Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
Tue Sep 01, 2020 10:00
Pediatric Allergy, Immunology, and Pulmonology, Ahead of Print.
Tue Sep 01, 2020 10:00
Surgical Infections, Ahead of Print.
Tue Sep 01, 2020 10:00
Chromosome level assemblies are accumulating in various taxonomic groups including mosquitoes. However, even in the few reference-quality mosquito assemblies, a significant portion of the heterochromatic regions including telomeres remain unresolved. Here we produce a de novo assembly of the New World malaria mosquito, Anopheles albimanus by integrating Oxford Nanopore sequencing, Illumina, Hi-C and optical mapping. This 172.6 Mbps female assembly, which we call AalbS3, is obtained by scaffolding...
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In many organisms, tissue complexity and cellular diversity create a barrier that can hinder our understanding of gene expression programs. To address this problem, methods have been developed that allow for easy isolation of translated mRNAs from genetically defined cell populations. A prominent example is the Translating Ribosome Affinity Purification method also called TRAP. Here, ribosome associated mRNAs are isolated via purification of the ribosomal protein RPL10A/uL1, which is expressed under...
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Abstract Background Complications mean a recurring problem in everyday clinical practice. Complication rates between 6 and 13% are described for the treatment of bony injuries to the head and neck area. This paper aims to provide a detailed analysis of the complications after osteosynthesis in facial skull fractures. Material and method In this retrospective...
Thu Sep 03, 2020 03:00
Heterogeneous Presentations of Pharyngoesophageal Diverticula Occurring after Cervical Spine Surgery
Abstract Dysphagia after anterior cervical spine surgery (ACSS) may be secondary to pharyngoesophageal diverticulum. Our objectives are to (1) highlight the heterogeneity in clinical presentation, (2) discuss pathophysiology and management, and (3) present a comprehensive literature review of these diverticula. All patients undergoing pharyngoesophageal diverticulum repair between 2013 and 2019 were identified. Cases with ACSS history underwent detailed review of clinical presentation,...
Thu Sep 03, 2020 03:00
Horm Metab ResDOI: 10.1055/a-1236-4869Primary hyperaldosteronism (PA) is a well-known cause of hypertension although its exact prevalence amongst patients with apparent essential hypertension has been a matter of debate. A number of recent studies have suggested that mild forms of PA may be relatively common taking into consideration factors that were previously either overestimated or ignored when developing...
Thu Sep 03, 2020 02:00
Introduction: Stapes surgery is a safe procedure, with favourable hearing outcome. The objective of the study is to assess the long-term hearing results, addressing the bone conduction (BC) decay and the need for hearing aids in otosclerosis patients. Methods: We enrolled patients who underwent stapes surgery by means of stapedectomy or stapedotomy between 1991 and 2001. All enrolled patients underwent pure-tone audiometry (PTA) between September 2017 and June 2018. A set of questions was administered...
Thu Sep 03, 2020 12:17
Abstract Purpose Prostate-specific membrane antigen (PSMA) is not only highly expressed on the surface prostate cancer cells but is also elevated during angiogenesis in other cancer cell types, including hepatocellular carcinoma (HCC). This study aimed to evaluate the feasibility of using PET/CT imaging with [68Ga]Ga-PSMA-11 in HCC and its impact on patient management. ...
Thu Sep 03, 2020 03:00
Abstract The coronavirus disease (COVID-19) pandemic has brought critical challenges to anesthesiologists and perioperative practice. Whereas anesthesiologists may be primarily concerned with airway and respiratory management, the COVID-19 data accumulated to date indicate that primary and/or secondary cardiovascular complications are common. Previous studies have demonstrated that the mortality rate is significantly higher in patients with cardiovascular disease (CVD) than in...
Thu Sep 03, 2020 03:00
Summary Primary effusion lymphoma (PEL), caused by Kaposi’s sarcoma-associated herpesvirus (KSHV), presents as a lymphomatous effusion in body cavities and has a poor prognosis. The anti-malaria drug, artesunate, possesses anti-neoplastic potential. Therefore, we aimed to investigate its effect on KSHV-infected PEL cell lines. Artesunate inhibited cell growth and viability of PEL cells, but its effect on peripheral blood mononuclear cells was less pronounced. Artesunate induced...
Thu Sep 03, 2020 03:00
Abstract Several insect endosymbionts have evolved to become plant pathogens, but the causes of this transition are currently unknown. In this paper, we use adaptive dynamics to develop hypotheses to explain why an insect endosymbiont would evolve to become a plant pathogen. We develop a model of facultative insect endosymbionts, capable of both vertical transmission within the insect population and horizontal transmission between insect and plant populations. We assume that an...
Thu Sep 03, 2020 03:00
Some male butterflies seal their mate's genitalia with a waxy 'chastity belt' to prevent future liaisons. But female butterflies can fight back. Could this sexual one-upmanship ultimately result in new species?
Thu Sep 03, 2020 22:55
Related Articles MiR-24 Promotes Cell Growth in Human Glioma by CDX1/PI3K/Akt Signaling Pathway. Cancer Biother Radiopharm. 2020 Sep 01;: Authors: Lei D, Sun H, Zhang B Abstract MicroRNA-24 (miR-24) has been identified to be related to the development of glioma. However, the exact molecular mechanism of miR-24 in glioma progression remains vague. The aim of the present study was to investigate the role of miR-24 in sepsis and to reveal the associated...
Thu Sep 03, 2020 22:50
Related Articles Optimization and Evaluation of Poly(lactide-co-glycolide) Nanoparticles for Enhanced Cellular Uptake and Efficacy of Paclitaxel in the Treatment of Head and Neck Cancer. Pharmaceutics. 2020 Aug 30;12(9): Authors: Haider M, Elsherbeny A, Jagal J, Hubatová-Vacková A, Saad Ahmed I Abstract The particle size (PS) and encapsulation efficiency (EE%) of drug-loaded nanoparticles (NPs) may inhibit their cellular uptake and lead to possible...
Thu Sep 03, 2020 22:50
Related Articles A Relationship Between Cervical Vertebrae Twisting and Cranial Angle in Head and Neck Radiotherapy. In Vivo. 2020 Sep-Oct;34(5):2401-2406 Authors: Aoyama T, Shimizu H, Sasaki K, Ando M, Kaneda N, Tachibana H, Suzuki K, Kodaira T Abstract BACKGROUND/AIM: Because current image-guided radiotherapy systems can only correct six axes, it is impossible to correct the twisting of cervical vertebrae. The purpose of this study was to...
Thu Sep 03, 2020 22:50
Related Articles Collagenase Nanoparticles Enhance the Penetration of Drugs into Pancreatic Tumors. ACS Nano. 2019 10 22;13(10):11008-11021 Authors: Zinger A, Koren L, Adir O, Poley M, Alyan M, Yaari Z, Noor N, Krinsky N, Simon A, Gibori H, Krayem M, Mumblat Y, Kasten S, Ofir S, Fridman E, Milman N, Lübtow MM, Liba L, Shklover J, Shainsky-Roitman J, Binenbaum Y, Hershkovitz D, Gil Z, Dvir T, Luxenhofer R, Satchi-Fainaro R, Schroeder A Abstract ...
Thu Sep 03, 2020 22:50
Related Articles Reconstruction of mandibular bone defects using biphasic calcium phosphate bone substitutes with simultaneous implant placement in mini-swine: A pilot in vivo study. J Biomed Mater Res B Appl Biomater. 2019 08;107(6):2071-2079 Authors: Zhang Z, Wang P, Li X, Wang Y, Qin Z, Zhang C, Li J Abstract This study aimed to investigate implant osseointegration using a new strategy of biphasic calcium phosphate (BCP) bone substitutes...
Thu Sep 03, 2020 22:50
A few weeks ago, the Association of Latina/o & Latinx Anthropologists (ALLA) released a statement condemning anti-Black violence and calling for “an intimate reckoning with anti-Blackness and white supremacy that pervades our communities.” Such actions necessitate going beyond words of solidarity, like the phrase “Latinos for Black Lives,” which reinforce a commonsense of whiteness implicit in colonial projects. If we are to reject anti-Black racism, then we must take seriously Lorgia García...
Thu Sep 03, 2020 21:30
Publication date: Available online 3 September 2020Source: Journal of VoiceAuthor(s): Sarah Nyirjesy, Peyton Osmundson, Laura Matrka
Thu Sep 03, 2020 21:46
Publication date: Available online 3 September 2020Source: Journal of VoiceAuthor(s): Frank W. Ragsdale, Judy O. Marchman, Michelle M. Bretl, Jennylee Diaz, David E. Rosow, Mursalin Anis, Hang Zhang, Mario A. Landera, Adam T. Lloyd
Thu Sep 03, 2020 21:46
Publication date: Available online 3 September 2020Source: Journal of VoiceAuthor(s): Lauren H. Allison, Grace M. Cutchin, Emily N. Snell, Mary J. Sandage
Thu Sep 03, 2020 21:46
Related Articles Determination of the Relationships Between intra- and Extraoral Tongue Hardness, Thickness, and Pressure Using Ultrasonic Elastography. Dysphagia. 2020 Sep 01;: Authors: Miura K, Ohkubo M, Sugiyama T, Tsuiki M, Ishida R Abstract Involved with various bodily functions, including ingestion and swallowing, the tongue is an important organ. We measured resting tongue hardness using real-time tissue elastography (RTE) to establish...
Thu Sep 03, 2020 21:34
Related Articles Simultaneous double balloon dilatation using double channel therapeutic endoscope in patients with cricopharyngeal muscle dysfunction: An observative study. Medicine (Baltimore). 2020 Aug 28;99(35):e21793 Authors: Jo YS, Cha JH, Kim YK, Kim SY, Lee HS Abstract The role of endoscopic balloon dilatation (EBD) using double-balloon catheters in patients with cricopharyngeal muscle dysfunction (CPD) is still unclear. Thus, the aim...
Thu Sep 03, 2020 21:34
Related Articles Advanced MRI of Spinal Lesions. Radiology. 2020 Sep 01;:203025 Authors: Haller S PMID: 32876541 [PubMed - as supplied by publisher]
Thu Sep 03, 2020 21:08
Related Articles Multimodality Imaging for More Accurate Diagnosis and Risk Assessment in Infective Endocarditis. Radiology. 2020 Sep 01;:203115 Authors: Sakuma H PMID: 32876540 [PubMed - as supplied by publisher]
Thu Sep 03, 2020 21:08
Related Articles Breast Lumps in Lactating Women: US May Be Enough. Radiology. 2020 Sep 01;:203253 Authors: Newell MS PMID: 32876539 [PubMed - as supplied by publisher]
Thu Sep 03, 2020 21:08
Publication date: Available online 2 September 2020Source: Sleep MedicineAuthor(s): Lynn Marie Trotti, Jason C. Ong, David T. Plante, Catherine Friederich Murray, Rebecca King, Donald L. Bliwise
Thu Sep 03, 2020 21:07
Aim. To evaluate the prognostic significance of C-reactive protein to albumin ratio (CAR) for clinical outcomes in hepatocellular carcinoma (HCC) patients. Material and Methods. Eligible studies were searched by PubMed, MedLine, the Cochrane Library, from January 1, 2000, to June 30, 2019, investigating the prognostic value of CAR in patients with HCC. Primary endpoint was OS. Hazard ratio (HR) with 95% confidence interval (CI) was used to determine the effect size. Results. 7 records including 2208...
Thu Sep 03, 2020 16:20
6,12-Diphenyl-3,9-diazatetraasterane-1, 5, 7, 11-tetracarboxylate (DDTC) has been synthesized by the photodimerization of 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate. The potential of theercvantitumor activity and mechanism were investigated in vitro using MTT assay in human lung cancer cell line A549, ovarian cancer cell lines SKOV3 and A2780, breast cancer cell line MCF-7, gastric cancer cell line BGC-823, colon cancer cell line HT29, prostate cancer cell line DU145, and liver cancer cell line...
Thu Sep 03, 2020 14:50
A new study published in Current Biology reveals that the ability for humans to digest milk (lactase persistence) spread through Central Europe quickly in evolutionary terms.
Thu Sep 03, 2020 18:42
Abstract Purpose Lenvatinib (LEN) has been approved for the treatment of patients with progressive radioiodine-refractory differentiated thyroid cancer (RAI-R DTC). Real-life studies reported a lower progression-free survival (PFS) than the registration study, likely due to the more advanced stage of tumors, the more frequent pretreatment with other TKIs, the limited follow-up, and the worse clinical condition of the patients included....
Thu Sep 03, 2020 03:00
Abstract Purpose Despite a biological plausibility of a direct link between low vitamin D and androgen deficiency, the association remains inconclusive in epidemiological studies. Therefore, this systematic review and meta-analysis of case-control studies aim to assess whether and in what populations such an association can be demonstrated. Methods ...
Thu Sep 03, 2020 03:00
Abstract Purpose The aim of this study was to compare phenotype of patients with pituitary, adrenal and ectopic CS and identify the differences regarding biochemical parameters, clinical presentations, and comorbidities in CS patients who were diagnosed at the single endocrinological center in Wroclaw. Methods The study population involved 64 patients...
Thu Sep 03, 2020 03:00
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