Related ArticlesCharacterization of long non-coding RNA and messenger RNA profiles in laryngeal cancer by weighted gene co-expression network analysis. Aging (Albany NY). 2019 Nov 18;11: Authors: Liu H, Sun Y, Tian H, Xiao X, Zhang J, Wang Y, Yu F Abstract Laryngeal cancer (LC) is a malignant tumor in the head and neck region. It was recently elucidated that long non-coding RNAs (lncRNAs) participate in the pathogenesis of LC. However, the detailed mechanism...
Tue Nov 19, 2019 14:23
Related ArticlesPatterns of failure and outcomes in cT4 Oral squamous cell carcinoma (OSCC) undergoing upfront surgery in comparison to Neo-Adjuvant Chemotherapy (NACT) followed by surgery: A Matched Pair analysis. Oral Oncol. 2019 Nov 15;100:104455 Authors: Thiagarajan S, Dhar H, Bhattacharjee A, Fatehi KS, Shah SB, Chaukar D, Nair D, Deshmukh A, Prabhash K, Joshi A, Patil V, Noronha V, Laskar SG, Cruz AKD PMID: 31739192 [PubMed - as supplied by publisher]
Tue Nov 19, 2019 14:23
Related ArticlesImmunotherapy in head and neck cancer: The great challenge of patient selection. Crit Rev Oncol Hematol. 2019 Nov 03;144:102829 Authors: Napolitano M, Schipilliti FM, Trudu L, Bertolini F Abstract The development of immune checkpoint inhibitors (ICIs) revolutionized the therapeutic landscape in head and neck cancer. However, the majority of patients present primary resistance to ICIs and do not benefit from use of these agents, highlighting...
Tue Nov 19, 2019 14:23
Related ArticlesNasal glial heterotopia in children: Two case reports and literature review. Int J Pediatr Otorhinolaryngol. 2019 Oct 15;129:109728 Authors: Yan YY, Zhou ZY, Bi J, Fu Y Abstract Nasal glial heterotopia is a rare developmental anomaly. We present two cases of nasal glial heterotopia. The presenting symptoms, imaging findings, treatment, histological appearance, and follow-up are described in detail. We additionally reviewed all pediatric...
Tue Nov 19, 2019 14:23
Activated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair.
Related ArticlesActivated neutrophils exert myeloid-derived suppressor cell activity damaging T cells beyond repair. Blood Adv. 2019 Nov 26;3(22):3562-3574 Authors: Aarts CEM, Hiemstra IH, Béguin EP, Hoogendijk AJ, Bouchmal S, van Houdt M, Tool ATJ, Mul E, Jansen MH, Janssen H, van Alphen FPJ, de Boer JP, Zuur CL, Meijer AB, van den Berg TK, Kuijpers TW Abstract Myeloid-derived suppressor cells (MDSCs) have the capacity to suppress T-cell-mediated immune...
Tue Nov 19, 2019 14:23
Related ArticlesTransoral robotic surgery in the management of head and neck squamous cell cancer with unknown primary. Acta Otolaryngol. 2019 Nov 18;:1-4 Authors: Nilsson JS, Wahlberg P, Greiff L Abstract Background: Transoral robotic surgery (TORS) assisted base of the tongue (BOT) resection has been suggested as part of the work-up for head and neck squamous cell cancer with unknown primary (HNSCC-CUP). Success rates vary with regard to identification...
Tue Nov 19, 2019 14:23
Related ArticlesDoes age or frailty have more predictive effect on outcomes following pedicled flap reconstruction? An analysis of 44,986 cases†. J Plast Surg Hand Surg. 2019 Nov 18;:1-10 Authors: Cuccolo NG, Sparenberg S, Ibrahim AMS, Crystal DT, Blankensteijn LL, Lin SJ Abstract The elderly population in the United States is expanding rapidly, and with advancements in modern medicine, the number of elderly patients undergoing surgery has risen in parallel....
Tue Nov 19, 2019 14:23
Related ArticlesImpact of posterior septum resection on nasal airflow pattern and warming function. Acta Otolaryngol. 2019 Nov 18;:1-7 Authors: Li L, London NR, Zang H, Han D Abstract Background: The functional significance of the posterior segment of the septum is not fully understood.Aims/Objectives: The purpose of this study was to evaluate the impact of posterior septum resection with varying extents on nasal airflow pattern and warming function,...
Tue Nov 19, 2019 14:23
Related ArticlesEpstein-Barr virus molecular epidemiology and variants identification in head and neck squamous cell carcinoma. Eur J Cancer Prev. 2019 Nov 14;: Authors: Karbalaie Niya MH, Safarnezhad Tameshkel F, Keyvani H, Esghaei M, Panahi M, Zamani F, Tabibzadeh A Abstract Epstein-Barr virus (EBV) is known as one of the most widespread oncogenic viruses. Head and neck squamous cell carcinoma (HNSCC) is triggered by various risk factors. The aim of...
Tue Nov 19, 2019 14:23
Related ArticlesManagement of unilateral head and neck carcinoma of unknown primary: Retrospective analysis of the impact of postoperative radiotherapy target volumes. Head Neck. 2019 Nov 18;: Authors: Podeur F, Pommier P, Crozes C, Monchet E, Ton Van J, Roux PE, Poupart M, Zrounba P, Julieron M, Deneuve S Abstract BACKGROUND: We compared the outcome of postoperative unilateral cervical nodes radiotherapy (UL-RT) vs bilateral cervical nodes plus total...
Tue Nov 19, 2019 14:23
Related ArticlesViral IL-10 promotes cell proliferation and cell cycle progression via JAK2/STAT3 signaling pathway in nasopharyngeal carcinoma cells. Biotechnol Appl Biochem. 2019 Nov 18;: Authors: Ren Y, Yang J, Li M, Huang N, Chen Y, Wu X, Wang X, Qiu S, Wang H, Li X Abstract Epstein Barr Virus (EBV) is positively related to the morbidity of nasopharyngeal carcinoma (NPC) in Asia. After infection, EBV can produce several proteins, including viral...
Tue Nov 19, 2019 14:23
Related ArticlesEffects of the relative positioning between the disc-fovea angle and localized optic disc defects on the 10-2 visual field results in glaucoma. Ophthalmol Glaucoma. 2018 Nov-Dec;1(3):175-181 Authors: Matos AG, De Moraes CG, Pinto TT, Silva MJL, Paula JS Abstract Purpose: To investigate the effects of the foveal position relative to the optic disc on the 10-2 visual field (VF) results of glaucoma patients with localized inferotemporal...
Tue Nov 19, 2019 14:23
Related ArticlesThe association between oral candidiasis and severity of chemoradiotherapy-induced dysphagia in head and neck cancer patients: A retrospective cohort study. Clin Transl Radiat Oncol. 2020 Jan;20:13-18 Authors: Saito H, Shodo R, Yamazaki K, Katsura K, Ueki Y, Nakano T, Oshikane T, Yamana N, Tanabe S, Utsunomiya S, Ohta A, Abe E, Kaidu M, Sasamoto R, Aoyama H Abstract Background and purpose: Concurrent chemoradiotherapy (CCRT) for head...
Tue Nov 19, 2019 14:23
Related ArticlesAtypical presentations of parathyroid gland pathology: A pictorial review. Eur J Radiol Open. 2019;6:320-329 Authors: Kowa XY, Richards P, Waterhouse M, Parvanta L, Adams A Abstract Primary hyperparathyroidism is associated with significant morbidity and mortality. It is in this day and age, an eminently treatable condition which relies heavily on preoperative imaging to localise enlarged parathyroid glands. The imaging appearances of...
Tue Nov 19, 2019 14:23
Related ArticlesQuantitative Spatial Analysis of Metabolic Heterogeneity Across in vivo and in vitro Tumor Models. Front Oncol. 2019;9:1144 Authors: Heaster TM, Landman BA, Skala MC Abstract Metabolic preferences of tumor cells vary within a single tumor, contributing to tumor heterogeneity, drug resistance, and patient relapse. However, the relationship between tumor treatment response and metabolically distinct tumor cell populations is not well-understood....
Tue Nov 19, 2019 14:23
Related ArticlesHuman Papillomavirus Related Multiphenotypic Sinonasal Carcinoma: Report of a Case with Early and Progressive Metastatic Disease. J Neurol Surg Rep. 2019 Oct;80(4):e41-e43 Authors: Rodarte AI, Parikh AS, Gadkaree SK, Lehmann AE, Faquin WC, Holbrook EH, Lin DT Abstract Introduction Human papillomavirus (HPV) related multiphenotypic sinonasal carcinoma (HMSC) is a newly described entity. The prognosis of this neoplasm is not well understood,...
Tue Nov 19, 2019 14:23
Related ArticlesHow to Manage Disfiguring Scars in Involuted Infantile Hemangioma. Adv Wound Care (New Rochelle). 2019 Jun 01;8(6):221-229 Authors: Yuzuriha S, Nagai F, Noguchi M Abstract Objective: No active treatment is required in the majority of cases of infantile hemangioma (IH), while they proliferate and involute without sequelae. However, ulceration, bleeding, or destruction/obstruction of important structures may occur in 10% of cases during...
Tue Nov 19, 2019 14:23
Related ArticlesLong non-coding RNA LINC00460 promotes head and neck squamous cell carcinoma cell progression by sponging miR-612 to up-regulate AKT2. Am J Transl Res. 2019;11(10):6326-6340 Authors: Xie X, Xiong G, Wang Q, Ge Y, Cui X Abstract LncRNAs (long noncoding RNAs) have been shown to be potentially critical regulators in head and neck squamous cell carcinoma (HNSCC). LncRNA LINC00460 (long intergenic non-protein coding RNA 460), an "oncogene",...
Tue Nov 19, 2019 14:23
Related ArticlesTreating Clinically Node-Negative Insular Thyroid Carcinoma without Prophylactic Central Compartment Neck Dissection Is Associated with Decreased Survival Regardless of T Staging and Administration of Radioactive Iodine Therapy: The First Evidence. Int J Endocrinol. 2019;2019:3078012 Authors: Yu PC, Shi X, Ma B, Li CW, Tan LC, Hu WP, Wang Y, Wei WJ, Wang YL, Ji QH Abstract For the rare but aggressive insular thyroid carcinoma (ITC), there's...
Tue Nov 19, 2019 14:23
Related ArticlesRegulation of Neural Stem Cell Proliferation and Differentiation by Graphene-Based Biomaterials. Neural Plast. 2019;2019:3608386 Authors: Xia L, Zhu W, Wang Y, He S, Chai R Abstract The transplantation of neural stem cells (NSCs) has become an emerging treatment for neural degeneration. A key factor in such treatments is to manipulate NSC behaviors such as proliferation and differentiation, resulting in the eventual regulation of NSC...
Tue Nov 19, 2019 14:23
Related ArticlesThe Effect of Mindfulness-Based Interventions on Tinnitus Distress. A Systematic Review. Front Neurol. 2019;10:1135 Authors: Rademaker MM, Stegeman I, Ho-Kang-You KE, Stokroos RJ, Smit AL Abstract Objectives: With this systematic review we aim to provide an overview of the evidence of the effect of Mindfulness Based Interventions (MBIs) on (1) tinnitus distress and (2) anxiety and/or depression in tinnitus patients. Methods: We conducted...
Tue Nov 19, 2019 14:23
Related ArticlesDye Tracking Following Posterior Semicircular Canal or Round Window Membrane Injections Suggests a Role for the Cochlea Aqueduct in Modulating Distribution. Front Cell Neurosci. 2019;13:471 Authors: Talaei S, Schnee ME, Aaron KA, Ricci AJ Abstract The inner ear houses the sensory epithelium responsible for vestibular and auditory function. The sensory epithelia are driven by pressure and vibration of the fluid filled structures in which...
Tue Nov 19, 2019 14:23
Related Articles[Verification results of objective newborn hearing screening]. Orv Hetil. 2019 Nov;160(47):1850-1855 Authors: Gáborján A, Götze J, Küstel M, Kecskeméti N, Baranyi I, Csontos F, Tamás L Abstract Sufficient hearing is the cornerstone of the development of children's complex sensory perception, sound recognition, speech development and optimal communication skills. Hearing screening of newborns is necessary to detect congenital hearing disorders....
Tue Nov 19, 2019 14:23
Related ArticlesDifficulty envisioning a positive future: Secondary analyses in patients in intensive care who are communication vulnerable. Nurs Health Sci. 2019 Nov 18;: Authors: Koszalinski RS, Heidel RE, McCarthy J Abstract The purpose of this study was to report a secondary analysis of data collected through a primary study. The primary study was a, randomized, control trial that used a team-designed (nursing, speech language hearing, engineering,...
Tue Nov 19, 2019 13:23
Related ArticlesA clinical, pathological and immunohistochemical series of 9 cases of primary cutaneous apocrine carcinomas of the head and neck. Australas J Dermatol. 2019 Nov 17;: Authors: Portelli F, Salvati L, Projetto E, Gori A, Scarfì F, Trane L, Lo Russo G, Innocenti A, De Giorgi V Abstract BACKGROUND/OBJECTIVES: Primary cutaneous apocrine carcinoma is a rare malignant adnexal skin tumour that can recur locally, spread to regional lymph nodes...
Tue Nov 19, 2019 13:23
Related ArticlesEffects of low-temperature plasma treatment on pulmonary function in children with obstructive sleep apnea-hypopnea syndrome. Ir J Med Sci. 2019 Nov 18;: Authors: Wang X, Liu Y, Tang G, Wang H, Zhao Y Abstract BACKGROUND: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a common sleep-related respiratory disease. Despite reports of low-temperature plasma radiofrequency ablation of tonsils and adenoids for the treatment of OSAHS, the...
Tue Nov 19, 2019 13:23
Related ArticlesPort-Site Implantation Diagnosed by Iodine-131 Post-Ablation Single-Photon Emission Tomography-Computed Tomography After Robotic Thyroidectomy: A Case Report. Am J Case Rep. 2019 Nov 18;20:1695-1698 Authors: Kim MR, Jo S, Shim HK Abstract BACKGROUND Robotic thyroidectomy using remote access approaches is currently regarded as the optimal surgical protocol for highly selected patients. This approach has excellent cosmetic outcomes compared...
Tue Nov 19, 2019 13:23
Related ArticlesInvestigation of vitamin D levels in patients with Sudden Sensory-Neural Hearing Loss and its effect on treatment. Am J Otolaryngol. 2019 Nov 12;:102327 Authors: Ghazavi H, Kargoshai AA, Jamshidi-Koohsari M Abstract BACKGROUND: Due to high prevalence of vitamin D deficiency and the possible association with Sudden Sensory-Neural Hearing Loss (SSNHL) finding the main causes and appropriate treatments are highly essential. This study aimed...
Tue Nov 19, 2019 13:23
Related ArticlesCerumen impaction was composed of abnormal exfoliation of keratinocytes that was correlated with infection. Am J Otolaryngol. 2019 Nov 07;:102340 Authors: Zhang S, Jin M, Zhou G, Zhang Y Abstract OBJECTIVE: This study investigated the exact composition and tried to be helpful in explaining the etiologic mechanism of cerumen impaction in the external auditory canal (EAC). METHODS: A hundred impacted cerumen samples and 15 normal...
Tue Nov 19, 2019 13:23
Related ArticlesDiagnosis, Staging, Radiation Treatment Response Assessment, and Outcome Prognostication of Head and Neck Cancers Using PET Imaging: A Systematic Review. PET Clin. 2020 Jan;15(1):65-75 Authors: Hohenstein NA, Chan JW, Wu SY, Tahir P, Yom SS Abstract This systematic review summarizes the current applications of 18F-FDG PET imaging in the diagnosis, staging, radiation treatment response assessment, and outcome prognostication of head and...
Tue Nov 19, 2019 13:23
Related ArticlesTranexamic acid has no advantage in head and neck surgical procedures: a randomised, double-blind, controlled clinical trial. J Laryngol Otol. 2019 Nov 18;:1-9 Authors: Thakur A, Gupta S, Thakur JS, Minhas RS, Azad RK, Vasanthalakshmi MS, Sharma DR, Mohindroo NK Abstract OBJECTIVE: To assess the effect of tranexamic acid in head and neck surgical procedures. METHODS: A prospective, double-blind and randomised, parallel group,...
Tue Nov 19, 2019 13:23
Related ArticlesReliability of diffusion-weighted magnetic resonance imaging in differentiation of recurrent cholesteatoma and granulation tissue after intact canal wall mastoidectomy. J Laryngol Otol. 2019 Nov 18;:1-4 Authors: Allam HS, Abdel Razek AAK, Ashraf B, Khalek M Abstract OBJECTIVE: To assess the reliability of diffusion-weighted magnetic resonance imaging in differentiating recurrent cholesteatoma from granulation tissue after intact canal...
Tue Nov 19, 2019 13:23
Related ArticlesCanal wall down mastoidectomy with obliteration versus canal wall up mastoidectomy in primary cholesteatoma surgery. J Laryngol Otol. 2019 Nov 18;:1-5 Authors: Wilkie MD, Chudek D, Webb CJ, Panarese A, Banhegyi G Abstract OBJECTIVE: This study sought to compare disease recidivism rates between canal wall up mastoidectomy and a canal wall down with obliteration technique. METHODS: Patients undergoing primary cholesteatoma surgery...
Tue Nov 19, 2019 13:23
Related ArticlesPrevalence of Intracranial Aneurysms in Patients With Systemic Vessel Aneurysms: A Nationwide Cohort Study. Stroke. 2019 Nov 18;:STROKEAHA119027285 Authors: Song J, Lim YC, Ko I, Kim JY, Kim DK Abstract Background and Purpose- Most aneurysms are a focal manifestation of a systemic condition. Some reports have suggested genetic and environmental factors may play a role in pathogenesis. The aim of the present study was to evaluate the prevalence...
Tue Nov 19, 2019 13:23
Related ArticlesIdentifying Disadvantaged Groups for Cochlear Implantation: Demographics from a Large Cochlear Implant Program. Ann Otol Rhinol Laryngol. 2019 Nov 18;:3489419888232 Authors: Tolisano AM, Schauwecker N, Baumgart B, Whitson J, Kutz JW, Isaacson B, Hunter JB Abstract OBJECTIVE: To identify demographic predictors of patients undergoing cochlear implantation evaluation and surgery. METHODS: Consecutive adult patients between 2009...
Tue Nov 19, 2019 13:23
Related ArticlesA single-arm, phase 2 study of steroid-containing mouthwash for the prevention of everolimus-associated stomatitis in multiple tumor types. Int J Clin Oncol. 2019 Oct;24(10):1320-1327 Authors: Hattori M, Hagiwara S, Kotani H, Tatematsu M, Tachi M, Hijioka S, Shimizu J, Andoh M, Mizuno Y, Sawaki M, Yoshimura A, Gondo N, Adachi Y, Yoshimura K, Iwata H Abstract BACKGROUND: Everolimus is a mammalian target of rapamycin inhibitor used in...
Tue Nov 19, 2019 13:23
Related ArticlesCharacterizing Decisional Conflict for Caregivers of Children With Obstructive Sleep Apnea Without Tonsillar Hypertrophy. J Clin Sleep Med. 2018 05 15;14(5):849-855 Authors: Manning AM, Duggins AL, Tiemeyer KA, Mullen LA, Crisalli JA, Cohen AP, Ishman SL Abstract STUDY OBJECTIVES: The goals of this study were to (1) evaluate the degree of decisional conflict (DC) experienced by caregivers of children with obstructive sleep apnea (OSA)...
Tue Nov 19, 2019 13:23
Related ArticlesObstructive Sleep Apnea is an Independent Risk Factor for Hospital Readmission. J Clin Sleep Med. 2018 05 15;14(5):753-758 Authors: Scalzitti NJ, O'Connor PD, Nielsen SW, Aden JK, Brock MS, Taylor DM, Mysliwiec V, Dion GR Abstract STUDY OBJECTIVES: Hospital readmissions are an important metric of quality and safety. This study seeks to characterize the relationship between readmissions and obstructive sleep apnea (OSA). A better understanding...
Tue Nov 19, 2019 13:23
Related ArticlesSleep Disorders and Their Management in Children With Ehlers-Danlos Syndrome Referred to Sleep Clinics. J Clin Sleep Med. 2018 04 15;14(4):623-629 Authors: Domany KA, Hantragool S, Smith DF, Xu Y, Hossain M, Simakajornboon N Abstract STUDY OBJECTIVES: The nature of sleep disorders in children with Ehlers-Danlos syndrome (EDS) is unknown. We aimed to describe the type, the management, and the short-term outcome of sleep disorders in...
Tue Nov 19, 2019 13:23
Related ArticlesEvaluation of a Trial Period With a Sleep Position Trainer in Patients With Positional Sleep Apnea. J Clin Sleep Med. 2018 04 15;14(4):575-583 Authors: Beyers J, Dieltjens M, Kastoer C, Opdebeeck L, Boudewyns AN, De Volder I, Van Gastel A, Verbraecken JA, De Backer WA, Braem MJ, Van de Heyning PH, Vanderveken OM Abstract STUDY OBJECTIVES: To assess the overall clinical effectiveness of a sleep position trainer (SPT) in patients with...
Tue Nov 19, 2019 13:23
Related ArticlesIntegrating the Divided Nasal Cannula Into Routine Polysomnography to Assess Nasal Cycle: Feasibility and Effect on Outcomes. J Clin Sleep Med. 2018 04 15;14(4):641-650 Authors: Scapuccin M, Schneider L, Rashid N, Zaghi S, Rosa T, Tsou YA, Liu S, Lazarini P, Capasso R, Ruoff C Abstract STUDY OBJECTIVES: Patients suspected to have sleep-disordered breathing underwent an overnight polysomnography using a divided nasal cannula to gain...
Tue Nov 19, 2019 13:23
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