Pharmaceutics, Vol. 11, Pages 566: Population Pharmacokinetics Modelling and Simulation of Mitotane in Patients with Adrenocortical Carcinoma: An Individualized Dose Regimen to Target All Patients at Three Months? Pharmaceutics doi: 10.3390/pharmaceutics11110566 Authors: Yoann Cazaubon Yohann Talineau Catherine Feliu Céline Konecki Jennifer Russello Olivier Mathieu Zoubir Djerada Mitotane is the most effective agent in post-operative treatment of adrenocortical carcinoma....
Thu Oct 31, 2019 02:00
Micromachines, Vol. 10, Pages 745: Measurement of Heat Dissipation and Thermal-Stability of Power Modules on DBC Substrates with Various Ceramics by SiC Micro-Heater Chip System and Ag Sinter Joining Micromachines doi: 10.3390/mi10110745 Authors: Dongjin Kim Yasuyuki Yamamoto Shijo Nagao Naoki Wakasugi Chuantong Chen Katsuaki Suganuma This study introduced the SiC micro-heater chip as a novel thermal evaluation device for next-generation power modules and to evaluate the...
Thu Oct 31, 2019 02:00
Toxins, Vol. 11, Pages 634: Trichothecenes in Cereal Grains – An Update Toxins doi: 10.3390/toxins11110634 Authors: Nora A. Foroud Danica Baines Tatiana Y. Gagkaeva Nehal Thakor Ana Badea Barbara Steiner Maria Bürstmayr Hermann Bürstmayr Trichothecenes are sesquiterpenoid mycotoxins produced by fungi from the order Hypocreales, including members of the Fusarium genus that infect cereal grain crops. Different trichothecene-producing Fusarium species and strains have...
Thu Oct 31, 2019 02:00
Technologies, Vol. 7, Pages 78: From Undesired Flaws to Esthetic Assets: A Digital Framework Enabling Artistic Explorations of Erroneous Geometric Features of Robotically Formed Molds Technologies doi: 10.3390/technologies7040078 Authors: Malgorzata A. Zboinska Until recently, digital fabrication research in architecture has aimed to eliminate manufacturing errors. However, a novel notion has just been established—intentional computational infidelity. Inspired by this notion,...
Thu Oct 31, 2019 02:00
Water, Vol. 11, Pages 2284: Numerical Prediction of Background Buildup of Salinity Due to Desalination Brine Discharges into the Northern Arabian Gulf Water doi: 10.3390/w11112284 Authors: Aaron C. Chow Wilbert Verbruggen Robin Morelissen Yousef Al-Osairi Poornima Ponnumani Haitham M. S. Lababidi Bader Al-Anzi E. Eric Adams Brine discharges from desalination plants into low-flushing water bodies are challenging from the point of view of dilution, because of the possibility...
Thu Oct 31, 2019 02:00
Applied Sciences, Vol. 9, Pages 4636: Low-Loss Active Grid Impedance Cancellation in Grid-Connected Inverters with LCL Filter Applied Sciences doi: 10.3390/app9214636 Authors: Yuqi Peng Yuanbin He Lijun Hang Distributed power inverters with inductive capacitive–inductive (LCL) filters have become popular in distributed power generation system. However, due to unknown grid impedance, the inverters are confronted with challenges of local filter resonance, poor power quality,...
Thu Oct 31, 2019 02:00
Crystals, Vol. 9, Pages 574: Thermo-Optical Generation of Particle-Like Structures in Frustrated Chiral Nematic Film Crystals doi: 10.3390/cryst9110574 Authors: Sergey Shvetsov Tetiana Orlova Alexander V. Emelyanenko Alexander Zolot’ko The creation of metastable particle-like structures in frustrated (unwound) chiral nematic film containing light-absorbing additive is studied. It is shown that such localized structures can be generated by the thermo-optical action of a focused...
Thu Oct 31, 2019 02:00
Applied Sciences, Vol. 9, Pages 4639: Improving Hybrid CTC/Attention Architecture with Time-Restricted Self-Attention CTC for End-to-End Speech Recognition Applied Sciences doi: 10.3390/app9214639 Authors: Long Wu Ta Li Li Wang Yonghong Yan As demonstrated in hybrid connectionist temporal classification (CTC)/Attention architecture, joint training with a CTC objective is very effective to solve the misalignment problem existing in the attention-based end-to-end automatic speech...
Thu Oct 31, 2019 02:00
Cancers, Vol. 11, Pages 1695: Dual PDK1/Aurora Kinase A Inhibitors Reduce Pancreatic Cancer Cell Proliferation and Colony Formation Cancers doi: 10.3390/cancers11111695 Authors: Ilaria Casari Alice Domenichini Simona Sestito Emily Capone Gianluca Sala Simona Rapposelli Marco Falasca Deregulation of different intracellular signaling pathways is a common feature in cancer. Numerous studies indicate that persistent activation of the phosphoinositide 3-kinase (PI3K) pathway...
Thu Oct 31, 2019 02:00
Metals, Vol. 9, Pages 1177: AFM Study of Pyrite Oxidation and Xanthate Adsorption in the Presence of Seawater Salts Metals doi: 10.3390/met9111177 Authors: Álvaro Paredes Sergio M. Acuña Pedro G. Toledo The effect of seawater ions presents a great challenge to theories about mechanisms of pyrite oxidation, collector adsorption, and surface reactions. As the use of seawater is key to the sustainability of the mining industry in regions without fresh water, there is a need to study...
Thu Oct 31, 2019 02:00
Applied Sciences, Vol. 9, Pages 4637: A Novel Piezoelectric Ceramic Actuator with Scissoring Composite Vibration for Medical Applications Applied Sciences doi: 10.3390/app9214637 Authors: Jingjing Yang Qiang Zhang Taojin Xu This paper presents a novel scissoring composite actuator which can successfully degenerate longitudinal vibration into scissoring vibration at actuator tips for potential medical applications. The proposed actuator consists of back mass, multilayer piezoceramic...
Thu Oct 31, 2019 02:00
Remote Sensing, Vol. 11, Pages 2562: Nitrogen and Phosphorus effect on Sun-Induced Fluorescence and Gross Primary Productivity in Mediterranean Grassland Remote Sensing doi: 10.3390/rs11212562 Authors: Martini Pacheco-Labrador Perez-Priego van der Tol Madany Julitta Rossini Reichstein Christiansen Rascher Moreno Martín Yang Carrara Guan González-Cascón Migliavacca Sun-Induced fluorescence at 760 nm (F760) is increasingly...
Thu Oct 31, 2019 02:00
Cells, Vol. 8, Pages 1363: Laquinimod Supports Remyelination in Non-Supportive Environments Cells doi: 10.3390/cells8111363 Authors: Stella Nyamoya Julia Steinle Uta Chrzanowski Joel Kaye Christoph Schmitz Cordian Beyer Markus Kipp Inflammatory demyelination, which is a characteristic of multiple sclerosis lesions, leads to acute functional deficits and, in the long term, to progressive axonal degeneration. While remyelination is believed to protect axons, the endogenous-regenerative...
Thu Oct 31, 2019 02:00
Nutrients, Vol. 11, Pages 2608: Association between the Prognostic Nutritional Index and Dietary Intake in Community-Dwelling Older Adults with Heart Failure: Findings from NHANES III Nutrients doi: 10.3390/nu11112608 Authors: Elisabeth L. P. Sattler Yuta Ishikawa Rupal Trivedi-Kapoor Donglan Zhang Arshed A. Quyyumi Sandra B. Dunbar The objective of this study was to examine the association between nutritional status and dietary intake in community-dwelling older adults...
Thu Oct 31, 2019 02:00
Materials, Vol. 12, Pages 3590: Influence of Current Feeding Position of Duplex Current Feeding MIG Welding on Droplet Heat Quantity Materials doi: 10.3390/ma12213590 Authors: Atsuhito Aoki Shinichi Tashiro Hideaki Kurokawa Manabu Tanaka Pure argon metal inert gas (MIG) welding is expected to offer the possibility to obtain high toughness weld joints. However, due to its arc instability and low wettability, it is difficult to apply pure argon MIG to a practical welding structure....
Thu Oct 31, 2019 02:00
Applied Sciences, Vol. 9, Pages 4638: Machine-Learning-Based Classification Approaches toward Recognizing Slope Stability Failure Applied Sciences doi: 10.3390/app9214638 Authors: Moayedi Bui Kalantar Foong In this paper, the authors investigated the applicability of combining machine-learning-based models toward slope stability assessment. To do this, several well-known machine-learning-based methods, namely multiple linear regression (MLR), multi-layer perceptron (MLP),...
Thu Oct 31, 2019 02:00
Diversity, Vol. 11, Pages 205: Functional Traits Co-Occurring with Mobile Genetic Elements in the Microbiome of the Atacama Desert Diversity doi: 10.3390/d11110205 Authors: Sáenz Airo Schulze-Makuch Schloter Vestergaard Mobile genetic elements (MGEs) play an essential role in bacterial adaptation and evolution. These elements are enriched within bacterial communities from extreme environments. However, very little is known if specific genes co-occur with MGEs in extreme...
Thu Oct 31, 2019 02:00
Materials, Vol. 12, Pages 3589: Electronic, Mechanical and Elastic Anisotropy Properties of X-Diamondyne (X = Si, Ge) Materials doi: 10.3390/ma12213589 Authors: Qingyang Fan Zhongxing Duan Yanxing Song Wei Zhang Qidong Zhang Sining Yun The three-dimensional (3D) diamond-like semiconductor materials Si-diamondyne and Ge-diamondyne (also called SiC4 and GeC4) are studied utilizing density functional theory in this work, where the structural, elastic, electronic and mechanical...
Thu Oct 31, 2019 02:00
Micromachines, Vol. 10, Pages 744: Recent Advances in Continuous-Flow Particle Manipulations Using Magnetic Fluids Micromachines doi: 10.3390/mi10110744 Authors: Xiangchun Xuan Magnetic field-induced particle manipulation is simple and economic as compared to other techniques (e.g., electric, acoustic, and optical) for lab-on-a-chip applications. However, traditional magnetic controls require the particles to be manipulated being magnetizable, which renders it necessary to magnetically...
Thu Oct 31, 2019 02:00
Fluids, Vol. 4, Pages 187: Investigations of Evaporative Cooling and Turbulence Flame Interaction Modeling in Ethanol Turbulent Spray Combustion Using Tabulated Chemistry Fluids doi: 10.3390/fluids4040187 Authors: Fernando Luiz Sacomano Filho Louis Dressler Arash Hosseinzadeh Amsini Sadiki Guenther Carlos Krieger Filho Evaporative cooling effects and turbulence flame interaction are analyzed in the large eddy simulation (LES) context for an ethanol turbulent spray flame....
Thu Oct 31, 2019 02:00
Remote Sensing, Vol. 11, Pages 2561: An Empirical Assessment of Angular Dependency for RedEdge-M in Sloped Terrain Viticulture Remote Sensing doi: 10.3390/rs11212561 Authors: Chizhang Gong Henning Buddenbaum Rebecca Retzlaff Thomas Udelhoven For grape canopy pixels captured by an unmanned aerial vehicle (UAV) tilt-mounted RedEdge-M multispectral sensor in a sloped vineyard, an in situ Walthall model can be established with purely image-based methods. This was derived from RedEdge-M...
Thu Oct 31, 2019 02:00
Land, Vol. 8, Pages 162: ‘Not One More Bloody Acre’: Land Restitution and the Treaty of Waitangi Settlement Process in Aotearoa New Zealand Land doi: 10.3390/land8110162 Authors: Matthew Wynyard Te Tiriti o Waitangi, signed between Māori rangatira (chiefs) and the British Crown in 1840 guaranteed to Māori the ‘full, exclusive and undisturbed possession of their lands’. In the decades that followed, Māori were systematically dispossessed of all but a fraction of their...
Thu Oct 31, 2019 02:00
Entropy, Vol. 21, Pages 1070: Nonreference Image Quality Evaluation Algorithm Based on Wavelet Convolutional Neural Network and Information Entropy Entropy doi: 10.3390/e21111070 Authors: Jinhua Liu Mulian Xu Xinye Xu Yuanyuan Huang The image quality evaluation method, based on the convolutional neural network (CNN), achieved good evaluation performance. However, this method can easily lead the visual quality of image sub-blocks to change with the spatial position after the...
Thu Oct 31, 2019 02:00
Galaxies, Vol. 7, Pages 86: Features of Structure and Absorption in the Jet-Launching Region of M87 Galaxies doi: 10.3390/galaxies7040086 Authors: Wei Zhao Xiaoyu Hong Tao An Xiaofeng Li Xiaopeng Cheng Fang Wu M87 is one of the best available source for studying the AGN jet-launching region. To enrich our knowledge of this region, with quasi-simultaneous observations using VLBA at 22, 43 and 86 GHz, we capture the images of the radio jet in M87 on a scale within several...
Thu Oct 31, 2019 02:00
Viruses, Vol. 11, Pages 1007: Metabolomic Analysis of Influenza A Virus A/WSN/1933 (H1N1) Infected A549 Cells during First Cycle of Viral Replication Viruses doi: 10.3390/v11111007 Authors: Xiaodong Tian Kun Zhang Jie Min Can Chen Ying Cao Chan Ding Wenjun Liu Jing Li Influenza A virus (IAV) has developed strategies to utilize host metabolites which, after identification and isolation, can be used to discover the value of immunometabolism. During this study, to mimic...
Thu Oct 31, 2019 02:00
Crystals, Vol. 9, Pages 573: Crystal Structure, Raman Spectroscopy and Dielectric Properties of New Semiorganic Crystals Based on 2-Methylbenzimidazole Crystals doi: 10.3390/cryst9110573 Authors: E. V. Balashova F. B. Svinarev A. A. Zolotarev A. A. Levin P. N. Brunkov V. Yu. Davydov A. N. Smirnov A. V. Redkov G. A. Pankova B. B. Krichevtsov New single crystals, based on 2-methylbenzimidazole (MBI), of MBI-phosphite (C16H24N4O7P2), MBI-phosphate-1 (C16H24N4O9P2),...
Thu Oct 31, 2019 02:00
Chemosensors, Vol. 7, Pages 53: Noble Metal Nanoparticles-Based Colorimetric Biosensor for Visual Quantification: A Mini Review Chemosensors doi: 10.3390/chemosensors7040053 Authors: Lu Yu Na Li Nobel metal can be used to form a category of nanoparticles, termed noble metal nanoparticles (NMNPs), which are inert (resistant to oxidation/corrosion) and have unique physical and optical properties. NMNPs, particularly gold and silver nanoparticles (AuNPs and AgNPs), are highly accurate...
Thu Oct 31, 2019 02:00
Universe, Vol. 5, Pages 216: Gravitational Fluctuations as an Alternative to Inflation II. CMB Angular Power Spectrum Universe doi: 10.3390/universe5110216 Authors: Herbert W. Hamber Lu Heng Sunny Yu Power spectra always play an important role in the theory of inflation. In particular, the ability to reproduce the galaxy matter power spectrum P ( k ) and the CMB temperature angular power spectrum C l ’s to high accuracy is often considered a triumph of inflation....
Thu Oct 31, 2019 02:00
Sensors, Vol. 19, Pages 4737: Spectroscopic Understanding of SnO2 and WO3 Metal Oxide Surfaces with Advanced Synchrotron Based; XPS-UPS and Near Ambient Pressure (NAP) XPS Surface Sensitive Techniques for Gas Sensor Applications under Operational Conditions Sensors doi: 10.3390/s19214737 Authors: Engin Ciftyürek Břetislav Šmíd Zheshen Li Vladimír Matolín Klaus Schierbaum The most promising and utilized chemical sensing materials, WO3 and SnO2 were characterized by means advanced...
Thu Oct 31, 2019 02:00
Pharmaceutics, Vol. 11, Pages 565: Evaluation of Sucrose Laurate as an Intestinal Permeation Enhancer for Macromolecules: Ex Vivo and In Vivo Studies Pharmaceutics doi: 10.3390/pharmaceutics11110565 Authors: Fiona McCartney Mónica Rosa David J. Brayden Oral delivery of macromolecules requires permeation enhancers (PEs) adaptable to formulation. Sucrose laurate (SL) (D1216), a food grade surfactant, was assessed in Caco-2 monolayers, isolated rat intestinal tissue mucosae, and rat...
Thu Oct 31, 2019 02:00
Cells, Vol. 8, Pages 1362: Phosphorylation of TIP3 Aquaporins during Phaseolus vulgaris Embryo Development Cells doi: 10.3390/cells8111362 Authors: Mark J. Daniels Mark Yeager The membrane phosphoproteome in plant seed changes dynamically during embryo development. We examined the patterns of Phaseolus vulgaris (common bean) seed membrane protein phosphorylation from the mid-maturation stage until two days after germination. Serine and threonine phosphorylation declined during seed...
Thu Oct 31, 2019 02:00
Metabolites, Vol. 9, Pages 257: Inter-Laboratory Comparison of Metabolite Measurements for Metabolomics Data Integration Metabolites doi: 10.3390/metabo9110257 Authors: Yoshihiro Izumi Fumio Matsuda Akiyoshi Hirayama Kazutaka Ikeda Yoshihiro Kita Kanta Horie Daisuke Saigusa Kosuke Saito Yuji Sawada Hiroki Nakanishi Nobuyuki Okahashi Masatomo Takahashi Motonao Nakao Kosuke Hata Yutaro Hoshi Motohiko Morihara Kazuhiro Tanabe Takeshi Bamba Yoshiya...
Thu Oct 31, 2019 02:00
Minerals, Vol. 9, Pages 671: Using Reservoir Geology and Petrographic Observations to Improve CO2 Mineralization Estimates; Examples from the Johansen Formation, North Sea, Norway Minerals doi: 10.3390/min9110671 Authors: Anja Sundal Helge Hellevang Reservoir characterization specific to CO2 storage is challenging due to the dynamic interplay of physical and chemical trapping mechanisms. The mineralization potential for CO2 in a given siliciclastic sandstone aquifer is controlled...
Thu Oct 31, 2019 02:00
Applied Sciences, Vol. 9, Pages 4634: A Novel Sensing Strategy Based on Energy Detector for Spectrum Sensing Applied Sciences doi: 10.3390/app9214634 Authors: Hai Huang Jia Zhu Junsheng Mu Sensing strategy directly influences the sensing accuracy of a spectrum sensing scheme. As a result, the optimization of a sensing strategy appears to be of great significance for accuracy improvement in spectrum sensing. Motivated by this, a novel sensing strategy is proposed in this paper,...
Thu Oct 31, 2019 02:00
Nanomaterials, Vol. 9, Pages 1549: Graphene IoNanofluids, Thermal and Structural Characterization Nanomaterials doi: 10.3390/nano9111549 Authors: C. Hermida-Merino A.B. Pereiro J.M.M. Araújo C. Gracia-Fernández Javier P. Vallejo Luis Lugo M.M. Piñeiro Graphene is considered a promising substance in applications related to the capture and reduction of the environmental impact of fluorinated gases. However, further research is still required to explore all related possibilities....
Thu Oct 31, 2019 02:00
IJMS, Vol. 20, Pages 5436: The Systemic Immune Response to Collagen-Induced Arthritis and the Impact of Bone Injury in Inflammatory Conditions International Journal of Molecular Sciences doi: 10.3390/ijms20215436 Authors: José H. Teixeira Andreia M. Silva Maria Inês Almeida Mafalda Bessa-Gonçalves Carla Cunha Mário A. Barbosa Susana G. Santos Rheumatoid arthritis (RA) is a systemic disease that affects the osteoarticular system, associated with bone fragility and increased...
Thu Oct 31, 2019 02:00
IJMS, Vol. 20, Pages 5437: Silenced ZNF154 Is Associated with Longer Survival in Resectable Pancreatic Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20215437 Authors: Felix Wiesmueller Josephin Kopke Daniela Aust Janine Roy Andreas Dahl Christian Pilarsky Robert Grützmann Pancreatic cancer has become the third leading cause of cancer-related death in the Western world despite advances in therapy of other cancerous lesions. Late diagnosis due to...
Thu Oct 31, 2019 02:00
Sustainability, Vol. 11, Pages 6056: New Perspectives for Mapping Global Population Distribution Using World Settlement Footprint Products Sustainability doi: 10.3390/su11216056 Authors: Daniela Palacios-Lopez Felix Bachofer Thomas Esch Wieke Heldens Andreas Hirner Mattia Marconcini Alessandro Sorichetta Julian Zeidler Claudia Kuenzer Stefan Dech Andrew J. Tatem Peter Reinartz In the production of gridded population maps, remotely sensed, human settlement...
Thu Oct 31, 2019 02:00
Microorganisms, Vol. 7, Pages 516: The Signature Microbiota Drive Rumen Function Shifts in Goat Kids Introduced to Solid Diet Regimes Microorganisms doi: 10.3390/microorganisms7110516 Authors: Xiaokang Lv Jianmin Chai Qiyu Diao Wenqin Huang Yimin Zhuang Naifeng Zhang The feeding regime of early, supplementary solid diet improved rumen development and production in goat kids. However, the signature microbiota responsible for linking dietary regimes to rumen function shifts...
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