The "International Study of Wheezing in Infants (EISL)", is a cross-sectional, population-based study, based on ISAAC. "(Http // www.isaac.auckland.ac.nz). It uses a validated questionnaire on early wheezing and risk/protective factors.
Thu Nov 14, 2019 02:00
GSP301 is an investigational fixed-dose combination nasal spray of olopatadine hydrochloride (antihistamine) and mometasone furoate (corticosteroid).
Thu Nov 14, 2019 02:00
DiGeorge syndrome (DGS) is the most common congenital chromosome deletion syndrome which appears in 1:4000 live births as the result of 22q11.2 microdeletion1. It is a primary immunodeficiency disease (PID), characterized with decreased T-cell numbers1,2. There is a growing body of evidence that DGS is associated with humoral immune deficiency (ID) as the result of B-lymphocyte functional deficit, leading to hypogammaglobulinemia1,2. Patients with DGS show increased incidence of infection and autoimmune...
Thu Nov 14, 2019 02:00
GINA, Global Initiative for Asthma, was launched in 1993 in collaboration with the National Heart, Lung, and Blood Institute, National Institutes of Health, and the World Health Organization. to improve the prevention and management of asthma worldwide. Their science committee updates asthma guidelines yearly and the 20191 report’s goals were to reduce the risk of serious asthma-related exacerbations: to avoid patient reliance on quick-relief medication: and to update asthma treatment goals. In the...
Thu Nov 14, 2019 02:00
This is an exciting time in the field of allergy and immunology. The advent of biologic medications has undoubtedly revolutionized the landscape of asthma management. Many patients previously condemned to frequent hospitalizations, emergency department visits, and prednisone bursts can now live with minimal symptomatology. However, the fact that these biologics remain in their infancy poses several questions beyond eligibility criteria, choice of biologic, and dosing. Questions regarding duration...
Thu Nov 14, 2019 02:00
The School Access to Emergency Epinephrine Act was signed into law by President Obama on November 13, 2013 with bipartisan support (Public Law 113-48). The law amended the Public Health Service Act to increase the preference given to certain asthma-related grants in states that allow trained school personnel to administer epinephrine and maintain a stock epinephrine supply to treat suspected anaphylaxis. To qualify, states are also required to provide civil liability protection to trained staff acting...
Thu Nov 14, 2019 02:00
Studies suggest that obstructive sleep apnea (OSA) is associated with suboptimal disease control and worse chronic severity of asthma. However, little is known about the relations of OSA with acute asthma severity in hospitalized patients.
Thu Nov 14, 2019 02:00
Asparaginase is a chemotherapeutic used to treat hematological malignancies. Hypersensitivity reactions to native asparaginase (L-asparaginase) are described in up to 60% of patients1, in which case switching to alternative forms of asparaginase is recommended: pegylated-asparaginase (PEG-asparaginase), a readily available formulation, or Erwinia-asparaginase2; which is currently scarce. Although PEG-asparaginase is considered hypoallergenic, up to 25% of patients receiving it have allergic reactions3.
Thu Nov 14, 2019 02:00
Thu Nov 14, 2019 11:47
Publication date: Available online 14 November 2019Source: Autoimmunity ReviewsAuthor(s): Iago Pinal-Fernandez, Katherine Pak, Maria Casal-Dominguez, Yuji Hosono, Christopher Mecoli, Lisa Christopher-Stine, Andrew L. Mammen
Thu Nov 14, 2019 12:39
Publication date: Available online 14 November 2019Source: Autoimmunity ReviewsAuthor(s): Ennio Giulio Favalli, Marco Matucci-Cerinic, Zoltan SzekaneczAbstractRheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that, if untreated, can lead to disability and reduce the life expectancy of affected patients. Over the last two decades the improvement of knowledge of the pathogenetic mechanisms leading to the development of the disease has profoundly changed the treatment strategies...
Thu Nov 14, 2019 12:39
Comparative United States autoimmune disease rates for 2010–2016 by sex, geographic region, and race
Publication date: Available online 14 November 2019Source: Autoimmunity ReviewsAuthor(s): Melissa H. Roberts, Esther ErdeiAbstractPurpose: AIDs may disproportionately impact specific racial groups, but autoimmune (AID) prevalence information by minority racial group is sparse for many AIDs. The objective of this analysis was to supplement previously published AID prevalence rates by providing information on race rate ratios (minority race populations compared to Caucasian populations) in the United...
Thu Nov 14, 2019 12:39
Publication date: Available online 13 November 2019Source: Autoimmunity ReviewsAuthor(s): Guojun Geng, Xiuyi Yu, Jie Jiang, Xinhua YuAbstractParaneoplastic autoimmune disorders (PAD) represent a group of autoimmune diseases associated with neoplasms. As a consequence of a remote autoimmunity-mediated effect, PAD are found in multiple organs or tissues, including the skin, blood and nervous system. Compared with non-paraneoplastic autoimmune diseases, PAD have different aetiologies, pathologies, disease...
Thu Nov 14, 2019 12:39
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