Correlation between Type of Clefting and the Incidence of Otitis Media among Children with Lip and/or Palate Clefts. ORL J Otorhinolaryngol Relat Spec. 2019 Nov 13;:1-10 Authors: Mangia LRL, Tramontina B, Tonocchi R, Polanski JF Abstract INTRODUCTION: Otitis media is a frequent condition among children with high morbidity. Orofacial clefts are undoubtedly one of the most well-established risk factors for otitis media during childhood. The clinical spectrum...
Thu Nov 14, 2019 17:18
Synthesis of Zinc oxide nanoparticles from Marsdenia tenacissima inhibits the cell proliferation and induces apoptosis in laryngeal cancer cells (Hep-2). J Photochem Photobiol B. 2019 Sep 12;201:111624 Authors: Wang Y, Zhang Y, Guo Y, Lu J, Veeraraghavan VP, Mohan SK, Wang C, Yu X Abstract Biosynthesis of Zinc oxide nanoparticles (ZnONPs) from natural plants stands as a promising nanodrug delivery system in cancer therapeutics. Marsdenia tenacissima...
Thu Nov 14, 2019 17:18
Acute Upper Airway Obstruction. N Engl J Med. 2019 Nov 14;381(20):1940-1949 Authors: Eskander A, de Almeida JR, Irish JC PMID: 31722154 [PubMed - in process]
Thu Nov 14, 2019 17:18
Rising incidence of late-stage head and neck cancer in the United States. Cancer. 2019 Nov 13;: Authors: Thompson-Harvey A, Yetukuri M, Hansen AR, Simpson MC, Adjei Boakye E, Varvares MA, Osazuwa-Peters N Abstract BACKGROUND: The current study was conducted to determine whether the incidence of late-stage head and neck cancer (HNC) is decreasing and to estimate the risk of late-stage HNC diagnosis based on race and sex. METHODS: Age-adjusted...
Thu Nov 14, 2019 17:18
Is tailored management better than salvage in laryngeal squamous cell carcinomas. Head Neck. 2019 Nov 12;: Authors: Ilapakruty B, Rao VUS PMID: 31722118 [PubMed - as supplied by publisher]
Thu Nov 14, 2019 17:18
Age at Full-Time Use Predicts Language Outcomes Better Than Age of Surgery in Children Who Use Cochlear Implants. Am J Audiol. 2019 Nov 13;:1-7 Authors: Park LR, Gagnon EB, Thompson E, Brown KD Abstract Purpose The aims of this study were to (a) determine a metric for describing full-time use (FTU), (b) establish whether age at FTU in children with cochlear implants (CIs) predicts language at 3 years of age better than age at surgery, and (c) describe...
Thu Nov 14, 2019 17:18
[Bioinformatics analysis of programmed cell death ligand 1 co-expression genes and their regulatory network in head and neck squamous cell carcinoma]. Hua Xi Kou Qiang Yi Xue Za Zhi. 2019 Oct 01;37(5):516-520 Authors: Yang LS, Shi CY, Liang YH, Liu T, Hou XR, Tian XD, Wang XY Abstract OBJECTIVE: This study aimed to construct a network of programmed celldeath ligand 1 (PD-L1) co-expression genes and screen potential biomarkers for PD-L1 expression in...
Thu Nov 14, 2019 17:18
New landmarks in endonasal surgery: from nasal bone to anterior cribriform plate including branches of anterior ethmoidal artery and nerve and terminal nerve. Int Forum Allergy Rhinol. 2019 Nov 13;: Authors: Roussel LM, Patron V, Maubert E, Escalard C, Goux D, Beaudouin V, Lechapt E, Moreau S, Hitier M Abstract BACKGROUND: Despite the development of anterior skull base surgery, the anatomy of the nasal bone and anterior cribriform plate remains unclear....
Thu Nov 14, 2019 17:18
Reply to the letter of the editor: Is tailored management better than salvage in laryngeal squamous cell carcinomas? Head Neck. 2019 Nov 12;: Authors: Mimica X, Hanson M, Cohen MA PMID: 31721377 [PubMed - as supplied by publisher]
Thu Nov 14, 2019 17:18
TRPV1 regulates inflammatory process in the tongue of surgically induced xerostomia mouse. Head Neck. 2019 Nov 13;: Authors: Yoo MH, Rhee YH, Jung J, Lee SJ, Moon JH, Mo JH, Chung PS Abstract BACKGROUND: The aim of study is to investigate the role of transient receptor potential cation channel subfamily V member 1 (TRPV1) on xerostomia-induced inflammatory response in vivo. METHODS: Parotid, submandibular, and lingual gland were removed for...
Thu Nov 14, 2019 17:18
Pollen season is reflected on symptom load for grass and birch pollen-induced allergic rhinitis in different geographic areas - an EAACI Task Force Report. Allergy. 2019 Nov 13;: Authors: Pfaar O, Karatzas K, Bastl K, Berger U, Buters J, Darsow U, Demoly P, Durham SR, Galán C, Gehrig R, Gerth van Wijk R, Jacobsen L, Katsifarakis N, Klimek L, Saarto A, Sofiev M, Thibaudon M, Werchan B, Bergmann KC Abstract BACKGROUND: The effectiveness of allergen immunotherapy...
Thu Nov 14, 2019 17:18
Tumor Volume Useful Beyond Classic Criteria in Selecting Larynx Cancers For Preservation Therapy. Laryngoscope. 2019 Nov 13;: Authors: Sharrett JM, Ward MC, Murray E, Scharpf J, Lamarre ED, Prendes BL, Lorenz RR, Burkey BB, Koyfman SA, Woody NM, Greskovich JF, Adelstein DJ, Geiger JL, Joshi NP Abstract OBJECTIVE: To investigate the association between tumor volume and locoregional failure (LRF) after concurrent chemoradiation (CCRT) for locally advanced...
Thu Nov 14, 2019 17:18
The prognostic value of anterior commissure involvement in T1 glottic cancer: A systematic review and meta-analysis. Laryngoscope. 2019 Nov 13;: Authors: Tulli M, Re M, Bondi S, Ferrante L, Dajko M, Giordano L, Gioacchini FM, Galli A, Bussi M Abstract OBJECTIVE: The anterior commissure is considered a laryngeal subsite, but it is not taken into account in the current T-staging system. The impact of anterior commissure involvement (ACI) on the oncologic...
Thu Nov 14, 2019 17:18
Adverse respiratory outcomes among head and neck cancer survivors in the Utah Cancer Survivors Study. Cancer. 2019 Nov 13;: Authors: Kawakita D, Abdelaziz S, Chen Y, Rowe K, Snyder J, Fraser A, Smith K, Herget K, Deshmukh V, Newman M, Monroe M, Hashibe M Abstract BACKGROUND: The number of head and neck cancer (HNC) survivors has been increasing because of improving survival in the United States. The aim of this study was to evaluate the incidence of...
Thu Nov 14, 2019 17:18
A novel splice variant of LOXL2 promotes progression of human papillomavirus-negative head and neck squamous cell carcinoma. Cancer. 2019 Nov 13;: Authors: Liu C, Guo T, Sakai A, Ren S, Fukusumi T, Ando M, Sadat S, Saito Y, Califano JA Abstract BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is one of the most frequently diagnosed cancers worldwide. LOX-like (LOXL) 2 (LOXL2) demonstrates alternative splicing events in patients with human papillomavirus...
Thu Nov 14, 2019 17:18
PD-L1 CPS Scoring Accuracy in Small Biopsies and Aspirate Cell Blocks from Patients with Head and Neck Squamous Cell Carcinoma. Head Neck Pathol. 2019 Nov 13;: Authors: Paintal AS, Brockstein BE Abstract To evaluate the performance characteristics of PD-L1 immunohistochemistry (IHC) combined positive scoring (CPS) in core biopsies and aspirate cell blocks from patients with head and neck squamous cell carcinoma (HNSqCCa). PD-L1 IHC using the SP263 antibody...
Thu Nov 14, 2019 17:18
High nodal FDG uptake increases risk of distant metastasis in patients with oropharyngeal squamous cell carcinoma. Eur J Nucl Med Mol Imaging. 2019 Nov 13;: Authors: Jensen JS, Christensen JT, Håkansson K, Zamani M, Vogelius IR, Löfgren J, Fischer BM, Friborg J, von Buchwald C, Rasmussen JH Abstract BACKGROUND: The purpose of this study was to investigate if FDG uptake metrics in primary tumor and lymph node metastases in patients with oropharyngeal...
Thu Nov 14, 2019 17:18
[Laryngectomy-still state of the art?] HNO. 2019 Nov 12;: Authors: Vahl JM, Schuler PJ, Greve J, Laban S, Knopf A, Hoffmann TK Abstract Total laryngectomy provides a curative approach for patients with advanced laryngeal and hypopharyngeal cancer without distant metastasis. Especially in stage cT4a disease, laryngectomy is superior to primary radio(chemo)therapy in retrospective studies. Further relevant indications for the procedure are tumor-related...
Thu Nov 14, 2019 17:18
Analysis of Patients Diagnosed with Benign Paroxysmal Positional Vertigo and the Corresponding Incidence and Patterns of Electric Toothbrush Use. Cureus. 2019 Sep 19;11(9):e5697 Authors: Sayal NR, Cox EL, Foster N, Globerson M, Farrugia M Abstract Objective To investigate whether mechanical vibrational energy from using an electric toothbrush may cause an increase in the incidence of benign paroxysmal positional vertigo (BPPV) and prevent successful...
Thu Nov 14, 2019 17:18
Development and validation of a m6A RNA methylation regulators-based signature for predicting the prognosis of head and neck squamous cell carcinoma. Am J Cancer Res. 2019;9(10):2156-2169 Authors: Zhao X, Cui L Abstract Head and neck squamous cell carcinoma (HNSCC) is among the most common types of cancers that threat the public health worldwide. A growing body of evidence has demonstrated that m6A RNA methylation plays a critical role in tumorigenesis....
Thu Nov 14, 2019 17:18
Management of Life-Threatening Hemorrhage from Maxillofacial Firearm Injuries Using Foley Catheter Balloon Tamponade. Craniomaxillofac Trauma Reconstr. 2019 Dec;12(4):301-304 Authors: Jose A, Arya S, Nagori SA, Thukral H Abstract The aim of this study is to evaluate the efficacy of Foley catheter in the management of hemorrhage from penetrating maxillofacial injuries in austere environment. This retrospective cohort study evaluated all penetrating head...
Thu Nov 14, 2019 17:18
On the Court: A Comprehensive Analysis of Basketball Facial Trauma. Craniomaxillofac Trauma Reconstr. 2019 Dec;12(4):266-270 Authors: Othman S, Cohn JE, McKinnon B Abstract With basketball gradually becoming increasingly popular across the United States, it is necessary for health care providers to understand injuries associated with the sport. We aim to determine the incidence of basketball-related facial injuries and further describe their patterns...
Thu Nov 14, 2019 17:18
Dose to swallowing structures and dysphagia in head and neck Intensity Modulated Radiation Therapy - A long term prospective analysis. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):654-659 Authors: Kannan RA, Arul Ponni TR Abstract Aim: To analyse the long term swallowing function in head and neck cancer patients and correlate with the dose to midline swallowing structures. Background: The use of concurrent chemo radiation (CRT) as the present...
Thu Nov 14, 2019 17:18
Dose distribution comparison in volumetric-modulated arc therapy plans for head and neck cancers with and without an external body contour extended technique. Rep Pract Oncol Radiother. 2019 Nov-Dec;24(6):576-584 Authors: Tanaka Y, Monzen H, Matsumoto K, Inomata S, Fuse T Abstract Aim: This study compared volumetric-modulated arc therapy (VMAT) plans for head and neck cancers with and without an external body contour extended technique (EBCT). ...
Thu Nov 14, 2019 17:18
Retraction Note: Inhibition of airway inflammation in a cockroach allergen model of asthma by agonists of miRNA-33b. Sci Rep. 2019 Nov 12;9(1):16790 Authors: Niu R, Xiao X, Liu B, Li Y, Zhong Y, Ma L Abstract This article has been retracted.PMID: 31719665 [PubMed - in process]
Thu Nov 14, 2019 17:18
Mitochondrial somatic mutations and the lack of viral genomic variation in recurrent respiratory papillomatosis. Sci Rep. 2019 Nov 12;9(1):16625 Authors: Hao Y, Ruiz R, Yang L, Neto AG, Amin MR, Kelly D, Achlatis S, Roof S, Bing R, Kannan K, Brown SM, Pei Z, Branski RC Abstract Recurrent Respiratory Papillomatosis (RRP) is a rare disease of the aerodigestive tract caused by the Human Papilloma Virus (HPV) that manifests as profoundly altered phonatory...
Thu Nov 14, 2019 17:18
ZEB1/NuRD complex suppresses TBC1D2b to stimulate E-cadherin internalization and promote metastasis in lung cancer. Nat Commun. 2019 Nov 12;10(1):5125 Authors: Manshouri R, Coyaud E, Kundu ST, Peng DH, Stratton SA, Alton K, Bajaj R, Fradette JJ, Minelli R, Peoples MD, Carugo A, Chen F, Bristow C, Kovacs JJ, Barton MC, Heffernan T, Creighton CJ, Raught B, Gibbons DL Abstract Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death...
Thu Nov 14, 2019 17:18
Acellular nerve allografts in corneal neurotisation: an inappropriate choice. Br J Ophthalmol. 2019 Nov 12;: Authors: Jowett N, Pineda Ii R PMID: 31719110 [PubMed - as supplied by publisher]
Thu Nov 14, 2019 17:18
Does tonsillectomy reduce medical care visits for pharyngitis/tonsillitis in children and adults? Retrospective cohort study from Sweden. BMJ Open. 2019 Nov 11;9(11):e033817 Authors: Østvoll E, Sunnergren O, Stalfors J Abstract OBJECTIVE: To assess the effectiveness of tonsillectomy/adenotonsillectomy in reducing medical care visits for pharyngitis or tonsillitis in children and adults with chronic/recurrent tonsillitis. DESIGN: Retrospective...
Thu Nov 14, 2019 17:18
Barriers and facilitators of patient access to medical devices in Europe: A systematic literature review. Health Policy. 2019 Oct 19;: Authors: Beck A, Retèl VP, Bhairosing PA, van den Brekel M, van Harten WH Abstract A large number of medical devices (MDs) is available in Europe. Procedures for market approval and reimbursement have been adopted over recent years to promote accelerating patient access to innovative MDs. However, there remains uncertainty...
Thu Nov 14, 2019 17:18
Rare entities in head-and-neck cancer: salvage re-irradiation with carbon ions. Radiat Oncol. 2019 Nov 12;14(1):202 Authors: Held T, Windisch P, Akbaba S, Lang K, Farnia B, Liermann J, Bernhardt D, Plinkert P, Freudlsperger C, Rieken S, Herfarth K, Debus J, Adeberg S Abstract BACKGROUND: The objective of this investigation is to evaluate the outcomes and toxicity of carbon-ion re-irradiation (CIR) in patients with rare head and neck cancers (HNC). There...
Thu Nov 14, 2019 17:18
Cognition in older adults with severe to profound sensorineural hearing loss compared to peers with normal hearing for age. Int J Audiol. 2019 Nov 13;:1-9 Authors: Huber M, Roesch S, Pletzer B, Lukaschyk J, Lesinski-Schiedat A, Illg A Abstract Objective: Cognitive performance of older adults with severe to profound sensorineural hearing loss and indication for cochlear implantation was evaluated compared to peers with age appropriate hearing.Design:...
Thu Nov 14, 2019 17:18
Primary Carcinoid Tumor in the External Auditory Canal. J Pathol Transl Med. 2019 Nov 13;: Authors: Chung DH, Han KC, Kim NR Abstract A 39-year-old man visited the department of otolaryngology due to an ongoing hearing disturbance that had lasted for one year. Temporal bone computed tomography revealed soft tissue density nearly obliterating the left external auditory canal (EAC). The mass was composed of sheets of round tumor cells containing moderate...
Thu Nov 14, 2019 17:18
Conditional Reprogramming for Patient-Derived Cancer Models and Next-Generation Living Biobanks. Cells. 2019 Oct 27;8(11): Authors: Palechor-Ceron N, Krawczyk E, Dakic A, Simic V, Yuan H, Blancato J, Wang W, Hubbard F, Zheng YL, Dan H, Strome S, Cullen K, Davidson B, Deeken JF, Choudhury S, Ahn PH, Agarwal S, Zhou X, Schlegel R, Furth PA, Pan CX, Liu X Abstract Traditional cancer models including cell lines and animal models have limited applications...
Thu Nov 14, 2019 17:18
Toxicity Profiles of Fractionated Radiotherapy, Contemporary Stereotactic Radiosurgery, and Transsphenoidal Surgery in Nonfunctioning Pituitary Macroadenomas. Cancers (Basel). 2019 Oct 26;11(11): Authors: Chang CL, Yuan KS, Wu ATH, Wu SY Abstract BACKGROUND: Here, we compared the toxicity profiles of contemporary stereotactic radiosurgery (SRS), modern fractionated radiotherapy (FRT), and transsphenoidal surgery used to treat nonfunctioning pituitary...
Thu Nov 14, 2019 17:18
Collagen Induces a More Proliferative, Migratory and Chemoresistant Phenotype in Head and Neck Cancer via DDR1. Cancers (Basel). 2019 Nov 09;11(11): Authors: Lai SL, Tan ML, Hollows RJ, Robinson M, Ibrahim M, Margielewska S, Parkinson EK, Ramanathan A, Zain RB, Mehanna H, Spruce RJ, Wei W, Chung I, Murray PG, Yap LF, Paterson IC Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide and includes squamous cell...
Thu Nov 14, 2019 17:18
Myofibroblast Gene Expression Profile after Tooth Extraction in the Rabbit. Materials (Basel). 2019 Nov 09;12(22): Authors: Marconcini S, Denaro M, Cosola S, Gabriele M, Toti P, Mijiritsky E, Proietti A, Basolo F, Giammarinaro E, Covani U Abstract After tooth extraction, the alveolar bone tends to shrink in volume, especially on the vestibular side. The role of myofibroblasts in bone remodeling has not been sufficiently investigated. The aim of the present...
Thu Nov 14, 2019 17:18
Oral Appliances in Obstructive Sleep Apnea. Healthcare (Basel). 2019 Nov 08;7(4): Authors: Dieltjens M, Vanderveken O Abstract Oral appliance therapy is increasingly prescribed as a non-invasive treatment option for patients diagnosed with obstructive sleep apnea. The custom-made titratable mandibular advancement devices (MAD) are the recommended type of oral appliances. Mandibular advancement devices are efficacious in reducing the severity of obstructive...
Thu Nov 14, 2019 17:18
Description of a cryptic new species of Cnemaspis Strauch, 1887 (Squamata: Gekkonidae) from the Western Ghats of Kerala State of India. Zootaxa. 2019 Aug 14;4656(3):zootaxa.4656.3.7 Authors: Sayyed A, Grismer LL, Campbell PD, Dileepkumar R Abstract We describe a cryptic new species of gecko of the genus Cnemaspis Strauch from the southern Western Ghats of Kerala. This medium-sized Cnemaspis species is differentiated from all other Indian congeners by...
Thu Nov 14, 2019 17:18
Related ArticlesScalp basal cell carcinoma: A different entity? Dermatol Ther. 2019 03;32(2):e12828 Authors: Castanheira A, Soares P, Boaventura P Abstract Basal cell carcinoma is the most frequent malignant neoplasm in white-skinned individuals. It develops in different body areas, including in the scalp, which is a unique anatomical region due to the high number of pilosebaceous follicles; the scalp is protected from UV exposure, a main risk factor...
Thu Nov 14, 2019 17:18
Related ArticlesOutlook and future of inner ear therapy. Hear Res. 2018 10;368:127-135 Authors: Devare J, Gubbels S, Raphael Y Abstract Drug delivery to the inner ear is an ideal method to treat a wide variety of otologic conditions. A broad range of potential applications is just beginning to be explored. New approaches combine principles of inner ear pharmacokinetics with emerging technologies of drug delivery including novel delivery systems, drug-device...
Thu Nov 14, 2019 17:18
Related ArticlesPharmacokinetic principles in the inner ear: Influence of drug properties on intratympanic applications. Hear Res. 2018 10;368:28-40 Authors: Salt AN, Plontke SK Abstract Local drug delivery to the ear has gained wide clinical acceptance, with the choice of drug and application protocol in humans largely empirically-derived. Here, we review the pharmacokinetics underlying local therapy of the ear using the drugs commonly used in clinical...
Thu Nov 14, 2019 17:18
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