Nutrients, Vol. 12, Pages 2735: Adipose Tissue Development and Expansion from the Womb to Adolescence: An Overview Nutrients doi: 10.3390/nu12092735 Authors: Camila E. Orsso Eloisa Colin-Ramirez Catherine J. Field Karen L. Madsen Carla M. Prado Andrea M. Haqq Prevalence rates of pediatric obesity continue to rise worldwide. Adipose tissue (AT) development and expansion initiate in the fetus and extend throughout the lifespan. This paper presents an overview of the AT developmental...
Nutrients, Vol. 12, Pages 2733: Impact of Storage Conditions on the Breast Milk Peptidome Nutrients doi: 10.3390/nu12092733 Authors: Vanessa Howland Maik Klaedtke Johanna Ruhnau Vishnu M. Dhople Hans J. Grabe Uwe Völker Matthias Heckmann Elke Hammer Human donor milk (HDM) provides appropriate nutrition and offers protective functions in preterm infants. The aim of the study is to examine the impact of different storage conditions on the stability of the human breast...
Nutrients, Vol. 12, Pages 2734: Effects of Dietary Nitrates on Time Trial Performance in Athletes with Different Training Status: Systematic Review Nutrients doi: 10.3390/nu12092734 Authors: Tomáš Hlinský Michal Kumstát Petr Vajda Much research has been done in sports nutrition in recent years as the demand for performance-enhancing substances increases. Higher intake of nitrates from the diet can increase the bioavailability of nitric oxide (NO) via the nitrate–nitrite–NO...
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Pathogens, Vol. 9, Pages 738: Mayaro Virus Pathogenesis and Transmission Mechanisms Pathogens doi: 10.3390/pathogens9090738 Authors: Cheikh Tidiane Diagne Michèle Bengue Valérie Choumet Rodolphe Hamel Julien Pompon Dorothée Missé Mayaro virus (MAYV), isolated for the first time in Trinidad and Tobago, has captured the attention of public health authorities worldwide following recent outbreaks in the Americas. It has a propensity to be exported outside its original geographical...
Pathogens, Vol. 9, Pages 737: Control Measures for SARS-CoV-2: A Review on Light-Based Inactivation of Single-Stranded RNA Viruses Pathogens doi: 10.3390/pathogens9090737 Authors: Joshua Hadi Magdalena Dunowska Shuyan Wu Gale Brightwell SARS-CoV-2 is a single-stranded RNA virus classified in the family Coronaviridae. In this review, we summarize the literature on light-based (UV, blue, and red lights) sanitization methods for the inactivation of ssRNA viruses in different matrixes...
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Pharmaceuticals, Vol. 13, Pages 237: Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists Pharmaceuticals doi: 10.3390/ph13090237 Authors: Jinfeng Zhang Wenzhong Yan Wenwen Duan Kurt Wüthrich Jianjun Cheng The A2A adenosine receptor (A2AAR) plays critical roles in human physiology and pathophysiology, which makes it an important drug target. Previous drug-discovery efforts targeting the A2AAR have been focused on the use of A2AAR antagonists for the treatment of Parkinson’s...
Pharmaceuticals, Vol. 13, Pages 236: The Role of Adaptogens in Prophylaxis and Treatment of Viral Respiratory Infections Pharmaceuticals doi: 10.3390/ph13090236 Authors: Alexander Panossian Thomas Brendler The aim of our review is to demonstrate the potential of herbal preparations, specifically adaptogens for prevention and treatment of respiratory infections, as well as convalescence, specifically through supporting a challenged immune system, increasing resistance to viral infection,...
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Pharmaceutics, Vol. 12, Pages 854: Development of Theranostic Cationic Liposomes Designed for Image-Guided Delivery of Nucleic Acid Pharmaceutics doi: 10.3390/pharmaceutics12090854 Authors: Hai Doan Do Christine Ménager Aude Michel Johanne Seguin Tawba Korichi Hélène Dhotel Corinne Marie Bich-Thuy Doan Nathalie Mignet Cationic liposomes have been considered as potential vectors for gene delivery thanks to their ability to transfect cells with high efficiency....
Pharmaceutics, Vol. 12, Pages 853: Pharmaceutical Application of Tablet Film Coating Pharmaceutics doi: 10.3390/pharmaceutics12090853 Authors: Ki-Soo Seo Rajiv Bajracharya Sang Hoon Lee Hyo-Kyung Han Tablet film coating is a common but critical process providing various functionalities to tablets, thereby meeting diverse clinical needs and increasing the value of oral solid dosage forms. Tablet film coating is a technology-driven process and the evolution of coated dosage forms...
Pharmaceutics, Vol. 12, Pages 852: Acute and Chronic Dosing of a High-Affinity Rat/Mouse Chimeric Transferrin Receptor Antibody in Mice Pharmaceutics doi: 10.3390/pharmaceutics12090852 Authors: Demi M. Castellanos Jiahong Sun Joshua Yang Weijun Ou Alexander C. Zambon William M. Pardridge Rachita K. Sumbria Non-invasive brain delivery of neurotherapeutics is challenging due to the blood-brain barrier. The revived interest in transferrin receptor antibodies (TfRMAbs)...
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Plants, Vol. 9, Pages 1163: QTL Mapping and Candidate Gene Analysis for Pod Shattering Tolerance in Soybean (Glycine max) Plants doi: 10.3390/plants9091163 Authors: Jeong-Hyun Seo Beom-Kyu Kang Sanjeev K. Dhungana Jae-Hyeon Oh Man-Soo Choi Ji-Hee Park Sang-Ouk Shin Hong-Sik Kim In-Youl Baek Jung-Sook Sung Chan-Sik Jung Ki-Seung Kim Tae-Hwan Jun Pod shattering is an important reproductive process in many wild species. However, pod shattering at the...
Plants, Vol. 9, Pages 1161: Chemical Compounds, Pharmacological and Toxicological Activity of Brugmansia suaveolens: A Review Plants doi: 10.3390/plants9091161 Authors: Vera L. Petricevich David Osvaldo Salinas-Sánchez Dante Avilés-Montes Cesar Sotelo-Leyva Rodolfo Abarca-Vargas This study investigates updated information in different search engines on the distribution, phytochemistry, pharmacology, and toxicology of Brugmansia suaveolens (Solanaceae) using the extracts or...
Plants, Vol. 9, Pages 1160: Integrating Multiple Lines of Evidence to Explore Intraspecific Variability in a Rare Endemic Alpine Plant and Implications for its Conservation Plants doi: 10.3390/plants9091160 Authors: Martino Adamo Stefano Mammola Virgile Noble Marco Mucciarelli We studied the ecology, distribution, and phylogeography of Tephroseris balbisiana, a rare plant whose range is centered to the South-Western Alps. Our aim was to assess the extent of intraspecific variability...
Plants, Vol. 9, Pages 1162: Gene Expression Profiles and Flavonoid Accumulation during Salt Stress in Ginkgo biloba Seedlings Plants doi: 10.3390/plants9091162 Authors: Ningtao Xu Sian Liu Zhaogeng Lu Siyu Pang Lu Wang Li Wang Weixing Li Ginkgo biloba is an economically valuable tree, as a variety of flavonoid compounds are produced by the leaves of its seedlings. Although soil salinity is a serious threat to agricultural productivity worldwide, the effect of salt stress...
Plants, Vol. 9, Pages 1158: The Roles of Cytokinins in Plants and Their Response to Environmental Stimuli Plants doi: 10.3390/plants9091158 Authors: R. J. Neil Emery Anna Kisiala Cytokinins (CKs) are adenine-derived, small-molecule plant growth regulators that control aspects of almost all plant growth and development processes. Internally, CKs play significant roles in plant cell division, nutrient allocation, and photosynthetic performance, and they are also detection and signaling...
Plants, Vol. 9, Pages 1157: Aerobic Barley Mg-protoporphyrin IX Monomethyl Ester Cyclase is Powered by Electrons from Ferredoxin Plants doi: 10.3390/plants9091157 Authors: David Stuart Malin Sandström Helmy M. Youssef Shakhira Zakhrabekova Poul Erik Jensen David W. Bollivar Mats Hansson Chlorophyll is the light-harvesting molecule central to the process of photosynthesis. Chlorophyll is synthesized through 15 enzymatic steps. Most of the reactions have been characterized...
Plants, Vol. 9, Pages 1159: A Narrow Endemic or a Species Showing Disjunct Distribution? Studies on Meehania montis-koyae Ohwi (Lamiaceae) Plants doi: 10.3390/plants9091159 Authors: Atsuko Takano Shota Sakaguchi Pan Li Ayumi Matsuo Yoshihisa Suyama Guo-Hua Xia Xi Liu Yuji Isagi Meehania montis-koyae Ohwi (Lamiaceae), which has been considered a narrow endemic and endangered species in Japan, was found in eastern China in 2011. China and Japan belong to the same floristic...
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Publications, Vol. 8, Pages 43: Research Contribution of the Oldest Seat of Higher Learning in Pakistan: A Bibliometric Analysis of University of the Punjab Publications doi: 10.3390/publications8030043 Authors: Shakil Ahmad Javed Hussain Khahro Shahid Bibliometric methods are used to access various elements in any data set. Similarly, this study uses a bibliometric method to evaluate the research performance of the University of the Punjab (PU), the oldest university of...
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Religions, Vol. 11, Pages 460: Construction and Evaluation of an Educational Video: Nursing Assessment and Intervention of Patients’ Spiritual Needs Religions doi: 10.3390/rel11090460 Authors: Juliane Cristina Rodrigues Talita Prado Simão Miranda Francine Lima Fulquini Caroline Guilherme Sílvia Caldeira Emilia Campos de Carvalho Spirituality is particularly important in health and illness transitions and is a fundamental dimension of healthcare. However, nurses often feel...
Religions, Vol. 11, Pages 459: The Hebrew Bible as Mythic “Vocabulary”: Towards a New Comparative Mythology Religions doi: 10.3390/rel11090459 Authors: Andrew Tobolowsky In this article, I argue that the history of the study of myth in the Hebrew Bible has been, and continues to be, shaped in negative ways by an essentially Romantic Nationalist understanding of the relationship between a people and their traditions. I then argue that more appropriate ways of modeling the construction...
Religions, Vol. 11, Pages 458: Ritualizing Pregnancy and Childbirth in Secular Societies: Exploring Embodied Spirituality at the Start of Life Religions doi: 10.3390/rel11090458 Authors: Joanna Wojtkowiak Birth is the beginning of a new life and therefore a unique life event. In this paper, I want to study birth as a fundamental human transition in relation to existential and spiritual questions. Birth takes place within a social and cultural context. A new member of society is entering...
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Risks, Vol. 8, Pages 95: Least Quartic Regression Criterion to Evaluate Systematic Risk in the Presence of Co-Skewness and Co-Kurtosis Risks doi: 10.3390/risks8030095 Authors: Giuseppe Arbia Riccardo Bramante Silvia Facchinetti This article proposes a new method for the estimation of the parameters of a simple linear regression model which is based on the minimization of a quartic loss function. The aim is to extend the traditional methodology, based on the normality assumption,...
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Safety, Vol. 6, Pages 41: “We Force Ourselves”: Productivity, Workplace Culture, and HRI Prevention in Florida’s Citrus Groves Safety doi: 10.3390/safety6030041 Authors: Maria C. Morera Cody Gusto Paul F. Monaghan José Antonio Tovar-Aguilar Fritz M. Roka Efforts to disseminate heat-related illness (HRI) prevention practices among Latino farmworkers represent a critical occupational safety strategy in Florida. Targeted initiatives, however, require understanding the workplace...
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Sci, Vol. 2, Pages 70: Advancing Therapies for Cancer—From Mustard Gas to CAR T Sci doi: 10.3390/sci2030070 Authors: Dillon K Jarrell Seth Drake Mark A Brown The development of targeted therapeutics for cancer continues to receive intense research attention as laboratories and pharmaceutical companies seek to develop drugs and technologies that improve treatment efficacy and mitigate harmful side effects. In the aftermath of World War I, it was discovered that mustard gas destroys...
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Smart Cities, Vol. 3, Pages 978-1003: Replicating Smart Cities: The City-to-City Learning Programme in the Replicate EC-H2020-SCC Project Smart Cities doi: 10.3390/smartcities3030049 Authors: Igor Calzada This article addresses the problem of replication among smart cities in the European Commission’s Horizon 2020: Smart Cities and Communities (EC-H2020-SCC) framework programme. This article initially sets the general policy context by conducting a benchmarking about the explicit...
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Sports, Vol. 8, Pages 124: Isokinetic Dynamometry as a Tool to Predict Shoulder Injury in an Overhead Athlete Population: A Systematic Review Sports doi: 10.3390/sports8090124 Authors: Andrea Bagordo Kimberly Ciletti Kevin Kemp-Smith Vini Simas Mike Climstein James Furness Prospective and cross-sectional studies have used pre-season isokinetic dynamometry strength and endurance measurements of shoulder internal rotation (IR) and external rotation (ER) to determine if they...
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Toxins, Vol. 12, Pages 577: Exploring Emotional Distress, Psychological Traits and Attitudes in Patients with Chronic Migraine undergoing OnabotulinumtoxinA Prophylaxis versus Withdrawal Treatment Toxins doi: 10.3390/toxins12090577 Authors: Donisi Mazzi Gandolfi Deledda Marchioretto Battista Poli Giansante Geccherle Perlini Smania Del Piccolo This explorative cross-sectional study aims at exploring emotional distress, psychological profiles,...
Toxins, Vol. 12, Pages 576: Venom Ophthalmia and Ocular Complications Caused by Snake Venom Toxins doi: 10.3390/toxins12090576 Authors: Kun-Che Chang Yu-Kai Huang Yen-Wen Chen Min-Hui Chen Anthony T. Tu Yen-Chia Chen Little is known about the detailed clinical description, pathophysiology, and efficacy of treatments for ocular envenoming (venom ophthalmia) caused by venom of the spitting elapid and other snakes, as well as ocular complications caused by snake venom injection....
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Vaccines, Vol. 8, Pages 512: Increasing Measles Seroprevalence in a Sample of Pediatric and Adolescent Population of Tuscany (Italy): A Vaccination Campaign Success Vaccines doi: 10.3390/vaccines8030512 Authors: Beatrice Zanella Sara Boccalini Benedetta Bonito Marco Del Riccio Emilia Tiscione Paolo Bonanni Working Group DHS Working Group DHS Working Group AOUMeyer Working Group AOUMeyer Working Group AUSLTC Working Group AUSLTC Angela Bechini Background: Despite...
Vaccines, Vol. 8, Pages 514: Healthcare Workers Training Courses on Vaccinations: A Flexible Format Easily Adaptable to Different Healthcare Settings Vaccines doi: 10.3390/vaccines8030514 Authors: Laura Serino Massimo Maurici Gian Loreto D’Alò Fabiana Amadori Elisa Terracciano Laura Zaratti Elisabetta Franco Local Health Units Vaccination Group Since 2017, Italy has expanded the compulsory vaccination from 4 to 10 for those aged 0 to 16 years. Because of the great...
Vaccines, Vol. 8, Pages 511: A Zigzag but Upward Way to Develop an HIV-1 Vaccine Vaccines doi: 10.3390/vaccines8030511 Authors: Ziyu Wen Caijun Sun After decades of its epidemic, the human immunodeficiency virus type 1 (HIV-1) is still rampant worldwide. An effective vaccine is considered to be the ultimate strategy to control and prevent the spread of HIV-1. To date, hundreds of clinical trials for HIV-1 vaccines have been tested. However, there is no HIV-1 vaccine available yet,...
Vaccines, Vol. 8, Pages 510: LvYY1 Activates WSSV ie1 Promoter for Enhanced Vaccine Production and Efficacy Vaccines doi: 10.3390/vaccines8030510 Authors: Li-Na Tao Ze-Hui Liu Hui-Ling Xu Ying Lu Min Liao Fang He The baculovirus expression vector system (BEVS) has been used as a preferred platform for the production of recombinant protein complexes and efficacious vaccines. However, limited protein yield hinders the application of BEVS. It is well accepted that transcription...
Vaccines, Vol. 8, Pages 513: Association of Porcine Swine Leukocyte Antigen (SLA) Haplotypes with B- and T-Cell Immune Response to Foot-and-Mouth Disease Virus (FMDV) Peptides Vaccines doi: 10.3390/vaccines8030513 Authors: Patricia de León Rodrigo Cañas-Arranz Yago Saez Mar Forner Sira Defaus Dolores Cuadra María J. Bustos Elisa Torres David Andreu Esther Blanco Francisco Sobrino Sabine E. Hammer Dendrimer peptides are promising vaccine candidates against...
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Veterinary Sciences, Vol. 7, Pages 131: Seasonality of Nosema ceranae Infections and Their Relationship with Honey Bee Populations, Food Stores, and Survivorship in a North American Region Veterinary Sciences doi: 10.3390/vetsci7030131 Authors: Berna Emsen Alvaro De la Mora Brian Lacey Les Eccles Paul G. Kelly Carlos A. Medina-Flores Tatiana Petukhova Nuria Morfin Ernesto Guzman-Novoa Nosema ceranae is an emerging pathogen of the western honey bee (Apis mellifera...
Veterinary Sciences, Vol. 7, Pages 132: Sheep Brucellosis in Kuwait: A Large-Scale Serosurvey, Identification of Brucella Species and Zoonotic Significance Veterinary Sciences doi: 10.3390/vetsci7030132 Authors: Al-Sherida El-Gohary Mohamed El-Diasty Wareth Neubauer Abdelkhalek Brucellosis is a common zoonotic disease of major concern in humans of Kuwait, and B. melitensis causes most human cases. The disease is endemic in small ruminants, cattle, and camels...
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Viruses, Vol. 12, Pages 1004: Infection of Brain Organoids and 2D Cortical Neurons with SARS-CoV-2 Pseudovirus Viruses doi: 10.3390/v12091004 Authors: Sang Ah Yi Ki Hong Nam Jihye Yun Dongmin Gim Daeho Joe Yong Ho Kim Han-Joo Kim Jeung-Whan Han Jaecheol Lee Since the global outbreak of SARS-CoV-2 (COVID-19), infections of diverse human organs along with multiple symptoms continue to be reported. However, the susceptibility of the brain to SARS-CoV-2, and the mechanisms...
Viruses, Vol. 12, Pages 1000: Prevalence of Feline Coronavirus Shedding in German Catteries and Associated Risk Factors Viruses doi: 10.3390/v12091000 Authors: Ute Klein-Richers Katrin Hartmann Regina Hofmann-Lehmann Stefan Unterer Michèle Bergmann Anna Rieger Christian Leutenegger Nikola Pantchev Jörg Balzer Sandra Felten The aim of this prospective study was to determine prevalence and potential risk factors of feline coronavirus (FCoV) shedding. Four consecutive...
Viruses, Vol. 12, Pages 1002: Defining New Pathways to Manage the Ongoing Emergence of Bat Rabies in Latin America Viruses doi: 10.3390/v12091002 Authors: Julio A. Benavides William Valderrama Sergio Recuenco Wilson Uieda Gerardo Suzán Rafael Avila-Flores Andres Velasco-Villa Marilene Almeida Fernanda A.G. de Andrade Baldomero Molina-Flores Marco Antonio Natal Vigilato Julio Cesar Augusto Pompei Paolo Tizzani Jorge E. Carrera Darcy Ibanez Daniel...
Viruses, Vol. 12, Pages 1001: A Comprehensive Study of Cutaneous Fibropapillomatosis in Free-Ranging Roe Deer (Capreolus capreolus) and Red Deer (Cervus elaphus): from Clinical Manifestations to Whole-Genome Sequencing of Papillomaviruses Viruses doi: 10.3390/v12091001 Authors: Jernej Kmetec Urška Kuhar Aleksandra Grilc Fajfar Diana Žele Vengušt Gorazd Vengušt Papillomaviruses (PVs) are an extremely large group of viruses that cause skin and mucosa infections in humans and...
Viruses, Vol. 12, Pages 1003: Maternal Influenza A Virus Infection Restricts Fetal and Placental Growth and Adversely Affects the Fetal Thymic Transcriptome Viruses doi: 10.3390/v12091003 Authors: Van Campen Bishop Abrahams Bielefeldt-Ohmann Mathiason Bouma Winger Mayo Bowen Hansen Maternal influenza A viral infections in humans are associated with low birth weight, increased risk of pre-term birth, stillbirth and congenital defects. To examine the...
Viruses, Vol. 12, Pages 999: Equine Herpesvirus Type 1 Modulates Cytokine and Chemokine Profiles of Mononuclear Cells for Efficient Dissemination to Target Organs Viruses doi: 10.3390/v12090999 Authors: Pavulraj Kamel Stephanowitz Liu Plendl Osterrieder Azab Equine herpesvirus type 1 (EHV-1) causes encephalomyelopathy and abortion, for which cell-associated viremia and subsequent virus transfer to and replication in endothelial cells (EC) are responsible and...
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Water, Vol. 12, Pages 2507: Improved Short-Term Microbial Degradation in Circulating Water Reducing High Stagnant Atrazine Concentrations in Subsurface Sediments Water doi: 10.3390/w12092507 Authors: Xinxin Liu Nan Hui Merja H. Kontro The triazine herbicide atrazine easily leaches with water through soil layers into groundwater, where it is persistent. Its behavior during short-term transport is poorly understood, and there is no in situ remediation method for it. The aim of this...
Water, Vol. 12, Pages 2505: Assessing Inter-Administrative Cooperation in Urban Public Services: A Case Study of River Municipalities in the Internal Border Area between Aragon and Catalonia (Spain) Water doi: 10.3390/w12092505 Authors: Santasusagna Riu Caldés Donada The proper management of urban public services (UPS) ensures that a territory functions efficiently, since it guarantees optimal waste disposal, water supply, and the maintenance of communication infrastructure,...
Water, Vol. 12, Pages 2506: Cambodian Freshwater Fish Assemblage Structure and Distribution Patterns: Using a Large-Scale Monitoring Network to Understand the Dynamics and Management Implications of Species Clusters in a Global Biodiversity Hotspot Water doi: 10.3390/w12092506 Authors: Pin Nut Hogan Chandra Saray Touch Chheng Ngor Mekong River Basin is one of the world’s fish biodiversity hotspots. Fisheries of the Cambodian Mekong are characterized...
Water, Vol. 12, Pages 2504: Coastal Engineers Embrace Nature: Characterizing the Metamorphosis in Hydraulic Engineering in Terms of Four Continua Water doi: 10.3390/w12092504 Authors: Jill H. Slinger Heleen S. I. Vreugdenhil Hydraulic engineering infrastructures, such as reservoirs, dikes, breakwaters, and inlet closures, have significantly impacted ecosystem functioning over the last two centuries. Currently, nature-based solutions are receiving increasing attention in hydraulic...
Water, Vol. 12, Pages 2503: Minor Imbalance of the Lowermost Italian Glacier from 2006 to 2019 Water doi: 10.3390/w12092503 Authors: De Marco Carturan Piermattei Cucchiaro Moro Dalla Fontana Cazorzi The response of very small glaciers to climate changes is highly scattered and little known in comparison with larger ice bodies. In particular, small avalanche-fed and debris-covered glaciers lack mass balance series of sufficient length. In this paper we present...
Water, Vol. 12, Pages 2501: Review of Methods to Repair and Maintain Lithophilic Fish Spawning Habitat Water doi: 10.3390/w12092501 Authors: Audrey Baetz Taaja R. Tucker Robin L. DeBruyne Alex Gatch Tomas Höök Jason L. Fischer Edward F. Roseman Rocky reefs provide important spawning and refuge habitats for lithophilic spawning fishes. However, many reefs have been lost or severely degraded through anthropogenic effects like dredging, channelization, or sedimentation....
Water, Vol. 12, Pages 2502: Precipitation Characteristics of an Abrupt Heavy Rainfall Event over the Complex Terrain of Southwest China Observed by the FY-4A Satellite and Doppler Weather Radar Water doi: 10.3390/w12092502 Authors: Shanshan Li Guoping Li Xiaofang Wang Chao Li Haizhi Liu Gang Li On 22 July 2019, mesoscale convective systems (MCSs) with an abrupt heavy rainfall event (AHRE) hit Shuicheng County of Guizhou Province in Southwest China causing landslide and...
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