmal Hypertension Associated With Urination. Hypertension. 2019 11;74(5):1068-1074 Authors: Lou Y, Fan L, Hou X, Dominiczak AF, Wang JG, Staessen JA, Almustafa B, Ching S, Persu A, Bursztyn M, Cai J, Zhang H PMID: 31564165 [PubMed - indexed for MEDLINE]
Related Articles18F-FDG PET/CT in Metastatic Extramammary Paget's Disease. Clin Nucl Med. 2019 Oct;44(10):808-809 Authors: Khoo ACH, Yeoh KW Abstract Extramammary Paget's disease (EMPD) is a rare disease with an estimated prevalence of 0.1 to 2.4 per 1,000,000 person-years. Metastatic EMPD has a poor prognosis with a 5-year survival of approximately 7%. Local therapy is the only curative option with surgery being recommended for resectable disease....
Related ArticlesNivolumab-Induced Pneumonitis in Patient With Metastatic Melanoma Showing Complete Remission on 18F-FDG PET/CT. Clin Nucl Med. 2019 Oct;44(10):806-807 Authors: Razzouk-Cadet M, Picard A, Grangeon-Chapon C, Lacour JP, Montaudié H Abstract A 49-year-old patient with metastatic melanoma was treated with nivolumab (Opdivo). An early F-FDG PET/CT after 2 cycles showed a progressive metabolic disease. A 4-month optimal follow-up F-FDG PET/CT...
Related ArticlesMultidisciplinary approach to rare primary cardiac sarcoma: a case report and review. BMC Cancer. 2019 May 31;19(1):529 Authors: Vaitiekiene A, Vaitiekus D, Urbonaite L, Jankauskas A, Portacenko J, Lapinskas T, Benetis R, Siudikas A, Veikutiene A, Poskiene L, Kavoliuniene A, Janciauskiene R, Jarusevicius L, Juozaityte E, Zaliunas R, Ereminiene E Abstract BACKGROUND: Undifferentiated pleomorphic sarcoma is a very rare and aggressive...
Related ArticlesElevated X-linked inhibitor of apoptosis protein (XIAP) expression uncovers detrimental prognosis in subgroups of neoadjuvant treated and T-cell rich esophageal adenocarcinoma. BMC Cancer. 2019 May 31;19(1):531 Authors: Schiffmann LM, Göbel H, Löser H, Schorn F, Werthenbach JP, Fuchs HF, Plum PS, Bludau M, Zander T, Schröder W, Bruns CJ, Kashkar H, Quaas A, Gebauer F Abstract BACKGROUND: Molecular markers predicting survival in esophageal...
Related ArticlesNuclear Receptors Are Differentially Expressed and Activated in KAIMRC1 Compared to MCF7 and MDA-MB231 Breast Cancer Cells. Molecules. 2019 May 28;24(11): Authors: Nehdi A, Ali R, Alhallaj A, Alzahrani H, Samman N, Mashhour A, Baz O, Barhoumi T, Alghanem B, Khan A, Alriyees L, Boudjelal M Abstract We recently established a KAIMRC1 cell line that has unique features compared to the known breast cancer cell lines, MCF7 and MDA-MB231. To...
Related ArticlesTracheal Lymphoepithelioma-Like Carcinoma on FDG PET/CT. Clin Nucl Med. 2019 Oct;44(10):801-803 Authors: Shao D, Ding W, Wang S, Liang J, Wang S Abstract Lymphoepithelioma-like carcinoma (LELC) in the trachea is an extremely rare disease. We present a case of a 64-year-old man with FDG-avid tracheal LELC on F-FDG PET/CT. Despite its rarity, LELC in the trachea should be considered as one of the possibilities in patients with a hypermetabolic...
Related ArticlesA rare and overlooked mechanical complication of partial nephrectomy: Accelerated hypertension due to renal artery stenosis. Turk Kardiyol Dern Ars. 2019 Apr;47(3):235-238 Authors: Şener YZ, Canpolat U, Yazıcı MS, Atalar E Abstract Secondary hypertension accounts for 5% to 10% of all hypertensive cases, and renal artery stenosis is one of the most common causes of secondary hypertension. Although atherosclerotic vascular disease and fibromuscular...
Related ArticlesParanoid Syndrome as the First Sign of Central Neurocytoma: A Case Report. J Psychiatr Pract. 2018 Sep;24(5):359-363 Authors: Karakula-Juchnowicz H, Morylowska-Topolska J, Juchnowicz D, Korzeniowska A, Krukow P, Rola R Abstract Central neurocytoma (CN), first described in 1982 by Hassoun and colleagues, is a rare tumor accounting for 0.25% to 0.5% of all tumors of the central nervous system. The tumor is a neoplasm of neuroepithelial...
Related ArticlesPrognostic factors in the surgical treatment of intracanalicular primary optic nerve sheath meningiomas. J Neurosurg. 2018 09 21;131(2):481-488 Authors: Rassi MS, Prasad S, Can A, Pravdenkova S, Almefty R, Al-Mefty O Abstract OBJECTIVE: Although meningiomas frequently involve the optic nerve, primary optic nerve sheath meningiomas (ONSMs) are rare, accounting for only 1% of all meningiomas. Given the high risk of vision loss with these...
Related ArticlesActivating PRKACB somatic mutation in cortisol-producing adenomas. JCI Insight. 2018 04 19;3(8): Authors: Espiard S, Knape MJ, Bathon K, Assié G, Rizk-Rabin M, Faillot S, Luscap-Rondof W, Abid D, Guignat L, Calebiro D, Herberg FW, Stratakis CA, Bertherat J Abstract Mutations in the gene encoding the protein kinase A (PKA) catalytic subunit α have been found to be responsible for cortisol-producing adenomas (CPAs). In this study, we...
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