Antibiotics, Vol. 8, Pages 230: Harnessing the Potential of Killers and Altruists within the Microbial Community: A Possible Alternative to Antibiotic Therapy? Antibiotics doi: 10.3390/antibiotics8040230 Authors: Ikryannikova Kurbatov Soond Zamyatnin In the context of a post-antibiotic era, the phenomenon of microbial allolysis, which is defined as the partial killing of bacterial population induced by other cells of the same species, may take on greater significance. This...
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Antioxidants, Vol. 8, Pages 575: Dietary Stevioside Supplementation Alleviates Lipopolysaccharide-Induced Intestinal Mucosal Damage through Anti-Inflammatory and Antioxidant Effects in Broiler Chickens Antioxidants doi: 10.3390/antiox8120575 Authors: Jingle Jiang Lina Qi Zengpeng Lv Song Jin Xihui Wei Fangxiong Shi The study was conducted to investigate the effects of dietary stevioside (STE) supplementation on the lipopolysaccharide (LPS)-induced intestinal mucosal damage...
Antioxidants, Vol. 8, Pages 576: Astaxanthin Inhibits Mitochondrial Permeability Transition Pore Opening in Rat Heart Mitochondria Antioxidants doi: 10.3390/antiox8120576 Authors: Baburina Krestinin Odinokova Sotnikova Kruglov Krestinina The mitochondrion is the main organelle of oxidative stress in cells. Increased permeability of the inner mitochondrial membrane is a key phenomenon in cell death. Changes in membrane permeability result from the opening of the mitochondrial...
Antioxidants, Vol. 8, Pages 574: Batryticatus Bombyx Protects Dopaminergic Neurons Against MPTP-Induced Neurotoxicity by Inhibiting Oxidative Damage Antioxidants doi: 10.3390/antiox8120574 Authors: Lim Kim Moon Ryu Lee Park Oxidative stress plays an important role in the degeneration of dopaminergic neurons in Parkinson’s disease (PD). Altered redox homeostasis in neurons interferes with several biological processes, ultimately leading to neuronal death....
Antioxidants, Vol. 8, Pages 577: Sulforaphane Protects Cells against Lipopolysaccharide-Stimulated Inflammation in Murine Macrophages Antioxidants doi: 10.3390/antiox8120577 Authors: Ruhee Ma Suzuki Inflammation is an essential part for the general or innate immune defenses to defend against tissue damage and accelerate the curing process by providing protection against pathogens. Sulforaphane (SFN) is a natural isothiocyanate that has potential properties against inflammation,...
Antioxidants, Vol. 8, Pages 572: Effects of Food Processing on In Vivo Antioxidant and Hepatoprotective Properties of Green Tea Extracts Antioxidants doi: 10.3390/antiox8120572 Authors: Xiao-Yu Xu Jie Zheng Jin-Ming Meng Ren-You Gan Qian-Qian Mao Ao Shang Bang-Yan Li Xin-Lin Wei Hua-Bin Li Food processing can affect the nutrition and safety of foods. A previous study showed that tannase and ultrasound treatment could significantly increase the antioxidant activities...
Antioxidants, Vol. 8, Pages 573: Functional Components, Antioxidant Activity and Hypoglycemic Ability Following Simulated Gastro-Intestinal Digestion of Pigments from Walnut Brown Shell and Green Husk Antioxidants doi: 10.3390/antiox8120573 Authors: Yanan Sun Shanshan Li Fanhang Zeng Jingyi Qi Wen Qin Cui Tan Qingying Luo Dingtao Wu Qing Zhang Derong Lin Hong Chen To assess the effects of digestion on the functional components of walnut pigment and their...
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Atmosphere, Vol. 10, Pages 732: The Influence of Tornado Activity, Impact, Memory, and Sentiment on Tornado Perception Accuracy among College Students Atmosphere doi: 10.3390/atmos10120732 Authors: Jason C. Senkbeil Kelsey N. Ellis Jacob R. Reed A survey consisting of open-ended and closed responses was administered at three universities in the eastern USA. The home counties of survey participants represented climatological tornado risks spanning from rarely impacted to frequently...
Atmosphere, Vol. 10, Pages 731: A Study on Microscale Wind Simulations with a Coupled WRF–CFD Model in the Chongli Mountain Region of Hebei Province, China Atmosphere doi: 10.3390/atmos10120731 Authors: Li Sun Zhang Zhao Zhang To ensure successful hosting of the 2022 Olympic Winter Games, a comprehensive understanding of the wind field characteristics in the Chongli Mountain region is essential. The purpose of this research was to accurately simulate the microscale wind...
Atmosphere, Vol. 10, Pages 730: Urban Areas and Urban–Rural Contrasts under Climate Change: What Does the EURO-CORDEX Ensemble Tell Us?—Investigating Near Surface Humidity in Berlin and Its Surroundings Atmosphere doi: 10.3390/atmos10120730 Authors: Langendijk Rechid Jacob Climate change will impact urban areas. Decision makers need useful climate information to adapt adequately. This research aims to improve understanding of changes in moisture and temperature projected under...
Atmosphere, Vol. 10, Pages 729: In-Field Emission Measurements from Biogas and Liquified Petroleum Gas (LPG) Stoves Atmosphere doi: 10.3390/atmos10120729 Authors: Weyant Thompson Lam Upadhyay Shrestha Maharjan Rai Adhikari Fox Pokhrel Household air pollution from solid fuel cooking causes millions of deaths each year and contributes to climate change. These emissions can be reduced if households transition to cleaner cooking fuels such as LPG or...
Atmosphere, Vol. 10, Pages 728: Parameterization of The Single-Scattering Properties of Dust Aerosols in Radiative Flux Calculations Atmosphere doi: 10.3390/atmos10120728 Authors: Wang Su Li Wang Ge In this study, we present parameterization schemes of dust single-scattering properties (SSPs) in order to establish a fast and accurate way to obtain the SSPs for dust shortwave radiative flux calculation. Based on the assumption that dust particles are spheroids, we represent...
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Behavioral Sciences, Vol. 9, Pages 121: The Relationships between Physical Activity, Self-Efficacy, and Quality of Life in People with Multiple Sclerosis Behavioral Sciences doi: 10.3390/bs9120121 Authors: Guicciardi Carta Pau Cocco Regular physical activity (PA) can enhance the physical and mental health of people with Multiple Sclerosis (MS) because of its impact on muscular strength, mobility, balance, walking, fatigue, pain and health-related quality of life (HRQoL)....
Behavioral Sciences, Vol. 9, Pages 120: Individual Variation and the Bilingual Advantage—Factors that Modulate the Effect of Bilingualism on Cognitive Control and Cognitive Reserve Behavioral Sciences doi: 10.3390/bs9120120 Authors: van den Noort Struys Bosch This editorial is an introduction to the special issue ‘Individual variation and the bilingual advantage—factors that modulate the effect of bilingualism on cognitive control’[...]
Behavioral Sciences, Vol. 9, Pages 119: The Study of Network Community Capacity to be a Subject: Digital Discursive Footprints Behavioral Sciences doi: 10.3390/bs9120119 Authors: Anatoly N. Voronin Taisiya A. Grebenschikova Tina A. Kubrak Timofey A. Nestik Natalya D. Pavlova The article is devoted to the assessment of the network community as a collective subject, as a group of interconnected and interdependent persons performing joint activities. According to the main research...
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Biomolecules, Vol. 9, Pages 764: Preparation and Evaluation of the ZnO NP–Ampicillin/Sulbactam Nanoantibiotic: Optimization of Formulation Variables Using RSM Coupled GA Method and Antibacterial Activities Biomolecules doi: 10.3390/biom9120764 Authors: Sharma Singh Pandey Mishra Kulsoom Dasgupta Khan El-Enshasy Haque Nanoparticles (NPs) possessing antibacterial activity represent an effective way of overcoming bacterial resistance. In the present work,...
Biomolecules, Vol. 9, Pages 763: Evolutionary Conservation and Expression Patterns of Neutral/Alkaline Invertases in Solanum Biomolecules doi: 10.3390/biom9120763 Authors: Pan Guo Chai Cheng Ruan Ye Wang Yao Zhou Li Deng Jin Liu Wan The invertase gene family in plants is composed of two subfamilies of enzymes, namely, acid- and neutral/alkaline invertases (cytosolic invertase, CIN). Both can irreversibly cleave sucrose into fructose...
Biomolecules, Vol. 9, Pages 765: The Plasma Factor XIII Heterotetrameric Complex Structure: Unexpected Unequal Pairing within a Symmetric Complex Biomolecules doi: 10.3390/biom9120765 Authors: Singh Nazabal Kaniyappan Pellequer Wolberg Imhof Oldenburg Biswas Factor XIII (FXIII) is a predominant determinant of clot stability, strength, and composition. Plasma FXIII circulates as a pro-transglutaminase with two catalytic A subunits and two carrier-protective...
Biomolecules, Vol. 9, Pages 762: Clerodane Diterpene Ameliorates Inflammatory Bowel Disease and Potentiates Cell Apoptosis of Colorectal Cancer Biomolecules doi: 10.3390/biom9120762 Authors: Zheng Lin Tseng Tsai Lue Chia Woon Fu Weng Inflammatory bowel disease (IBD) is general term for ulcerative colitis and Crohn’s disease, which is chronic intestinal and colorectal inflammation caused by microbial infiltration or immunocyte attack. IBD is...
Biomolecules, Vol. 9, Pages 761: Nucleotide Transport and Metabolism in Diatoms Biomolecules doi: 10.3390/biom9120761 Authors: Gruber Haferkamp Plastids, organelles that evolved from cyanobacteria via endosymbiosis in eukaryotes, provide carbohydrates for the formation of biomass and for mitochondrial energy production to the cell. They generate their own energy in the form of the nucleotide adenosine triphosphate (ATP). However, plastids of non-photosynthetic tissues, or during...
Biomolecules, Vol. 9, Pages 760: Lipoprotein(a) as Orchestrator of Calcific Aortic Valve Stenosis Biomolecules doi: 10.3390/biom9120760 Authors: Schnitzler Ali Groenen Kaiser Kroon Aortic valve stenosis (AVS) is the most prevalent disease in the Western World with exponentially increased incidence with age. If left untreated, the yearly mortality rates increase up to 25%. Currently, no effective pharmacological interventions have been established to treat or prevent...
Biomolecules, Vol. 9, Pages 757: Gene Expression Profiling of MicroRNAs in HPV-Induced Warts and Normal Skin Biomolecules doi: 10.3390/biom9120757 Authors: AL-Eitan Alghamdi Tarkhan Al-Qarqaz : Infection with the human papillomavirus (HPV) is a common occurrence among the global population, with millions of new cases emerging on an annual basis. Dysregulated microRNA (miRNA) expression is increasingly being identified to play a role in a number of different diseases, especially...
Biomolecules, Vol. 9, Pages 758: Bioactive Compounds: Natural Defense Against Cancer? Biomolecules doi: 10.3390/biom9120758 Authors: Shonia Subramaniam Kanga Rani Selvaduray Ammu Kutty Radhakrishnan Cancer is a devastating disease that has claimed many lives. Natural bioactive agents from plants are gaining wide attention for their anticancer activities. Several studies have found that natural plant-based bioactive compounds can enhance the efficacy of chemotherapy, and in some...
Biomolecules, Vol. 9, Pages 756: Soluble Fraction from Lysates of Selected Probiotic Strains Differently Influences Re-Epithelialization of HaCaT Scratched Monolayer through a Mechanism Involving Nitric Oxide Synthase 2 Biomolecules doi: 10.3390/biom9120756 Authors: Lombardi Palumbo Mattei Augello Cifone Giuliani Cinque A growing body of evidence supports the use of probiotics in the treatment of several skin conditions, including wounds. Even if in vitro and...
Biomolecules, Vol. 9, Pages 759: Zhankuic Acids A, B and C from Taiwanofungus Camphoratus Act as Cytotoxicity Enhancers by Regulating P-Glycoprotein in Multi-Drug Resistant Cancer Cells Biomolecules doi: 10.3390/biom9120759 Authors: Teng Wang Wu Hung Hung : Since P-glycoprotein (P-gp)-related multidrug resistance (MDR) remains the most important unsolved problem in cancer treatment, scientists are attempting to find potential structures from natural resources. The aim...
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Brain Sciences, Vol. 9, Pages 334: Cognitive Mediators of School-Related Socio-Adaptive Behaviors in ASD and Intellectual Disability Pre- and Adolescents: A Pilot-Study in French Special Education Classrooms Brain Sciences doi: 10.3390/brainsci9120334 Authors: Mazon Fage Consel Amestoy Hesling Bouvard Etchegoyhen Sauzéon The school inclusion of students with autism is still a challenge. To address the cognitive underpinnings of school-related adaptive behaviors,...
Brain Sciences, Vol. 9, Pages 333: Muscle-Specific Modulation of Spinal Reflexes in Lower-Limb Muscles during Action Observation with and without Motor Imagery of Walking Brain Sciences doi: 10.3390/brainsci9120333 Authors: Kaneko Masugi Usuda Yokoyama Nakazawa Action observation (AO) and motor imagery (MI) are useful techniques in neurorehabilitation. Previous studies have reported that AO and MI facilitate corticospinal excitability only in those muscles that are active...
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Cancers, Vol. 11, Pages 1844: Mutations in Splicing Factor Genes in Myeloid Malignancies: Significance and Impact on Clinical Features Cancers doi: 10.3390/cancers11121844 Authors: Valeria Visconte Megan O. Nakashima Heesun J. Rogers Components of the pre-messenger RNA splicing machinery are frequently mutated in myeloid malignancies. Mutations in LUC7L2, PRPF8, SF3B1, SRSF2, U2AF1, and ZRSR2 genes occur at various frequencies ranging between 40% and 85% in different subtypes of...
Cancers, Vol. 11, Pages 1843: Tumour-Secreted Protein S (ProS1) Activates a Tyro3-Erk Signalling Axis and Protects Cancer Cells from Apoptosis Cancers doi: 10.3390/cancers11121843 Authors: Nour Al Kafri Sassan Hafizi The TAM subfamily (Tyro3, Axl, MerTK) of receptor tyrosine kinases are implicated in several cancers, where they have been shown to support primary tumorigenesis as well as secondary resistance to cancer therapies. Relatively little is known about the oncogenic role of...
Cancers, Vol. 11, Pages 1842: A Review of the Potential Role of Human Cytomegalovirus (HCMV) Infections in Breast Cancer Carcinogenesis and Abnormal Immunity Cancers doi: 10.3390/cancers11121842 Authors: Jürgen Geisler Joel Touma Afsar Rahbar Cecilia Söderberg-Nauclér Katja Vetvik Previously recognized classical human onco-viruses can regulate complex neoplastic events, and are estimated to play a role during carcinogenesis in 15–20% of cancer cases. Although the...
Cancers, Vol. 11, Pages 1845: Myoinvasive Pattern as a Prognostic Marker in Low-Grade, Early-Stage Endometrioid Endometrial Carcinoma Cancers doi: 10.3390/cancers11121845 Authors: Ignacio Ruz-Caracuel Jorge L Ramón-Patino Álvaro López-Janeiro Laura Yébenes Alberto Berjón Alicia Hernández Alejandro Gallego Victoria Heredia-Soto Marta Mendiola Andrés Redondo Alberto Peláez-García David Hardisson Low-grade and early Federation for Gynecology and Obstetrics...
Cancers, Vol. 11, Pages 1840: ANLN and TLE2 in Muscle Invasive Bladder Cancer: A Functional and Clinical Evaluation Based on In Silico and In Vitro Data Cancers doi: 10.3390/cancers11121840 Authors: Wu Nitschke Heinkele Weis Worst Eckstein Porubsky Erben : Anilin actin binding protein (ANLN) and transducing-like enhancer protein 2 (TLE2) are associated with cancer patient survival and progression. The impact of their gene expression on progression-free survival...
Cancers, Vol. 11, Pages 1841: Reversal of Epithelial–Mesenchymal Transition by Natural Anti-Inflammatory and Pro-Resolving Lipids Cancers doi: 10.3390/cancers11121841 Authors: Lee Epithelial mesenchymal transition (EMT) is a key process in the progression of malignant cancer. Therefore, blocking the EMT can be a critical fast track for the development of anticancer drugs. In this paper, we update recent research output of EMT and we explore suppression of EMT by natural anti-inflammatory...
Cancers, Vol. 11, Pages 1838: Risk of Optic Pathway Glioma in Neurofibromatosis Type 1: No Evidence of Genotype–Phenotype Correlations in A Large Independent Cohort Cancers doi: 10.3390/cancers11121838 Authors: Melloni Eoli Cesaretti Bianchessi Ibba Esposito Scuvera Morcaldi Micheli Piozzi Avignone Chiapparini Pantaleoni Natacci Finocchiaro Saletti The occurrence of optic pathway gliomas (OPGs) in children with neurofibromatosis...
Cancers, Vol. 11, Pages 1839: Targeting Calcium Signalling in Malignant Mesothelioma Cancers doi: 10.3390/cancers11121839 Authors: Martinotti Patrone Moccia Ranzato Calcium ions (Ca2+) are central in cancer development and growth, serving as a major signaling system determining the cell's fate. Therefore, the investigation of the functional roles of ion channels in cancer development may identify novel approaches for determining tumor prognosis. Malignant mesothelioma is...
Cancers, Vol. 11, Pages 1837: Changes of O6-Methylguanine DNA Methyltransferase (MGMT) Promoter Methylation in Glioblastoma Relapse—A Meta-Analysis Type Literature Review Cancers doi: 10.3390/cancers11121837 Authors: Feldheim Kessler Monoranu Ernestus Löhr Hagemann Methylation of the O6-methylguanine DNA methyltransferase (MGMT) promoter has emerged as strong prognostic factor in the therapy of glioblastoma multiforme. It is associated with an improved response to...
Cancers, Vol. 11, Pages 1832: Targeting STAT3 and STAT5 in Tumor-Associated Immune Cells to Improve Immunotherapy Cancers doi: 10.3390/cancers11121832 Authors: Verdeil Lawrence Schmitt-Verhulst Auphan-Anezin Oncogene-induced STAT3-activation is central to tumor progression by promoting cancer cell expression of pro-angiogenic and immunosuppressive factors. STAT3 is also activated in infiltrating immune cells including tumor-associated macrophages (TAM) amplifying immune...
Cancers, Vol. 11, Pages 1835: Role of the YAP-1 Transcriptional Target cIAP2 in the Differential Susceptibility to Chemotherapy of Non-Small-Cell Lung Cancer (NSCLC) Patients with Tumor RASSF1A Gene Methylation from the Phase 3 IFCT-0002 Trial Cancers doi: 10.3390/cancers11121835 Authors: Dubois Keller Hoflack Maille Antoine Westeel Bergot Quoix Lavolé Bigay-Game Pujol Langlais Morin Zalcman Levallet RASSF1 gene methylation predicts...
Cancers, Vol. 11, Pages 1833: JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL Cancers doi: 10.3390/cancers11121833 Authors: Wahnschaffe Braun Timonen Giri Schrader Wagle Almusa Johansson Bellanger López Haferlach Stern Dürig Siebert Mustjoki Aittokallio Herling T-cell prolymphocytic leukemia (T-PLL) is a rare and poor-prognostic mature T-cell leukemia. Recent studies detected genomic aberrations affecting...
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