Related ArticlesPneumococcus Infection of Primary Human Endothelial Cells in Constant Flow. J Vis Exp. 2019 Oct 31;(152): Authors: Jagau H, Behrens IK, Steinert M, Bergmann S Abstract Interaction of Streptococcus pneumoniae with the surface of endothelial cells is mediated in blood flow via mechanosensitive proteins such as the Von Willebrand Factor (VWF). This glycoprotein changes its molecular conformation in response to shear stress, thereby exposing...
Tue Nov 19, 2019 14:22
Related ArticlesKinetic Screening of Nuclease Activity using Nucleic Acid Probes. J Vis Exp. 2019 Nov 01;(153): Authors: Balian A, Garcia Gonzalez J, Bastida N, Akhtar KK, Borsa BA, Hernandez FJ Abstract Nucleases are a class of enzymes that break down nucleic acids by catalyzing the hydrolysis of the phosphodiester bonds that link the ribose sugars. Nucleases display a variety of vital physiological roles in prokaryotic and eukaryotic organisms, ranging...
Tue Nov 19, 2019 14:22
Related ArticlesPeptiQuick, a One-Step Incorporation of Membrane Proteins into Biotinylated Peptidiscs for Streamlined Protein Binding Assays. J Vis Exp. 2019 Nov 02;(153): Authors: Saville JW, Troman L, Duong Van Hoa F Abstract Membrane proteins, including transporters, channels, and receptors, constitute nearly one-fourth of the cellular proteome and over half of current drug targets. Yet, a major barrier to their characterization and exploitation...
Tue Nov 19, 2019 14:22
Related ArticlesImaging Dpp Release from a Drosophila Wing Disc. J Vis Exp. 2019 Oct 30;(152): Authors: George LF, Bates EA Abstract The transforming Growth Factor-beta (TGF-β) superfamily is essential for early embryonic patterning and development of adult structures in multicellular organisms. The TGF-β superfamily includes TGF-β, bone morphogenetic protein (BMPs), Activins, Growth and Differentiation Factors, and Nodals. It has long been known that...
Tue Nov 19, 2019 14:22
Related ArticlesSUMO-Binding Entities (SUBEs) as Tools for the Enrichment, Isolation, Identification, and Characterization of the SUMO Proteome in Liver Cancer. J Vis Exp. 2019 Nov 01;(153): Authors: Lopitz-Otsoa F, Delgado TC, Lachiondo-Ortega S, Azkargorta M, Elortza F, Rodríguez MS, Martínez-Chantar ML Abstract Post-translational modification is a key mechanism regulating protein homeostasis and function in eukaryotic cells. Among all ubiquitin-like...
Tue Nov 19, 2019 14:22
Related ArticlesAn Ex Vivo Tissue Culture Model of Cartilage Remodeling in Bovine Knee Explants. J Vis Exp. 2019 Nov 03;(153): Authors: Thudium CS, Engstrom A, Groen SS, Karsdal MA, Bay-Jensen AC Abstract Ex vivo culture systems cover a broad range of experiments dedicated to studying tissue and cellular function in a native setting. Cartilage is a unique tissue important for proper function of the synovial joint and is constituted by a dense extracellular...
Tue Nov 19, 2019 14:22
Related ArticlesHigh-Contrast and Fast Photorheological Switching of a Twist-Bend Nematic Liquid Crystal. J Vis Exp. 2019 Oct 31;(152): Authors: Aya S, Salamon P, Paterson DA, Storey JMD, Imrie CT, Araoka F, Jákli A, Buka Á Abstract Smart viscoelastic materials that respond to specific stimuli are one of the most attractive classes of materials important to future technologies, such as on-demand switchable adhesion technologies, actuators, molecular...
Tue Nov 19, 2019 14:22
Related ArticlesReductions in COQ2 Expression Relate to Reduced ATP Levels in Multiple System Atrophy Brain. Front Neurosci. 2019;13:1187 Authors: Hsiao JT, Purushothuman S, Jensen PH, Halliday GM, Kim WS Abstract Multiple system atrophy (MSA) is a progressive neurodegenerative disease clinically characterized by parkinsonism and cerebellar ataxia, and pathologically by oligodendrocyte α-synuclein inclusions. Genetic variants of COQ2 are associated with...
Tue Nov 19, 2019 15:17
Related ArticlesWhite Matter Language Pathways and Language Performance in Healthy Adults Across Ages. Front Neurosci. 2019;13:1185 Authors: Houston J, Allendorfer J, Nenert R, Goodman AM, Szaflarski JP Abstract The goal of this study was to determine the relationship between age-related white matter changes, with a specific focus on previously identified language pathways, and language functioning in healthy aging. 228 healthy participants (126 female;...
Tue Nov 19, 2019 15:17
Related ArticlesDiminished Frontal Theta Activity During Gaming in Young Adults With Internet Gaming Disorder. Front Neurosci. 2019;13:1183 Authors: Kim J, Park J, Park YM, Jang D, Namkoong K, Jung YC, Kim IY Abstract Cognitive control is essential for flexible, top-down, goal-directed behavior. Individuals with Internet gaming disorder (IGD) are characterized by impaired prefrontal cortex function and cognitive control. This results in an increase in...
Tue Nov 19, 2019 15:17
Related ArticlesThe Neural Basis of Herding Decisions in Enterprise Clustering: An Event-Related Potential Study. Front Neurosci. 2019;13:1175 Authors: Zhang W, Yang D, Jin J, Diao L, Ma Q Abstract Herding behavior refers to the social phenomenon in which people are intensely influenced by the decisions and behaviors of others in the same group. Although several recent studies have explored the neural basis of herding decisions in people's daily lives...
Tue Nov 19, 2019 15:17
Related ArticlesCircuit Mechanisms of Neurodegenerative Diseases: A New Frontier With Miniature Fluorescence Microscopy. Front Neurosci. 2019;13:1174 Authors: Werner CT, Williams CJ, Fermelia MR, Lin DT, Li Y Abstract Neurodegenerative diseases (NDDs), such as Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), and frontotemporal dementia (FTD), are devastating age-associated brain disorders....
Tue Nov 19, 2019 15:17
Related ArticlesA Single Dose of Methylprednisolone Improves Aversive Memory Consolidation and Extinction in Rats. Front Neurosci. 2019;13:1167 Authors: Gonçalves R, de Vargas LDS, Mello-Carpes PB Abstract Aversive memory is essential for survival, but in some situations its exacerbation can be potentially dangerous. There are several ways to modulate memory, among them, through stress-related hormones physiological release or administration of exogenous...
Tue Nov 19, 2019 15:17
Related ArticlesAstrocyte Infection Is Required for Retrovirus-Induced Spongiform Neurodegeneration Despite Suppressed Viral Protein Expression. Front Neurosci. 2019;13:1166 Authors: Cardona SM, Dunphy JM, Das AS, Lynch CR, Lynch WP Abstract The ability of retroviruses (RVs) to cause neurodegeneration is critically dependent upon two activities of the envelope protein (Env). First, Env facilitates viral genome delivery to CNS target cells through receptor...
Tue Nov 19, 2019 15:17
Related ArticlesDecoding Task-Related Functional Brain Imaging Data to Identify Developmental Disorders: The Case of Congenital Amusia. Front Neurosci. 2019;13:1165 Authors: Albouy P, Caclin A, Norman-Haignere SV, Lévêque Y, Peretz I, Tillmann B, Zatorre RJ Abstract Machine learning classification techniques are frequently applied to structural and resting-state fMRI data to identify brain-based biomarkers for developmental disorders. However, task-related...
Tue Nov 19, 2019 15:17
Related ArticlesPharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats. Front Neurosci. 2019;13:1163 Authors: Bilel S, Tirri M, Arfè R, Stopponi S, Soverchia L, Ciccocioppo R, Frisoni P, Strano-Rossi S, Miliano C, De-Giorgio F, Serpelloni G, Fantinati A, De Luca MA, Neri M, Marti M Abstract AKB48 is a designer drug belonging to the indazole synthetic cannabinoids class, illegally sold as herbal blend, incense, or research chemicals...
Tue Nov 19, 2019 15:17
Related ArticlesYour Performance Is My Concern: A Perspective-Taking Competition Task Affects ERPs to Opponent's Outcomes. Front Neurosci. 2019;13:1162 Authors: Yu H, Nan W, Yang G, Li Q, Wu H, Liu X Abstract Previous research has shown that people have more empathic responses to in-group members and more schadenfreude to out-group members. As a dimension of cognitive empathy, perspective-taking has been considered to be related to the enhancement of...
Tue Nov 19, 2019 15:17
Related ArticlesSurveillance During REM Sleep for the First-Night Effect. Front Neurosci. 2019;13:1161 Authors: Tamaki M, Sasaki Y Abstract We experience disturbed sleep in a new place, and this effect is known as the first-night effect (FNE) in sleep research. We previously demonstrated that the FNE is associated with a surveillance system in one brain hemisphere during NREM sleep, which manifests as interhemispheric asymmetry in sleep depth in the...
Tue Nov 19, 2019 15:17
Related ArticlesDynamic Metabolic Changes in the Human Thalamus at the Transition From Waking to Sleep - Insights From Simultaneous Functional MR Spectroscopy and Polysomnography. Front Neurosci. 2019;13:1158 Authors: Lehmann M, Hock A, Zoelch N, Landolt HP, Seifritz E Abstract An important contribution of the thalamus to the transition from wakefulness to sleep is a consistent finding in animal studies. In humans, only little is currently known about...
Tue Nov 19, 2019 15:17
Related ArticlesThe μDBS: Multiresolution, Directional Deep Brain Stimulation for Improved Targeting of Small Diameter Fibers. Front Neurosci. 2019;13:1152 Authors: Anderson DN, Anderson C, Lanka N, Sharma R, Butson CR, Baker BW, Dorval AD Abstract Directional deep brain stimulation (DBS) leads have recently been approved and used in patients, and growing evidence suggests that directional contacts can increase the therapeutic window by redirecting stimulation...
Tue Nov 19, 2019 15:17
Related ArticlesBAF45D Downregulation in Spinal Cord Ependymal Cells Following Spinal Cord Injury in Adult Rats and Its Potential Role in the Development of Neuronal Lesions. Front Neurosci. 2019;13:1151 Authors: Wang Z, Huang J, Liu C, Liu L, Shen Y, Shen C, Liu C Abstract The endogenous spinal cord ependymal cells (SCECs), which form the central canal (CC), are critically involved in proliferation, differentiation and migration after spinal cord injury...
Tue Nov 19, 2019 15:17
Related ArticlesProgress of Research on Exosomes in the Protection Against Ischemic Brain Injury. Front Neurosci. 2019;13:1149 Authors: Kang X, Zuo Z, Hong W, Tang H, Geng W Abstract Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20-100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological...
Tue Nov 19, 2019 15:17
Related ArticlesCharacteristics of Kinematic Parameters in Decoding Intended Reaching Movements Using Electroencephalography (EEG). Front Neurosci. 2019;13:1148 Authors: Kim H, Yoshimura N, Koike Y Abstract The utility of premovement electroencephalography (EEG) for decoding movement intention during a reaching task has been demonstrated. However, the kind of information the brain represents regarding the intended target during movement preparation remains...
Tue Nov 19, 2019 15:17
Related ArticlesAccelerated Intermittent Theta-Burst Stimulation as a Treatment for Cocaine Use Disorder: A Proof-of-Concept Study. Front Neurosci. 2019;13:1147 Authors: Steele VR, Maxwell AM, Ross TJ, Stein EA, Salmeron BJ Abstract There are no effective treatments for cocaine use disorder (CUD), a chronic, relapsing brain disease characterized by dysregulated circuits related to cue reactivity, reward processing, response inhibition, and executive...
Tue Nov 19, 2019 15:17
Related ArticlesVibrotactile Stimulation Based on the Fundamental Frequency Can Improve Melodic Contour Identification of Normal-Hearing Listeners With a 4-Channel Cochlear Implant Simulation. Front Neurosci. 2019;13:1145 Authors: Luo X, Hayes L Abstract Cochlear implant (CI) users' poor speech recognition in noise and music perception may be both due to their limited access to pitch cues such as the fundamental frequency (F0). Recent studies showed...
Tue Nov 19, 2019 15:17
Related ArticlesDietary Supplementation With the Ketogenic Diet Metabolite Beta-Hydroxybutyrate Ameliorates Post-TBI Aggression in Young-Adult Male Drosophila. Front Neurosci. 2019;13:1140 Authors: Lee DC, Vali K, Baldwin SR, Divino JN, Feliciano JL, Fequiere JR, Fernandez MA, Frageau JC, Longo FK, Madhoun SS, Mingione V P, O'Toole TR, Ruiz MG, Tanner GR Abstract Traumatic brain injury (TBI), caused by repeated concussive head trauma can induce chronic...
Tue Nov 19, 2019 15:17
Related ArticlesImpairment of Membrane Repolarization Accompanies Axon Transport Deficits in Glaucoma. Front Neurosci. 2019;13:1139 Authors: Fischer RA, Risner ML, Roux AL, Wareham LK, Sappington RM Abstract Glaucoma is a leading cause of blindness worldwide, resulting from degeneration of retinal ganglion cells (RGCs), which form the optic nerve. In glaucoma, axon transport deficits appear to precede structural degeneration of RGC axons. The period...
Tue Nov 19, 2019 15:17
Related ArticlesThe Delta-Subunit Selective GABA A Receptor Modulator, DS2, Improves Stroke Recovery via an Anti-inflammatory Mechanism. Front Neurosci. 2019;13:1133 Authors: Neumann S, Boothman-Burrell L, Gowing EK, Jacobsen TA, Ahring PK, Young SL, Sandager-Nielsen K, Clarkson AN Abstract Inflammatory processes are known to contribute to tissue damage in the central nervous system (CNS) across a broad range of neurological conditions, including stroke....
Tue Nov 19, 2019 15:17
Related ArticlesPitch Matching in Cochlear Implant Users With Single-Sided Deafness: Effects of Electrode Position and Acoustic Stimulus Type. Front Neurosci. 2019;13:1119 Authors: Adel Y, Nagel S, Weissgerber T, Baumann U, Macherey O Abstract Previous studies in patients with single-sided deafness (SSD) have reported results of pitch comparisons between electric stimulation of their cochlear implant (CI) and acoustic stimulation presented to their near-normal...
Tue Nov 19, 2019 15:17
Related ArticlesNetwork Representations of Facial and Bodily Expressions: Evidence From Multivariate Connectivity Pattern Classification. Front Neurosci. 2019;13:1111 Authors: Liang Y, Liu B, Ji J, Li X Abstract Emotions can be perceived from both facial and bodily expressions. Our previous study has found the successful decoding of facial expressions based on the functional connectivity (FC) patterns. However, the role of the FC patterns in the recognition...
Tue Nov 19, 2019 15:17
Related ArticlesCarbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation. Front Neurosci. 2019;13:1089 Authors: Elsherbiny NM, Abdel-Mottaleb Y, Elkazaz AY, Atef H, Lashine RM, Youssef AM, Ezzat W, El-Ghaiesh SH, Elshaer RE, El-Shafey M, Zaitone SA Abstract Aim: Diabetic retinopathy causes loss of vision in adults at working-age. Few therapeutic options are available...
Tue Nov 19, 2019 15:17
41 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2019/11/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Nov 19, 2019 13:18
Related ArticlesREFERENCE SURFACE FOR IN SITU GAMMA SPECTROMETRY. Radiat Prot Dosimetry. 2019 Nov 18;: Authors: Kroupa T, Setnička M, Čtvrtečková A, Marek R Abstract Chemical laboratories of the Fire Rescue Service of the Czech Republic are part of the radiation monitoring network and participate in the radiation situation monitoring in the Czech Republic. Measurements in situ are crucial for monitoring the radiation situation in emergencies associated...
Tue Nov 19, 2019 13:16
Related ArticlesRADIOACTIVE REMEDIATION OF AQUATIC ECOSYSTEMS USING MICROALGAE. Radiat Prot Dosimetry. 2019 Nov 18;: Authors: Galanda D, Tatarová D, Kuruc J, Gaálová B, Slimáková J Abstract Radionuclides that have entered the environment through nuclear weapon tests, nuclear accidents or other human activities represent an ecological hazard. Many decontamination techniques are technically and financially demanding and often not environmentally beneficial....
Tue Nov 19, 2019 13:16
Related ArticlesOCCUPATIONAL RADIATION DOSE PERFORMING HEPATOBILIARY MINIMALLY INVASIVE PROCEDURES IN CHILDREN WEIGHING LESS THAN 20 kg. Radiat Prot Dosimetry. 2019 Nov 18;: Authors: Gerasia R, Cannataci C, Maruzzelli L, Caruso C, Liotta F, Cucchiara A, Cortis K, Miraglia R Abstract Our objective is to retrospectively evaluate the effective dose (E) of operators performing pediatric Hepatobiliary Minimally Invasive Procedures (HMIP). Between October...
Tue Nov 19, 2019 13:16
46 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: upper respiratory tract infection These pubmed results were generated on 2019/11/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Tue Nov 19, 2019 13:11
Related ArticlesMiR-133a-5p inhibits androgen receptor (AR)-induced proliferation in prostate cancer cells via targeting FUsed in Sarcoma (FUS) and AR. Cancer Biol Ther. 2019 Nov 17;:1-9 Authors: Zheng L, Kang Y, Zhang L, Zou W Abstract Androgens and androgen receptors are vital factors involved in prostate cancer progression, and androgen ablation therapies are commonly employed to treat advanced prostate cancer. Previously, FUsed in Sarcoma (FUS) was...
Tue Nov 19, 2019 15:05
Related ArticlesAn interaction study of Ocimum sanctum L. and levetiracetam in pentylenetetrazole kindling model of epilepsy. J Ethnopharmacol. 2019 Nov 15;:112389 Authors: Sarangi SC, Pattnaik SS, Katyal J, Kaleekal T, Dinda AK Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Ocimum sanctum L. commonly known as tulsi (synonym of Ocimum tenuiflorum L.) is widely used in Ayurveda medicine and is having multitude neuromodulatory effect including the anticonvulsant...
Tue Nov 19, 2019 14:58
Related ArticlesClinical and genetic features in pyridoxine-dependent epilepsy: a Chinese cohort study. Dev Med Child Neurol. 2019 Nov 18;: Authors: Jiao X, Xue J, Gong P, Wu Y, Zhang Y, Jiang Y, Yang Z Abstract AIM: To characterize the clinical and genetic characteristics of a large cohort of patients with pyridoxine-dependent epilepsy (PDE). METHOD: We retrospectively collected clinical and genetic information of 33 (15 males, 18 females;...
Tue Nov 19, 2019 14:58
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