Cancers, Vol. 11, Pages 1693: How Do Synchronous Lung Metastases Influence the Surgical Management of Children with Hepatoblastoma? An Update and Systematic Review of the Literature Cancers doi: 10.3390/cancers11111693 Authors: Roberta Angelico Chiara Grimaldi Carlo Gazia Maria Cristina Saffioti Tommaso Maria Manzia Aurora Castellano Marco Spada Approximately 20% of children with hepatoblastoma (HB) have metastatic disease at diagnosis, most frequently in the lungs....
Thu Oct 31, 2019 02:00
Cancers, Vol. 11, Pages 1694: Improved Anti-Tumour Adaptive Immunity Can Overcome the Melanoma Immunosuppressive Tumour Microenvironment Cancers doi: 10.3390/cancers11111694 Authors: Nana Dang Mark Waer Ben Sprangers Yuan Lin Clinical benefits obtained from checkpoint blockade regimens demonstrate the importance of overcoming the immunosuppressive tumour microenvironment (TME) in cancer immunotherapy. Intravenous (i.v.) injection of B16 melanoma cells (H-2Kb) leads to lethal...
Thu Oct 31, 2019 02:00
Breast radiotherapy using a breast cup: moving the target, not the patient.: Breast cup radiotherapy
Publication date: Available online 30 October 2019Source: Practical Radiation OncologyAuthor(s): David Stewart, Julius Ambat, Sian Wallis, Manasi Gurram, Rowena MartinAbstractPurposeCompare whole breast radiotherapy dose distributions with and without the use of breast cups to reposition the breast itself.Methods and MaterialsA fitted plastic breast cup repositions the breast on the anterior chest wall, reducing the lateral fall and ptosis of the breast. 18 Patients requiring breast cups were identified...
Thu Oct 31, 2019 12:39
Abstract Polymorphous sweat gland carcinoma (PSGC) is a rare and low‐grade malignant cutaneous neoplasm that presents as a slow‐growing, skin‐colored nodule in middle‐aged to older patients with no sex preference.1,2 Histologically, PSGC is a well‐circumscribed multinodular neoplasm composed of epithelioid cells arranged in an admixture of growth patterns within the same lesion, including trabecular, solid, pseudopapillary, and cylindromatous (adenoid cystic carcinoma‐like), though not all patterns...
Wed Oct 30, 2019 14:03
Related ArticlesLncRNA SNHG16 induces the SREBP2 to promote lipogenesis and enhance the progression of pancreatic cancer. Future Oncol. 2019 Oct 30;: Authors: Yu Y, Dong JT, He B, Zou YF, Li XS, Xi CH, Yu Y Abstract Aim: Blocking lipogenesis could significantly inhibit the progression of pancreatic cancer. Exploring the regulatory mechanisms of lipogenesis by lncRNA SNHG16 might be of great significance to control the development of pancreatic cancer....
Thu Oct 31, 2019 14:15
Related ArticlesRenal cell carcinoma in kidney transplant recipients: descriptive analysis and overview of a major German transplant center. Future Oncol. 2019 Oct 30;: Authors: Eggers H, Güler F, Ehlers U, Ivanyi P, Peters I, Grünwald V Abstract Aim: Elevated risk of malignancy-related death after renal transplantation is reported and renal malignancy was ranked as the third most frequent site of malignancy-related death. However, there is a lack of...
Thu Oct 31, 2019 14:15
Plasma miR-30a-5p as an early novel noninvasive diagnostic and prognostic biomarker for lung cancer.
Related ArticlesPlasma miR-30a-5p as an early novel noninvasive diagnostic and prognostic biomarker for lung cancer. Future Oncol. 2019 Oct 30;: Authors: Liang LB, Zhu WJ, Chen XM, Luo FM Abstract Aim: Circulation miRNAs have become increasingly appreciated in the diagnosis and prognosis of lung cancer. This study aims to identify and evaluate plasma miRNA-30a-5p as an early noninvasive biomarker for the diagnosis and prognosis of lung cancer. Pateints...
Thu Oct 31, 2019 14:15
Related ArticlesCarnosine increases efficiency of temozolomide and irradiation treatment of isocitrate dehydrogenase-wildtype glioblastoma cells in culture. Future Oncol. 2019 Oct 30;: Authors: Dietterle J, Oppermann H, Glasow A, Neumann K, Meixensberger J, Gaunitz F Abstract Aim: The naturally occurring dipeptide carnosine (CAR) has been considered for glioblastoma therapy. As CAR also protects against ionizing irradiation (IR), we investigated whether...
Thu Oct 31, 2019 14:15
Related ArticlesA Phase I/Ib trial of Ad-REIC in liver cancer: study protocol. Future Oncol. 2019 Oct 30;: Authors: Oyama A, Shiraha H, Uchida D, Iwamuro M, Kato H, Takaki A, Ikeda F, Onishi H, Yasunaka T, Takeuchi Y, Wada N, Iwasaki Y, Sakata M, Okada H, Kumon H Abstract This study will assess the safety and efficacy of the administration of adenoviral vector expressing the human-reduced expression in immortalized cells (Ad-REIC) to a liver tumor in...
Thu Oct 31, 2019 14:15
A 44 year old woman with hypertension and type 2 diabetes (treated with insulin) presented with recurrent 10-15 minute episodes of sweating, tachycardia with regular pulse (110-120 beats/minute),...
Thu Oct 31, 2019 12:01
The cautionary tale about Hans Eysenck is as much about hubris as hypothesis.1 Hypothesis based research is widely thought to be superior to the “fishing expeditions” of hypothesis-free research. But...
Thu Oct 31, 2019 11:55
This is pyoderma gangrenosum (fig 1) triggered by trauma from a tattoo.bmj;367/oct31_5/l5765/F1F1f1Fig 1The patient was a medically well 51 year old woman who developed painful studded pustules and...
Thu Oct 31, 2019 12:05
Social prescribingNew academy will develop best practiceThe Department of Health and Social Care announced a new charity, the National Academy for Social Prescribing, to benefit patients with long...
Thu Oct 31, 2019 11:36
Pierce and Bourton raise an important point on the need to emphasise the carbon impact of drugs in a way that is easily understandable and intuitive.12 Summarised, accessible information for...
Thu Oct 31, 2019 11:06
Cancers, Vol. 11, Pages 1692: Deconvolution of the Genomic and Epigenomic Interaction Landscape of Triple-Negative Breast Cancer Cancers doi: 10.3390/cancers11111692 Authors: Jiande Wu Tarun Karthik Kumar Mamidi Lu Zhang Chindo Hicks Triple-negative breast cancer (TNBC) is the most aggressive form of breast cancer. Emerging evidenced suggests that both genetics and epigenetic factors play a role in the pathogenesis of TNBC. However, oncogenic interactions and cooperation between...
Thu Oct 31, 2019 02:00
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