Pre-, intra-, and/or postoperative arterial and venous thromboembolism prophylaxis for breast surgery: Systematic review and meta-analysis. J Plast Reconstr Aesthet Surg. 2019 Oct 02;: Authors: Klifto KM, Gurno CF, Major M, Seal SM, Sacks JM, Rosson GD, Manahan MA Abstract Both thromboembolism and excessive bleeding following breast surgery could result in multiple surgical procedures, breast reconstruction failure, or even mortality. This systematic...
Vitamin D plasma concentration and vitamin D receptor genetic variants confer risk of asthma: A comparison study of Taiwanese and Mongolian populations. World Allergy Organ J. 2019 Nov;12(11):100076 Authors: Munkhbayarlakh S, Kao HF, Hou YI, Tuvshintur N, Bayar-Ulzii B, Narantsetseg L, Wang JY, Hsin Wu LS Abstract Background: Recent reports have suggested that lower vitamin D serum levels are associated with susceptibility to and severity of asthma...
Time to revisit the definition and clinical criteria for anaphylaxis? World Allergy Organ J. 2019 Oct;12(10):100066 Authors: Turner PJ, Worm M, Ansotegui IJ, El-Gamal Y, Rivas MF, Fineman S, Geller M, Gonzalez-Estrada A, Greenberger PA, Tanno LK, Borges MS, Senna G, Sheikh A, Thong BY, Ebisawa M, Cardona V, WAO Anaphylaxis Committee PMID: 31719946 [PubMed]
Association of the maternal microbiome in Japanese pregnant women with the cumulative prevalence of dermatitis in early infancy: A pilot study from the Chiba study of Mother and Child Health birth cohort. World Allergy Organ J. 2019 Oct;12(10):100065 Authors: Tanabe H, Sakurai K, Kato T, Kawasaki Y, Nakano T, Yamaide F, Taguchi-Atarashi N, Watanabe M, Ochiai S, Ohno H, Fukuoka H, Shimojo N, Mori C Abstract Background: The prenatal maternal microbiome,...
MiR-421 promotes the development of osteosarcoma by regulating MCPIP1 expression. Cancer Biol Ther. 2019 Nov 12;:1-10 Authors: Ren Z, He M, Shen T, Wang K, Meng Q, Chen X, Zhou L, Han Y, Ji C, Liu S, Fu Q Abstract Despite improvements in surgical resection and adjuvant chemotherapy, the prognosis and outcomes of patients with osteosarcoma remains poor due to the occurrence of metastasis or relapse. Monocyte chemoattractant protein-1-induced protein-1...
Robustness analysis of decoding SSVEPs in humans with head movements using a moving visual flicker. J Neural Eng. 2019 Nov 13;: Authors: Kanoga S, Nakanishi M, Murai A, Tada M, Kanemura A Abstract OBJECTIVE: The emergence of mobile electroencephalogram (EEG) platforms have expanded the use cases of brain--computer interfaces (BCIs) from laboratory-oriented experiments to our daily life. In challenging situations where humans' natural behaviors such as...
LncRNA SNHG7 is an Oncogenic Biomarker Interacting with MicroRNA-193b in Colon Carcinogenesis. Clin Lab. 2019 Nov 01;65(11): Authors: Liu KL, Wu J, Li WK, Li NS, Li Q, Lao YQ Abstract BACKGROUND: The expression and significance of small nucleolar RNA host gene 7 (SNHG7) in early-stage colon carcinogenesis remains unclear. METHODS: The level of SNHG7 and microRNA-193b (miR-193b) was detected by qRT-PCR in colon tumor tissues and cells. The interaction...
Blood Clot Identification Procedures in Clinical Laboratory Sampling. Clin Lab. 2019 Nov 01;65(11): Authors: Delianu C, Foia L, Hurjui LL, Vlad CE, Tuchiluș C, Tărniceriu CC, Stolniceanu CR, Toma V Abstract BACKGROUND: Monitoring of anticoagulation therapy is based on screening tests: prothrombin time (PT) and activated partial thromboplastin time (APTT). The accidental presence of a clot in the coagulation samples determines a false prolongation of...
32 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/11/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Use of nanoparticles in skeletal tissue regeneration and engineering. Histol Histopathol. 2019 Nov 13;:18184 Authors: Filippi M, Born G, Felder-Flesch D, Scherberich A Abstract Bone and osteochondral defects represent one of the major causes of disabilities in the world. Derived from traumas and degenerative pathologies, these lesions cause severe pain, joint deformity, and loss of joint motion. The standard treatments in clinical practice present several...
Thu Nov 14, 2019 19:22
Phrases in noise test (PINT) Brazil: effectiveness of the test in children with hearing loss. Braz J Otorhinolaryngol. 2019 Sep 18;: Authors: Jacob RTS, Souza COE, Rosa BC, Santos LGD, Paccola ECM, Alvarenga BG, Lauris JRP Abstract INTRODUCTION: One of the main implications of hearing impairment is the difficulty in perceiving speech sounds, especially in noisy environments. Thus, the frequency-modulated system is considered an important educational...
Prevalence and resistance profiles of vancomycin-resistant enterococcal isolates in Iran; an eight-month report from nine major cities. Infect Disord Drug Targets. 2019 Nov 11;: Authors: Armin S, Zahedani SS, Rahbar M, Azimi L Abstract BACKGROUND: Enterococcal infections comprise a wide range of diseases with increasing importance due to the growing frequency of health-care-associated infections and increasing incidence of antimicrobial resistance. Vancomycin-resistant...
Serum Vitamin D Levels in Chronic Hepatitis B Patients Before and During Treatment. Infect Disord Drug Targets. 2019 Nov 11;: Authors: Mohamed AA, Abdo S, Said E, Agawy WE, Awad P, Mohamed Ghanem AI, Khattab RA, El-Damasy DA, Elkadeem M, Abd-Elsalam S Abstract BACKGROUND & AIMS: Hepatitis B is a potentially life-threatening liver infection and it is a major global health problem. Over the past decade, numerous studies have reported that patients...
Social media for the regional anesthesiologist: can we use it in place of medical journals? Reg Anesth Pain Med. 2019 Nov 11;: Authors: Tran BW, Dhillon SK, Overholt AR, Huntoon M Abstract The regional anesthesia community regularly uses social media for advocacy and education. Well-known leaders in the field are willing to share their opinions with colleagues in a public forum. Some visionaries predict that the influence of social media will soon transcend...
New landmarks in endonasal surgery: from nasal bone to anterior cribriform plate including branches of anterior ethmoidal artery and nerve and terminal nerve. Int Forum Allergy Rhinol. 2019 Nov 13;: Authors: Roussel LM, Patron V, Maubert E, Escalard C, Goux D, Beaudouin V, Lechapt E, Moreau S, Hitier M Abstract BACKGROUND: Despite the development of anterior skull base surgery, the anatomy of the nasal bone and anterior cribriform plate remains unclear....
Does Nationality Matter for the Gunshot Brain Injury? Ten-Year Retrospective Observational Cadaveric Comparative Study for Gunshot TBI between Greece and Bulgaria. Korean J Neurotrauma. 2019 Oct;15(2):95-102 Authors: Nikova AS, Karakasi MV, Pavlidis P, Birbilis T, Dimitrov I Abstract Objective: Penetrating brain trauma (PBT) caused by gunshot is one of the most lethal traumatic brain injuries (TBIs) and its management and confrontation is of great importance....
Metastatic Disease to Clivus: Biopsy or Not? Cureus. 2019 Sep 14;11(9):e5658 Authors: Cathel A, Khan YR, Blais D, Mahato B, Mahato D Abstract Due to the aggressive nature of hepatocellular carcinoma (HCC), most patients succumb to disease before any distant metastasis, such as to the central nervous system (CNS), can occur. Thus only a handful of cases of metastasis to the skull base have been described. After a thorough review of the available literature...
The Comprehensive AO CMF Classification System for Mandibular Fractures: A Multicenter Validation Study. Craniomaxillofac Trauma Reconstr. 2019 Dec;12(4):254-265 Authors: Mittermiller PA, Bidwell SS, Thieringer FM, Cornelius CP, Trickey AW, Kontio R, Girod S, and the AO Trauma Classification Study Group Abstract The AO CMF has recently launched the first comprehensive classification system for craniomaxillofacial (CMF) fractures. The AO CMF classification...
Normofractionated stereotactic radiotherapy versus CyberKnife-based hypofractionation in skull base meningioma: a German and Italian pooled cohort analysis. Radiat Oncol. 2019 Nov 12;14(1):201 Authors: Alfredo C, Carolin S, Güliz A, Anne K, Antonio P, Alberto C, Stefano P, Antonino G, Harun B, Markus K, Franziska M, Phuong N, Franziska L, Peter V, Volker B, David K Abstract BACKGROUND: This retrospective German and Italian multicenter analysis aimed...
Related ArticlesComplications Related to Laryngeal Mask Airway Use and a Postoperative Diagnosis of Reinke Edema: A Case Study. AANA J. 2018 Dec;86(6):443-445 Authors: Cuevas LDK, Bonds UCR, Powell UCA Abstract This case report describes a partial airway obstruction encountered with the use of a laryngeal mask airway and the inability to deliver adequate tidal volumes despite manipulation and device exchange. The patient later received a diagnosis of...
Indication of CPAP without a sleep study in patients with high pretest probability of obstructive sleep apnea. Sleep Breath. 2019 Nov 12;: Authors: Nigro CA, Borsini E, Dibur E, Larrateguy L, Cazaux A, Elias C, de la Vega M, Berrozpe C, Maggi S, Grandval S, Cambursano H, Visentini D, Blanco M, Ernst G, Bledel I, Nogueira F Abstract OBJECTIVE: To evaluate the performance of clinical criteria (CC) for diagnosis and initiation of empirical treatment with...
Paget's disease of the nipple in a Her2-positive breast cancer xenograft model. Breast Cancer Res Treat. 2019 Nov 13;: Authors: Drews-Elger K, Sandoval-Leon AC, Ergonul AB, Jegg AM, Gomez-Fernandez C, Miller PC, El-Ashry D, Lippman ME Abstract PURPOSE: Paget's disease (PD) of the breast is an uncommon disease of the nipple usually accompanied by an underlying carcinoma, often HER2 + , and accounting for 0.5-5% of all breast cancer. To date, histogenesis...
Mechanism, safety and efficacy of three tyrosine kinase inhibitors lapatinib, neratinib and pyrotinib in HER2-positive breast cancer. Am J Cancer Res. 2019;9(10):2103-2119 Authors: Xuhong JC, Qi XW, Zhang Y, Jiang J Abstract The incidence of breast cancer ranks first among female malignant tumors that affect women's health. Epidermal growth factor receptor (EGFR) family overexpression, especially human epidermal receptor2 (HER2), features prominently...
Clinicopathologic Characteristics of HER2-positive Pure Mucinous Carcinoma of the Breast. J Pathol Transl Med. 2019 Nov 13;: Authors: Jang Y, Jung H, Kim HN, Seo Y, Alsharif E, Nam SJ, Kim SW, Lee JE, Park YH, Cho EY, Cho SY Abstract Background: Pure mucinous carcinoma (PMC) is a rare type of breast cancer, estimated to represent 2% of invasive breast cancer. PMC is typically positive for estrogen receptors (ER) and progesterone receptors (PR) and negative...
Heterogeneity in influenza seasonality and vaccine effectiveness in Australia, Chile, New Zealand and South Africa: early estimates of the 2019 influenza season. Euro Surveill. 2019 Nov;24(45): Authors: Sullivan SG, Arriola CS, Bocacao J, Burgos P, Bustos P, Carville KS, Cheng AC, Chilver MB, Cohen C, Deng YM, El Omeiri N, Fasce RA, Hellferscee O, Huang QS, Gonzalez C, Jelley L, Leung VK, Lopez L, McAnerney JM, McNeill A, Olivares MF, Peck H, Sotomayor V, Tempia S, Vergara...
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A proposal for changes to the European Union syphilis surveillance case definition using evidence from evaluations in Ireland. Euro Surveill. 2019 Nov;24(45): Authors: Petty-Saphon N, Brady M, Cullen G, Cooney F, Downes P, Doyle S, Holder P, Lyons F, Igoe D Abstract Syphilis remains a disease of public health importance, with considerable health effects if not treated. Concurrent infection with syphilis and untreated HIV facilitates HIV transmission....
Thu Nov 14, 2019 17:40
Vector-borne transmission of Zika virus in Europe, southern France, August 2019. Euro Surveill. 2019 Nov;24(45): Authors: Giron S, Franke F, Decoppet A, Cadiou B, Travaglini T, Thirion L, Durand G, Jeannin C, L'Ambert G, Grard G, Noël H, Fournet N, Auzet-Caillaud M, Zandotti C, Aboukaïs S, Chaud P, Guedj S, Hamouda L, Naudot X, Ovize A, Lazarus C, de Valk H, Paty MC, Leparc-Goffart I Abstract On 1 October 2019, a locally-acquired Zika virus disease case...
Thu Nov 14, 2019 17:40
Performance of surveillance case definitions for respiratory syncytial virus infections through the sentinel influenza surveillance system, Portugal, 2010 to 2018. Euro Surveill. 2019 Nov;24(45): Authors: Sáez-López E, Pechirra P, Costa I, Cristóvão P, Conde P, Machado A, Rodrigues AP, Guiomar R Abstract BackgroundWell-established influenza surveillance systems (ISS) can be used for respiratory syncytial virus (RSV) surveillance. In Portugal, RSV cases...
Thu Nov 14, 2019 17:40
Impact of influenza vaccination programmes among the elderly population on primary care, Portugal, Spain and the Netherlands: 2015/16 to 2017/18 influenza seasons. Euro Surveill. 2019 Nov;24(45): Authors: Machado A, Mazagatos C, Dijkstra F, Kislaya I, Gherasim A, McDonald SA, Kissling E, Valenciano M, Meijer A, Hooiveld M, Nunes B, Larrauri A Abstract BackgroundTo increase the acceptability of influenza vaccine, it is important to quantify the overall...
Thu Nov 14, 2019 17:40
[Laryngectomy-still state of the art?] HNO. 2019 Nov 12;: Authors: Vahl JM, Schuler PJ, Greve J, Laban S, Knopf A, Hoffmann TK Abstract Total laryngectomy provides a curative approach for patients with advanced laryngeal and hypopharyngeal cancer without distant metastasis. Especially in stage cT4a disease, laryngectomy is superior to primary radio(chemo)therapy in retrospective studies. Further relevant indications for the procedure are tumor-related...
[Tonsil surgery in the federal states of Germany: similarities and differences. German version]. HNO. 2019 Nov 12;: Authors: Windfuhr JP, Chen YS Abstract BACKGROUND: Tonsillectomy remains a common procedure in Germany. However, demographic changes, the advent of tonsillotomy, and current guidelines may have an impact on the overall incidence. OBJECTIVE: To longitudinally evaluate the number of tonsillectomies, with (ATE) or without adenoidectomy...
[Tips for training assistants on preparing and conducting their board certification examination]. HNO. 2019 Nov 12;: Authors: Eichhorn T Abstract This article first discusses the general requirements for conducting board certification examinations as laid down in the specialty training regulations of the German State Chambers of Physicians. Concrete suggestions are made for training assistants concerning selection of the specialist literature to be processed...
Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review. CNS Drugs. 2019 Nov 13;: Authors: Besag FMC, Vasey MJ, Lao KSJ, Wong ICK Abstract BACKGROUND: Melatonin is widely available either on prescription for the treatment of sleep disorders or as an over-the-counter dietary supplement. Melatonin has also recently been licensed in the UK for the short-term treatment of jetlag. Little is known...
Analysis of pharmacotherapy regimen and costs in patients with drug-resistant epilepsy following vagus nerve stimulation therapy: a single-center study (Poland). Acta Neurol Belg. 2019 Nov 13;: Authors: Kopciuch D, Barciszewska AM, Fliciński J, Zaprutko T, Kus K, Steinborn B, Nowakowska E Abstract Approximately 30-40% of patients with drug-resistant epilepsy (DRE) who underwent vagus nerve stimulator (VNS) implantation achieve above 50% reduction in...
Assessment of Pregabalin-Induced Cardiotoxicity in Rats: Mechanistic Role of Angiotensin 1-7. Cardiovasc Toxicol. 2019 Nov 12;: Authors: Awwad ZM, El-Ganainy SO, ElMallah AI, Khedr SM, Khattab MM, El-Khatib AS Abstract Pregabalin (PRG) possesses great therapeutic benefits in the treatment of epilepsy, neuropathic pain, and fibromyalgia. However, clinical data have reported incidence or exacerbation of heart failure following PRG administration. Experimental...
Keto microbiota: A powerful contributor to host disease recovery. Rev Endocr Metab Disord. 2019 Nov 13;: Authors: Cabrera-Mulero A, Tinahones A, Bandera B, Moreno-Indias I, Macías-González M, Tinahones FJ Abstract Gut microbiota (GM) is a key contributor to host metabolism and physiology. Data generated on comparing diseased and healthy subjects have reported changes in the GM profile between both health states, suggesting certain bacterial composition...
Transcranial Magnetic Stimulation for the Treatment of Pediatric Neurological Disorders. Curr Treat Options Neurol. 2019 Nov 13;21(11):58 Authors: Malone LA, Sun LR Abstract PURPOSE OF REVIEW: Repetitive transcranial magnetic stimulation (rTMS) is a form of noninvasive brain stimulation that is used for the treatment of migraine and major depression in adults and is now being evaluated for use in other disorders. The purpose of this review is to summarize...
High-frequency oscillations in scalp EEG mirror seizure frequency in pediatric focal epilepsy. Sci Rep. 2019 Nov 12;9(1):16560 Authors: Boran E, Sarnthein J, Krayenbühl N, Ramantani G, Fedele T Abstract High-frequency oscillations (HFO) are promising EEG biomarkers of epileptogenicity. While the evidence supporting their significance derives mainly from invasive recordings, recent studies have extended these observations to HFO recorded in the widely...
Related ArticlesAudio-Tactile and Peripersonal Space Processing Around the Trunk in Human Parietal and Temporal Cortex: An Intracranial EEG Study. Cereb Cortex. 2018 09 01;28(9):3385-3397 Authors: Bernasconi F, Noel JP, Park HD, Faivre N, Seeck M, Spinelli L, Schaller K, Blanke O, Serino A Abstract Interactions with the environment happen within one's peripersonal space (PPS)-the space surrounding the body. Studies in monkeys and humans have highlighted...
Related ArticlesSibling-Controlled Study of Parental Bonding, Coping, and Urgent Health-Care Use in Families With Children With Nonepileptic Seizures. J Pediatr Psychol. 2018 11 01;43(10):1128-1137 Authors: Bursch B, Forgey M, Emerson ND, Siddarth P, Weisbrot DM, Shaw RJ, Doss J, Falcone T, Hinman K, LaFrance WC, Laptook R, Willis MD, Deggelman EL, Caplan R, Plioplys S Abstract Objectives: Pediatric psychogenic nonepileptic seizures (PNES) is a functional...
Related ArticlesSupporting advanced dementia in people with Down syndrome and other intellectual disability: consensus statement of the International Summit on Intellectual Disability and Dementia. J Intellect Disabil Res. 2018 07;62(7):617-624 Authors: McCarron M, McCallion P, Coppus A, Fortea J, Stemp S, Janicki M, Wtachman K Abstract BACKGROUND: The International Summit on Intellectual Disability and Dementia (Glasgow, Scotland; October 2016) noted...
The Use of Medical Cannabis with Other Medications: A Review of Safety and Guidelines - An Update Book. 2019 09 27Authors: MacDonald E, Adams A Abstract According to Statistics Canada’s National Cannabis Survey, approximately 2.7 million Canadians (9%) reported using cannabis for medical reasons in the first half of 2019.1 For the purposes of this report, medical cannabis refers to use of the cannabis plant or its extracts or synthetic cannabinoids for medical purposes....
Does tranexamic acid improve intra-operative visualisation in endoscopic ear surgery? A double-blind, randomised, controlled trial. J Laryngol Otol. 2019 Nov 13;:1-5 Authors: Das A, Mitra S, Ghosh D, Kumar S, Sengupta A Abstract OBJECTIVE: To assess the effect of tranexamic acid on intra-operative bleeding and surgical field visualisation. METHODS: Fifty patients undergoing various endoscopic ear surgical procedures, including endoscopic tympanoplasty,...
Open mesh plug repair for inguinal hernia after femoro-femoral arterial bypass: Two retrospective case series. Int J Surg Case Rep. 2019 Aug 20;65:180-183 Authors: Onda S, Suwa K, Neki K, Yanaga K Abstract INTRODUCTION: Reports on inguinal hernia repair after femoral arterial bypass are limited, and a recommended procedure has not been established. PRESENTATION OF CASE: Case 1. A 77-year-old man who had a history of femoro-femoral arterial bypass...
Obstructive Sleep Apnea in Acromegaly and the Effect of Treatment: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2019 Nov 13;: Authors: Parolin M, Dassie F, Alessio L, Wennberg A, Rossato M, Vettor R, Maffei P, Pagano C Abstract BACKGROUND: Obstructive Sleep Apnea (OSA) is a common disorder characterized by upper airway collapse requiring nocturnal ventilatory assistance. Multiple studies have investigated the relationship between acromegaly...
Polysomnography Utilization in Veterans Presenting Acutely with Ischemic Stroke or Transient Ischemic Attack. Cerebrovasc Dis. 2019 Nov 13;:1-5 Authors: Koo BB, Sico JJ, Myers LJ, Perkins AJ, Levine D, Miech EJ, Damush TM, Rattray N, Homoya B, Ferguson J, Myers J, Zhang Y, Bravata DM Abstract INTRODUCTION: Obstructive sleep apnea (OSA) is an independent cerebrovascular risk factor and highly prevalent in patients with ischemic stroke and transient ischemic...
Is nurse-led telephone follow-up for post-operative obstructive sleep apnoea patients effective? A prospective observational study at a paediatric tertiary centre. Int J Pediatr Otorhinolaryngol. 2019 Nov 05;129:109766 Authors: Walijee H, Sood S, Markey A, Krishnan M, Lee A, De S Abstract OBJECTIVES: To assess the effectiveness and patient satisfaction of a nurse-led telephone follow-up service in children following surgery for sleep disordered breathing...
Computational fluid dynamics simulation of changes in the morphology and airflow dynamics of the upper airways in OSAHS patients after treatment with oral appliances. PLoS One. 2019;14(11):e0219642 Authors: Song B, Li Y, Sun J, Qi Y, Li P, Li Y, Gu Z Abstract OBJECTIVES: To explore the changes of morphology and internal airflow in upper airways (UA) after the use of oral appliances (OAs) in patients with obstructive sleep apnea hypopnea syndrome (OSAHS),...
Clinical Lycanthropy (lycomania) in Neuropsychiatric Patients With Obstructive Sleep Apnea. Prim Care Companion CNS Disord. 2019 Nov 07;21(6): Authors: Marques JG PMID: 31721486 [PubMed - in process]
Obstructive sleep apnea: Do positional patients become nonpositional patients with time? Laryngoscope. 2019 Nov 13;: Authors: Oksenberg A, Goizman V, Eitan E, Nasser K, Gadoth N, Leppänen T Abstract OBJECTIVES: Obstructive sleep apnea (OSA) patients with breathing abnormalities only or mainly in the supine posture are designated positional patients (PPs), whereas nonpositional patients (NPPs) have many breathing abnormalities in both lateral and supine...
Efficacy of Antidepressants in the Treatment of Obstructive Sleep Apnea Compared to Placebo. A Systematic Review with Meta-Analyses. Sleep Breath. 2019 Nov 12;: Authors: AbdelFattah MR, Jung SW, Greenspan MA, Padilla M, Enciso R Abstract PURPOSE: To establish the efficacy of oral antidepressants compared to placebo in improving obstructive sleep apnea (OSA) as measured on a polysomnography study. Secondary outcomes included self-reported sleepiness....
Topical Collection: Sleep apnea syndrome: from the pathogenesis to the last therapies : Special Guest Editors: Manuele Casale, Rinaldi Vittorio. Eur Arch Otorhinolaryngol. 2019 Nov 13;: Authors: PMID: 31720781 [PubMed - as supplied by publisher]
Oral Appliances in Obstructive Sleep Apnea. Healthcare (Basel). 2019 Nov 08;7(4): Authors: Dieltjens M, Vanderveken O Abstract Oral appliance therapy is increasingly prescribed as a non-invasive treatment option for patients diagnosed with obstructive sleep apnea. The custom-made titratable mandibular advancement devices (MAD) are the recommended type of oral appliances. Mandibular advancement devices are efficacious in reducing the severity of obstructive...
Anticancer Activity of Platinum (II) Complex with 2-Benzoylpyridine by Induction of DNA Damage, S-Phase Arrest, and Apoptosis. Anticancer Agents Med Chem. 2019 Nov 11;: Authors: Li YL, Gan XL, Zhu RP, Wang X, Liao DF, Jin J, Huang Z Abstract OBJECTIVE: To overcome the disadvantages of cisplatin, numerous platinum (Pt) complexes have been prepared. However, the anticancer activity and mechanism of Pt(II) complexed with 2-benzoylpyridine [Pt(II)-Bpy]:...
Arsenic Trioxide and Thalidomide Combination Induces Autophagy Along with Apoptosis in Acute Myeloid Cell Lines. Cell J. 2020 Jul;22(2):193-202 Authors: Mohammadi Kian M, Haghi A, Salami M, Chahardouli B, Rostami SH, Malekzadeh K, Kamranzadeh Foumani H, Mohammadi S, Nikbakht M Abstract Objective: Autophagy and apoptosis play key roles in cancer survival and pathogenesis and are governed by specific genes which have a dual role in both cell death and...
Label free, quantitative single-cell fate tracking of time-lapse movies. MethodsX. 2019;6:2468-2475 Authors: Caldon CE, Burgess A Abstract Historically, the ability to perform multi-day time-lapse imaging of adherent cells required expensive and specialized microscopy equipment. As byproduct of this cost, many labs would synchronize cells using inhibitors such as hydroxyurea and thymidine, and or use fluorescent biosensors to minimize time required on...
Checkpoint Regulation of Nuclear Tos4 Defines S Phase Arrest in Fission Yeast. G3 (Bethesda). 2019 Nov 12;: Authors: Kim SM, Tripathi VP, Shen KF, Forsburg SL Abstract From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate cell proliferation and can be monitored by dynamic visual markers in living cells. We have observed S phase progression by monitoring nuclear accumulation of the FHA-containing DNA binding protein...
Diversity of complexes based on p-nitrobenzoylhydrazide, benzoylformic acid and diorganotin halides or oxides self-assemble: Cytotoxicity, the induction of apoptosis in cancer cells and DNA-binding properties. Bioorg Chem. 2019 Nov 04;:103402 Authors: Jiang W, Fan S, Zhou Q, Zhang F, Kuang D, Tan Y Abstract Eight organotin(IV) complexes (C1-C8) have been synthesized and characterized by elemental analysis, fourier transform infrared spectroscopy (FT-IR),...
Acetyl-L-Carnitine downregulates invasion (CXCR4/CXCL12, MMP-9) and angiogenesis (VEGF, CXCL8) pathways in prostate cancer cells: rationale for prevention and interception strategies. J Exp Clin Cancer Res. 2019 Nov 12;38(1):464 Authors: Baci D, Bruno A, Cascini C, Gallazzi M, Mortara L, Sessa F, Pelosi G, Albini A, Noonan DM Abstract BACKGROUND: Prostate cancer (PCa) is a leading cause of cancer-related death in males worldwide. Exacerbated inflammation...
Novel Antrodia cinnamomea Extract Reduced Cancer Stem-Like Phenotype Changes and Resensitized KRAS-Mutant Colorectal Cancer via a MicroRNA-27a Pathway. Cancers (Basel). 2019 Oct 26;11(11): Authors: Lin TJ, Lai KC, Lee AS, Chang CH, Liu CL, Chung CH Abstract Colorectal cancer (CRC) is one of the most common causes of death in Taiwan. Previous studies showed that Antrodia cinnamomea (AC) can treat poisoning, diarrhea, and various types of cancer. Therefore,...
Synergism Through WEE1 and CHK1 Inhibition in Acute Lymphoblastic Leukemia. Cancers (Basel). 2019 Oct 25;11(11): Authors: Ghelli Luserna Di Rorà A, Bocconcelli M, Ferrari A, Terragna C, Bruno S, Imbrogno E, Beeharry N, Robustelli V, Ghetti M, Napolitano R, Chirumbolo G, Marconi G, Papayannidis C, Paolini S, Sartor C, Simonetti G, Yen TJ, Martinelli G Abstract INTRODUCTION: Screening for synthetic lethality markers has demonstrated that the inhibition...
Rational Design and Synthesis of Diverse Pyrimidine Molecules Bearing Sulfonamide Moiety as Novel ERK Inhibitors. Int J Mol Sci. 2019 Nov 08;20(22): Authors: Halawa AH, Eskandrani AA, Elgammal WE, Hassan SM, Hassan AH, Ebrahim HY, Mehany ABM, El-Agrody AM, Okasha RM Abstract Protein kinases orchestrate diverse cellular functions; however, their dysregulation is linked to metabolic dysfunctions, associated with many diseases, including cancer. Mitogen-Activated...
Related ArticlesCuprous oxide nanoparticles reduces hypertrophic scarring by inducing fibroblast apoptosis. Int J Nanomedicine. 2019;14:5989-6000 Authors: Xiao Y, Xu D, Song H, Shu F, Wei P, Yang X, Zhong C, Wang X, Müller WE, Zheng Y, Xiao S, Xia Z Abstract Background: Less apoptosis and excessive growth of fibroblasts contribute to the progression of hypertrophic scar formation. Cuprous oxide nanoparticles (CONPs) could have not only inhibited tumor...
Related ArticlesVaccination With Mitoxantrone-Treated Primary Colon Cancer Cells Enhances Tumor-Infiltrating Lymphocytes and Clinical Responses in Colorectal Liver Metastases. J Surg Res. 2019 01;233:57-64 Authors: Qin J, Kunda NM, Qiao G, Tulla K, Prabhakar BS, Maker AV Abstract BACKGROUND: Colorectal cancer remains a leading cause of cancer-related mortality worldwide. Metastases to the liver are often present at initial presentation and will form...
Related ArticlesDevelopment of a transendothelial shuttle by macrophage modification. J Tissue Eng Regen Med. 2018 04;12(4):e1889-e1898 Authors: Visser JG, Smith C Abstract One of the limiting factors in tissue regeneration, particularly in the context of chronic disease such as myodystrophy, motor neuron disease, sarcopenia, and cardiovascular disease, is limited availability of stem cells. We propose employing autologous macrophages to deliver stem...
Primates got personality, too: Toward an integrative primatology of consistent individual differences in behavior. Evol Anthropol. 2019 Nov 13;: Authors: Blaszczyk MB Abstract In recent years, research on animal personality has exploded within the field of behavioral ecology. Consistent individual differences in behavior exist in a wide range of species, and these differences can have fitness consequences and influence several aspects of a species' ecology....
Clinical impact of data feedback at lung cancer multidisciplinary team meetings: A mixed methods study. Asia Pac J Clin Oncol. 2019 Nov 12;: Authors: Stone E, Rankin NM, Vinod SK, Nagarajah M, Donnelly C, Currow DC, Fong KM, Phillips JL, Shaw T Abstract AIM: Multidisciplinary team (MDT) meetings can facilitate optimal lung cancer care, yet details of structured data collection and feedback remain sparse. This study aimed to investigate data collection...
The aryl hydrocarbon receptor (AhR) as a breast cancer drug target. Med Res Rev. 2019 Nov 12;: Authors: Baker JR, Sakoff JA, McCluskey A Abstract Breast cancer is the most common cancer in women, with more than 1.7 million diagnoses worldwide per annum. Metastatic breast cancer remains incurable, and the presence of triple-negative phenotypes makes targeted treatment impossible. The aryl hydrocarbon receptor (AhR), most commonly associated with the metabolism...
High nodal FDG uptake increases risk of distant metastasis in patients with oropharyngeal squamous cell carcinoma. Eur J Nucl Med Mol Imaging. 2019 Nov 13;: Authors: Jensen JS, Christensen JT, Håkansson K, Zamani M, Vogelius IR, Löfgren J, Fischer BM, Friborg J, von Buchwald C, Rasmussen JH Abstract BACKGROUND: The purpose of this study was to investigate if FDG uptake metrics in primary tumor and lymph node metastases in patients with oropharyngeal...
Increased radiation toxicity with germline ATM variant of uncertain clinical significance. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):672-680 Authors: Mullins BT, Gupta G Abstract Background: While patients with ataxia telangiectasia are known to have increased radiation sensitivity, patients with germline heterozygous ataxia telangiectasia mutated (ATM) mutations can have widely varying functional and clinical effects, which can make management decisions...
A Scoping Review of Physical Therapy Interventions for Childhood Cancers. Physiother Can. 2019;71(3):287-296 Authors: Ospina PA, McNeely ML Abstract Purpose: Children and adolescents undergoing cancer treatment are at high risk of developing serious adverse effects, many of which respond to physical therapy (PT). This scoping review aims to (1) outline the state of the research involving PT for children with cancer and (2) identify gaps in the literature...
Insulin enhancement of the antitumor activity of chemotherapeutic agents in colorectal cancer is linked with downregulating PIK3CA and GRB2. Sci Rep. 2019 Nov 12;9(1):16647 Authors: Agrawal S, Woźniak M, Łuc M, Makuch S, Pielka E, Agrawal AK, Wietrzyk J, Banach J, Gamian A, Pizon M, Ziółkowski P Abstract The present state of cancer chemotherapy is unsatisfactory. New anticancer drugs that marginally improve the survival of patients continue to be developed...
System-based approaches as prognostic tools for glioblastoma. BMC Cancer. 2019 Nov 12;19(1):1092 Authors: Salvucci M, Zakaria Z, Carberry S, Tivnan A, Seifert V, Kögel D, Murphy BM, Prehn JHM Abstract BACKGROUND: The evasion of apoptosis is a hallmark of cancer. Understanding this process holistically and overcoming apoptosis resistance is a goal of many research teams in order to develop better treatment options for cancer patients. Efforts are also...
20 years of rituximab treatment: what have we learnt? Future Oncol. 2019 Nov 13;: Authors: Renner C PMID: 31718346 [PubMed - as supplied by publisher]
Scientific rationale underpinning the development of biosimilar rituximab in hematological cancers and inflammatory diseases. Future Oncol. 2019 Nov 13;: Authors: Jurczak W, Cohen S, Illidge TM, Silva AD, Amersdorffer J Abstract Sandoz rituximab (SDZ-RTX; Rixathon®; GP2013), a rituximab biosimilar, was approved in June 2017 in Europe in all indications of reference rituximab. The stepwise SDZ-RTX development program generated extensive physicochemical,...
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