Related Articles Predictive value of quantitative 18F-FDG-PET radiomics analysis in patients with head and neck squamous cell carcinoma. EJNMMI Res. 2020 Sep 07;10(1):102 Authors: Martens RM, Koopman T, Noij DP, Pfaehler E, Übelhör C, Sharma S, Vergeer MR, Leemans CR, Hoekstra OS, Yaqub M, Zwezerijnen GJ, Heymans MW, Peeters CFW, de Bree R, de Graaf P, Castelijns JA, Boellaard R Abstract BACKGROUND: Radiomics is aimed at image-based tumor...
Tue Sep 08, 2020 14:40
Related Articles Cough reflex testing in acute stroke: A survey of current UK service provision and speech and language therapist perceptions. Int J Lang Commun Disord. 2020 Sep 07;: Authors: Trimble J, Patterson J Abstract BACKGROUND: Silent aspiration (SA)-airway entry of food, drink or other material without a cough response-is common post-stroke. Clinical swallowing examination misses up to 40% of dysphagic patients with SA. This may...
Tue Sep 08, 2020 14:40
Related Articles Defining a Distinct Immunotherapy Eligible Subset of Patients with Cancer of Unknown Primary Using Gene Expression Profiling with the 92-Gene Assay. Oncologist. 2020 Sep 07;: Authors: Raghav K, Overman M, Poage GM, Soifer HS, Schnabel CA, Varadhachary GR Abstract BACKGROUND: Although recent advances in immunotherapy have transformed the treatment landscape for many anatomically defined cancers, these therapies are currently...
Tue Sep 08, 2020 14:40
Related Articles Biomarkers for diagnosis and prediction of therapy responses in allergic diseases and asthma. Allergy. 2020 Sep 07;: Authors: Breiteneder H, Peng YQ, Agache I, Diamant Z, Eiwegger T, Fokkens WJ, Traidl-Hoffmann C, Nadeau K, O'Hehir RE, O'Mahony L, Pfaar O, Torres MJ, Wang DY, Zhang L, Akdis CA Abstract Modern healthcare requires a proactive and individualized response to diseases, combining precision diagnosis and personalized...
Tue Sep 08, 2020 14:40
Related Articles Orthodontic treatment need and timing: Assessment of evolutive malocclusion conditions and associated risk factors. Eur J Paediatr Dent. 2020 Sep;21(3):203-208 Authors: Grippaudo MM, Quinzi V, Manai A, Paolantonio EG, Valente F, La Torre G, Marzo G Abstract AIM: Orthodontic treatment need indexes are indispensable tools for collecting aepidemiological information, to define the need for clinical intervention on a graduated...
Tue Sep 08, 2020 14:40
Related Articles Management of the positive sentinel lymph node in the post-MSLT-II era. J Surg Oncol. 2020 Sep 06;: Authors: Bredbeck BC, Mubarak E, Zubieta DG, Tesorero R, Holmes AR, Dossett LA, VanKoevering KK, Durham AB, Hughes TM Abstract BACKGROUND AND OBJECTIVES: The publication of MSLT-II shifted recommendations for management of sentinel lymph node biopsy positive (SLNB+) melanoma to favor active surveillance. We examined trends...
Tue Sep 08, 2020 14:40
Related Articles Transoral laser microsurgery and radiotherapy for oropharyngeal squamous cell carcinoma: Equitable survival and enhanced function compared with contemporary standards of care. Eur J Surg Oncol. 2020 Jul 22;: Authors: Dalton CL, Milinis K, Houghton D, Ridley P, Davies K, Williams R, Hamilton D, Wilkie MD, Markey A, Clarke K, Lofthouse M, Helliwell TR, Triantafyllou A, Rodrigues J, Bheemireddy K, Hanlon R, Wieshmann H, Haridass A, Brammer C,...
Tue Sep 08, 2020 14:40
Related Articles Oral Biopsy Techniques. Dermatol Clin. 2020 Oct;38(4):421-427 Authors: Shanti RM, Tanaka T, Stanton DC Abstract Squamous cell carcinoma makes up 90% of cases of oral cancer. However, a myriad of premalignant, inflammatory, and immune-based conditions can manifest as oral mucosal lesions. Biopsy of these lesions shares many of the principles of cutaneous lesions. Biopsy of oral mucosal lesions is a procedure that is safely...
Tue Sep 08, 2020 14:40
Related Articles Recent Advances in Microsurgery: An Update in the Past 4 Years. Clin Plast Surg. 2020 Oct;47(4):663-677 Authors: Mohan AT, Saint-Cyr M Abstract Microsurgery has broad applications in reconstructive surgery. As techniques, diagnostics, and advancing technology rapidly evolve, reconstructive microsurgeons can adapt to address new challenges and push the frontiers to achieve optimal functional and aesthetic reconstruction,...
Tue Sep 08, 2020 14:40
Related Articles Innovations and Future Directions in Head and Neck Microsurgical Reconstruction. Clin Plast Surg. 2020 Oct;47(4):573-593 Authors: Suchyta M, Mardini S Abstract Head and neck reconstructive microsurgery is constantly innovating because of a combination of multidisciplinary advances. This article examines recent innovations that have affected the field as well as presenting research leading to future advancement. Innovations...
Tue Sep 08, 2020 14:40
Related Articles The association between frailty and severe disease among COVID-19 patients aged over 60 years in China: a prospective cohort study. BMC Med. 2020 Sep 07;18(1):274 Authors: Ma Y, Hou L, Yang X, Huang Z, Yang X, Zhao N, He M, Shi Y, Kang Y, Yue J, Wu C Abstract BACKGROUND: The coronavirus disease 2019 (COVID-19) has been a pandemic worldwide. Old age and underlying illnesses are associated with poor prognosis among COVID-19...
Tue Sep 08, 2020 14:40
Related Articles [Finite element analysis of evaluating the change of the hip joint biomechanics following femoral neck shortening after cannulated screw fixation for osteoporotic femoral neck fracture]. Zhonghua Yi Xue Za Zhi. 2020 Sep 08;100(33):2628-2632 Authors: Yu X, Zhang DF, Song MS, Chen ZM, Yang K, Pang QJ Abstract Objective: To evaluate the stress status of femoral head and neck, screws and acetabulum caused by femoral neck shortening...
Tue Sep 08, 2020 14:40
Related Articles [Advances in clinicopathology and molecular genetics of adenoid cystic carcinoma of the head and neck]. Zhonghua Bing Li Xue Za Zhi. 2020 Sep 08;49(9):968-972 Authors: Xuan LL, Liu HG PMID: 32892573 [PubMed - in process]
Tue Sep 08, 2020 14:40
Related Articles Mass-surveillance technologies to fight coronavirus spread: the case of Israel. Nat Med. 2020 08;26(8):1167-1169 Authors: Amit M, Kimhi H, Bader T, Chen J, Glassberg E, Benov A PMID: 32457444 [PubMed - indexed for MEDLINE]
Tue Sep 08, 2020 14:40
Related Articles An Unusual Bump on the Head: Intracranial and Extracranial Cytokeratin-Positive Interstitial Reticular Cell Tumor. World Neurosurg. 2020 07;139:60-62 Authors: Eberhard N, Cordier D Abstract BACKGROUND: We describe a cytokeratin positive interstitial reticulum cell tumor (CPIRCT) as the cause of a large and defacing scalp tumor. Clinically these tumors manifest as progressive, painless swelling. Treatment usually consists of...
Tue Sep 08, 2020 14:40
Related Articles Association between Sudden Sensorineural Hearing Loss and Preexisting Thyroid Diseases: A Nationwide Case-Control Study in Taiwan. Int J Environ Res Public Health. 2020 01 29;17(3): Authors: Tsai YT, Chang IJ, Hsu CM, Yang YH, Liu CY, Tsai MS, Chang GH, Lee YC, Huang EI, Lin MH, Luan CW Abstract Background: Little evidence is available about the risk of sudden sensorineural hearing loss (SSNHL) in patients with thyroid diseases....
Tue Sep 08, 2020 14:40
Related Articles Safety of nasal stenting in pharyngeal flap surgery for pediatric velopharyngeal dysfunction. Int J Pediatr Otorhinolaryngol. 2020 Mar;130:109804 Authors: Araslanova R, Instrum R, Dzioba A, Husein M Abstract INTRODUCTION: The pharyngeal flap procedure is an effective surgery for velopharyngeal dysfunction (VPD) yet carries approximately a 3.2% post-operative airway obstruction risk. Life threatening airway compromise occurs...
Tue Sep 08, 2020 14:40
Related Articles Pediatric adenoidectomy in the very young child and indications for postoperative inpatient admission. Int J Pediatr Otorhinolaryngol. 2020 Mar;130:109796 Authors: Chorney SR, Dailey JF, Zur KB Abstract OBJECTIVES: To determine the rate of significant respiratory events following adenoidectomy in young patients and to identify factors that would prompt inpatient admission postoperatively. METHODS: A retrospective chart...
Tue Sep 08, 2020 14:40
Related Articles Lung Lavage Granulocyte Patterns and Clinical Phenotypes in Children with Severe, Therapy-Resistant Asthma. J Allergy Clin Immunol Pract. 2019 Jul - Aug;7(6):1803-1812.e10 Authors: Teague WG, Lawrence MG, Shirley DT, Garrod AS, Early SV, Payne JB, Wisniewski JA, Heymann PW, Daniero JJ, Steinke JW, Froh DK, Braciale TJ, Ellwood M, Harris D, Borish L Abstract BACKGROUND: Children with severe asthma have frequent exacerbations...
Tue Sep 08, 2020 14:40
Related Articles Evaluation of Accuracy for 18 F-FDG Positron Emission Tomography and Computed Tomography for Detection of Lymph Node Metastasis in Canine Oral Malignant Melanoma. Vet Comp Oncol. 2020 Sep 06;: Authors: Willcox JL, Spriet M, Zwingenberger AL, Phillips KL, Burton JH, Skorupski KA, Hansen KS, Affolter VK, Woolard KD, Beylin D, Giuffrida MA Abstract Tumor stage has been demonstrated to have prognostic significance in canine...
Tue Sep 08, 2020 11:06
Related Articles Transcriptomic Analysis of Peripheral Blood Mononuclear Cells in HNSCC Patients. Oral Dis. 2020 Sep 06;: Authors: Bin-Alee F, Arayataweegool A, Buranapraditkun S, Mahattanasakul P, Tangjaturonrasme N, Hirankarn N, Mutirangura A, Kitkumthorn N Abstract OBJECTIVES: To investigate the gene expression profile of peripheral blood mononuclear cells (PBMCs) from head and neck squamous cell carcinoma (HNSCC), including oral cancer...
Tue Sep 08, 2020 11:06
Related Articles Investigation on chronic tinnitus efficacy of combination of non-repetitive preferred music and educational counseling: a preliminary study. Eur Arch Otorhinolaryngol. 2020 Sep 05;: Authors: Chen J, Zhong P, Meng Z, Pan F, Qi L, He T, Lu J, He P, Zheng Y Abstract PURPOSE: To improve the efficacy of music therapy on tinnitus relief, specific music that was not repetitively played and satisfies individualized preference was...
Tue Sep 08, 2020 11:06
Related Articles CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features. Mod Pathol. 2020 Sep 05;: Authors: Williams EA, Montesion M, Alexander BM, Ramkissoon SH, Elvin JA, Ross JS, Williams KJ, Glomski K, Bledsoe JR, Tse JY, Mochel MC Abstract Mutations in the tumor suppressor CYLD, known to be causative of cylindromas, were...
Tue Sep 08, 2020 11:06
Related Articles A Nested Mixed Effects Multicenter Model Examining the Risk Factors for Pediatric Trauma Return Visits Within 72 h. J Surg Res. 2020 Sep 03;257:370-378 Authors: Ehwerhemuepha L, Yu PT, Guner YS, Wallace E, Feaster W Abstract BACKGROUND: Return visits within 72 h are an important metric in evaluating the performance of emergency rooms. This has not been well studied in the pediatric trauma population. We sought to determine...
Tue Sep 08, 2020 11:06
Related Articles Intraoperative ketorolac for pediatric tonsillectomy: Effect on post-tonsillectomy hemorrhage and perioperative analgesia. Int J Pediatr Otorhinolaryngol. 2020 Aug 28;138:110341 Authors: Rabbani CC, Pflum ZE, Ye MJ, Gettelfinger JD, Sadhasivam S, Matt BH, Dahl JP Abstract OBJECTIVE: Determine the impact of ketorolac on post-tonsillectomy hemorrhage (PTH) and narcotic administration in children undergoing tonsillectomy....
Tue Sep 08, 2020 11:06
Related Articles Interstate variation within a five-state health system: Polysomnography prior to tonsillectomy in trisomy 21 patients. Int J Pediatr Otorhinolaryngol. 2020 Aug 29;138:110336 Authors: Kolb CM, Shah U, Aaronson NL Abstract OBJECTIVES: Since 2011, the American Academy of Otolaryngology - Head and Neck Surgery Clinical Practice Guidelines have recommended polysomnography (PSG) prior to tonsillectomy in children with Down syndrome...
Tue Sep 08, 2020 11:06
Related Articles Supraglottoplasty for severe laryngomalacia. Can we predict success? Int J Pediatr Otorhinolaryngol. 2020 Aug 28;138:110333 Authors: Cohen O, Picard E, Joseph L, Schwartz Y, Sichel JY, Attal P Abstract OBJECTIVES: Laryngomalacia is the dynamic collapse of supraglottic structures during inspiration, leading to a variable degree of airway obstruction. Clinical symptoms appear in the first months of life and are usually mild...
Tue Sep 08, 2020 11:06
Related Articles Endoscopic anterior-posterior cricoid split to avoid tracheostomy in infants with bilateral vocal fold paralysis. Int J Pediatr Otorhinolaryngol. 2020 Aug 20;138:110325 Authors: Windsor AM, Jacobs I Abstract INTRODUCTION: Infants with bilateral vocal fold paralysis (BVFP) can present with stridor and respiratory distress necessitating tracheostomy. The endoscopic anterior-posterior cricoid split (APCS) with balloon dilation...
Tue Sep 08, 2020 11:06
Related Articles International Pediatric Otolaryngology Group (IPOG): Consensus recommendations on the prenatal and perinatal management of anticipated airway obstruction. Int J Pediatr Otorhinolaryngol. 2020 Aug 08;138:110281 Authors: Puricelli MD, Rahbar R, Allen GC, Balakrishnan K, Brigger MT, Daniel SJ, Fayoux P, Goudy S, Hewitt R, Hsu WC, Ida JB, Johnson R, Leboulanger N, Rickert SM, Roy S, Russell J, Rutter M, Sidell D, Soma M, Thierry B, Trozzi M, Zalzal...
Tue Sep 08, 2020 11:06
Related Articles Evaluation of a 3D-Printed-Head Simulation Technique for Teaching Flexible Nasopharyngoscopy to Radiation Oncology Residents. Int J Radiat Oncol Biol Phys. 2020 Sep 03;: Authors: Goodman CD, Pautler JD, Balestrini CS, Cobos S, D'Souza L, Eansor P, Jaswal J, Nichols A, Norris M, Sharma M, Willmore K, Warner A, Murrell DH, Palma DA Abstract PURPOSE: Simulation-based medical education (SBME) is an effective tool for medical...
Tue Sep 08, 2020 11:06
Related Articles Toxicogenomic study to identify potential signaling alterations related to nasal inflammatory damages induced by diesel exhaust particles in primary human nasal epithelial cells. Toxicol In Vitro. 2020 Sep 03;:104994 Authors: Kim HS, Kim HJ, Kim N, Song JJ, Son BS, Yang JH, Lee CM, Park MK, Seo YR Abstract In this study, we aimed to identify signaling alteration caused by exposure to diesel exhaust particles (DEPs) \using...
Tue Sep 08, 2020 11:06
Related Articles Radiosensitisation and enhanced tumour growth delay of colorectal cancer cells by sustained treatment with trifluridine/tipiracil and X-rays. Cancer Lett. 2020 Sep 03;: Authors: Rothkamm K, Christiansen S, Rieckmann T, Horn M, Frenzel T, Brinker A, Schumacher U, Stein A, Petersen C, Burdak-Rothkamm S Abstract Trifluridine/tipiracil (FTD/TPI; marketed as Lonsurf®) has shown clinically relevant activity after fluoropyrimidine...
Tue Sep 08, 2020 11:06
Related Articles Impact of SCID mouse gender on tumorigenicity, xenograft growth and drug-response in a large panel of orthotopic PDX models of pediatric brain tumors. Cancer Lett. 2020 Sep 03;: Authors: Qi L, Kogiso M, Du Y, Zhang H, Braun FK, Huang Y, Teo WY, Lindsay H, Zhao S, Baxter P, Zhao X, Yu L, Liu Z, Zhang X, Su JM, Adesina A, Yang J, Chintagumpala M, Perlaky L, Tsz-Kwong Man C, Lau CC, Li XN Abstract Brain tumor is the leading...
Tue Sep 08, 2020 11:06
Related Articles Eagle's syndrome, elongated styloid process and new evidence for pre-manipulative precautions for potential cervical arterial dysfunction. Musculoskelet Sci Pract. 2020 Jul 25;:102219 Authors: Westbrook AM, Kabbaz VJ, Showalter CR Abstract INTRODUCTION: Safety with upper cervical interventions is a frequently discussed and updated concern for physical therapists, chiropractors and osteopaths. IFOMPT developed the framework...
Tue Sep 08, 2020 11:06
Related Articles Short-term surgical missions to resource-limited settings in the wake of the COVID-19 pandemic. J Plast Reconstr Aesthet Surg. 2020 Aug 29;: Authors: Honeyman C, Patel V, Almas F, Bradley D, Martin D, McGurk M PMID: 32891553 [PubMed - as supplied by publisher]
Tue Sep 08, 2020 11:06
Related Articles Handle-On-QOL: a dedicated quality of life resource following the diagnosis and treatment of head and neck cancer. Br J Oral Maxillofac Surg. 2020 Sep 02;: Authors: Walshaw EG, Smith M, Kanatas A, Rogers SN Abstract Measuring quality of life (QOL) after head and neck cancer (HNC), is rapidly becoming the standard of care. The Head and Neck Database Listing Evidence on QOL (Handle-On-QOL) is a dedicated QOL resource that...
Tue Sep 08, 2020 11:06
Related Articles CAD-CAM vs conventional technique for mandibular reconstruction with free fibula flap: A comparison of outcomes. Surg Oncol. 2020 Sep;34:284-291 Authors: Mahendru S, Jain R, Aggarwal A, Aulakh HS, Jain A, Khazanchi RK, Sarin D Abstract INTRODUCTION: Mandibular reconstruction always pose a challenge to the reconstructive surgeon. With the use of Computer aided designing and computer aided manufacturing (CAD-CAM) it is now...
Tue Sep 08, 2020 11:06
Related Articles Enhanced recovery after surgery program involving preoperative dexamethasone administration for head and neck surgery with free tissue transfer reconstruction: Single-center prospective observational study. Surg Oncol. 2020 Sep;34:197-205 Authors: Imai T, Kurosawa K, Asada Y, Momma Y, Takahashi M, Satake N, Azuma M, Suzuki A, Sasaki M, Morita S, Saijo S, Fujii K, Kishimoto K, Yamazaki T, Goto T, Matsuura K Abstract BACKGROUND:...
Tue Sep 08, 2020 11:06
Related Articles How to select candidates for microvascular head and neck reconstruction in the elderly? Predictive factors of postoperative outcomes. Surg Oncol. 2020 Sep;34:168-173 Authors: D'Andréa G, Scheller B, Gal J, Chamorey E, Château Y, Dassonville O, Poissonnet G, Culié D, Koulmann PH, Hechema R, Demard F, Elaldi R, Bozec A Abstract INTRODUCTION: The proportion of elderly patients with head and neck cancer is increasing. However,...
Tue Sep 08, 2020 11:06
Related Articles Immunohistochemical basigin expression level in thyroid cancer tissues. World J Surg Oncol. 2020 Sep 05;18(1):240 Authors: Guo WP, Tang D, Pang YY, Li XJ, Chen G, Huang ZG, Tang XZ, Lai QQ, Gan JY, Huang XL, Liu XF, Wei ZX, Ma W Abstract BACKGROUND: Thyroid cancer (TC) is the most common endocrine malignancy; basigin (also known as BSG) plays a crucial role in tumor cell invasion, metastasis, and angiogenesis. This study...
Tue Sep 08, 2020 11:06
Related Articles Do reminder emails and past due notifications improve patient completion and institutional data submission for patient-reported outcome measures? Qual Life Res. 2020 Sep 07;: Authors: Pugh SL, Rodgers JP, Moughan J, Bonanni R, Boparai J, Chen RC, Dignam JJ, Bruner DW Abstract PURPOSE: NRG Oncology, part of the National Cancer Institute's National Clinical Trials Network, took efforts to increase patient-reported outcome measures...
Tue Sep 08, 2020 14:38
Related Articles Gastric cancer: a comprehensive review of current and future treatment strategies. Cancer Metastasis Rev. 2020 Sep 07;: Authors: Sexton RE, Al Hallak MN, Diab M, Azmi AS Abstract Gastric cancer remains a major unmet clinical problem with over 1 million new cases worldwide. It is the fourth most commonly occurring cancer in men and the seventh most commonly occurring cancer in women. A major fraction of gastric cancer has been...
Tue Sep 08, 2020 14:38
Related Articles Issues to be considered to address the future liver remnant prior to major hepatectomy. Surg Today. 2020 Sep 07;: Authors: Kishi Y, Vauthey JN Abstract An accurate preoperative evaluation of the hepatic function and application of portal vein embolization in selected patients have helped improve the safety of major hepatectomy. In planning major hepatectomy, however, several issues remain to be addressed. The first is which...
Tue Sep 08, 2020 14:38
Related Articles Histological diagnosis of immune checkpoint inhibitor induced acute renal injury in patients with metastatic melanoma: a retrospective case series report. BMC Nephrol. 2020 Sep 07;21(1):391 Authors: Hultin S, Nahar K, Menzies AM, Long GV, Fernando SL, Atkinson V, Cebon J, Wong MG Abstract BACKGROUND: Immune checkpoint inhibitors (ICI) have become the standard of care in many oncological conditions but are associated with a spectrum...
Tue Sep 08, 2020 14:38
Related Articles Genome-wide CRISPR screens for the identification of therapeutic targets for cancer treatment. Expert Opin Ther Targets. 2020 Sep 05;: Authors: Xue VW, Wong SCC, Cho WCS Abstract INTRODUCTION: Exploring the function of every gene is a challenging task. There is a paradigm shift of RNA interference with the introduction of clustered regularly interspaced short palindromic repeat (CRISPR)-based genome-wide screening. CRISPR-based...
Tue Sep 08, 2020 14:38
Related Articles Tailoring Virtual Human-Delivered Interventions: A Digital Intervention promoting Colorectal Cancer Screening for Black Women. Psychooncology. 2020 Sep 06;: Authors: Vilaro MJ, Wilson-Howard DS, Griffin LN, Tavassoli F, Zalake MS, Lok BC, Modave FP, George TJ, Carek PJ, Krieger JL Abstract OBJECTIVE: Despite efforts to reduce cancer disparities, Black women remain underrepresented in cancer research. Virtual health assistants...
Tue Sep 08, 2020 14:38
Related Articles Application of the ESMO-Magnitude of Clinical Benefit Scale (V.1.1) to the field of early breast cancer therapies. ESMO Open. 2020 Sep;5(5): Authors: Paluch-Shimon S, Cherny NI, de Vries EGE, Dafni U, Piccart MJ, Latino NJ, Cardoso F Abstract Click here to listen to the Podcast BACKGROUND: The European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) is a validated value scale for solid tumour anticancer...
Tue Sep 08, 2020 14:38
Related Articles Lessons learnt from scoring adjuvant colon cancer trials and meta-analyses using the ESMO-Magnitude of Clinical Benefit Scale V.1.1. ESMO Open. 2020 Sep;5(5): Authors: Knapen DG, Cherny NI, Zygoura P, Latino NJ, Douillard JY, Dafni U, de Vries EGE, de Groot DJ Abstract Click here to listen to the Podcast BACKGROUND: Form 1 of the European Society for Medical Oncology-Magnitude of Clinical Benefit Scale (ESMO-MCBS) serves to...
Tue Sep 08, 2020 14:38
Related Articles The Impact of the COVID-19 Pandemic on Genitourinary Cancer Care: Re-envisioning the Future. Eur Urol. 2020 Sep 03;: Authors: Wallis CJD, Catto JWF, Finelli A, Glaser AW, Gore JL, Loeb S, Morgan TM, Morgans AK, Mottet N, Neal R, O'Brien T, Odisho AY, Powles T, Skolarus TA, Smith AB, Szabados B, Klaassen Z, Spratt DE Abstract CONTEXT: The coronavirus disease 2019 (COVID-19) pandemic necessitated rapid changes in medical practice....
Tue Sep 08, 2020 14:38
Related Articles Pattern of tumor invasion, stromal inflammation, angiogenesis and vascular invasion in oral squamous cell carcinoma - A prognostic study. Curr Probl Cancer. 2020 Sep 02;:100647 Authors: Sethi S, Grewal H, Aggarwal P, Narad C Abstract INTRODUCTION: Oral cancer is one of the leading causes of mortality, and its worsening impact on the society has revealed the danger it poses in the coming future. Several researchers proposed and...
Tue Sep 08, 2020 14:38
Related Articles Survival nomogram for patients with upper tract recurrence after resection for localized bladder urothelial carcinoma. Future Oncol. 2020 Sep 05;: Authors: Hou G, Zheng W, Zhang W, Zheng Y, Zhang L, Gao M, Yan F, Wei D, Wang F, Yuan J Abstract Aim: To develop a survival nomogram for patients with upper tract recurrence (UTR) after resection for localized bladder urothelial carcinoma (BUC). Methods: The data of 361 patients with...
Tue Sep 08, 2020 14:38
Related Articles The role of marital status on the prognosis in esophagus adenocarcinoma: a real-world competing risk analysis. Future Oncol. 2020 Sep 05;: Authors: Lan T, Liu W, Lu Y, Zheng R, Luo H, Shao X, He J Abstract Aim: The purpose of this study was to assess the role of marital status in esophageal adenocarcinoma (EAC). Methods: We identified 8341 EAC patients based on the Surveillance, Epidemiology and End Results database during 2007-2015,...
Tue Sep 08, 2020 14:38
Related Articles Artificial intelligence technology applications in the pathologic diagnosis of the gastrointestinal tract. Future Oncol. 2020 Sep 05;: Authors: Lino-Silva LS, Xinaxtle DL Abstract Artificial intelligence (AI) is a complex technology with a steady flow of new applications, including in the pathology laboratory. Applications of AI in pathology are scarce but increasing; they are based on complex software-based machine learning...
Tue Sep 08, 2020 14:38
Related Articles Reorganization of Istituti Fisioterapici Ospitalieri, an oncological and dermatological clinical and research center, to face the coronavirus health emergency: adopted measures and metrics of success to achieve and keep a COVID-19-free status. J Exp Clin Cancer Res. 2020 Sep 01;39(1):177 Authors: De Luca A, Ripa di Meana F, Vujovic B, Morrone A, Degirolamo C, Ciliberto G, Lavalle T Abstract BACKGROUND: A pronounced polarization...
Tue Sep 08, 2020 14:38
Related Articles The immunohistochemical, DNA methylation, and chromosomal copy number profile of cauda equina paraganglioma is distinct from extra-spinal paraganglioma. Acta Neuropathol. 2020 Sep 06;: Authors: Ramani B, Gupta R, Wu J, Barreto J, Bollen AW, Tihan T, Mummaneni PV, Ames C, Clark A, Oberheim Bush NA, Butowski N, Phillips D, King BE, Bator SM, Treynor EC, Zherebitskiy V, Quinn PS, Walker JB, Pekmezci M, Sullivan DV, Hofmann JW, Sloan EA, M Chang...
Tue Sep 08, 2020 11:09
Related Articles In vitro screening of plant extracts traditionally used as cancer remedies in Ghana - 15-Hydroxyangustilobine A as the active principle in Alstonia boonei leaves. J Ethnopharmacol. 2020 Sep 03;:113359 Authors: Spiegler V, Greiffer L, Jacobtorweihen J, Asase A, Lanvers-Kaminsky C, Hempel G, Agyare C, Hensel A Abstract ETHNOPHARMACOLOGICAL RELEVANCE: Cancer represents a major health burden and drain on the global healthcare systems....
Tue Sep 08, 2020 11:09
Related Articles Improving the function of neutrophils from chronic granulomatous disease patients using mesenchymal stem cells' exosomes. Hum Immunol. 2020 Sep 02;: Authors: Taghavi-Farahabadi M, Mahmoudi M, Mahdaviani SA, Baghaei K, Rayzan E, Hashemi SM, Rezaei N Abstract In chronic granulomatous disease (CGD) patients, reactive oxygen species (ROS) production by neutrophils is impaired. So, they are susceptible to infections. Studies showed...
Tue Sep 08, 2020 11:09
New England Journal of Medicine, Ahead of Print.
Mon Sep 07, 2020 11:40
New England Journal of Medicine, Ahead of Print.
Mon Sep 07, 2020 06:24
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Fotis G. Souslian, Puja D. Patel, Mohamed A. Elsherif
Tue Sep 08, 2020 14:31
Publication date: November 2020Source: World Neurosurgery, Volume 143Author(s): Mohamed S. Muneer, Charles A. Ritchie, Nathan Todnem, Neethu Gopal, Ricardo Paz-Fumagalli, Beau B. Toskich, Rabih G. Tawk
Tue Sep 08, 2020 14:31
Related Articles MiR-34a affects G2 arrest in prostate cancer PC3 cells via Wnt pathway and inhibits cell growth and migration. Eur Rev Med Pharmacol Sci. 2020 Aug;24(16):8349-8358 Authors: Dong B, Xu GC, Liu ST, Liu T, Geng B Abstract OBJECTIVE: To investigate the effect and mechanism of miRNA-34a overexpression on proliferation and migration of PC3 prostate cancer cells. PATIENTS AND METHODS: Benign prostatic hyperplasia tissue...
Tue Sep 08, 2020 14:29
Related Articles Topological Features of Histone H2A Monoubiquitination. Dokl Biochem Biophys. 2020 Jul;493(1):193-197 Authors: Kudriaeva AA, Lipkin VM, Belogurov AA Abstract The cellular response to DNA damage protects the essential information stored in the genome. This mechanism is crucial in terms of the cancer prevention and aging progression. The DNA damage response (DDR) consists of a complex network controlling the cell cycle and...
Tue Sep 08, 2020 14:29
Related Articles Targeting UDP-glucose dehydrogenase inhibits ovarian cancer growth and metastasis. J Cell Mol Med. 2020 Sep 07;: Authors: Lin LH, Chou HC, Chang SJ, Liao EC, Tsai YT, Wei YS, Chen HY, Lin MW, Wang YS, Chien YA, Yu XR, Chan HL Abstract More than 70% of patients with ovarian cancer are diagnosed in advanced stages. Therefore, it is urgent to identify a promising prognostic marker and understand the mechanism of ovarian cancer...
Tue Sep 08, 2020 14:29
Related Articles [Effect of Huaier aqueous extract on growth and metastasis of human non-small cell lung cancer NCI-H1299 cells and its underlying mechanisms]. Zhongguo Zhong Yao Za Zhi. 2020 Aug;45(15):3700-3706 Authors: Tian YY, Yang AL, Chen XN, Ren HM, Liu YX, Qiu HL, Tang LM, Huang HM, Tu PF, Hu ZD Abstract This study aims to investigate the effect of Huaier aqueous extract on the growth and metastasis of human non-small cell lung...
Tue Sep 08, 2020 14:29
Related Articles Anti-migratory effects of Piper betle leaf aqueous extract on cancer cells and its microtubule targeting properties. J Zhejiang Univ Sci B. 2020 Sept.;21(9):745-748 Authors: Looi ML, Wong AKH, Gnapragasan SA, Japri AZ, Rajedadram A, Pin KY Abstract Piper betle (PB), also known as "betel" in Malay language, is a tropical Asian vine. PB leaves are commonly chewed by Asians along with betel quid. It contains phenols such as...
Tue Sep 08, 2020 14:29
Related Articles Liposome as drug delivery system enhance anticancer activity of iridium (III) complex. J Liposome Res. 2020 Sep 07;:1-46 Authors: Gu Y, Bai L, Zhang Y, Zhang H, Xing D, Tian L, Zhou Y, Hao J, Liu Y Abstract Herein an Ir(III) complex [Ir(Hppy)2(HMNPIP)](PF6) (Ir1, Hppy =2-phenylpyridine, HMNPIP =2-(1H-imidazo[4,5-f][1,10]phenanthroline-3-yl)-6-methoxy-4-nitrophenol) was prepared and characterized. Due to the low anticancer...
Tue Sep 08, 2020 14:29
Related Articles CRM197 reverses paclitaxel resistance by inhibiting the NAC-1/Gadd45 pathway in paclitaxel-resistant ovarian cancer cells. Cancer Med. 2019 10;8(14):6426-6436 Authors: Tang XH, Li H, Zheng XS, Lu MS, An Y, Zhang XL Abstract Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a new promising target for the treatment of ovarian cancer. Our previous study showed that cross-reacting material 197 (CRM197), a...
Tue Sep 08, 2020 14:29
Related Articles Effective Delivery of a Microtubule Polymerization Inhibitor Synergizes with Standard Regimens in Models of Pancreatic Ductal Adenocarcinoma. Clin Cancer Res. 2019 09 15;25(18):5548-5560 Authors: Eberle-Singh JA, Sagalovskiy I, Maurer HC, Sastra SA, Palermo CF, Decker AR, Kim MJ, Sheedy J, Mollin A, Cao L, Hu J, Branstrom A, Weetall M, Olive KP Abstract PURPOSE: Pancreatic ductal adenocarcinoma (PDA) is a deadly cancer that...
Tue Sep 08, 2020 14:29
Related Articles Radio-sensitizing effect of a cocktail of phytochemicals on HepG2 cell proliferation, motility and survival. Biomed Pharmacother. 2020 Sep 03;131:110620 Authors: Abdraboh ME, Essa ZS, Abdelrazzak AB, El-Far YM, Elsherbini Y, El-Zayat MM, Ali DA Abstract Radio-resistance is a major hurdle challenging oncologist worldwide. Despite their anti-cancer characteristics, the implication of phytochemicals in clinical trials is still...
Tue Sep 08, 2020 11:29
Related Articles ERCC6L promotes the progression of hepatocellular carcinoma through activating PI3K/AKT and NF-κB signaling pathway. BMC Cancer. 2020 Sep 05;20(1):853 Authors: Chen H, Wang H, Yu X, Zhou S, Zhang Y, Wang Z, Huang S, Wang Z Abstract BACKGROUND: Excision Repair Cross-Complementation group 6-like (ERCC6L) has been shown to exhibit carcinogenic effect in several malignant tumors. However, the function and molecular mechanism...
Tue Sep 08, 2020 11:29
Abstract Purpose To investigate the effect of 10‐methacryloyloxydecyl dihydrogen phosphate (MDP) concentration in primers on bonding of resin cements to zirconia. Materials and Methods Highly translucent partially stabilized zirconia plates were bonded to stainless steel rods using one of 3 commercially available resin cements without adhesive functional monomers and without air‐abrasion. Ten specimens of each resin cement group were pretreated with one of the primers containing 0.5, 1.0,...
Tue Sep 08, 2020 11:04
Abstract Objective : To evaluate implant and prosthetic survival rates of full‐arch rehabilitations retained by three implants in patients with edentulous mandibles. Methods : This systematic review was developed following the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses statement. The focused question addressed was: Are fixed mandibular 3‐implant retained prostheses safe and predicable for full‐arch mandibular prostheses? The Medline/PubMed and Cochrane Library databases...
Mon Sep 07, 2020 15:23
Related Articles Slow-growing pituitary metastasis from renal cell carcinoma: literature review. World Neurosurg. 2020 Sep 03;: Authors: Moon RDC, Singleton W, Smith P, Urankar K, Evans A, Williams AP Abstract BACKGROUND: Tumour metastasis to the pituitary is rare, most commonly reported with either breast or lung cancer metastasising to the neurohypophysis. Pituitary metastases of renal cell carcinoma (RCC) are by contrast infrequently described...
Tue Sep 08, 2020 14:22
Related Articles Paralysis Caused by Spinal Cord Injury After Posterior Fossa Surgery: A Systematic Review. World Neurosurg. 2020 07;139:151-157 Authors: Yahanda AT, Chicoine MR Abstract OBJECTIVE: Paralysis (paraplegia or quadriplegia) after posterior fossa surgery is a rare but devastating complication. We investigated previous reports of this complication to examine similarities among patients, risk factors, and methods by which it may be...
Tue Sep 08, 2020 14:22
Abstract Background Societal restrictions and lockdown during the COVID‐19 pandemic have had a significant impact on volume and nature of trauma admissions. We assessed the impact of COVID‐19 related societal restrictions and lockdown on trauma admissions to single Level 1 Trauma Center in Westmead, Australia. We hypothesized that the number of trauma admissions would decrease and number of admissions due to self‐harm and assault (specifically domestic violence) would increase. Methods Data...
Mon Sep 07, 2020 16:04
Publication date: Available online 7 September 2020Source: Annals of Diagnostic PathologyAuthor(s): Diana Bell, Achim Bell, Renata Ferrarotto, Bonnie Glisson, Yoko Takahashi, Gregory Fuller, Randal Weber, Ehab Hanna
Tue Sep 08, 2020 14:17
Effect of artifact area on cone beam computed tomography scans when integrated with intraoral scans.
Related Articles Effect of artifact area on cone beam computed tomography scans when integrated with intraoral scans. Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 14;: Authors: Biao Y, Kim DW, Hwang HS, Lee KM Abstract OBJECTIVE: The aim of this study was to examine whether integration accuracy increases upon removing artifacts from the registration area when integrating maxillofacial cone beam computed tomography (CBCT) scans and...
Tue Sep 08, 2020 14:16
Related Articles Is there any predictive bone parameter for implant stability in 2-dimensional and 3-dimensional radiologic images? Oral Surg Oral Med Oral Pathol Oral Radiol. 2020 Aug 18;: Authors: Arsan B, Yalcin-Ülker GM, Meral DG, Erdem TL Abstract OBJECTIVES: This ex vivo study aimed to compare radiomorphometric parameters between 2-dimensional (2-D) and 3-dimensional (3-D) radiographs and evaluate the influence of preoperative radiologic...
Tue Sep 08, 2020 14:16
Publication date: Available online 8 September 2020Source: Radiotherapy and OncologyAuthor(s): Nikhil T. Sebastian, Daniel Trifiletti, Paul D. Brown, Michael Chan, Joshua D. Palmer
Tue Sep 08, 2020 14:10
Publication date: Available online 7 September 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Stanley I. Gutiontov, Daniel W. Golden, Susan McCloskey, Dean Shumway, Donald R. Sullivan, Terry J. Wall, Leonard L. Gunderson, Reshma Jagsi
Tue Sep 08, 2020 13:53
Abstract Recent discoveries of stone tools from Jordan (2.5 Ma) and China (2.1 Ma) document hominin presence in Asia at the beginning of the Pleistocene, well before the conventional Dmanisi datum at 1.8 Ma. Although no fossil hominins documenting this earliest Out of Africa phase have been found, on chronological grounds a pre‐Homo erectus hominin must be considered the most likely maker of those artifacts. If so, this sheds new light on at least two disputed subjects in paleoanthropology, namely...
Mon Sep 07, 2020 14:59
Publication date: Available online 8 September 2020Source: Hearing ResearchAuthor(s): Samuele Carcagno, Christopher J. Plack
Tue Sep 08, 2020 13:44
Related Articles Histopathological effect of pterostilbene as chemoprevention in N-nitroso-tri-chloroethylurea (NTCU)-induced lung squamous cell carcinoma (SCC) mouse model. Histol Histopathol. 2020 Sep 07;:18247 Authors: Surien O, Ghazali AR, Masre SF Abstract BACKGROUND: Lung cancer is the leading cause of cancer-related deaths, and squamous cell carcinoma (SCC) is one of the most common types of lung cancer. Chemoprevention of lung cancer...
Tue Sep 08, 2020 13:41
Related Articles Details of HER2 status in 454 cases of biliary tract cancer. Hum Pathol. 2020 Sep 03;: Authors: Hiraoka N, Nitta H, Ohba A, Yoshida H, Morizane C, Okusaka T, Nara S, Esaki M, Kishi Y, Shimada K Abstract Human epidermal growth factor receptor 2 (HER2)-targeted therapy has improved clinical outcomes in patients with HER2-positive breast and gastric cancers, although ineffective or recurrent cases are present. One reason for this...
Tue Sep 08, 2020 13:39
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18248-4Tissue resident CD8 + T cells present at mucosal surfaces are poised to elicit function in situ, however approaches to boost their number in the gastrointestinal mucosa has been limited. Here the authors combine the use of Listeria monocytogenese and transient depletion of the intestinal microbiome to boost the resident CD8 + T cell response.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18323-wMechanically stable specific heterodimerization formed with reversible bonds are used as a molecular anchorage in single-molecule force spectroscopy studies with unique mechanical properties. Here authors develop a variety of heterodimerization molecular systems with a range of mechanical stability from a set of recently engineered helix-heterotetramers.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18285-zThe delithiation process in lithium excess cathode material of Li2MnO3 has remained unclear. Here, the authors report that delithiation is governed by the climb motion of dislocations with the aid of oxygen-release, determined directly by atomic-resolution STEM imaging and spectroscopy.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18153-wThe source of phospholipids to generate autophagosomal membranes, particularly after prolonged starvation, is not well characterized. Here, the authors show that CCTβ3, the rate limiting enzyme in phosphatidylcholine synthesis, is activated on lipid droplets and sustains long-term autophagy.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-17825-xChronic stress is a risk factor for mood disorders, yet the molecular and circuit mechanisms of stress-induced changes are not well understood. Here, the authors report the role of the transcription factor ΔFosB in driving activity changes in response to stress in glutamatergic neurons in the ventral hippocampus that project to nucleus accumben.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18144-xThough the goal of current organic solid-state laser research remains the realization of electrically pumped lasing, identifying organic semiconductors with ideal properties remains a challenge. Here, the authors report a computational strategy for screening electrical pumping lasing molecules.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18269-zExisting solutions to interface the microwave and optical domains lack either scalability or efficiency. Here, the authors demonstrate a CMOS compatible converter between microwave and optical signals based on silicon an optomechanical device with a total bidirectional transduction efficiency of 1.2% at millikelvin temperatures.
Tue Sep 08, 2020 03:00
Nature Communications, Published online: 08 September 2020; doi:10.1038/s41467-020-18267-1Infection is a growing issue in artificial implants and has become an area of significant interest. Here, the authors report on graphdiyne titanium dioxide composite nanofibres with enhanced photocatalytic reactive oxygen species generation and osteoinductive properties, demonstrated in infected implant models.
Tue Sep 08, 2020 03:00
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