Δευτέρα 11 Νοεμβρίου 2019


ASO Author Reflections: Delays in the Treatment of DCIS—What are the Costs?
Latest Results
Mon Nov 11, 2019 02:00
ASO Author Reflections: Use of Machine Learning to Identify Patients with Intrahepatic Cholangiocarcinoma Who Could Benefit More from Neoadjuvant Therapies
Latest Results
Mon Nov 11, 2019 02:00
ASO Author Reflections: Genetic and Immunohistochemical Studies Investigating the Histogenesis of Neuroendocrine and Carcinomatous Components of Combined Neuroendocrine Carcinoma
Latest Results
Mon Nov 11, 2019 02:00
Time to Surgery and the Impact of Delay in the Non-Neoadjuvant Setting on Triple-Negative Breast Cancers and Other Phenotypes
Abstract Background Characterization of breast cancer phenotypes has improved our ability to predict breast cancer behavior. Triple-negative (TN) breast cancers have higher and earlier rates of distant events. It has been suggested that this behavior necessitates treating TNs faster than others, including use of neoadjuvant chemotherapy (NACT) if time to surgery is not rapid. ...
Latest Results
Mon Nov 11, 2019 02:00
A New Patient with Inherited TYK2 Deficiency
Latest Results
Mon Nov 11, 2019 02:00
Pseudomonas jilinensis sp. nov., Isolated from Oil Production Water of Jilin Oilfield in China
Abstract A Gram-stain-negative, rod-shaped bacterial strain JS15-10A1T was isolated from oil production water. Its optimum growth was observed at 37 °C, pH 7.0, and 3% (w/v) NaCl. The 16S rRNA gene sequence of strain JS15-10A1T showed the highest similarities with Pseudomonas parafulva CB-1T (97.6%) and P. fulva IAM 1529T (97.5%). In addition, phylogenetic analyses based on multilocus sequence analyses with concatenating 16S rRNA, gyrB, rpoD, and rpoB genes indicated that strain...
Latest Results
Mon Nov 11, 2019 02:00
Anomalous insertion of the pectoralis minor tendon at the greater tuberosity
Abstract We present a case of ectopic insertion of the whole tendon of the pectoralis minor muscle associated with impingement syndrome. Based on this case, we performed a review of the literature focused on the association between this ectopic tendon insertion and anterior shoulder pain.
Latest Results
Mon Nov 11, 2019 02:00
Efficacy and safety of bosutinib in chronic phase CML patients developing pleural effusion under dasatinib therapy
Latest Results
Fri Nov 01, 2019 02:00
Characteristics and course of patients with advanced hematologic malignancies receiving specialized inpatient palliative care at a German university hospital
Latest Results
Fri Nov 01, 2019 02:00
Growth and physiological response of spinach to various lithium concentrations in soil
Abstract Lithium (Li) exploitation for industrial and domestic use is resulting in a buildup of the element in various environmental components that results in potential toxicity to living systems. Therefore, a soil culture experiment was conducted to evaluate the effects of increasing concentration of Li (0, 20, 40, 60, and 80 mg kg−1 soil) on spinach growth, the effects of Li uptake, and its effects on various physiological attributes of the crop. The results showed that lower...
Latest Results
02:00
Fixed bed biosorption of silver and investigation of functional groups on acidified biosorbent from algae biomass
Abstract This work investigated the use of acidified dealginated residue from Sargassum filipendula algae for biosorption of silver in fixed bed column. This biosorbent was esterified for carboxyl and sulfonate groups to investigate the influence of these groups on silver removal percentage. Potentiometric titration was also evaluated on acidified and esterified biosorbents. Porosity and specific weight were determined by helium picnometry and mercury porosimetry techniques. The...
Latest Results
02:00
Water-level alterations modified nitrogen cycling across sediment-water interface in the Three Gorges Reservoir
Abstract Water-level regime alteration-associated redox fluctuation plays a primary role in governing exchange and transformation of nitrogen (N) in water-level fluctuation zones (WLFZs), while few understanding of how hydrological regimes under reservoir operation affected N cycling across the sediment-water interface (SWI), giving rise to uncertainties in reservoir N nutrient management. Batch microcosm simulation experiments with intact sediment cores from WLFZs of the Three...
Latest Results
02:00
Natural and anthropogenic radionuclides in urban soil around non-nuclear industries (Northern Al Jubail), Saudi Arabia: assessment of health risk
Abstract The residential areas are located around one of the oldest and largest non-nuclear industrial cities in Saudi Arabia, Arabian Gulf. Therefore, it is important to study the radioactivity levels in the urban soil in order to estimate the potential risk of radiation in environment and for public. The activity concentrations of 226Ra, 232Th, 40K, and 137Cs in urban soil around non-nuclear industries were measured using gamma ray spectrometric technique. The mean values of...
Latest Results
Mon Nov 11, 2019 02:00
Fast and sensitive detection of acrolein in environmental water samples without derivatization using liquid chromatography tandem mass spectrometry
Abstract A fast and sensitive SPE-LC-MS/MS method for the determination of acrolein in environmental water samples using activated charcoal as SPE adsorbent was developed. The novelty of this study consists in acrolein extraction, separation and detection without the need of a derivatization process. Physicochemical properties of acrolein, such as low molecular weight and high polarity represent real challenges for extraction, separation, and detection of this pollutant using SPE-LC-MS/MS....
Latest Results
Mon Nov 11, 2019 02:00
Adsorptive removal of antibiotics from water over natural and modified adsorbents
Abstract Various adsorbents including agricultural waste–based adsorbents, nanomaterials and layered double hydroxides have been reviewed for removal of antibiotics from water due to their unique properties. The adsorption mechanism is governed mostly by the affinity of a pollutant to adsorbent materials. However, the main adsorption mechanisms defined in this study for removal of antibiotics are the electrostatic attraction, π–π interaction and hydrogen bonding. The study highlighted...
Latest Results
Mon Nov 11, 2019 02:00
Adsorption of CO 2 on amine-functionalized green metal-organic framework: an interaction between amine and CO 2 molecules
Abstract The efficient capture of CO2 is a critical problem for porous adsorbents. The inadequacy of conventional adsorbents has low adsorption capacity towards CO2 removal. Metal organic frame work has been considered as very effective for CO2 adsorption as it shows higher rate of CO2 adsorption at room temperature. In conventional amine processes, a comparatively high energy penalty is required, whereas a novel class of metal-organic framework by the combination of amine solvent...
Latest Results
Mon Nov 11, 2019 02:00
Application of Systems Thinking to the assessment of an institutional development project of river restoration at a campus university in Southern Brazil
Abstract Rapid urban growth and high population density have become a problem for urban water resources, especially in developing countries. In general, the pollution of rivers and degradation of ecosystems are the result of both management failures and lack of sewage treatment. River restoration appears as a solution to improve this scenario, but it is common for there to be an absence of a systemic vision in these projects. Thus, this work analysed one of these projects as an...
Latest Results
Mon Nov 11, 2019 02:00
Ensemble streamflow projections for a small watershed with HSPF model
Abstract A watershed modeling tool, Hydrological Simulation Program-FORTRAN (HSPF), was utilized to model the hydrological processes in the agricultural Sarısu watershed in western Turkey. The meteorological input data were statistically downscaled time series from General Circulation Model simulations. The input data were constructed as an ensemble of 400 individual time series of temperature, precipitation, dewpoint temperature, solar radiation, potential evapotranspiration,...
Latest Results
Mon Nov 11, 2019 02:00
Nitrate removal performance and diversity of active denitrifying bacteria in denitrification reactors using poly( L -lactic acid) with enhanced chemical hydrolyzability
Abstract Poly(L-lactic acid) (PLLA) can be used as an external electron donor in denitrification reactors to treat drinking water, aquaculture water, and industrial wastewater with an imbalanced carbon/nitrogen ratio. However, for PLLA to function in these applications, its chemical hydrolyzability requires improvement. Although the adjustment of the crystallinity (Xc) is effective in improving the hydrolyzability of PLLA, the condition for the Xc of PLLA, in which a sufficient...
Latest Results
Mon Nov 11, 2019 02:00
Dynamic linkages among CO 2 emissions, human development, financial development, and globalization: empirical evidence based on PMG long-run panel estimation
Abstract This study investigates the impact of the human capital index, globalization, and financial development on carbon dioxide of grouping OECD countries using pool mean group estimation technique from 1990 to 2015. This study also applies the second-generation cross-sectional augmented Dickey-Fuller and cross-sectional Im, Pesaran, Shin panel (CIPS) unit root, and the latest (Westerlund 2008) cointegration tests for further investigations. The result shows that both the human...
Latest Results
Mon Nov 11, 2019 02:00
Kombination von Lomustin und Temozolomid in der Therapie von Patienten mit neu diagnostizierten MGMT-Promotor-methylierten Glioblastomen
Latest Results
Mon Nov 11, 2019 02:00
Notfälle unter medikamentöser Tumortherapie
Zusammenfassung Onkologische Notfälle sind in der Ätiologie und Symptomatik vielfältig und treten häufig mit der Einleitung einer Chemotherapie auf, können sich aber auch während oder mit zeitlicher Verzögerung manifestieren. Die Kenntnis onkologischer Notfälle unter medikamentöser Tumortherapie ist daher nicht nur für die behandelnden Fachdisziplinen wichtig, sondern auch für mit- oder weiterbetreuende Kollegen. Jeder dieser Krankheitszustände erfordert eine sorgfältige Beurteilung...
Latest Results
Mon Nov 11, 2019 02:00
All’s well? Comparing on- and off-site pollen samples and exploring the potential of pollen from man-made contexts
Abstract Pollen analysis has long been used as a tool to make an assessment of regional vegetation. On-site pollen samples are taken for the same purpose at some excavations, because they are often the only available contexts with good preservation conditions. This paper shows that the analysis of on- and off-site pollen samples from the same region (West Frisia, the Netherlands) and time period (Dutch Bronze Age; ca. 2000–800 bc) can give very conflicting results on the type and...
Latest Results
Mon Nov 11, 2019 02:00
Acknowledgment
Latest Results
Mon Nov 11, 2019 02:00
Extranodale Manifestation klassischer Hodgkin-Lymphome im HNO-Bereich
Zusammenfassung Hintergrund Im Kopf-Hals-Bereich kommen auch extranodale Lymphome vor. Diese machen 12–15 % aller malignen Kopf-Hals-Tumoren aus. In seltenen Fällen treten klassische Hodgkin-Lymphome (cHL) auf. Im Waldeyer-Rachenring ist das cHL mit einem Anteil von 1 % aller dort auftretenden Lymphome selten. Im Referenzzentrum für Lymphknotenpathologie des Pathologischen Instituts der Universität Würzburg diagnostizierte Fälle wurden...
Latest Results
Mon Nov 11, 2019 02:00
Hospitalisierung von Kindern nach HNO-Eingriffen in Deutschland
Zusammenfassung Hintergrund Die Morbidität nach Eingriffen an den Tonsillen wird weitgehend durch Schmerzen, die dadurch bedingt verzögerte Nahrungsaufnahme sowie Blutungskomplikationen bestimmt. Die postoperative Unterbringung von Kindern ist Gegenstand von Diskussionen, genauere Informationen zur Situation in Deutschland liegen nicht vor. Material und Methode ...
Latest Results
Mon Nov 11, 2019 02:00
Aktive Hörimplantate bei chronischer Otitis media
Zusammenfassung Bei Patienten mit unzureichender Hörverbesserung nach Tympanoplastik können aktive Hörimplantate eine Hörrehabilitation bei frustraner Hörgeräteversorgung ermöglichen, in dem sie im Sinne eines vibromechanischen Bypasses die Steifigkeit und Dämpfung eines schlecht schwingenden Trommelfells bzw. einer (rekonstruierten) Gehörknöchelchenkette umgehen. Die Auswahl des Hörsystems ist dabei abhängig vom maximalen Ausgangspegel des Hörsystems sowie den anatomischen Voraussetzungen...
Latest Results
Mon Nov 11, 2019 02:00
Wurster Fluidised Bed Coating of Microparticles: Towards Scalable Production of Oral Sustained-Release Liquid Medicines for Patients with Swallowing Difficulties
Abstract Suspension of microparticles in an easy-to-swallow liquid is one approach to develop sustained-release formulations for children and patients with swallowing difficulties. However, to date production of sustained-release microparticles at the industrial scale has proven to be challenging. The aim of this investigation was to develop an innovative concept in coating sustained-release microparticles using industrial scalable Wurster fluidised bed to produce oral liquid...
Latest Results for AAPS PharmSciTech
Mon Nov 11, 2019 02:00
Mechanical Characterization of Thermally Annealed Tablets Containing Polyethylene Oxide for Abuse Deterrence
Abstract The abuse of prescription opioid drugs is a well-documented and very serious problem. One of the typical first steps an abuser will take is to manipulate a tablet into to a fine powder. To deter this behavior, formulators use crush-resistant technologies like polyethylene oxide (PEO). When heat-treated, PEO creates a hard, flexible tablet that cannot be easily ground down into a fine powder. We investigated the effects of PEO molecular weight (MW), annealing temperature,...
Latest Results for AAPS PharmSciTech
Mon Nov 11, 2019 02:00
Formulation of Direct Compression Zidovudine Tablets to Correlate the SeDeM Diagram Expert System and the Rotary Press Simulator Styl’ONE Results
Abstract The SeDeM diagram expert system has been applied to study Zidovudine and some excipients. From the obtained diagrams, a pharmaceutical formula has been designed. SeDeM diagram ascertains the critical parameters that are suitable for a direct compression. The formula is compressed using a rotary tablet press simulator which emulates rotary tablet press’ compression profiles. From these compressions, we study the formula behavior under different industrial production conditions...
Latest Results for AAPS PharmSciTech
Mon Nov 11, 2019 02:00
Icicle sign: autoimmune pancreatitis
Latest Results for Abdominal Imaging
Mon Nov 11, 2019 02:00
Imaging guidelines for acute pancreatitis: when and when not to image
Abstract In patients with acute pancreatitis (AP), diagnostic imaging is performed for various reasons, including the detection of the etiology (e.g., biliary obstruction caused by gallstones), diagnosis of pancreatitis in an unclear clinical setting, assessment of the severity of the process, and evaluation of its complications. In spite of the potential benefits of these imaging studies in the setting of AP, especially economic consequences but also medical risks are associated...
Latest Results for Abdominal Imaging
Mon Nov 11, 2019 02:00
The cloud sign of mass-forming intrahepatic cholangiocarcinoma
Latest Results for Abdominal Imaging
Mon Nov 11, 2019 02:00
Flow-regulated versus differential pressure valves for idiopathic normal pressure hydrocephalus: comparison of overdrainage rates and neurological outcome
Abstract Background To compare flow-regulated (FR) and differential pressure (DP) valves for treatment of patients with idiopathic normal hydrocephalus (iNPH) focusing on overdrainage and neurological outcome. Methods This is a retrospective study of patients with iNPH treated with FR and DP valves at a single institution between 2008 and 2018. The neurological...
Latest Results for Acta Neurochirurgica
02:00
Spontaneous regression of a clival chordoma. Case report
Abstract In this case report, we present a rare and previously unreported case of spontaneous regression of a histologically consistent clival chordoma. At the time of diagnosis, imaging demonstrated a T2 hyperintense and T1 isointense midline skull base mass, centered in the nasopharynx, with scalloping of the ventral clivus consistent with a chordoma measuring 3.1 × 1.9 × 3.0 cm (8.84 cm3). On pre-operative imaging 2 months later, with no intervening therapy, the mass had regressed...
Latest Results for Acta Neurochirurgica
02:00
Lower subscapular nerve transfer for axillary nerve repair in upper brachial plexus palsy
Abstract Background The potential to utilize the lower subscapular nerve for brachial plexus surgery has been suggested in many anatomical studies. However, we know of no studies in the literature describing the use of the lower subscapular nerve for axillary nerve reconstruction to date. This study aimed to examine the effectiveness of this nerve transfer in patients with upper brachial plexus palsy. ...
Latest Results for Acta Neurochirurgica
02:00
X-ray exposure in odontoid screwing for Anderson type II fracture: comparison between O-arm and C-arm-assisted procedures
Abstract Background Since the odontoid fractures become increasingly common in the aging population, technical improvements are even more needed. The odontoid screwing has been progressively preferred by many surgeons in type II fractures according to the Anderson-D’Alonzo classification system. However, X-ray exposure remains an issue for surgeons and OR staff members. The aim of the present study was to investigate the feasibility of...
Latest Results for Acta Neurochirurgica
02:00
Ross C. Puffer: Neurosurgery primary board review
Latest Results for Acta Neurochirurgica
02:00

Case Series of Combined XEN Implantation and Phacoemulsification in Chinese Eyes: One-Year Outcomes
Abstract Purpose The outcome of XEN implantation in Chinese eyes has not been previously reported. The purpose of our study is to evaluate the efficacy and safety of combined cataract surgery and XEN implantation in Chinese eyes with glaucoma. Methods We conducted a prospective study of 31 consecutive Chinese patients who underwent combined...
Latest Results for Advances in T...
00:43
Tocilizumab Effects on Coagulation Factor XIII in Patients with Rheumatoid Arthritis
Abstract Introduction Rheumatoid arthritis (RA) is a chronic systemic auto-immune disease associated with a prothrombotic state. Tocilizumab, an interleukin-6 receptor inhibitor, is highly effective in controlling disease activity and thrombotic risk. Factor XIII (FXIII), involved in thrombotic complications, has been reported to be reduced in RA patients during maintenance treatment with tocilizumab, but no data are available before...
Latest Results for Advances in T...
00:43
Comparison of Excimer Laser Versus Femtosecond Laser Assisted Trephination in Penetrating Keratoplasty: A Retrospective Study
Abstract Introduction To compare the impact of non-mechanical excimer-assisted (EXCIMER) and femtosecond laser-assisted (FEMTO) trephination on outcomes after penetrating keratoplasty (PK). Methods In this retrospective study, 68 eyes from 23 females and 45 males (mean age at time of surgery, 53.3 ± 19.8 years) were included. Inclusion criteria...
Latest Results for Advances in T...
00:43
Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients
Abstract The current recommendations for the treatment of chronic obstructive pulmonary disease (COPD) are pushing towards triple combination therapy based on the combination of an inhaled corticosteroid (ICS) associated with two bronchodilator agents. However, dual bronchodilation remains the cornerstone for the treatment of most COPD patients. Combining a long-acting β2 adrenoceptor agonist (LABA) with a long-acting muscarinic antagonist (LAMA) induces appreciable synergistic...
Latest Results for Advances in T...
00:43
Evaluation of the Cost Per Patient Achieving Treatment Targets with Oral Semaglutide: A Short-Term Cost-Effectiveness Analysis in the United States
Abstract Introduction Oral semaglutide is the first orally administered glucagon-like peptide-1 receptor agonist for the treatment of type 2 diabetes, and has been evaluated in the PIONEER clinical trial program. These trials assessed the proportions of patients achieving single and composite endpoints, encompassing glycemic control [defined in terms of glycated hemoglobin (HbA1c)], weight loss, and hypoglycemia. The present study...
Latest Results for Advances in T...
00:43
Prevalence of Anal Fistulas in Europe: Systematic Literature Reviews and Population-Based Database Analysis
Abstract Introduction Despite the fact that perianal fistulas are associated with significant morbidity and impaired quality of life, their prevalence in Europe is unknown. The aim of this study was to estimate the prevalence of perianal fistulas in Europe, overall and according to etiology. Methods Two independent literature reviews were performed...
Latest Results for Advances in T...
00:43
Pollen-sensitive individuals have specific psychological profiles
Abstract It was shown that allergic diseases can have a psychosomatic component, and it may be important to consider it in the allergy treatment. So the aim of the study was to determine the presence of a leading psycho-type in a group of subjects with a confirmed diagnosis of seasonal allergy in order to improve both medical care and information delivery to patients. The study was carried out among adult men and women using the MMPI (The Minnesota Multiphasic Personality Inventory)...
Latest Results for Aerobiologia
Mon Nov 11, 2019 14:35
Quality Assessment of Online Information on Body Contouring Surgery in Postbariatric Patient
Abstract Background Nowadays, we have to face the fact that the Web represents one of the most important sources of information for patients. Postbariatric patients in particular are usually very motivated, and they are enthusiastic users of the Web as a source of information on the different types of surgery they could undergo after their weight loss in order to reshape and remodel their body thus regaining physical and functional wellness...
Latest Results for Aesthetic Plastic Surgery
Mon Nov 11, 2019 02:00
Inflammaging phenotype in rhesus macaques is associated with a decline in epithelial barrier-protective functions and increased pro-inflammatory function in CD161-expressing cells
Abstract The development of chronic inflammation, called inflammaging, contributes to the pathogenesis of age-related diseases. Although it is known that both B and T lymphocyte compartments of the adaptive immune system deteriorate with advancing age, the impact of aging on immune functions of Th17-type CD161-expressing innate immune cells and their role in inflammaging remain incompletely understood. Here, utilizing the nonhuman primate model of rhesus macaques, we report that...
Latest Results for AGE
Mon Nov 11, 2019 02:00
Anaerophilus nitritogenes gen. nov., sp. nov., isolated from salt lake sediment in Xinjiang Province, China
Abstract An obligately anaerobic, nitrate-reducing bacterial strain (MJB2T) was isolated from sediments of saline in Xinjiang province of China. Cells were Gram-stain-positive rods and motile by means of flagella and formed endospores. The novel strain MJB2T was able to grow at 15–37 °C (optimum 28–30 °C), pH 5.8–9.4 (optimum 7.8) and with 1.0–7.0% NaCl (optimum 5.0–6.0%, w/v). Sulfate, sulfite, thiosulfate, elemental sulfur, nitrite and Fe(III) were not used as terminal electron...
Latest Results for Antonie van Leeuwenhoek
Mon Nov 11, 2019 02:00
Effects of arsenic exposure on d -serine metabolism in the hippocampus of offspring mice at different developmental stages
Abstract The main purpose of this study was to verify the hypothesis that cognitive dysfunctions induced by arsenic exposure were related to the changes of d-serine metabolism in the hippocampus of offspring mice. Mother mice and their offsprings were exposed to 0, 15, 30 or 60 mg/L sodium arsenite (NaAsO2) through drinking water from the first day of gestation until the end of lactation. d-serine levels in the hippocampus of mice of postnatal day (PND) 10, 20 and 40 were examined...
Latest Results for Archives of Toxicology
Mon Nov 11, 2019 02:00
Development of a neural rosette formation assay (RoFA) to identify neurodevelopmental toxicants and to characterize their transcriptome disturbances
Abstract The first in vitro tests for developmental toxicity made use of rodent cells. Newer teratology tests, e.g. developed during the ESNATS project, use human cells and measure mechanistic endpoints (such as transcriptome changes). However, the toxicological implications of mechanistic parameters are hard to judge, without functional/morphological endpoints. To address this issue, we developed a new version of the human stem cell-based test STOP-tox(UKN). For this purpose,...
Latest Results for Archives of Toxicology
Mon Nov 11, 2019 02:00

Preprocedural ultrasound versus landmark techniques for spinal anesthesia performed by novice residents in elderly: a randomized controlled trial
Abstract Background Spinal anesthesia using the midline approach might be technically difficult in geriatric population. We hypothesized that pre-procedural ultrasound (US)-guided paramedian technique and pre-procedural US-guided midline technique would result in a different spinal anesthesia success rate at first attempt when compared with the conventional landmark-guided midline technique in elderly patients. ...
Latest Results for BMC Anesthesi...
Mon Nov 11, 2019 02:00
Hypoxia preconditioning attenuates lung injury after thoracoscopic lobectomy in patients with lung cancer: a prospective randomized controlled trial
Abstract Background Hypoxic preconditioning (HPC) may protect multiple organs from various injuries. We hypothesized that HPC would reduce lung injury in patients undergoing thoracoscopic lobectomy. Methods In a prospective randomized controlled trial, 70 patients undergoing elective thoracoscopic lobectomy were randomly allocated to the HPC...
Latest Results for BMC Anesthesi...
Mon Nov 11, 2019 02:00
The influence of the infusion of ephedrine and phenylephrine on the hemodynamic stability after subarachnoid anesthesia in senior adults - a controlled randomized trial
Abstract Background We studied the influence of ephedrine or phenylephrine infusion administered immediately after spinal anesthesia (SA) on hemodynamics in elderly orthopedic patients. Methods A prospective, randomized, double-blind, placebo-controlled study. After a subarachnoid injection of 15 mg of levobupivacaine,...
Latest Results for BMC Anesthesi...
Mon Nov 11, 2019 02:00
Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis
Abstract Background Hepatoma-derived growth factor (HDGF) participates in angiogenesis and represents a negative prognostic factor in oral cancer. The current study was designed to elucidate the regulatory mechanism between HDGF and vascular endothelial growth factor (VEGF) and the clinical impact of oral cancer. Methods TCGA data and surgical...
Latest Results for BMC Cancer
Mon Nov 11, 2019 02:00
Red blood cell distribution width and platelet counts are independent prognostic factors and improve the predictive ability of IPI score in diffuse large B-cell lymphoma patients
Abstract Background Elevated red blood cell distribution width (RDW) and decreased platelet count (PLT) can be clinically relevant to the prognosis in cancer patients. However, their prognostic values in patients with diffuse large B-cell lymphoma (DLBCL) need to be further explored. Methods Healthy donors (n = 130) and patients with DLBCL (n = 349)...
Latest Results for BMC Cancer
Mon Nov 11, 2019 02:00
Longitudinal associations between BMI change and the risks of colorectal cancer incidence, cancer-relate and all-cause mortality among 81,388 older adults
Abstract Background It remains controversial whether weight change could influence the risks of colorectal cancer (CRC) and mortality. This study aimed to quantify the associations between full-spectrum changes in body mass index (BMI) and the risks of colorectal cancer (CRC) incidence, cancer-related and all-cause mortality among midlife to elder population. Methods...
Latest Results for BMC Cancer
Mon Nov 11, 2019 02:00
Technical advance in targeted NGS analysis enables identification of lung cancer risk-associated low frequency TP53, PIK3CA, and BRAF mutations in airway epithelial cells
Abstract Background Standardized Nucleic Acid Quantification for SEQuencing (SNAQ-SEQ) is a novel method that utilizes synthetic DNA internal standards spiked into each sample prior to next generation sequencing (NGS) library preparation. This method was applied to analysis of normal appearing airway epithelial cells (AEC) obtained by bronchoscopy in an effort to define a somatic mutation field effect associated with lung cancer...
Latest Results for BMC Cancer
Mon Nov 11, 2019 02:00
Sedative and hypnotic effects of compound Anshen essential oil inhalation for insomnia
Abstract Backgrounds The chemical composition of many essential oils indicates that they have sedative and hypnotic effects, but there is still a lack of systematic studies on the sedative and hypnotic effects of essential oils. In addition, aromatherapy does not seem to have the side effects of many traditional psychotropic substances, which is clearly worthwhile for further clinical and scientific research. The clinical application...
Latest Results for BMC Complementary and Alternative Medicine
Mon Nov 11, 2019 02:00
Studies on antidiarrheal and laxative activities of aqueous-ethanol extract of Asphodelus tenuifolius and underlying mechanisms
Abstract Background Asphodelus tenuifolius Cav. (Asphodelaceae) has traditional reputability in treatment of diarrhea and constipation but no scientific study has been reported for its gastrointestinal effects. Present study was conducted to evaluate antidiarrheal and laxative activities of the plant. Methods Aqueous-ethanol crude extract of...
Latest Results for BMC Complementary and Alternative Medicine
Mon Nov 11, 2019 02:00
Prevalence, and health- and sociodemographic associations for visits to traditional and complementary medical providers in the seventh survey of the Tromsø study
Abstract Background Patient-centered culturally sensitive health care (PC-CSHC) has emerged as a primary approach to health care. This care focuses on the cultural diversity of the patients rather than the views of the health care professionals. PC-CSHC enables the patient to feel comfortable, respected, and trusted in the health care delivery process. As users of traditional and complementary medicine (T&CM) rarely inform their...
Latest Results for BMC Complementary and Alternative Medicine
Mon Nov 11, 2019 02:00
Successful management of severe diabetic ketoacidosis in a patient with type 2 diabetes with insulin allergy: a case report
Abstract Background Diabetic ketoacidosis (DKA) is an acute, major, life-threatening complication of diabetes that requires immediate treatment. Allergic reaction to insulin is rare, especially when using recombinant human insulin. The clinical presentation of insulin allergy can range from minor local symptoms to a severe generalized allergic reaction such as anaphylaxis. A limited number of cases have been reported on the treatment...
Latest Results for BMC Endocrine...
Mon Nov 11, 2019 02:00
Agenesis of the dorsal pancreas presenting with diabetic ketoacidosis – a case report and literature review
Abstract Background Agenesis of the dorsal pancreas (ADP) is clinically rare, and it is usually accompanied by abdominal pain. Various disorders of glucose metabolism associating with ADP have been reported, but there are only two studies reporting a correlation between ADP and DKA in English literature. Case presentation We present a case of...
Latest Results for BMC Endocrine...
Mon Nov 11, 2019 02:00
Value-based genomic screening: exploring genomic screening for chronic diseases using triple value principles
Abstract Background Genomic screening has unique challenges which makes it difficult to easily implement on a wide scale. If the costs, benefits and tradeoffs of investing in genomic screening are not evaluated properly, there is a risk of wasting finite healthcare resources and also causing avoidable harm. Main text If healthcare professionals...
Latest Results for BMC Health Services Research
Mon Nov 11, 2019 02:00
The Discharge Communication Study: research protocol for a mixed methods study to investigate and triangulate discharge communication experiences of patients, GPs, and hospital professionals, alongside a corresponding discharge letter sample
Abstract Background Discharge letters are crucial during care transitions from hospital to home. Research indicates a need for improvement to increase quality of care and decrease adverse outcomes. These letters are often sent from the hospital discharging physician to the referring clinician, typically the patient’s General Practitioner (GP) in the UK, and patients may or may not be copied into them. Relatively little is known about...
Latest Results for BMC Health Services Research
Mon Nov 11, 2019 02:00
Cost-effectiveness of the SLIMMER diabetes prevention intervention in Dutch primary health care: economic evaluation from a randomised controlled trial
Abstract Background Although evidence is accumulating that lifestyle modification may be cost-effective in patients with prediabetes, information is limited on the cost-effectiveness of interventions implemented in public health and primary health care settings. Evidence from well-conducted pragmatic trials is needed to gain insight into the realistic cost-effectiveness of diabetes prevention interventions in real-world settings....
Latest Results for BMC Health Services Research
Mon Nov 11, 2019 02:00
Age estimation in three distinct east Asian population groups using southern Han Chinese dental reference dataset
Abstract Background Dental age estimation can assist in the identification of victims following natural disasters and it can also help to solve birth date disputes in individuals involved in criminal activities. A reference dataset (RDS) has been developed from the dental development of 2306 subjects of southern Han Chinese origin and subsequently validated. This study aimed to test the applicability of the southern Han Chinese dental...
Latest Results for BMC Oral Health
Mon Nov 11, 2019 02:00
Follicular lymphoid hyperplasia of the posterior maxillary site presenting as uncommon entity: a case report and review of the literature
Abstract Background Follicular lymphoid hyperplasia (FLH) is characterized by an increased number and size of lymphoid follicles. In some cases, the etiology of FLH is unclear. FLH in the oral and maxillofacial region is an uncommon benign entity which may resemble malignant lymphoma clinically and histologically. Case presentation We report...
Latest Results for BMC Oral Health
Mon Nov 11, 2019 02:00
Factors influencing incidents of complications while using nickel-titanium rotary instruments for root canal treatment
Abstract Background To investigate the complications associated with the use of nickel titanium rotary instruments (NiTi-RIs) for root canal treatments (RCTs), in Saudi Arabia dental practice, and to explore the influencing factors. Methods After obtaining an ethical approval, two pilot studies were conducted to formulate the final questionnaire....
Latest Results for BMC Oral Health
Mon Nov 11, 2019 02:00
Magnitude of intestinal parasitic infections and associated factors among food handlers working at Woldia University student’s cafeteria, Northeastern Ethiopia: an institution based cross-sectional study
Abstract Objectives The main aim of this study was to assess the Magnitude of intestinal parasitic infections and associated factors among food handlers working at Woldia University Student’s cafeteria, Northeastern Ethiopia. Institutional based cross-sectional study was conducted among 256 study participants in Woldia university student’s cafeteria, Northern Ethiopia. Systematic random sampling method was used to select the study...
Latest Results for BMC Research Notes
Fri Nov 08, 2019 02:00

Structural connectivity and functional properties of the macaque superior parietal lobule
Abstract Despite the consolidated belief that the macaque superior parietal lobule (SPL) is entirely occupied by Brodmann’s area 5, recent data show that macaque SPL also hosts a large cortical region with structural and functional features similar to that of Brodmann’s area 7. According to these data, the anterior part of SPL is occupied by a somatosensory-dominated cortical region that hosts three architectural and functional distinct regions (PE, PEci, PEip) and the caudal half...
Latest Results for Brain Structure and Function
Mon Nov 11, 2019 02:00

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου