Antibiotics, Vol. 9, Pages 586: A New Water-Soluble Bactericidal Agent for the Treatment of Infections Caused by Gram-Positive and Gram-Negative Bacterial Strains Antibiotics doi: 10.3390/antibiotics9090586 Authors: Alessandro Presentato Elena Piacenza Antonino Scurria Lorenzo Albanese Federica Zabini Francesco Meneguzzo Domenico Nuzzo Mario Pagliaro Delia Chillura Martino Rosa Alduina Rosaria Ciriminna Grapefruit and lemon pectin obtained from the respective...
Tue Sep 08, 2020 03:00
Antibiotics, Vol. 9, Pages 587: Virulence Characteristics and Antibiotic Resistance Profiles of Shiga Toxin-Producing Escherichia coli Isolates from Diverse Sources Antibiotics doi: 10.3390/antibiotics9090587 Authors: Momna Rubab Deog-Hwan Oh Shiga toxin-producing Escherichia coli (STEC) is an enteric pathogen that causes several gastrointestinal ailments in humans across the world. STEC’s ability to cause ailment is attributed to the presence of a broad range of known and...
Tue Sep 08, 2020 03:00
Antibiotics, Vol. 9, Pages 588: Antimicrobial Resistance and Virulence of Methicillin-Resistant Staphylococcus aureus from Human, Chicken and Environmental Samples within Live Bird Markets in Three Nigerian Cities Antibiotics doi: 10.3390/antibiotics9090588 Authors: Flora Olubunmi Ogundipe Olufemi Ernest Ojo Andrea T. Feßler Dennis Hanke Olajoju Jokotola Awoyomi David Ajiboye Ojo Aderonke Kofoworola Akintokun Stefan Schwarz Sven Maurischat Background: Methicillin-resistant...
Tue Sep 08, 2020 03:00
Antibodies, Vol. 9, Pages 47: IgE Autoreactivity in Atopic Dermatitis: Paving the Road for Autoimmune Diseases? Antibodies doi: 10.3390/antib9030047 Authors: Christophe Pellefigues Atopic dermatitis (AD) is a common skin disease affecting 20% of the population beginning usually before one year of age. It is associated with the emergence of allergen-specific IgE, but also with autoreactive IgE, whose function remain elusive. This review discusses current knowledge relevant to the mechanisms,...
Tue Sep 08, 2020 03:00
Antioxidants, Vol. 9, Pages 838: Vitamin D Protects against Oxidative Stress and Inflammation in Human Retinal Cells Antioxidants doi: 10.3390/antiox9090838 Authors: Patricia Fernandez-Robredo Jorge González-Zamora Sergio Recalde Valentina Bilbao-Malavé Jaione Bezunartea Maria Hernandez Alfredo Garcia-Layana Diabetic retinopathy is a vision-threatening microvascular complication of diabetes and is one of the leading causes of blindness. Oxidative stress and inflammation...
Tue Sep 08, 2020 03:00
Antioxidants, Vol. 9, Pages 840: Effects of Moringa oleifera Leaf Extract on Diabetes-Induced Alterations in Paraoxonase 1 and Catalase in Rats Analyzed through Progress Kinetic and Blind Docking Antioxidants doi: 10.3390/antiox9090840 Authors: Erick Sierra-Campos Mónica Valdez-Solana Claudia Avitia-Domínguez Mara Campos-Almazán Ismael Flores-Molina Guadalupe García-Arenas Alfredo Téllez-Valencia In our study, we aimed to evaluate the effects of Moringa oleifera leaves...
Tue Sep 08, 2020 03:00
Antioxidants, Vol. 9, Pages 841: Effect of High Hydrostatic Pressure Extraction on Biological Activities and Phenolics Composition of Winter Savory Leaf Extracts Antioxidants doi: 10.3390/antiox9090841 Authors: Sílvia A. Moreira Sara Silva Eduardo Costa Soraia Pinto Bruno Sarmento Jorge A. Saraiva Manuela Pintado Satureja montana L. has several biological properties related to its diverse composition of secondary metabolites. Nevertheless, it has been mainly studied...
Tue Sep 08, 2020 03:00
Antioxidants, Vol. 9, Pages 839: Pro-Aging Effects of Xanthine Oxidoreductase Products Antioxidants doi: 10.3390/antiox9090839 Authors: Maria Giulia Battelli Massimo Bortolotti Andrea Bolognesi Letizia Polito The senescence process is the result of a series of factors that start from the genetic constitution interacting with epigenetic modifications induced by endogenous and environmental causes and that lead to a progressive deterioration at the cellular and functional levels....
Tue Sep 08, 2020 03:00
Atmosphere, Vol. 11, Pages 958: C3 and C4 Grass Species: Who Can Reduce Soil Nitrous Oxide Emissions in a Continental Arid Region? Atmosphere doi: 10.3390/atmos11090958 Authors: Jiao Ning Xiong Z. He Fujiang Hou In order to relieve grazing pressure, drought-tolerant grass species are widely cultivated in arid regions. However, soil N emission is largely neglected while pursuing forage yield. We carried out a randomized block study to investigate whether and how the C3 and C4 grass...
Tue Sep 08, 2020 03:00
Biology, Vol. 9, Pages 279: Pituitary Actions of EGF on Gonadotropins, Growth Hormone, Prolactin and Somatolactins in Grass Carp Biology doi: 10.3390/biology9090279 Authors: Qiongyao Hu Qinbo Qin Shaohua Xu Lingling Zhou Chuanhui Xia Xuetao Shi Huiying Zhang Jingyi Jia Cheng Ye Zhan Yin Guangfu Hu In mammals, epidermal growth factor (EGF) plays a vital role in both pituitary physiology and pathology. However, the functional role of EGF in the regulation...
Tue Sep 08, 2020 03:00
Biomedicines, Vol. 8, Pages 335: Microbiota in Clostridioides difficile-Associated Diarrhea: Comparison in Recurrent and Non-Recurrent Infections Biomedicines doi: 10.3390/biomedicines8090335 Authors: Alessandra Gazzola Simona Panelli Marta Corbella Cristina Merla Francesco Comandatore Annalisa De Silvestri Antonio Piralla Valentina Zuccaro Claudio Bandi Piero Marone Patrizia Cambieri Clostridioides difficile infection (CDI) is the leading cause of antibiotic-associated...
Tue Sep 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1297: Cardioprotective Effects of Dietary Flaxseed Post-Infarction are Associated with Changes in MicroRNA Expression Biomolecules doi: 10.3390/biom10091297 Authors: Parikh Kura O’Hara Dibrov Netticadan Slezak Pierce MicroRNAs (miRNAs/miRs) such as miR-1, miR-133a, miR-133b, miR-135a, and miR-29b play a key role in many cardiac pathological remodeling processes, including apoptosis, fibrosis, and arrhythmias, after a myocardial infarction...
Tue Sep 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1296: Autophagy Inhibits Grass Carp Reovirus (GCRV) Replication and Protects Ctenopharyngodon idella Kidney (CIK) Cells from Excessive Inflammatory Responses after GCRV Infection Biomolecules doi: 10.3390/biom10091296 Authors: Pengfei Chu Libo He Rong Huang Lanjie Liao Yongming Li Zuoyan Zhu Wei Hu Yaping Wang Autophagy is an essential and highly conserved process in mammals, which is critical to maintaining physiological homeostasis,...
Tue Sep 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1294: The Pathophysiological Significance of Fibulin-3 Biomolecules doi: 10.3390/biom10091294 Authors: Imogen Livingstone Vladimir N. Uversky Dominic Furniss Akira Wiberg Fibulin-3 (also known as EGF-containing fibulin extracellular matrix protein 1 (EFEMP1)) is a secreted extracellular matrix glycoprotein, encoded by the EFEMP1 gene that belongs to the eight-membered fibulin protein family. It has emerged as a functionally unique member of this...
Tue Sep 08, 2020 03:00
Biomolecules, Vol. 10, Pages 1295: Targeting the Id1-Kif11 Axis in Triple-Negative Breast Cancer Using Combination Therapy Biomolecules doi: 10.3390/biom10091295 Authors: Archana P. Thankamony Reshma Murali Nitheesh Karthikeyan Binitha Anu Varghese Wee S. Teo Andrea McFarland Daniel L. Roden Holly Holliday Christina Valbirk Konrad Aurelie Cazet Eoin Dodson Jessica Yang Laura A. Baker Jason T. George Herbert Levine Mohit Kumar Jolly Alexander...
Tue Sep 08, 2020 03:00
Biosensors, Vol. 10, Pages 117: Transient Effect at the Onset of Human Running Biosensors doi: 10.3390/bios10090117 Authors: Christian Weich Manfred M. Vieten Randall L. Jensen While training and competing as a runner, athletes often sense an unsteady feeling during the first meters on the road. This sensation, termed as transient effect, disappears after a short period as the runners approach their individual running rhythm. The foundation of this work focuses on the detection...
Tue Sep 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 621: Reduced Interhemispheric Coherence after Cerebellar Vermis Output Perturbation Brain Sciences doi: 10.3390/brainsci10090621 Authors: Elena Laura Georgescu Margarint Ioana Antoaneta Georgescu Carmen-Denise-Mihaela Zahiu Alexandru Răzvan Șteopoaie Stefan-Alexandru Tirlea Daniela Popa Ana-Maria Zagrean Leon Zagrean Motor coordination and motor learning are well-known roles of the cerebellum. Recent evidence also supports the contribution...
Tue Sep 08, 2020 03:00
Brain Sciences, Vol. 10, Pages 622: Widespread Reductions of Spontaneous Neurophysiological Activity in Leber’s Disease—An Application of EEG Source Current Density Reconstruction Brain Sciences doi: 10.3390/brainsci10090622 Authors: Kamil Jonak Leber’s hereditary optic neuropathy (LHON) is a rare, maternally inherited genetic disease caused by a mutation of mitochondrial DNA. Classical descriptions have highlighted structural abnormalities in various parts of patients’...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2561: Pre- and Post-Surgical Dysphagia in Adults with Tumors of the Posterior Fossa: A Prospective Blinded Study Cancers doi: 10.3390/cancers12092561 Authors: Sriramya Lapa Johanna Quick-Weller Christiane Nasari Rainer Dziewas Florian Gessler Marlies Wagner Tobias Warnecke Elke Hattingen Volker Seifert Jürgen Konczalla Background: While swallowing disorders are frequent sequela following posterior fossa tumor (PFT) surgery in children,...
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Cancers, Vol. 12, Pages 2559: Insulin Resistance and Endometrial Cancer: Emerging Role for microRNA Cancers doi: 10.3390/cancers12092559 Authors: Iwona Sidorkiewicz Maciej Jóźwik Magdalena Niemira Adam Krętowski Endometrial cancer (EC) remains one of the most common cancers of the female reproductive system. Epidemiological and clinical data implicate insulin resistance (IR) and its accompanying hyperinsulinemia as key factors in the development of EC. MicroRNAs (miRNAs) are...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2555: Identification of Modulated MicroRNAs Associated with Breast Cancer, Diet, and Physical Activity Cancers doi: 10.3390/cancers12092555 Authors: Luca Falzone Maria Grimaldi Egidio Celentano Livia S. A. Augustin Massimo Libra Background: Several studies have shown that healthy lifestyles prevent the risk of breast cancer (BC) and are associated with better prognosis. It was hypothesized that lifestyle strategies induce microRNA (miRNA) modulation...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2560: The Effect of Resection Margin on Local Recurrence and Survival in High Grade Soft Tissue Sarcoma of the Extremities: How Far is Far Enough? Cancers doi: 10.3390/cancers12092560 Authors: Annika Bilgeri Alexander Klein Lars H. Lindner Silke Nachbichler Thomas Knösel Christof Birkenmaier Volkmar Jansson Andrea Baur-Melnyk Hans Roland Dürr Background: The significance of surgical margins after resection of soft tissue sarcomas in respect...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2556: Impact of Wnt/β-Catenin Inhibition on Cell Proliferation through CDC25A Downregulation in Soft Tissue Sarcomas Cancers doi: 10.3390/cancers12092556 Authors: Esther Martinez-Font Marina Pérez-Capó Rafael Ramos Irene Felipe Carmen Garcías Pablo Luna Josefa Terrasa Javier Martín-Broto Oliver Vögler Regina Alemany Antònia Obrador-Hevia The Wnt signaling pathway is an important cellular mechanism for regulating differentiation processes...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2558: Prolonging the Half-Life of Histone Deacetylase Inhibitor Belinostat via 50 nm Scale Liposomal Subcutaneous Delivery System for Peripheral T-Cell Lymphoma Cancers doi: 10.3390/cancers12092558 Authors: Meng-Hsuan Cheng Jun-Yi Weng Chih-Hung Chuang Wei-Ting Liao Yu-Fong Lai Jia-Yu Liu Yi-Ping Fang Lymph node metastasis is an aggressive condition characterized by poor treatment outcomes and low overall survival. Belinostat is a novel histone...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2554: Metformin Suppresses Cancer Stem Cells through AMPK Activation and Inhibition of Protein Prenylation of the Mevalonate Pathway in Colorectal Cancer Cancers doi: 10.3390/cancers12092554 Authors: Yoojeong Seo Janghyun Kim Soo Jung Park Jae Jun Park Jae Hee Cheon Won Ho Kim Tae Il Kim Metformin is a well-known AMPK (AMP-activated protein kinase) activator that suppresses cancer stem cells (CSCs) in some cancers. However, the mechanisms of...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2553: Fibronectin-Expressing Mesenchymal Tumor Cells Promote Breast Cancer Metastasis Cancers doi: 10.3390/cancers12092553 Authors: Brian H. Jun Tianqi Guo Sarah Libring Monica K. Chanda Juan Sebastian Paez Aparna Shinde Michael K. Wendt Pavlos P. Vlachos Luis Solorio Tumor metastasis is connected to epithelial-mesenchymal heterogeneity (EMH) and the extracellular matrix (ECM) within the tumor microenvironment. Mesenchymal-like fibronectin...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2551: Multi-Omics Investigation of Innate Navitoclax Resistance in Triple-Negative Breast Cancer Cells Cancers doi: 10.3390/cancers12092551 Authors: Michal Marczyk Gauri A. Patwardhan Jun Zhao Rihao Qu Xiaotong Li Vikram B. Wali Abhishek K. Gupta Manoj M. Pillai Yuval Kluger Qin Yan Christos Hatzis Lajos Pusztai Vignesh Gunasekharan Cancer cells employ various defense mechanisms against drug-induced cell death. Investigating...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2552: The Role of Non-Coding RNAs as Prognostic Factor, Predictor of Drug Response or Resistance and Pharmacological Targets, in the Cutaneous Squamous Cell Carcinoma Cancers doi: 10.3390/cancers12092552 Authors: Marianna Garofoli Mariateresa Volpicella Michele Guida Letizia Porcelli Amalia Azzariti Cutaneous squamous cell carcinoma (CSCC) is the most common keratinocyte-derived skin cancer in the Caucasian population. Exposure to UV radiations (UVRs)...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2557: Treatment of Metastatic Uveal Melanoma: Systematic Review Cancers doi: 10.3390/cancers12092557 Authors: Cristina Rodriguez-Vidal Daniel Fernandez-Diaz Beatriz Fernandez-Marta Nerea Lago-Baameiro María Pardo Paula Silva Laura Paniagua María José Blanco-Teijeiro Antonio Piñeiro Manuel Bande Introduction: More than 50% of patients with uveal melanoma end up developing metastases. Currently, there is no standard first-line treatment...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2550: Adherence Measures for Patients with Metastatic Castration-Resistant Prostate Cancer Treated with Abiraterone Acetate plus Prednisone: Results of a Prospective, Cluster-Randomized Trial Cancers doi: 10.3390/cancers12092550 Authors: Henrik Suttmann Jochen Gleissner Andreas Huebner Tim Mathes Werner Baurecht Katrin Krützfeldt Hussein Sweiti Susan Feyerabend Residual androgen production causes tumor progression in metastatic, castration-resistant...
Tue Sep 08, 2020 03:00
Cancers, Vol. 12, Pages 2549: Complex Renal Cysts (Bosniak ≥ IIF): Outcomes in a Population-Based Cohort Study Cancers doi: 10.3390/cancers12092549 Authors: James Lucocq Sanjay Pillai Richard Oparka Ghulam Nabi There is emerging evidence to suggest that con-current medical conditions influence the outcome of cancers, irrespective of therapy offered. The prevalence and impact of co-morbidities on the survival outcome of complex renal cystic masses in not known. The objective...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2054: Importance of Endocytosis for the Biological Activity of Cedar Virus Fusion Protein Cells doi: 10.3390/cells9092054 Authors: Kerstin Fischer Martin H. Groschup Sandra Diederich Endocytosis plays a particular role in the proteolytic activation of highly pathogenic henipaviruses Hendra (HeV) and Nipah virus (NiV) fusion (F) protein precursors. These proteins require endocytic uptake from the cell surface to be cleaved by cellular proteases within the endosomal...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2052: Association of the Hepatitis B Virus Large Surface Protein with Viral Infectivity and Endoplasmic Reticulum Stress-mediated Liver Carcinogenesis Cells doi: 10.3390/cells9092052 Authors: Wei-Ling Lin Jui-Hsiang Hung Wenya Huang Hepatitis B is the most prevalent viral hepatitis worldwide, affecting approximately one-third of the world’s population. Among HBV factors, the surface protein is the most sensitive biomarker for viral infection, given...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2055: Signalling, Metabolic Pathways and Iron Homeostasis in Endothelial Cells in Health, Atherosclerosis and Alzheimer’s Disease Cells doi: 10.3390/cells9092055 Authors: Emy Bosseboeuf Claudio Raimondi Endothelial cells drive the formation of new blood vessels in physiological and pathological contexts such as embryonic development, wound healing, cancer and ocular diseases. Once formed, all vessels of the vasculature system present an endothelial monolayer (the...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2053: Impact of Bone Marrow miR-21 Expression on Acute Myeloid Leukemia T Lymphocyte Fragility and Dysfunction Cells doi: 10.3390/cells9092053 Authors: Douâa Moussa Agha Redouane Rouas Mehdi Najar Fatima Bouhtit Hussein Fayyad-Kazan Laurence Lagneaux Dominique Bron Nathalie Meuleman Philippe Lewalle Makram Merimi Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy in which antitumor immunity is impaired. The therapeutic...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2048: HPLC-MS/MS Shows That the Cellular Uptake of All-Trans-Retinoic Acid under Hypoxia Is Downregulated by the Novel Active Agent 5-Methoxyleoligin Cells doi: 10.3390/cells9092048 Authors: Armin Sebastian Guntner Christian Doppler Christian Wechselberger David Bernhard Wolfgang Buchberger All-trans-retinoic acid (atRA) is the essential derivative of vitamin A and is of interest due to its various biological key functions. As shown in the recent literature,...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2050: Cytokines Explored in Saliva and Tears from Radiated Cancer Patients Correlate with Clinical Manifestations, Influencing Important Immunoregulatory Cellular Pathways Cells doi: 10.3390/cells9092050 Authors: Lara A. Aqrawi Xiangjun Chen Håvard Hynne Cecilie Amdal Sjur Reppe Hans Christian D. Aass Morten Rykke Lene Hystad Hove Alix Young Bente Brokstad Herlofson Kristine Løken Westgaard Tor Paaske Utheim Hilde Kanli Galtung Janicke...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2049: A Role for Caenorhabditis elegans COMPASS in Germline Chromatin Organization Cells doi: 10.3390/cells9092049 Authors: Marion Herbette Valérie Robert Aymeric Bailly Loïc Gely Robert Feil David Llères Francesca Palladino Deposition of histone H3 lysine 4 (H3K4) methylation at promoters is catalyzed by the SET1/COMPASS complex and is associated with context-dependent effects on gene expression and local changes in chromatin organization. The...
Tue Sep 08, 2020 03:00
Cells, Vol. 9, Pages 2047: Rebuilding Tendons: A Concise Review on the Potential of Dermal Fibroblasts Cells doi: 10.3390/cells9092047 Authors: Jin Chu Ming Lu Christian G. Pfeifer Volker Alt Denitsa Docheva Tendons are vital to joint movement by connecting muscles to bones. Along with an increasing incidence of tendon injuries, tendon disorders can burden the quality of life of patients or the career of athletes. Current treatments involve surgical reconstruction and conservative...
Tue Sep 08, 2020 03:00
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