Paravertebral Muscle Training in Patients with Unstable Spinal Metastases Receiving Palliative Radiotherapy: An Exploratory Randomized Feasibility Trial. Cancers (Basel). 2019 Nov 11;11(11): Authors: Sprave T, Rosenberger F, Verma V, Förster R, Bruckner T, Schlampp I, Bostel T, Welzel T, Akbaba S, Rackwitz T, Nicolay NH, Grosu AL, Wiskemann J, Debus J, Rief H Abstract Background: Isometric paravertebral muscle training (IPMT) may improve mobility, pain,...
Thu Nov 14, 2019 17:09
Circulating Endometrial Cells: A New Source of Information on Endometriosis Dynamics. J Clin Med. 2019 Nov 11;8(11): Authors: Pospisilova E, Kiss I, Souckova H, Tomes P, Spicka J, Matkowski R, Jedryka M, Ferrero S, Bobek V, Kolostova K Abstract The focus of the presented work was to isolate and characterize circulating endometrial cells (CECs) enriched from peripheral blood (PB) of patients with diagnosed endometriosis. The molecular characteristics...
Thu Nov 14, 2019 17:09
Characterization and Potential Applications of Dog Natural Killer Cells in Cancer Immunotherapy. J Clin Med. 2019 Oct 27;8(11): Authors: Gingrich AA, Modiano JF, Canter RJ Abstract Natural killer (NK) cells of the innate immune system are a key focus of research within the field of immuno-oncology based on their ability to recognize and eliminate malignant cells without prior sensitization or priming. However, barriers have arisen in the effective translation...
Thu Nov 14, 2019 17:09
The Role of Nrf2 Activity in Cancer Development and Progression. Cancers (Basel). 2019 Nov 08;11(11): Authors: Zimta AA, Cenariu D, Irimie A, Magdo L, Nabavi SM, Atanasov AG, Berindan-Neagoe I Abstract Nrf2 is a transcription factor that stimulates the expression of genes which have antioxidant response element-like sequences in their promoter. Nrf2 is a cellular protector, and this principle applies to both normal cells and malignant cells. While healthy...
Thu Nov 14, 2019 17:09
Related ArticlesCity Cancer Challenge: Changing the Future of Cancer in Urban Populations. Am Soc Clin Oncol Educ Book. 2019 Jan;39:e121-e125 Authors: Henshall SM, Villar HV, Doria R, Milner DA Abstract Incidence and mortality from cancer is increasing in most countries in the world, with the highest burden in developing countries. City Cancer Challenge (C/Can), an initiative launched in 2017, aims to improve access to quality cancer care in metropolitan...
Thu Nov 14, 2019 17:09
Related ArticlesGermline Genetic Testing for Breast Cancer Risk: The Past, Present, and Future. Am Soc Clin Oncol Educ Book. 2019 Jan;39:61-74 Authors: Yadav S, Couch FJ Abstract The field of germline genetic testing for breast cancer (BC) risk has evolved substantially in the last decade. The introduction of multigene panel testing (MGPT) led to an urgent need to understand the cancer risk associated with several genes included in the panels. Although...
Thu Nov 14, 2019 17:09
Related ArticlesDebating the Optimal Approach to Nodal Management After Pathologic Complete Response to Neoadjuvant Chemotherapy in Patients With Breast Cancer. Am Soc Clin Oncol Educ Book. 2019 Jan;39:42-48 Authors: Carter S, Neuman H, Mamounas EP, Bedrosian I, Moulder S, Montero AJ, Jagsi R Abstract Greater use of neoadjuvant chemotherapy in patients with breast cancer has led surgeons and radiation oncologists to have frequent encounters with women...
Thu Nov 14, 2019 17:09
Related ArticlesMany Shades of Disparities in Myeloma Care. Am Soc Clin Oncol Educ Book. 2019 Jan;39:519-529 Authors: Ganguly S, Mailankody S, Ailawadhi S Abstract Treatment of multiple myeloma (MM) has notably evolved with improved patient outcomes over the past few years. Several new drugs have become available, and large national and international clinical trials have set the stage for evidence-based medicine guidelines for the treatment of patients...
Thu Nov 14, 2019 17:09
Related ArticlesManagement for Different Glioma Subtypes: Are All Low-Grade Gliomas Created Equal? Am Soc Clin Oncol Educ Book. 2019 Jan;39:133-145 Authors: Tom MC, Cahill DP, Buckner JC, Dietrich J, Parsons MW, Yu JS Abstract Following the identification of key molecular alterations that provided superior prognostication and led to the updated 2016 World Health Organization (WHO) Central Nervous System (CNS) Tumor Classification, the understanding of...
Thu Nov 14, 2019 17:09
Related ArticlesThe Future of Wearable Technologies and Remote Monitoring in Health Care. Am Soc Clin Oncol Educ Book. 2019 Jan;39:115-121 Authors: Liao Y, Thompson C, Peterson S, Mandrola J, Beg MS Abstract Mobile technology has become a ubiquitous part of everyday life and is changing the way we offer clinical care and perform clinical research. We have unprecedented access to data for one's self-care as well as for sharing with health care providers....
Thu Nov 14, 2019 17:09
Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model. Sci Rep. 2019 Nov 12;9(1):16578 Authors: Uranbileg B, Ito N, Kurano M, Saigusa D, Saito R, Uruno A, Kano K, Ikeda H, Yamada Y, Sumitani M, Sekiguchi M, Aoki J, Yatomi Y Abstract Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain...
Thu Nov 14, 2019 17:03
A Naso-Orbito-Ethmoid (NOE) Fracture Associated with Bilateral Anterior and Posterior Frontal Sinus Wall Fractures Caused by a Horse Kick-Case Report and Short Literature Review. Medicina (Kaunas). 2019 Nov 09;55(11): Authors: Onișor-Gligor F, Țenț PA, Bran S, Juncar M Abstract Naso-orbito-ethmoid (NOE) fractures associated with anterior and posterior frontal sinus wall fractures are among the most challenging cranio-maxillofacial injuries. These represent...
Thu Nov 14, 2019 17:03
Posterior percutaneous transarticular stand-alone screw instrumentation of C1-C2 with endoscopic assistance: A report of two cases. Neurocirugia (Astur). 2019 Nov 09;: Authors: Lvov I, Grin A, Godkov I, Kordonskiy A, Krylov V Abstract We present two cases of minimally invasive posterior transarticular screw fixation of C1-C2. The points for screw insertion were visualized by endoscopy via the instrumental port. A patient with a type III odontoid fracture...
Thu Nov 14, 2019 16:57
30 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/11/14PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Thu Nov 14, 2019 16:57
Meta-analysis of 308-nm excimer laser therapy for alopecia areata. J Dermatolog Treat. 2019 Nov 12;:1-4 Authors: Gupta AK, Carviel JL Abstract Background: Alopecia areata (AA) is an autoimmune disease that can result in spontaneous hair loss. Currently, there is no US Food and Drug Administration (FDA) approved treatment, however new treatments are being investigated. Excimer laser and excimer lamp treatment have been suggested and have the benefit of...
Thu Nov 14, 2019 16:54
Novel Uses of Radioactive Seeds in Surgical Oncology: A Case Series. Cureus. 2019 Sep 20;11(9):e5706 Authors: Beniey M, Boulva K, Kaviani A, Patocskai E Abstract The localization of nonpalpable axillary metastatic lymph nodes has been achieved using several techniques in the past. Amongst these techniques, the use of radioactive iodine seeds is increasingly spread, and was initially reserved to breast-conserving surgery. Many studies have assessed the...
Thu Nov 14, 2019 16:49
Feasibility of targeting glioblastoma stem cells: From concept to clinical trials. Curr Top Med Chem. 2019 Nov 12;: Authors: Tarasov VV, Svistunov AA, Chubarev VN, Zatsepilova TA, Preferanskaya NG, Stepanova OI, Sokolov AV, Dostdar SA, Minyaeva NN, Neganova ME, Klochkov SG, Mikhaleva LM, Somasundaram SG, Kirkland CE, Aliev G Abstract Glioblastoma is a highly aggressive and invasive brain tumor. Current treatment options do not prolong overall survival...
Thu Nov 14, 2019 16:49
Herbal Medicine of the 21st Century: A Focus on the Chemistry, Pharmacokinetics and Toxicity of Five Widely Advocated Phytotherapies. Curr Top Med Chem. 2019 Nov 12;: Authors: Suroowan S, Mahomoodally MF Abstract BACKGROUND: Widely advocated for their health benefits worldwide, herbal medicine (HM) has evolved into a billion dollar generating industry. Much is known on their wellness, prophylactic and therapeutic benefits for the relief of both minor...
Thu Nov 14, 2019 16:49
In silico insights on Disialoganglioside GD2 : A Potential target for Pediatric Neuroblastoma. Curr Top Med Chem. 2019 Nov 11;: Authors: Limaye A, Sweta J, Mudgal U, Mukherjee S, Sharma S, Hussain T, Nayarisseri A, Singh SK Abstract AIMS: The In silico approach provides a platform for determination and establishing a potential inhibitor against GD2 in Pediatric neuroblastoma. BACKGROUND: Originating from the abnormal growth of neuroblasts, pediatric...
Thu Nov 14, 2019 16:49
Search for potential Inducible Nitric Oxide Synthase inhibitors with favorable ADMET profiles for the therapy of Helicobacter pylori infections. Curr Top Med Chem. 2019 Nov 11;: Authors: Rodrigues RP, Ardisson JS, Ribeiro Gonçalves RC, Oliveira TB, Barreto da Silva V, Kawano DF, Kitagawa RR Abstract BACKGROUND: Helicobacter pylori is a gram-negative bacterium related to chronic gastritis, peptic ulcer and gastric carcinoma. During its infection process,...
Thu Nov 14, 2019 16:49
Ligand-Based Pharmacophore Modeling and Virtual Screening to discover novel CYP1A1 Inhibitors. Curr Top Med Chem. 2019 Nov 11;: Authors: Tahir RA, Hassan F, Kareem A, Iftikhar U, Sehgal SA Abstract BACKGROUND: Cytochrome P450, family 1, subfamily A, polypeptide 1 (CYP1A1) is an imperative enzyme due to its immersion in the biotransformation of a wide range of drugs and other xenobiotics. The involvement in drug metabolism suggests this enzyme an effective...
Thu Nov 14, 2019 16:49
The use of fibrin-based tissue adhesives for breast in reconstructive and plastic surgery. Curr Top Med Chem. 2019 Nov 11;: Authors: Chen K, Sinelnikov MY, Nikolenko VN, Reshetov IV, Cao Y, Li Z, Kochurova EV, Nikolenko SN, Avila-Rodríguez M, Somasundaram SG, Kirkland CE, Aliev G Abstract BACKGROUND: Breast plastic surgery is a rapidly evolving field in medicine. The modern view of surgical trends reflects the desire to minimize complications and introduce...
Thu Nov 14, 2019 16:49
Measurements of volumetric bone mineral density in the mandible do not predict spinal osteoporosis. Dentomaxillofac Radiol. 2019 Nov 13;:20190280 Authors: Guo Z, Du X, Wang L, Li K, Jiao J, Guglielmi G, Zhurakivska K, Lo Muzio L, Blake GM, Cheng X Abstract OBJECTIVE: The objective of this study was to determine whether the trabecular volumetric Bone Mineral Density (vBMD) of the middle, body and angle of the mandible correlates with vBMD of the cervical...
Thu Nov 14, 2019 16:47
Tongue Rehabilitation Device for Dysphagic Patients. Sensors (Basel). 2019 Oct 26;19(21): Authors: Milazzo M, Panepinto A, Sabatini AM, Danti S Abstract Dysphagia refers to difficulty in swallowing often associated with syndromic disorders. In dysphagic patients' rehabilitation, tongue motility is usually treated and monitored via simple exercises, in which the tongue is pushed against a depressor held by the speech therapist in different directions....
Thu Nov 14, 2019 16:46
Relationships of p16 Immunohistochemistry and Other Biomarkers With Diagnoses of Cervical Abnormalities: Implications for LAST Terminology. Arch Pathol Lab Med. 2019 Nov 13;: Authors: Castle PE, Adcock R, Cuzick J, Wentzensen N, Torrez-Martinez NE, Torres SM, Stoler MH, Ronnett BM, Joste NE, Darragh TM, Gravitt PE, Schiffman M, Hunt WC, Kinney WK, Wheeler CM, New Mexico HPV Pap Registry Steering Committee, p16 IHC Study Panel Abstract CONTEXT.—: Lower...
Thu Nov 14, 2019 16:44
Bilateral reversed palmaris longus muscle: a case report and systematic literature review. Surg Radiol Anat. 2019 Nov 12;: Authors: Longhurst G, Stone D, Mahony N Abstract PURPOSE: We present a case of a bilateral reversed palmaris longus muscle and a systematic review of the literature on this anatomical variation. METHODS: Routine dissection of a 90-year-old male cadaver revealed a rare bilateral reversed palmaris longus. This was documented...
Thu Nov 14, 2019 16:42
Long noncoding RNA CASC11 promotes osteosarcoma metastasis by suppressing degradation of snail mRNA [Retraction]. Am J Cancer Res. 2019;9(10):2279 Authors: Abstract [This retracts the article on p. 300 in vol. 9, PMID: 30906630.].PMID: 31720089 [PubMed - in process]
Thu Nov 14, 2019 16:38
Long noncoding RNA GAS5 inhibits metastasis by targeting miR-182/ANGPTL1 in hepatocellular carcinoma [Retraction]. Am J Cancer Res. 2019;9(10):2278 Authors: Abstract [This retracts the article on p. 108 in vol. 9, PMID: 30755815.].PMID: 31720088 [PubMed - in process]
Thu Nov 14, 2019 16:38
KLK11 suppresses cellular proliferation via inhibition of Wnt/β-catenin signaling pathway in esophageal squamous cell carcinoma. Am J Cancer Res. 2019;9(10):2264-2277 Authors: He X, Meng F, Qin L, Liu Z, Zhu X, Yu Z, Zheng Y Abstract Studies have demonstrated that kallikrein-associated peptidase 11 (KLK11) is dysregulated in various cancers. However, the potential roles of KLK11 in esophageal squamous cell carcinoma (ESCC) are still unknown. In our study,...
Thu Nov 14, 2019 16:38
OnclncRNA-626 promotes malignancy of gastric cancer via inactivated the p53 pathway through interacting with SRSF1. Am J Cancer Res. 2019;9(10):2249-2263 Authors: Wu ZH, Liu CC, Zhou YQ, Hu LN, Guo WJ Abstract Gastric cancer (GC) is a serious health problem worldwide. The potential involvement of long noncoding RNAs in GC progression remains largely unexplored. Here, we identified a novel long noncoding RNA referred to as onclncRNA-626 (oncogenic lncRNA...
Thu Nov 14, 2019 16:38
The resistance of esophageal cancer cells to paclitaxel can be reduced by the knockdown of long noncoding RNA DDX11-AS1 through TAF1/TOP2A inhibition. Am J Cancer Res. 2019;9(10):2233-2248 Authors: Zhang S, Jiang H, Xu Z, Jiang Y, She Y, Huang X, Feng S, Chen W, Chen S, Chen Y, Qiu G, Zhong S Abstract Esophageal cancer (EC) is one of the most common malignancies in the world. The currently used chemotherapeutic drug for the treatment of EC is paclitaxel...
Thu Nov 14, 2019 16:38
LY2228820 induces synergistic anti-cancer effects with anti-microtubule chemotherapeutic agents independent of P-glycoprotein in multidrug resistant cancer cells. Am J Cancer Res. 2019;9(10):2216-2232 Authors: Chen R, Qiao Y, Hu W, Cheng Q, Xie H, Zhou L, Xu X, Zheng S, Jiang D Abstract Side-effects and resistance substantially limit the efficacy of chemotherapy. One possible solution to this persistent problem would be co-administration of targeted...
Thu Nov 14, 2019 16:38
Modeling multi-needle injection into solid tumor. Am J Cancer Res. 2019;9(10):2209-2215 Authors: Subbotin V, Fiksel G Abstract The discovery of mechanisms by which the cancer cells avoid the host immune attack (immune checkpoints) as well the capability of the monoclonal antibodies (mAbs) to blockade the checkpoint proteins on cancer and tumor-infiltrating cells (CTLA-4, PD-1, and PD-L1) promised new breakthroughs in the cure of cancer. After these mechanisms...
Thu Nov 14, 2019 16:38
Recruitment of monocytes and epigenetic silencing of intratumoral CYP7B1 primarily contribute to the accumulation of 27-hydroxycholesterol in breast cancer. Am J Cancer Res. 2019;9(10):2194-2208 Authors: Shi SZ, Lee EJ, Lin YJ, Chen L, Zheng HY, He XQ, Peng JY, Noonepalle SK, Shull AY, Pei FC, Deng LB, Tian XL, Deng KY, Shi H, Xin HB Abstract Previous studies showed that intratumoral 27-Hydroxycholesterol (27-HC), a metabolite of cholesterol, promotes...
Thu Nov 14, 2019 16:38
Reversal of obesity-driven aggressiveness of endometrial cancer by metformin. Am J Cancer Res. 2019;9(10):2170-2193 Authors: Guo H, Kong W, Zhang L, Han J, Clark LH, Yin Y, Fang Z, Sun W, Wang J, Gilliam TP, Lee D, Makowski L, Zhou C, Bae-Jump VL Abstract BACKGROUND: Obesity and diabetes are associated with increased risk and worse outcomes for endometrial cancer. Metformin is a widely prescribed generic drug for the treatment of type II diabetes and...
Thu Nov 14, 2019 16:38
Development and validation of a m6A RNA methylation regulators-based signature for predicting the prognosis of head and neck squamous cell carcinoma. Am J Cancer Res. 2019;9(10):2156-2169 Authors: Zhao X, Cui L Abstract Head and neck squamous cell carcinoma (HNSCC) is among the most common types of cancers that threat the public health worldwide. A growing body of evidence has demonstrated that m6A RNA methylation plays a critical role in tumorigenesis....
Thu Nov 14, 2019 16:38
25-HC promotes hepatocellular carcinoma metastasis through up-regulation of TLR4 dependent FABP4. Am J Cancer Res. 2019;9(10):2140-2155 Authors: Wang S, Yao Y, Wang X, Zheng G, Ouyang W, Chen W Abstract Metabolic syndrome is a significant risk factor for the development of hepatocellular carcinoma (HCC). 25-HC (25-hydroxycholesterol) synthesized from cholesterol plays an important role in lipid metabolism. However, the functions and mechanism of 25-HC...
Thu Nov 14, 2019 16:38
p38α/S1P/SREBP2 activation by the SAM-competitive EZH2 inhibitor GSK343 limits its anticancer activity but creates a druggable vulnerability in hepatocellular carcinoma. Am J Cancer Res. 2019;9(10):2120-2139 Authors: Yang PM, Hong YH, Hsu KC, Liu TP Abstract Enhancer of zeste homolog 2 (EZH2) mediates epigenetic gene silencing via tri-methylation of histone H3 lysine 27 (H3K27-me3). Increased expression of EZH2 is frequently detected in various cancers...
Thu Nov 14, 2019 16:38
Mechanism, safety and efficacy of three tyrosine kinase inhibitors lapatinib, neratinib and pyrotinib in HER2-positive breast cancer. Am J Cancer Res. 2019;9(10):2103-2119 Authors: Xuhong JC, Qi XW, Zhang Y, Jiang J Abstract The incidence of breast cancer ranks first among female malignant tumors that affect women's health. Epidermal growth factor receptor (EGFR) family overexpression, especially human epidermal receptor2 (HER2), features prominently...
Thu Nov 14, 2019 16:38
From genomics to functions: preclinical mouse models for understanding oncogenic pathways in prostate cancer. Am J Cancer Res. 2019;9(10):2079-2102 Authors: Yu C, Hu K, Nguyen D, Wang ZA Abstract Next-generation sequencing has revealed numerous genomic alterations that induce aberrant signaling activities in prostate cancer (PCa). Among them are pathways affecting multiple cancer types, including the PI3K/AKT/mTOR, p53, Rb, Ras/Raf/MAPK, Myc, FGF, and...
Thu Nov 14, 2019 16:38
Role of NKG2D and its ligands in cancer immunotherapy. Am J Cancer Res. 2019;9(10):2064-2078 Authors: Liu H, Wang S, Xin J, Wang J, Yao C, Zhang Z Abstract The activating receptor natural killer group 2, member D (NKG2D) is involved in both innate and adaptive immunities, and functions as a "master switch" in determining the activation status of natural killer (NK) cells. NKG2D binds to a diverse family of ligand molecules, which are only expressed at...
Thu Nov 14, 2019 16:38
A Case of Thymic Carcinoma with Bone and Cerebral Metastases Treated with Stereotactic Radiosurgery and Chemotherapy. Am J Case Rep. 2019 Nov 13;20:1669-1674 Authors: Kropf J, Castaneira G, Luc LT, Oriala C, Field Z, Rico A, Carlan SJ Abstract BACKGROUND Thymic carcinoma is a rare malignant neoplasm. High-grade thymic carcinoma has a high recurrence rate following surgery, and a low 5-year survival rate. Approximately 30% of patients with thymic carcinoma...
Thu Nov 14, 2019 16:27
Parathyroidectomy is Safe in Elderly Patients: A National Surgical Quality Improvement Program Study. World J Surg. 2019 Nov 13;: Authors: Khokar AM, Kuchta KM, Moo-Young TA, Winchester DJ, Prinz RA Abstract BACKGROUND: With increasing age, the incidence of hyperparathyroidism is increased. This study evaluates parathyroidectomy outcomes in elderly patients. METHODS: Primary hyperparathyroidism patients having parathyroidectomy as listed in...
Thu Nov 14, 2019 16:25
The Impact of Implementing a Comprehensive Surgical Program on the Surgical Cohort at a Remote Referral Hospital in Southeastern Liberia. World J Surg. 2019 Nov 13;: Authors: Joharifard S, Price N, Ipanaqué JGY, Clarke RH, Nyemah E, Wallace AF, Dobboh C, Howe C, Kortimai LG, Chukwuemeka NS, Mentoe SJ, Kabeto AK, Beste J, Dunbar E Abstract BACKGROUND: Liberia has an extreme health workforce shortage, particularly with respect to surgery. JJ Dossen Memorial...
Thu Nov 14, 2019 16:25
Ability of Laparoscopic Gastric Mobilization to Prevent Pulmonary Complications After Open Thoracotomy or Thoracoscopic Esophagectomy for Esophageal Cancer: A Systematic Review and Meta-analysis. World J Surg. 2019 Nov 13;: Authors: Booka E, Tsubosa Y, Haneda R, Ishii K Abstract BACKGROUND: Esophagectomy has a high risk of postoperative morbidity, and pulmonary complications are the most common causes of serious morbidity. Thoracoscopic esophagectomy...
Thu Nov 14, 2019 16:25
Outcomes After Surgery for Unilateral Dominant Primary Aldosteronism in Sweden. World J Surg. 2019 Nov 11;: Authors: Sellgren F, Koman A, Nordenström E, Hellman P, Hennings J, Muth A Abstract BACKGROUND: Primary aldosteronism (PA) is the most common cause of secondary hypertension. Surgery is the mainstay of treatment for unilateral dominant PA, but reported cure rates varies. The aim of the present study was to investigate contemporary follow-up practices...
Thu Nov 14, 2019 16:25
Incidence and Risk Factors for Severity of Postoperative Ileus After Colorectal Surgery: A Prospective Registry Data Analysis. World J Surg. 2019 Nov 12;: Authors: Venara A, Meillat H, Cotte E, Ouaissi M, Duchalais E, Mor-Martinez C, Wolthuis A, Regimbeau JM, Ostermann S, Hamel JF, Joris J, Slim K, GRACE Collaborative Group For Ileus Study Abstract BACKGROUND: Defining severe postoperative ileus in terms of consequences could help physicians standardize...
Thu Nov 14, 2019 16:25
Welcome New Associate Editor Sanziana Roman of the USA to the World Journal of Surgery. World J Surg. 2019 Nov 12;: Authors: Sosa JA PMID: 31720792 [PubMed - as supplied by publisher]
Thu Nov 14, 2019 16:25
Obstructive Sleep Apnea in Acromegaly and the Effect of Treatment: A Systematic Review and Meta-Analysis. J Clin Endocrinol Metab. 2019 Nov 13;: Authors: Parolin M, Dassie F, Alessio L, Wennberg A, Rossato M, Vettor R, Maffei P, Pagano C Abstract BACKGROUND: Obstructive Sleep Apnea (OSA) is a common disorder characterized by upper airway collapse requiring nocturnal ventilatory assistance. Multiple studies have investigated the relationship between acromegaly...
Thu Nov 14, 2019 16:20
Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS. J Clin Endocrinol Metab. 2019 Nov 13;: Authors: Frederiksen H, Johannsen TH, Andersen SE, Albrethsen J, Landersoe SK, Petersen JH, Andersen AN, Vestergaard ET, Schorring ME, Linneberg A, Main KM, Andersson AM, Juul A Abstract CONTEXT: The lack of sensitive and robust analytical methods has hindered the reliable quantification of estrogen metabolites...
Thu Nov 14, 2019 16:20
Changes over time in Uric Acid in relation to Changes in Insulin Sensitivity, Beta-cell Function, and Glycemia. J Clin Endocrinol Metab. 2019 Nov 13;: Authors: Volpe A, Ye C, Hanley AJ, Connelly PW, Zinman B, Retnakaran R Abstract CONTEXT: Serum uric acid has been linked to risk of type 2 diabetes (T2DM) but debate persists as to whether it plays a causal role. Indeed, it is unclear if changes in uric acid relate to the pathophysiologic determinants...
Thu Nov 14, 2019 16:20
Weight Loss Improves β-Cell Function in People with Severe Obesity and Impaired Fasting Glucose: A Window of Opportunity. J Clin Endocrinol Metab. 2019 Nov 13;: Authors: Rothberg AE, Herman WH, Wu C, IglayReger HB, Horowitz JF, Burant CF, Galecki AT, Halter JB Abstract BACKGROUND: In people with obesity, β-cell function may adapt to insulin resistance. We describe β-cell function in subjects with severe obesity and normal fasting glucose (NFG), impaired...
Thu Nov 14, 2019 16:20
Tumor Volume Useful Beyond Classic Criteria in Selecting Larynx Cancers For Preservation Therapy. Laryngoscope. 2019 Nov 13;: Authors: Sharrett JM, Ward MC, Murray E, Scharpf J, Lamarre ED, Prendes BL, Lorenz RR, Burkey BB, Koyfman SA, Woody NM, Greskovich JF, Adelstein DJ, Geiger JL, Joshi NP Abstract OBJECTIVE: To investigate the association between tumor volume and locoregional failure (LRF) after concurrent chemoradiation (CCRT) for locally advanced...
Thu Nov 14, 2019 16:12
The prognostic value of anterior commissure involvement in T1 glottic cancer: A systematic review and meta-analysis. Laryngoscope. 2019 Nov 13;: Authors: Tulli M, Re M, Bondi S, Ferrante L, Dajko M, Giordano L, Gioacchini FM, Galli A, Bussi M Abstract OBJECTIVE: The anterior commissure is considered a laryngeal subsite, but it is not taken into account in the current T-staging system. The impact of anterior commissure involvement (ACI) on the oncologic...
Thu Nov 14, 2019 16:12
Cough related to swallowing in asthma patients. Asia Pac Allergy. 2019 Oct;9(4):e31 Authors: Kamimura M, Mouri A, Takayama K, Mizutani T, Hamamoto Y, Iikura M, Furihata K Abstract Background: Occurrence of cough during swallowing is common among asthma patients, but has not been investigated in detail. Objective: We conducted an observational study to determine the prevalence of swallowing-related cough (SRC) and its characteristics in asthma...
Thu Nov 14, 2019 16:12
Dose to swallowing structures and dysphagia in head and neck Intensity Modulated Radiation Therapy - A long term prospective analysis. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):654-659 Authors: Kannan RA, Arul Ponni TR Abstract Aim: To analyse the long term swallowing function in head and neck cancer patients and correlate with the dose to midline swallowing structures. Background: The use of concurrent chemo radiation (CRT) as the present...
Thu Nov 14, 2019 16:12
Related ArticlesPathophysiology of Fibrosis in the Vocal Fold: Current Research, Future Treatment Strategies, and Obstacles to Restoring Vocal Fold Pliability. Int J Mol Sci. 2019 May 24;20(10): Authors: Kumai Y Abstract Communication by voice depends on symmetrical vibrations within the vocal folds (VFs) and is indispensable for various occupations. VF scarring is one of the main reasons for permanent dysphonia and results from injury to the unique...
Thu Nov 14, 2019 16:12
Related ArticlesLethal manifestations of angioedema. Forensic Sci Med Pathol. 2019 Sep;15(3):494-497 Authors: Gilbert JD, Byard RW Abstract An 86-year-old woman with a history of angioedema was found dead at her home address. She had recently complained of a swollen tongue. At autopsy the tongue was grossly edematous, protruding from the mouth. There was also marked edema of the tonsillar fossae, epiglottis and glottic inlet, causing critical obstruction....
Thu Nov 14, 2019 16:12
Related ArticlesChanges in airway dimensions after robot assisted surgeries in steep Trendelenburg position. J Robot Surg. 2019 Jun;13(3):463-468 Authors: Reddy S, Jain D, Jain K, Gandhi K, Mohan R, Kang M Abstract Robotic surgeries in the extreme Trendelenburg position can lead to changes in the airway dimensions. We conducted a prospective, observational trial to explore the use of ultrasound to quantify these changes in the airway dimensions and identify...
Thu Nov 14, 2019 16:12
Related ArticlesLost and Found: The Story of a Laryngoscope Bulb. AANA J. 2018 Jun;86(3):73-74 Authors: Manohar N, Fultambkar G, Bandishte S, Shankar Rao K, Srinivas D PMID: 31580816 [PubMed - indexed for MEDLINE]
Thu Nov 14, 2019 16:12
Preparation of a nanovaccine against Brucella melitensis M16 based on PLGA nanoparticles and oligopolysaccharide antigen. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):4248-4256 Authors: Maleki M, Salouti M, Shafiee Ardestani M, Talebzadeh A Abstract Brucellosis is one of the most common and important diseases between humans and animals. Herein, we developed a nanovaccine against Brucella melitensis based on oligopolysaccharide (OPS) antigen and PLGA...
Thu Nov 14, 2019 16:12
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