Abstract To determine the outcomes of using tragal cartilage in performing tympanoplasty. It was a prospective study of 57 patients with chronic suppurative otitis media. In all patients, pure tone audiometry was done pre-operatively. Tragal cartilage with attached perichondrium as graft material was used for ossicular chain reconstruction. In fifty out of the 57 participants, the outcome was intact ossicular chain. Of the 7 failures, 5 were recorded in the age group of 51–65 years,...
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Abstract Pleomorphic adenoma (PA) of minor salivary glands accounts for less than 3% of all head and neck tumors. It is a benign tumor. Palate is the most common site followed by upper lips. Tongue is an unusual site. We present a case report of a 35-year-old male patient who presented with a mass in the ventral surface of the tongue that was diagnosed as PA on FNAC and was treated by surgical excision. Patient was followed up and no recurrence was noted.
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There is a shortage of child psychiatrists in the United States. We identify trends in the level and distribution of child psychiatrists over the past decade (2007–2016).
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States’ religious vaccine exemption rates differ by personal belief exemption availability, may experience a replacement effect when personal belief exemptions are eliminated, and are increasing.
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Στις παρέες και τα οικογενειακά τραπέζια, τα τελευταία χρόνια, η κλιματική αλλαγή και η προστασία του περιβάλλοντος συζητούνται όλο και πιο έντονα – ίσως και λόγω της δημοσιότητας που έχει πάρει η δράση της 16χρονης Σουηδής ακτιβίστριας για το κλίμα Γκρέτα Τούνμπεργκ. Η κατανάλωση κρέατος, τα αεροπορικά ταξίδια που επιβαρύνουν την ατμόσφαιρα με ρύπους, η κυκλοφορία με συμβατικά αυτοκίνητα μεγάλου κυβισμού, απασχολούν έντονα. Λίγo – πολύ όλοι έχουμε την πρόθεση να κάνουμε κάτι καλό και ενώ ολοένα...
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Co‐immunoprecipitation studies show the conservation of the AMPK–ATG1 axis in basal autophagy. β‐actin was found as a novel interacting partner of AMPK, attributed to the alteration in macropinocytosis and phagocytosis in the absence of AMPK. Our findings suggest that AMPK provides links among pinocytosis, phagocytosis, and autophagy, and is requisite for basal autophagy in Dictyostelium. Abstract Autophagy is a degradation process, wherein long‐lived proteins, damaged organelles, and protein...
Sun Nov 03, 2019 18:20
The expression of circ_0080425 correlated with the diabetic nephropathy (DN) progression, and exerted positive effect on cell proliferation and fibrosis in mesangial cells. Circ_0080425 competitive binding to miR‐24‐3p could release FGF11 from miR‐24‐3p suppression, which subsequently promoted DN progression. In conclusion, we have reported a novel circ_0080425‐miR‐24‐3p‐FGF11 axis. Abstract Diabetic nephropathy (DN) is a severe end‐stage kidney disease developed from diabetes mellitus. The involvement...
Sun Nov 03, 2019 18:18
Pharmaceutics, Vol. 11, Pages 574: Gemcitabine Combination Nano Therapies for Pancreatic Cancer Pharmaceutics doi: 10.3390/pharmaceutics11110574 Authors: Kamalika Samanta Saini Setua Sonam Kumari Meena Jaggi Murali M. Yallapu Subhash C. Chauhan Pancreatic cancer is one of the deadliest causes of cancer-related death in the United States, with a 5-year overall survival rate of 6 to 8%. These statistics suggest that immediate medical attention is needed. Gemcitabine (GEM)...
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Pharmaceutics, Vol. 11, Pages 575: Synthesis, Characterization, and Three-Dimensional Structure Generation of Zinc Oxide-Based Nanomedicine for Biomedical Applications Pharmaceutics doi: 10.3390/pharmaceutics11110575 Authors: Su-Eon Jin Hyo-Eon Jin Zinc oxide (ZnO) nanoparticles have been studied as metal-based drugs that may be used for biomedical applications due to the fact of their biocompatibility. Their physicochemical properties, which depend on synthesis techniques involving...
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IJMS, Vol. 20, Pages 5481: Therapeutic Evaluation of Synthetic Peucedanocoumarin III in an Animal Model of Parkinson’s Disease International Journal of Molecular Sciences doi: 10.3390/ijms20215481 Authors: Sangwoo Ham Heejeong Kim Jin-Ha Yoon Hyojung Kim Bo Reum Song Jeong-Yun Choi Yun-Song Lee Seung-Mann Paek Han-Joo Maeng Yunjong Lee The motor and nonmotor symptoms of Parkinson’s disease (PD) correlate with the formation and propagation of aberrant...
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IJMS, Vol. 20, Pages 5480: Lack of Delta-Sarcoglycan (Sgcd) Results in Retinal Degeneration International Journal of Molecular Sciences doi: 10.3390/ijms20215480 Authors: Andric C. Perez-Ortiz Martha J. Peralta-Ildefonso Esmeralda Lira-Romero Ernesto Moya-Albor Jorge Brieva Israel Ramirez-Sanchez Carmen Clapp Alexandra Luna-Angulo Alvaro Rendon Elva Adan-Castro Gabriela Ramírez-Hernández Nundehui Díaz-Lezama Ramón M. Coral-Vázquez Francisco J. Estrada-Mena...
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IJMS, Vol. 20, Pages 5478: Emerging Highly Virulent Porcine Epidemic Diarrhea Virus: Molecular Mechanisms of Attenuation and Rational Design of Live Attenuated Vaccines International Journal of Molecular Sciences doi: 10.3390/ijms20215478 Authors: Yixuan Hou Qiuhong Wang The highly virulent porcine epidemic diarrhea virus (PEDV) emerged in China in 2010. It infects pigs of all ages, and causes severe diarrhea and high mortality rates in newborn pigs, leading to devastating economic...
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IJMS, Vol. 20, Pages 5477: Exploring the Regulatory Role of Circular RNAs in Neurodegenerative Disorders International Journal of Molecular Sciences doi: 10.3390/ijms20215477 Authors: Eleonora D’Ambra Davide Capauto Mariangela Morlando Circular RNAs (circRNAs) are a distinctive class of regulatory non-coding RNAs characterised by the presence of covalently closed ends. They are evolutionary conserved molecules, and although detected in different tissues, circRNAs resulted specifically...
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IJMS, Vol. 20, Pages 5476: Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix International Journal of Molecular Sciences doi: 10.3390/ijms20215476 Authors: Maxime Vermeulen Federico Del Vento Marc Kanbar Sébastien Pyr dit Ruys Didier Vertommen Jonathan Poels Christine Wyns Cryopreservation of immature testicular tissue (ITT) prior to chemo/radiotherapy is now ethically accepted and is currently the...
Sun Nov 03, 2019 02:00
Abstract Background The current study sought to investigate the impact of tumor size and total number of LN examined (TNLE) on the incidence of lymph node metastasis (LNM) among patients with duodenal neuroendocrine tumor (dNET). Methods Patients who underwent curative resection for dNETs between 1997‐2016 were identified from 8 high‐volume US centers. Risk factors associated with overall survival and LNM were identified and the optimal cut‐off of TNLE relative to LNM was determined. ...
Sun Nov 03, 2019 21:25
Abstract Background and Objectives Remifentanil infusion is used as an intraoperative anesthetic for thyroidectomy, but has been associated with acute opioid tolerance and hyperalgesia. A national shortage of remifentanil provided an opportunity to study postoperative pain in patients undergoing thyroidectomy. Methods Retrospective review of prospectively collected data from an outpatient surgery center. Primary analysis compared patients treated before and after remifentanil shortage....
Sun Nov 03, 2019 21:24
Abstract Background Despite the popularity of the U.S. News and World Report (USNWR) hospital rankings among the general public, the relationship between hospital rankings and actual patient outcomes for major cancers remains poorly investigated. Methods Medicare Inpatient Standard Analytic Files were queried from 2013–2015 to assess the relationship of postoperative outcomes and Medicare expenditures among patients undergoing surgery for colorectal, lung, esophageal, pancreatic, and liver...
Sun Nov 03, 2019 18:24
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01762C, PaperCaihui Rao, Zhichao Wang, zheyao li, Lu Chen, Chao Fu, Tingting Zhu, Xi Chen, Zhonghua Wang, Chuanxiang LiuA new efficient pyrdine-hydrazone-substituted naphthalimide receptor 4a-E has been synthesized as a selective colorimetric and fluorescent chemosensor for cyanide sensing in aqueous environments through a unique excited-state intramolecular proton transfer...The content of this RSS Feed (c) The Royal Society of Chemistry
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01358J, PaperYu-Chih Chen, Saswat Sahoo, Riley Brien, Seungwon Jung, Brock Humphries, Woncheol Lee, Yu-Heng Cheng, Zhixiong Zhang, Kathryn E. Luker, Max S Wicha, Gary Luker, Euisik YoonConsiderable evidence suggests breast cancer metastasis arises from cells undergoing epithelial-to-mesenchymal-transition (EMT) and cancer stem-like cells (CSCs). Using a microfluidic device that enriches migratory breast cancer cells with enhanced capacity...The...
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The identification of discriminative features from information-rich data with the goal of clinical diagnosis is crucial in the field of biomedical science. In this context, many machine-learning techniques have been widely applied and achieved remarkable results. However, disease, especially cancer, is often caused by a group of features with complex interactions. Unlike traditional feature selection methods, which only focused on finding single discriminative features, a multilayer feature subset...
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Aim. To determine whether the area of the foveal avascular zone (FAZ), as a morphological indicator of the microcirculation of the perifoveal capillary network, changes in the carbohydrate metabolism disorders during pregnancy (the gestational age of patients with gestational diabetes mellitus (GDM) and preexisting diabetes (PexD)). Methods. Ten normal individuals and 41 eyes of 41 patients, 28 with GDM and 13 with PexD, were studied. A 3 × 3 mm area of the FAZ of the superficial capillary plexus...
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Τις ξεχωριστές ανάγκες, από τη διάγνωση μέχρι και μετά το τέλος της θεραπείας, και τα κενά στη φροντίδα της ειδικής ηλικιακής ομάδας των Εφήβων και Νεαρών Ενηλίκων (ΕΝΕ) ογκολογικών ασθενών, αναδεικνύει μιλώντας στο ΑΠΕ-ΜΠΕ η Μαρίνα Σερβιτζόγλου, διευθύντρια ΕΣΥ Ογκολογικό Τμήμα Νοσοκομείο Παίδων «Π&Α Κυριακού», γενική γραμματέας της Ελληνικής Εταιρείας Παιδιατρικής Αιματολογίας Ογκολογίας. Τονίζει ότι παρόλο που οι έφηβοι και νεαροί ενήλικες (15 έως 19 ετών) με καρκίνο αντιπροσωπεύουν το 7%...
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Γρίπη, πνευμονιόκοκκος, έρπητας ζωστήρας: Τρεις λοιμώδεις νόσοι που πλήττουν τον ενήλικο πληθυσμό, αυξάνοντας τις νοσηλείες, αλλά και τους θανάτους. Κι όμως, οι σοβαρές αυτές ασθένειες μπορούν να προληφθούν μέσω του εμβολιασμού. Αυτό είναι το μήνυμα της ενημερωτικής εκστρατείας, που πραγματοποιείται για δεύτερη συνεχόμενη χρονιά από το Διαδημοτικό Δίκτυο Υγιών Πόλεων, και στο οποίο παίρνουν μέρος 20 δήμοι σε όλη τη χώρα. Στην εκστρατεία, με σύνθημα «Εμβολιάζομαι. Ζω χωρίς το φόβο», παίρνουν μέρος...
Sun Nov 03, 2019 23:24
Antibodies, Vol. 8, Pages 52: Immunoglobulin for Treating Bacterial Infections: One More Mechanism…Antibodies, Vol. 8, Pages 52: Immunoglobulin for Treating Bacterial Infections: One More Mechanism of ActionAntibodies, Vol. 8, Pages 52: Immunoglobulin for Treating Bacterial Infections: One More Mechanism of Action Antibodies doi: 10.3390/antib8040052 Authors: Sawa Kinoshita Inoue Ohara Moriyama The mechanisms underlying the effects of immunoglobulins on bacterial infections are thought to involve...
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Ποια είναι, λοιπόν, τα «σημάδια» που τη φανερώνουν και σίγουρα αξίζει να γνωρίζουμε; Τι μπορούμε…
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Είναι αρκετά δύσκολο για μια γυναίκα να υπολογίσει κάθε μήνα πότε θα έρθει η περίοδός…
Sun Nov 03, 2019 20:00
Ο καταρράκτης, το γλαύκωμα και η εκφύλιση της ωχράς κηλίδας είναι τρεις πολύ συχνές οφθαλμολογικές…
Sun Nov 03, 2019 13:45
Ο καθηγητής Χαράλαμπος Π. Συμεωνίδης σπούδασε κλασική φιλολογία και γλωσσολογία στο Αριστοτέλειο Πανεπιστήμιο Θεσσαλονίκης (1952-1956). Έκανε μεταπτυχιακές σπουδές ως υπότροφος της Alexander von Humboldt-Stiftung και της Deutsche Forschungsgemeinschaft στα Πανεπιστήμια Βόννης, Κολωνίας και Μονάχου (1965-1970) στις ειδικεύσεις γενική γλωσσολογία, ιστορικοσυγκριτική γλωσσολογία και βαλκανική γλωσσολογία. Υπηρέτησε στο Πανεπιστήμιο Θεσσαλονίκης από το 1960 και εξής πάνω από 40 χρόνια.
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Το Τμήμα Ελληνικής Φιλολογίας του Δημοκριτείου Πανεπιστημίου Θράκης και ειδικότερα το Εργαστήριο Έρευνας για τη Νεοελληνική και Συγκριτική Φιλολογία διοργανώνει Συνέδριο με θέμα «Αυτοβιογραφικός Λόγος: από τα κείμενα προς την έρευνα και τη θεωρία».
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Η επίκουρη καθηγήτρια Συγκριτικής Φιλολογίας του Πανεπιστημίου Πατρών κ. Άννα Κατσιγιάννη θα μιλήσει την Τρίτη 5 Νοεμβρίου 2019, ώρα 19:00, με θέμα: H μυθοποίηση της Ρωσίας και ο συγχρονισμός των τεχνών στο «Αμούρ-Αμούρ» του Ανδρέα Εμπειρίκου. Η εκδήλωση θα γίνει στο στο Σπουδαστήριο Μ.Ν.Ε.Σ., αίθουσα 208 (2ος όροφος Νέου Κτιρίου Φιλοσοφικής Σχολής, ΑΠΘ).
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Το Πανεπιστήμιο Ιωαννίνων - Σχολή Επιστημών Αγωγής, Παιδαγωγικό Τμήμα Νηπιαγωγών και η Ένωση Συντακτών Ημερησίων Εφημερίδων Πελοποννήσου, Ηπείρου, Νήσων (μέλος της Π.Ο.Ε.Σ.Υ.) οργανώνουν για το ακαδημαϊκό έτος 2019-2020 τα «Μικρά Σεμινάρια» Ελληνικής Γλώσσας, Πολιτισμού και Μέσων Ενημέρωσης. Πρόκειται για ένα πολύ σημαντικό πρόγραμμα επιμόρφωσης σε θέματα γλώσσας και επικοινωνίας, το οποίο ξεκίνησε το 2013 στο Παιδαγωγικό Τμήμα Νηπιαγωγών (με τον τίτλο τότε «Μικρά Σεμινάρια» Γραμματικής και Ορθογραφίας)...
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