Publication date: Available online 2 September 2020Source: Acta Otorrinolaringológica EspañolaAuthor(s): Mafalda S. Barroso, Bernardo C. Araújo, João Jacinto, Catarina Marques, Ilídio Gama, Ezequiel Barros
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Publication date: Available online 2 September 2020Source: American Journal of OtolaryngologyAuthor(s): Zhengcai Lou
Publication date: Available online 2 September 2020Source: American Journal of OtolaryngologyAuthor(s): Engin Dursun, Emine Demir
Publication date: Available online 2 September 2020Source: American Journal of OtolaryngologyAuthor(s): Ozan Erol
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Publication date: Available online 3 September 2020Source: Auris Nasus LarynxAuthor(s): Natalia Yakunina, Eui-Cheol Nam
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Abstract Pharyngocutaneous fistula is a major post‐operative complication after laryngectomy and pharyngectomy surgery with potentially devastating consequences. The aim of the current study was to determine if post‐operative trend in C‐reactive protein (CRP) after laryngectomy and pharyngectomy surgery can predict pharyngocutaneous fistula. A screening test to identify those patients who healed and would not go on to develop a pharyngocutaneous fistula was defined as a 35% reduction...
Abstract Botox injections are utilised to improve pharyngoesophageal segment tonicity to improve speech and swallowing outcomes Video‐laryngoscope guided injection of Botox into the neopharynx is a easy and safe technique It is particularly useful for post‐radiotherapy patients with limited neck extension where rigid direct pharyngoscopy is impossible
Abstract Objectives the primary endpoint of this study was to evaluate the impact of bile acids on severity of laryngo‐pharyngeal reflux (LPR) and the possible correlation with esophagitis and upper airway malignancies. The second endpoint was to evaluate if salivary bile acids and molecules other than pepsin might serve as diagnostic biomarkers of LPR. Design observational prospective comparative study. Setting Otorhinolaryngology unit of a tertiary hospital. Participants 62...
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Condition: Plaque PsoriasisInterventions: Biological: Ixekizumab; Drug: Methotrexate; Drug: Cyclosporin A; Drug: AcitretinSponsors: Singapore General Hospital; Translational Immunology InstituteNot yet recruiting
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Abstract Purpose To evaluate frontal sinus complications developed after previous external craniotomies requiring frontal sinus reconstruction and their treatment with an endoscopic approach. Methods We retrospectively evaluated 22 patients who referred to Sant’Orsola-Malpighi University Hospital and Bellaria Hospital (Bologna, Italy) between 2005 and 2017....
Abstract Purpose Evaluating the effectiveness of intraoperative auditory brainstem responses (ABRs) to stimulation by the Vibrant Soundbridge (VSB) active middle ear implant for quantifying the implant’s floating mass transducer (FMT) coupling quality. Methods In a diagnostic multicentric study, patients (> 18 years) who received a VSB with different coupling...
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Abstract Psoriasis is a chronic inflammatory disease characterized by abnormal hyperproliferation and differentiation. The object of this study is to explore the role of microRNA‐215‐5p in psoriasis‐like inflammation. The expression of miR‐215‐5p was found to be down‐regulated in proinflammatory factor‐stimulated HaCaT cells and imiquimod (IMQ)‐treated skin tissues. Overexpression of miR‐215‐5p suppressed the proliferation and cell cycle progression of HaCaT cells. Further, miR‐215‐5p agomir alleviated...
Abstract In 2018, Schneider and Zouboulis analyzed the available tools for studying sebaceous gland pathophysiology in vitro. Since then, the interest in this field remains unbroken, as demonstrated by recent reviews on sebaceous gland physiology, endocrinology and neurobiology, the role of sebaceous glands beyond acne, and several original works on different areas of sebaceous gland function, including sebaceous lipogenesis. Landmark developments in the first part of the 30 years modeling research...
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Zusammenfassung Hintergrund Eine klaffende Tube kann insbesondere durch Autophonie, Druckgefühl und gestörten Höreindruck zu einer Einschränkung der Lebensqualität führen. Bei fehlenden spezifischen Symptomen kann die Diagnose der klaffenden Tube schwierig sein. Insbesondere die Abgrenzung zur chronisch obstruktiven Tubenfunktionsstörung stellt eine Herausforderung dar. Da derzeit kaum standardisierte Diagnostik- und Therapieoptionen zur...
Zusammenfassung In der klinischen Versorgung von Patienten mit obstruktiver Schlafapnoe (OSA) nehmen Fachärzte für Hals‑, Nasen- und Ohrenheilkunde eine wichtige Rolle ein, insbesondere in der ambulanten Diagnostik und in der konservativen und operativen Versorgung von Patienten mit Intoleranz gegenüber einer nächtlichen Ventilationstherapie. Während die differenzierte Indikationsstellung für operative Eingriffe und die Durchführung der notwendigen endoskopischen Zusatzdiagnostik...
Zusammenfassung Hintergrund Die chirurgische Weiterbildung wird zunehmend durch Simulatoren ergänzt. Für die ohrchirurgische Weiterbildung, hier dargestellt anhand der Mastoidektomie, stehen neben nativen Schläfenbeinen weitere Trainingsmodelle, wie das Kunststoffschläfenbein oder Computersimulatoren zur Verfügung. Ziel Es soll ein strukturiertes Weiterbildungskonzept...
Zusammenfassung Hintergrund Fehlende praktische Übungen sowie Anstieg der Studierendenzahlen führen zu der Notwendigkeit innovativer Lehrmethoden. Wir etablierten einen Diagnostik-Parcours zur Darstellung der Sinne unseres Faches. Ziel der Arbeit Das vorwiegende Ziel der Einführung des Diagnostik-Parcours war die kompakte Darstellung der Funktionsdiagnostik...
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Related Articles COVID-19 and ear endoscopy in otologic practices. Eur Arch Otorhinolaryngol. 2020 Sep 02;: Authors: Ayache S, Kutz W, Isaacson B, Badr-El-Dine M, Nogueira JF, Marchioni D, Presutti L Abstract PURPOSE: Otolaryngologists have had to postpone the majority of surgical procedures in the current COVID-19 pandemic. Airborne transmission, beyond the projection of droplets from upper airways, expose healthcare workers to a risk of viral...
Related Articles Different time course of compensation of subjective visual vertical and ocular torsion after acute unilateral vestibular lesion. Eur Arch Otorhinolaryngol. 2020 Sep 02;: Authors: Faralli M, Ricci G, Manzari L, Zambonini G, Lapenna R, Pettorossi VE Abstract PURPOSE: Time course of the recovery of otolithic dis-function caused by superior vestibular neuritis has been examined in fifteen patients. METHODS: The subjective...
Related Articles Subglottic cysts: The Great Ormond Street experience in 105 patients. Eur Arch Otorhinolaryngol. 2020 Sep 01;: Authors: Bowles PFD, Reading J, Albert D, Nash R Abstract PURPOSE: The aim of the study was to assess the contemporary presentation and management of subglottic cysts and make recommendations on the treatment of these patients. METHODS: Retrospective case series of 105 patients between October 1999 and November...
Related Articles Otolaryngological symptoms in COVID-19. Eur Arch Otorhinolaryngol. 2020 Sep 01;: Authors: Elibol E Abstract PURPOSE: The aim of this study was to evaluate the frequency of various otolaryngological symptoms in patients with COVID-19 with regard to age, gender and pneumonia-related thorax CT characteristics. METHODS: This is a retrospective study conducted between March 25, 2020 and April 25, 2020. The anamnesis and...
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This case report describes of a man in his 60s with nasopharyngeal carcinoma who underwent concurrent chemoradiotherapy and subsequently developed local recurence.
This essay highlights the lessons to be learned from the COVID-19 pandemic on the importance of recognizing communication difficulties among those with hearing impairment.
This Viewpoint examines the timing of performing tracheostomies, which are aerosol-generating procedures that may cause increased risk of COVID-19 transmission to health care workers.
This cohort study examines the association of poorer hearing with baseline and change in white matter microstructure among older adults.
Described as the “greatest global challenge for health and social care in the 21st century,” dementia is a debilitating disease that affects about 50 million individuals worldwide, a number projected to triple by 2050. Given the limited efficacy of current dementia treatments, society stands to benefit tremendously from public health prevention strategies. Hearing loss (HL) has been recently shown to be a treatable risk factor for dementia. In this issue of JAMA Otolaryngology–Head & Neck Surgery,...
This secondary analysis compares the use of objective physiological measures with subjective caregiver symptom reports to identify the association between sleep disruption with or without intermittent hypoxemia and behavior in children who underwent surgical treatment for obstructive sleep apnea.
This case report describes a man in his 20s who presented with a 4-week history of progressive swelling of the midline forehead, recurrent headache, and sinus pain, and was subsequently diagnosed with Langerhans cell histiocytosis.
This diagnostic study uses data from patients treated for oral cancer at a tertiary care cancer center in India to investigate the clinical value of a telephone-based questionnaire in detecting cancer recurrence during follow-up evaluation.
To the Editor Tay et al should be complimented on their Viewpoint “Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak” highlighting preoperative and perioperative recommendations for tracheostomy during the coronavirus disease 2019 (COVID-19) pandemic. The authors searched the literature for tracheostomies performed during the previous outbreak of severe acute respiratory syndrome (SARS), finding 3 case series...
In Reply We thank Cazzador et al for their appreciation of the Viewpoint “Surgical Considerations for Tracheostomy During the COVID-19 Pandemic: Lessons Learned From the Severe Acute Respiratory Syndrome Outbreak.” Since the publication, several other groups have also developed guidelines for tracheostomy in the context of coronavirus disease 2019 (COVID-19), with similar goals of minimizing perioperative aerosolization risks.
In the Research Letter titled, “SARS-CoV-2 Virus Isolated From the Mastoid and Middle Ear: Implications for COVID-19 Precautions During Ear Surgery,” published on July 23, 2020, funding from the National Institutes of Health was omitted. The funding and role of the funder has been added.
A 9-year-old boy presents with progressive dyspnea, snoring, dysphagia, and weight loss; biopsy and culture results revealed diffuse non-necrotizing granulomas and oropharyngeal flora with negative acid-fast bacilli and Grocott methenamine silver stains. What is your diagnosis?
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Exceptional Response to PD-1 Blockade as First-Line Therapy in Head and Neck Squamous Cell Carcinoma
The effect of PD-1 blockade as a first-line therapy in nonmetastatic head and neck squamous cell carcinoma (HNSCC) remains unknown. We report a case of an exceptional response to PD-1 blockade as a first-line therapy in a patient with HNSCC and lung cancer. A 59-year-old man presented with cheek swelling and chest pain. He was diagnosed with maxillary sinus carcinoma (squamous cell carcinoma) and lung cancer (non-small-cell lung cancer, not otherwise specified). The maxillary sinus carcinoma was...
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Abstract The scalp is a unique part of the human body and various etiological factors, such as tumour extirpation, infection, burns, or trauma, can lead to scalp defects. Primary closure, skin grafting, local flaps, tissue expansion or free tissue transfer are modalities available for scalp reconstruction. In this article, the authors share their institutional experience using various local flaps concerning the size, location, depth of defect and the quality of surrounding tissue....
Abstract To assess the parameters’ setting of the microscope during parotidectomy and the impact of microscopic parotidectomy on facial nerve functional status. A prospective study was conducted on 28 patients in a tertiary care center, who underwent microscopic parotidectomy. Microscope’s settings’ like magnification, focal length, diameter of the visualized field, and clock position were recorded. Facial nerve functional status was also recorded. All surgeries were performed...
Abstract This study was intended to assess the utility of hyaluronic acid dermal fillers in patients who do not wish surgery in addition to the patients with minor post-surgery asymmetries. This was a prospective study which included post-surgery patients for minor nasal asymmetries, patients unwilling for surgery and those waiting for revision surgery. It is of great use in candidates who do not wish surgery but had the desire for different nasal appearance especially for important...
Abstract Adenotonsillectomy is the commonest otorhinolaryngology surgery for paediatrics. The purpose of this study was to determine the safety and outcome of adenotonsillectomy in a tertiary center in Malaysia. This was achieved by studying the demographics, indications, co-morbidities of patients and its association with the complications of the procedure. This retrospective study was conducted from November 2011 until October 2016. Medical records of patients aged 2–12 years...
Abstract In patients with solitary thyroid nodules, the first course of action is to determine whether the nodule is benign or malignant. Many investigations are used to differentiate between benign and malignant nodules so as to avoid surgery in those who don’t need it. Among these, FNAC and USG are commonly used in association with clinical features but there are drawbacks of each technique. The present study was undertaken to assess the diagnostic effectivity of thyrotropin...
Abstract Acquired meatal stenosis is a difficult entity to treat with a significant recurrence rate. It is normally approached posteriorly via post aural approach and reconstructed using split thickness skin graft. We are presenting a novel method of surgery for acquired meatal stenosis using a pre auricular flap via endaural approach only. The aim was to evaluate the success rate of using a pre auricular flap in acquired atresia of the external auditory canal using the endaural...
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Publication date: Available online 3 September 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): F. Gauvrit, M. Risoud, K. Aubry, P. Bordure, A. Bozorg-Grayeli, O. Deguine, C. Eyermann, V. Franco-Vidal, B. Godey, N. Guevara, A. Karkas, N. Klopp, M. Labrousse, J.- P. Lebreton, Y. Lerosey, E. Lescanne, N. Loundon, R. Marianowski, F. Merklen, K. Mezouaghi
Publication date: Available online 3 September 2020Source: European Annals of Otorhinolaryngology, Head and Neck DiseasesAuthor(s): L. de Gabory, M. Kérimian, T. Sagardoy, A. Verdaguer, H. Gauchez
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Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Ohad Cohen, Elie Picard, Leon Joseph, Yehuda Schwartz, Jean-Yves Sichel, Pierre Attal
Publication date: November 2020Source: International Journal of Pediatric Otorhinolaryngology, Volume 138Author(s): Caroline M. Kolb, Udayan Shah, Nicole L. Aaronson
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Abstract BackgroundTraditional fracture reduction surgery cannot ensure the accuracy of the reduction while consuming the physical strength of the surgeon. Although monitoring the fracture reduction process through radiography can improve the accuracy of the reduction, it will bring radiation harm to both patients and surgeons.MethodsWe proposed a novel fracture reduction solution that parallel robot is used for fracture reduction surgery. The binocular camera indirectly obtains the position and...
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Objective To assess whether listening with two cochlear implants (bilateral) offers significant benefits in terms of speech perception over listening with one cochlear implant and one hearing aid (bimodal). Methods Retrospective review of bilateral cochlear implant recipients (24 pediatric and 26 adult). Bimodal listening was compared to bilateral listening in terms of speech perception performance at 1‐year post second implant under three listening conditions: 50 dBHL, 35 dBHL, and 50 dBHL+5...
Objective Since their development in the 1970s electronic health records (EHRs) are now nearly ubiquitous. This study aims to characterize the daily interactions of otolaryngology providers with EHRs. Methods This study was a cross‐sectional review of provider efficiency profile (PEP) data, as collected by a major EHR vendor. Participating institutions had 6 months of de‐identified PEP data reviewed starting January 1, 2019. PEP data is generated for providers with scheduled patients, both...
Objective Sleep associated hypoventilation (SAH) is diagnosed when more than 25% of total sleep time (%TST) is spent with end tidal carbon dioxide (EtCO2) > 50 mmHg. SAH in children occurs as a single entity or combined with obstructive sleep apnea. Outcomes of surgical treatment for isolated SAH in children have not been reported. Methods The medical charts of children who were diagnosed with isolated SAH and did not have OSA at a tertiary children's hospital between January 2013 and December...
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Background: An association between hearing impairment (HI) and congenital hypothyroidism (CH) has been reported previously. However, in general, studies were retrospective and had small sample sizes, and the results were variable and inconclusive. The aim of our study was to assess the prevalence of HI among patients with CH and to examine factors potentially predictive of HI including severity of CH, etiology of CH, and timing of treatment initiation. Methods: Audiometry was undertaken prospectively...
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