Brooks DM, Brooks LJ. Reevaluating norms for childhood obstructive sleep apnea. J Clin Sleep Med. 2019;15(11):1557–1558.
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Morse AM, Kothare SV. Seeking the cause of restless legs syndrome in chronic kidney disease. J Clin Sleep Med. 2019;15(11):1559–1560.
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Study Objectives:Previous studies suggest the presence of familial aggregation of obstructive sleep apnea (OSA) in adults. However, similar data on childhood OSA are limited. This family study aimed to investigate the heritability and familial aggregation of childhood OSA and to examine whether significant differences existed between patients of normal weight and overweight.Methods:Children aged 6 to 18 years were recruited as probands either from attendants to sleep clinic (with habitual snoring)...
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Study Objectives:Decreased upper-airway muscle responsiveness is one of the major phenotypes of obstructive sleep apnea. Use of α1-adrenergic antagonists is correlated with decreased muscle responsiveness in animal studies, but this association has not yet been demonstrated in humans. This study examined whether use of α1-adrenergic antagonists is an independent risk factor for sleep apnea in humans.Methods:Data for this retrospective cohort study were obtained from the National Health Insurance...
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Study Objectives:In view of the risk that surgical repair of cleft palate may induce or worsen obstructive sleep apnea (OSA), the goal of this study was to assess presurgical and postsurgical polysomnography (PSG) results for children who underwent primary palatoplasty.Methods:Retrospective case-control series for children with cleft palate repair performed between January 2008 and December 2016 at a tertiary pediatric center. Children underwent PSG before and after surgery.Results:Sixty-four children...
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Study Objectives:Short sleep duration contributes to hypertension, yet few behavioral sleep extension interventions have been developed. The goal of our study was to evaluate the feasibility and preliminary efficacy of a technology assisted sleep extension intervention among individuals with prehypertension/stage 1 hypertension on sleep, blood pressure and patient reported outcomes.Methods:Adults aged 30–65 with 24h ambulatory blood pressure (ABP) > 120/80 mmHg and average weekday sleep duration...
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Study Objectives:Home sleep apnea testing (HSAT) is an efficient and cost-effective method of diagnosing obstructive sleep apnea (OSA). However, nondiagnostic HSAT necessitates additional tests that erode these benefits, delaying diagnoses and increasing costs. Our objective was to optimize this diagnostic pathway by using predictive modeling to identify patients who should be referred directly to polysomnography (PSG) due to their high probability of nondiagnostic HSAT.Methods:HSAT performed as...
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Study Objectives:Continuous positive airway pressure (CPAP) has been increasingly used in children with obstructive sleep apnea (OSA), though it is unclear whether it can ever be ceased. We describe the clinical, demographic, and polysomnographic (PSG) characteristics of a cohort of children with OSA who were successfully weaned off CPAP.Methods:From a pediatric cohort on CPAP for OSA at the Queensland Children’s Hospital between January 2016 and December 2017, a subgroup of children who were taken...
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Study Objectives:Drowsy driving related to obstructive sleep apnea (OSA) represents an important public health problem with limited data on the effect of positive airway pressure (PAP) therapy. We hypothesize that PAP therapy will reduce self-reported drowsy driving in a large clinic-based OSA cohort.Methods:Drowsy driving (self-reported near-accidents/accidents) incidents from baseline to after PAP therapy (stratified by adherence) were compared in a cohort of 2,059 patients with OSA who initiated...
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Study Objectives:The aim of this study was to investigate the association of bedtime with the prevalence of diabetes mellitus (DM) based on a large community-based population.Methods:In total, 5,420 participants (2,574 males and 2,846 females; aged 63.5 ± 11.0 years) from the Sleep Heart Health Study database were selected in this study. Sleep habit was recorded based on a questionnaire administered to patients upon recruitment. Bedtime was categorized as 11:00 pm and before, 11:00 pm to 12:00 am,...
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Study Objectives:Restless legs syndrome (RLS) is increased in pediatric chronic kidney disease (CKD). In adults without CKD, central nervous system iron deficiency is involved in RLS pathogenesis and a low serum ferritin levels is consequently an indication for initiation of iron therapy. However, children with CKD are at risk for iron deficiency and inflammation, which raises serum ferritin. We examined the role of iron deficiency and inflammation in RLS in pediatric CKD.Methods:This cross-sectional...
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Study Objectives:Sexual minority adolescents experience mental and physical health disparities attributable to increased discrimination and minority stress. These same factors may also impair sleep health, although available literature on this topic is limited. This study examined longitudinal associations between adolescent sexual minority status and seven sleep behaviors in young adulthood and tested depressive symptoms and overweight as mediators.Method:Data were drawn from Waves 2 (11th grade)...
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Study Objectives:Consumer wearable devices may be a helpful method of assessing sleep, but validation is required for their use in clinical practice. Our aim was to validate two models of Fitbit sleep trackers that rely on both accelerometer and heart rate sensors against polysomnography in participants with obstructive sleep apnea (OSA).Methods:Participants were adults presenting with symptoms of OSA and attending our outpatient sleep clinic. A polysomnography (PSG) was applied to all participants...
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Study Objectives:Comparable health effects of mandibular advancement device (MAD) and continuous positive airway pressure (CPAP) therapy have been attributed to higher adherence with MAD compared with CPAP therapy. The objective of this study was to make a direct comparison of the objective adherence between MAD and CPAP in patients with moderate obstructive sleep apnea (OSA).Methods:Adherence was monitored for 12 months in 59 patients with moderate OSA (apnea-hypopnea index 15–30 events/h) as part...
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Study Objectives:Scleroderma is associated with abnormal skin thickening, interstitial lung disease, pulmonary hypertension, and abnormalities of the upper airway. These changes can cause cardiopulmonary complications, potentially including sleep-disordered breathing. The objective of this study is to examine the risk of sleep-disordered breathing in patients with scleroderma.Methods:We retrospectively identified patients with documented scleroderma. We abstracted data from their electronic health...
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There is a complex relationship among opioids, sleep and daytime function. Patients and medical providers should be aware that chronic opioid therapy can alter sleep architecture and sleep quality as well as contribute to daytime sleepiness. It is also important for medical providers to be cognizant of other adverse effects of chronic opioid use including the impact on respiratory function during sleep. Opioids are associated with several types of sleep-disordered breathing, including sleep-related...
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Study Objectives:Actigraphy, the tool of choice for assessment of sleep phase disorders, is insensitive to movement-free waking. This study aimed to determine whether the detection of waking could be performed by recording instrumental responses to haptic stimuli delivered by a low-cost device.Methods:Twenty adults underwent 2 nights of laboratory polysomnography (PSG) while wearing a fingerless glove under which a stimulating actigraph (“Wakemeter”) was apposed to the palm. The Wakemeter, controlled...
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Somnambulism is a non-rapid eye movement sleep parasomnia with potential for significant injury as well as functional nighttime and daytime impairment. Clonazepam is frequently used as first line pharmacotherapy. However, the optimal treatment of somnambulism has not been established. In this article, we present the cases of two patients with severe somnambulism who showed a significant therapeutic response to osmotic release oral system methylphenidate (OROS-MPH). In addition to its practical therapeutic...
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Cataplectic facies is an unusual feature described in children with narcolepsy and cataplexy. The typical manifestations of cataplectic facies consist of repetitive mouth opening, tongue protrusion, and ptosis. An interesting observation is that the usual emotional triggers associated with cataplexy such as laughter and joking are not always present, thus hampering diagnosis of the underlying syndrome. Cataplectic facies is thought to be a phenomenon observed in the early stages of narcolepsy type...
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Chada A, Dholakia S, Rye D. A sleepy patient with frequent falls. J Clin Sleep Med. 2019;15(11):1691–1693.
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Voulgaris A, Nena E, Steiropoulos P. Burden of nocturnal hypoxia and type of positive airway pressure therapy may influence markers of acute kidney injury in patients with obstructive sleep apnea. J Clin Sleep Med. 2019;15(11):1695.
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Chuang L-P, Lin S-W, Chen N-H. Author response. J Clin Sleep Med. 2019;15(11):1697–1698.
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Ingram DG, Al-Shawwa B. Serum ferritin in the pediatric sleep clinic: what’s normal anyway? J Clin Sleep Med. 2019;15(11):1699–1700.
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Barnes T, Rosen GM. Understanding the questions parents are asking. J Clin Sleep Med. 2019;15(11):1701.
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Xerfan EMS, Facina AS, Andersen ML, Tufik S, Tomimori J. Hashimoto thyroiditis as a cause or consequence of obstructive sleep apnea. J Clin Sleep Med. 2019;15(11):1703.
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Benbir Senel G, Karadeniz D. Every patient with acute ischemic stroke should be screened for sleep-disordered breathing. J Clin Sleep Med. 2019;15(11):1705–1706.
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Hunasikatti M. Non-contact sensors: need for optimum information is more important than convenience. J Clin Sleep Med. 2019;15(11):1707.
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Schade MM, Montgomery-Downs HE. Utility encompasses both clinical translation and ecologic validity. J Clin Sleep Med. 2019;15(11):1709.
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Sleep disorders are prevalent in patients with end-stage renal disease (ESRD). In those patients on nocturnal dialysis, it is important to perform objective sleep assessment during regular dialysis. We present the case of a man on continuous cycler peritoneal dialysis with disabling fatigue and moderate restless legs syndrome (RLS). Actigraphy demonstrated excessive nocturnal movement. Unattended home polysomnography, performed during his regular peritoneal dialysis, confirmed frequent nocturnal...
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Abstract Background The presence of obstructive sleep apnea (OSA), a novel cardiovascular risk factor, contributes to the development of peripheral arterial diseases (PAD). There is a lack of data showing how often these diseases coexist. Aims The aim of the study was to determine the prevalence of OSA in the population of patients with PAD. ...
Thu Nov 14, 2019 02:00
Publication date: Available online 14 November 2019Source: Sleep MedicineAuthor(s): M.M. Van Veen, F. Rutters, M. Spreen, M. LancelAbstractObjectiveIn forensic psychiatric patients, sleep problems as well as impulsivity and aggression are highly prevalent, but studies on their association over time are lacking. This study investigates the association between sleep quality and changes in impulsivity and aggression in forensic psychiatric patients over one year.MethodsData were drawn from an ongoing...
Thu Nov 14, 2019 18:54
Publication date: Available online 14 November 2019Source: Sleep MedicineAuthor(s): Baran Balcan, Erik Thunström, Tülay Yucel-Lindberg, Kristin Lindberg, Pinar Ay, Yüksel PekerAbstractBackgroundIncreased leptin and decreased adiponectin levels are reported in coronary artery disease (CAD) as well as in obstructive sleep apnoea (OSA). Less is known regarding the impact of continuous positive airway pressure (CPAP) on these biomarkers. We aimed to determine variables associated with leptin and adiponectin...
Thu Nov 14, 2019 18:54
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