Publication date: Available online 2 November 2019Source: BrachytherapyAuthor(s): Nelson N. Stone, Vassilios Skouteris, Panagiotis-Marios MetsinisAbstractPURPOSETo determine if transperineal mapping biopsy (TPMB) can improve the selection of brachytherapy alone (BT) or brachytherapy boost (BTB) in men with localized prostate cancer.Methods and MaterialsTwo hundred and eighteen men underwent TPMB with a mean of 48.6 cores retrieved. Comparisons were made between prebiopsy risk features and biopsy...
Sun Nov 03, 2019 15:48
Publication date: Available online 2 November 2019Source: BrachytherapyAuthor(s): Miguel A. Berenguer Frances, Isabel Linares-Galiana, Rut Cañas Cortés, Susanna Marín i Borrás, Cristina Gutiérrez Miguélez, Dina Najjari, Andrea Slocker, Cinta Bellobí, María Santacana, María Pané Foix, M. Henar Alonso, Arturo Navarro-Martin, Silvia Comas Antón, Ferran GuedeaAbstractPurposeWe hypothesized that radiation doses delivered with high-dose-rate (HDR) and pulsed-dose-rate (PDR) brachytherapy in patients with...
Sun Nov 03, 2019 15:48
Abstract Purpose To study if second-generation antipsychotic (S-GA) use during pregnancy is associated with an increased risk of pregnancy and neonatal complications. Methods A population-based birth cohort study using national register data extracted from the “Drugs and Pregnancy” database in Finland, years 1996–2016. The sampling frame included 1,181,090...
Sun Nov 03, 2019 02:00
Publication date: Available online 2 November 2019Source: British Journal of Oral and Maxillofacial SurgeryAuthor(s): M. Kimura, K. Ishibashi, A. Shibata, S. Nishiwaki, M. Umemura
Sun Nov 03, 2019 15:00
Publication date: Available online 2 November 2019Source: Dental MaterialsAuthor(s): Nicoleta Ilie, N. Dorin RuseAbstractObjectiveTo compare shear bond strength (SBS) and interfacial fracture toughness (IKIC) results when assessing the effect of surface roughness and thermocycling on the adherence of a resin composite luting agent (RCLA) to a CAD/CAM resin composite block (RCB).MethodsTetric CAD HT along with the recommended bonding system, Adhese Universal and Variolink Esthetic LC, were used. Surface...
Sun Nov 03, 2019 14:57
Publication date: Available online 2 November 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Jitka Veldema, Petra JansenAbstractObjectiveErgometer training is routinely used in stroke rehabilitation. How robust is the evidence of its effects?Data sourceThe PubMed database and PEDro database were reviewed prior to 22/01/2019.Study selectionRandomized controlled trials investigating the effects of ergometer training on stroke recovery were selected.Data extractionTwo reviewers...
Sun Nov 03, 2019 14:55
Publication date: Available online 2 November 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Nai-Fang Chi, Yi-Chieh Huang, Hsiao-Yean Chiu, Hsiu-Ju Chang, Hui-Chuan HuangAbstractObjectiveTo evaluate the effects of home-based rehabilitation on improving physical function in home-dwelling patients after a stroke.Data sourcesVarious electronic databases, including PubMed, CINAL, Embase, the Cochrane Central Register of Controlled Trials, and two Chinese datasets (i.e., Chinese...
Sun Nov 03, 2019 14:55
Publication date: Available online 2 November 2019Source: Archives of Physical Medicine and RehabilitationAuthor(s): Alessandro Chiarotto, Leo D. Roorda, Martine H. Crins, Maarten Boers, Raymond W. Ostelo, Caroline B. TerweeAbstractObjectiveTo compare dimensionality, item-level characteristics, scale-level reliability and construct validity of PROMIS® Physical Function short forms (PROMIS-PF) and 24-item Roland Morris Disability Questionnaire (RMDQ-24) in patients with chronic low back pain (LBP).DesignCross-sectional...
Sun Nov 03, 2019 14:55
Genes, Vol. 10, Pages 885: Genome-Wide Analysis of Known and Potential Tetraspanins in Entamoeba histolytica Genes doi: 10.3390/genes10110885 Authors: Tomii Santos Nozaki Tetraspanins are membrane proteins involved in intra- and/or intercellular signaling, and membrane protein complex formation. In some organisms, their role is associated with virulence and pathogenesis. Here, we investigate known and potential tetraspanins in the human intestinal protozoan parasite Entamoeba...
Sun Nov 03, 2019 02:00
Antibodies, Vol. 8, Pages 52: Immunoglobulin for Treating Bacterial Infections: One More Mechanism of Action Antibodies doi: 10.3390/antib8040052 Authors: Sawa Kinoshita Inoue Ohara Moriyama The mechanisms underlying the effects of immunoglobulins on bacterial infections are thought to involve bacterial cell lysis via complement activation, phagocytosis via bacterial opsonization, toxin neutralization, and antibody-dependent cell-mediated cytotoxicity. Nevertheless,...
Sun Nov 03, 2019 02:00
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Marcelo Gomes de Gomes, Muriel Pando Pereira, Flavia Elizabete Guerra Teixeira, Felipe Carvalho, Anne Suely Pinto Savall, Diogo Ferreira Bicca, Eduarda Monteiro Fidelis, Paulo Emilio Botura, Francielli Weber Cibin, Simone Pinton, Sandra Elisa HaasAbstractThe unloaded polymeric nanocapsules (NCs) present incredible characteristics as drug carriers. However, the toxicity caused by NCs with different coatings...
Sun Nov 03, 2019 14:37
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Shangnan Dai, Yunpeng Peng, Yi Zhu, Dalai Xu, Feng Zhu, Wenbin Xu, Qiuyang Chen, Xiaole Zhu, Tongtai Liu, Chaoqun Hou, Junli Wu, Yi MiaoAbstractPrevious studies have reported that increased glycolytic activity enhances chemotherapy resistance in some types of malignancies. However, whether glycolysis influences the curative effect of gemcitabine (GEM) on pancreatic cancer (PC) cells remains unclear. The...
Sun Nov 03, 2019 14:37
Publication date: January 2020Source: Biomedicine & Pharmacotherapy, Volume 121Author(s): Xunjie Zhou, Bo Lu, Deyu Fu, Mingtai Gui, Lei Yao, Jianhua LiAbstractObjectiveEndoplasmic reticulum (ER) stress is involved in hypertension related cardiac remodeling. We aimed to evaluate the effects of Huoxue Qianyang (HXQY) decoction on cardiac remodeling in obese spontaneously hypertensive rats (SHRs), and explore its impacts on the activating transcription factor 6 (ATF6)-C/EBP homologous protein (CHOP)...
Sun Nov 03, 2019 14:37
Publication date: Available online 2 November 2019Source: Sleep MedicineAuthor(s): Svetlana Maskevich, Amy Cassanet, Nicholas B. Allen, John Trinder, Bei BeiAbstractStudy ObjectivesThis study explored the relationship between stress and actigraphy-measured and self-reported sleep in adolescents during periods of restricted (school) and unrestricted (vacation) sleep opportunities. We further examined whether (1) cognitive pre-sleep arousal (PSA) mediated the relationship between stress and sleep onset...
Sun Nov 03, 2019 14:35
Publication date: Available online 2 November 2019Source: Journal of Clinical EpidemiologyAuthor(s): Paul Madley-Dowd, Dheeraj Rai, Stanley Zammit, Jon HeronAbstractObjectiveThe negative control design can be used to provide evidence for whether a prenatal exposure-outcome association occurs by in-utero mechanisms. Assortative mating has been suggested to influence results from negative control designs, though how and why has not yet been adequately explained. We aimed to explain why mutual adjustment...
Sun Nov 03, 2019 14:33
Publication date: Available online 3 November 2019Source: Journal of EthnopharmacologyAuthor(s): Xiaoming Sun, Yi Lv, Lu Huang, Hao Gao, Chaoran Ren, Jingjing Li, Man Bie, Wei Li, Kazuo Koike, Kwok Fai So, Jia XiaoAbstractEthnopharmacological relevanceGogi berry is a traditional food supplement and medical herbal which has been widely used in Eastern Asian countries. Lycium barbarum polysaccharides (LBP) are the major active components of Gogi berry and have been proved to possess a lot of biological...
Sun Nov 03, 2019 14:28
Publication date: Available online 2 November 2019Source: Journal of EthnopharmacologyAuthor(s): Da-Wu Zhang, Shao-Li Wang, Pei-Li Wang, Jian-Peng Du, Zhu-Ye Gao, Cheng-Long Wang, Hao Xu, Da-Zhuo ShiAbstractEthnopharmacological relevanceFufang Chuanxiong capsule consists of Angelica sinensis radix and Chuanxiong rhizome, which are used in the traditional Chinese medicine for the treatment of coronary artery disease, and Xinyue capsule is composed of panax quinquefolius saponin extracted from leaves...
Sun Nov 03, 2019 14:28
Publication date: Available online 2 November 2019Source: Journal of EthnopharmacologyAuthor(s): Fatma Tuğçe Gürağaç Dereli, Mert Ilhan, Esra Küpeli AkkolAbstractEthnopharmacological relevanceIn Turkish folk medicine, infusions and decoctions prepared from the flowers, fruits and aerial parts of Centaurea kurdica Reichardt (Asteraceae) are used as sedative and antidepressant-like effects of various sedative plants have been identified in many studies. The present study was designed to evaluate the...
Sun Nov 03, 2019 14:28
The impact of hypoxaemia on vascular function in lowlanders and high altitude indigenous populations
Abstract Exposure to hypoxia elicits widespread physiological responses that are critical for successful acclimatization; however, these responses may induce apparent maladaptive consequences. For example, recent studies conducted in both the laboratory and field (e.g. high‐altitude) have demonstrated that endothelial function is reduced in hypoxia. Herein, we review the several proposed mechanism(s) pertaining to the observed reduction in endothelial function in hypoxia including: a) changes in...
Sat Nov 02, 2019 16:18
Biomedicines, Vol. 7, Pages 87: Circulating Exosomal miRNA Profiles Predict the Occurrence and Recurrence of Hepatocellular Carcinoma in Patients with Direct-Acting Antiviral-Induced Sustained Viral Response Biomedicines doi: 10.3390/biomedicines7040087 Authors: Itami-Matsumoto Hayakawa Uchida-Kobayashi Enomoto Tamori Mizuno Toyoda Tamura Akutsu Ochiya Kawada Murakami Direct-acting antiviral (DAA) therapy for chronic hepatitis C virus (HCV)...
Sun Nov 03, 2019 02:00
Repair of large defects caused by lip cancer resection is often a challenge for surgeons. The aim of this study is to explore the treatment and outcomes of lower lip reconstruction with a novel surgical procedure after lip cancer ablation. (Source: Journal of Oral and Maxillofacial Surgery)
Sat Nov 02, 2019 00:00
Maxillofacial trauma confers an increased risk of long-term clinical sequelae with a significant economical burden on the healthcare system. Substance use has long been correlated with an increased risk of trauma; yet to date, a comprehensive profile of substance users incurring facial fractures has not been established. We aim to establish patterns and trends of substance use and specific substances in the setting of maxillofacial trauma. (Source: Journal of Oral and Maxillofacial Surgery)
Sat Nov 02, 2019 00:00
Falls are a common cause of the maxillofacial fractures, and falls associated with the loss of consciousness may have a special characteristic. The purpose of this study was to measure the association between types of falls and maxillofacial injury severity. (Source: Journal of Oral and Maxillofacial Surgery)
Sat Nov 02, 2019 00:00
The use of intraoperative imaging may help overcome closed reduction`s insufficiency due to absence of visible feedback for reduction control in isolated zygomatic arch fracture. The aim of this study was to estimate the effect of intraoperative use of 3D imaging by cone-beam computed tomography (CBCT) on reduction accuracy as measured by remaining cortical step and dislocation angle and ultimately its effect on the need for second surgery. (Source: Journal of Oral and Maxillofacial Surgery)
Sat Nov 02, 2019 00:00
To compare the accuracy of landmark-based with a voxel-based 3D analysis to quantify osseous movements of the maxilla and mandible following bimaxillary osteotomies. (Source: Journal of Oral and Maxillofacial Surgery)
Sat Nov 02, 2019 00:00
Embedded third molar surgery is the most frequent oral-maxillofacial surgical procedure performed. The purpose of this study was to assess the clinical effect of submucosal dexmedetomidine (dex) on decreasing postoperative edema, trismus, and pain after surgical molar extraction. (Source: Journal of Oral and Maxillofacial Surgery)
Thu Oct 10, 2019 00:00
Biomolecules, Vol. 9, Pages 691: Ginkgo Biloba Extract Alleviates Methotrexate-Induced Renal Injury: New Impact on PI3K/Akt/mTOR Signaling and MALAT1 Expression Biomolecules doi: 10.3390/biom9110691 Authors: Sherif Al-Shaalan Sabry Renal injury induced by the chemotherapeutic agent methotrexate (MTX) is a serious adverse effect that has limited its use in the treatment of various clinical conditions. The antioxidant activity of Ginkgo biloba extract (GB) was reported to mitigate...
Sun Nov 03, 2019 02:00
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