Background Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive interstitial lung disease, characterized by a decline in lung function. To date, the pathophysiologic mechanisms associated with lung dysfunction remain unclear, and no effective therapy has been identified to improve lung function. Methods In the present study, we used weighted gene co-expression network analysis (WGCNA) to identify key modules...
Many natural wetlands have been converted to human-influenced wetlands. In some instances, human-influenced wetlands could provide complementary habitats for waterbirds, compensating for the loss of natural wetlands. Inner Deep Bay in Hong Kong is composed of both natural and human-influenced wetlands and is under immense development pressure. From an ecology perspective, we need to understand if different wetland types play the same ecological role. To achieve this, we tracked nine little egrets...
Drought is a natural hazard, which is a result of a prolonged shortage of precipitation, high temperature and change in the weather pattern. Drought harms society, the economy and the natural environment, but it is difficult to identify and characterize. Many areas of Pakistan have suffered severe droughts during the last three decades due to changes in the weather pattern. A drought analysis with the incorporation of climate information has not yet been undertaken in this study region. Here, we...
Mechanisms of diversity maintenance in dung beetle assemblages in a heterogeneous tropical landscape
Background Anthropized landscapes play a crucial role in biodiversity conservation, as they encompass about 90% of the remaining tropical forest. Effective conservation strategies require a deep understanding of how anthropic disturbances determine diversity patterns across these landscapes. Here, we evaluated how attributes and assembly mechanisms of dung beetle communities vary across the Selva El Ocote Biosphere Reserve (REBISO) landscape. ...
Background Minimal change disease (MCD) is a common form of nephrotic syndrome in adults. However, the molecular mechanism underlying the pathogenesis of MCD remains incompletely understood. In this study, we aimed to investigate the role of the cytokines expression of Th1/Th2/Th17 and urinary CD80 excretion in adult-onset MCD patients. Methods The lymphocyte subsets, 34 cytokine levels of Th1/Th2/Th17, serum and urine...
Background Birds show adaptations in limb bone shape that are associated with resisting locomotor loads. Whether comparable adaptations occur in the microstructure of avian cortical bone is less clear. One proposed microstructural adaptation is laminar bone in which the proportion of circumferentially-oriented vascular canals (i.e., laminarity) is large. Previous work on adult birds shows elevated laminarity in specific limb elements of some taxa, presumably to resist torsion-induced shear strain...
Collaborative hunting by complex social groups is a hallmark of large dogs (Mammalia: Carnivora: Canidae), whose teeth also tend to be hypercarnivorous, specialized toward increased cutting edges for meat consumption and robust p4-m1 complex for cracking bone. The deep history of canid pack hunting is, however, obscure because behavioral evidence is rarely preserved in fossils. Dated to the Early Pleistocene (>1.2 Ma), Canis chihliensis from the Nihewan Basin of northern China is one of the earliest...
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Wuhan City, China, late in December 2019 is an example of an emerging zoonotic virus that threatens public health and international travel and commerce. When such a virus emerges, there is often insufficient specific information available on mechanisms of virus dissemination from animal-to-human or from person-to-person, on the level or route of infection transmissibility or of viral release in body secretions/excretions,...
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Researchers at Purdue University have developed a wearable device that can administer antibacterial ozone gas to chronic wounds to help disinfect them. The technology could allow people to disinfect chronic wounds at home, and would be helpful in cases where wounds have been colonized by drug-resistant bacteria and aren’t responding to antibiotic therapy. Approximately 6 million patients in the U.S. have a chronic wound. This includes many patients with diabetes who develop foot ulcers....
Researchers at George Washington University and Northwestern University have developed a new class of soft devices that can provide new functionality for catheters used in cardiac procedures. The new materials are soft electronics, including stretchable sensors and actuators, that when applied to the surface of a catheter system, could greatly assist in diagnosing and treating cardiac conditions. Catheter-based therapy for conditions such as cardiac arrhythmias is well-established....
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Abstract Background In accordance with the principle of training specificity, adaptations to vertically or horizontally orientated plyometric training (VPT, HPT) directly transfer to athletic tasks that are carried out in the same direction as they are performed. Objectives The objective of this systematic review and meta-analysis was to determine...
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Related Articles [Attention should be paid to the neuromodulation therapy of autonomic nervous dysfunction]. Zhonghua Yi Xue Za Zhi. 2020 Sep 08;100(33):2561-2564 Authors: Ni HD, Huang B, Yao M, Zhu JJ, Tao JC PMID: 32892602 [PubMed - in process]
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Publication date: October 2020Source: Clinical Neurophysiology, Volume 131, Issue 10Author(s): Yoshinobu Goto, Shozo Tobimatsu, Takao Yamasaki, Ichiro Sasaki, Tatsuya Sasaki, Akihiro Yasuhara
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Publication date: October 2020Source: Clinical Neurophysiology, Volume 131, Issue 10Author(s): Matoba Kento, Shimotake Akihiro, Imamura Hisashi, Yamao Yukihiro, Usami Kiyohide, Kikuchi Takayuki, Yoshida Kazumichi, Matsuhashi Masao, Kunieda Takeharu, Miyamoto Susumu, Takahashi Ryosuke, Matsumoto Riki, Ikeda Akio
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O1-078 Modality-specific changes in somatosensory evoked potentials and Go/no-go discrimination time
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