Antibiotics, Vol. 8, Pages 132: Reduced Incidence of Carbapenem-Resistant Klebsiella pneumoniae Infections in Cardiac Surgery Patients after Implementation of an Antimicrobial Stewardship Project Antibiotics doi: 10.3390/antibiotics8030132 Authors: Giacobbe Salsano Puente Campanini Mariscalco Marchese Viscoli Santini Infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) are associated with increased mortality in cardiac surgery patients. In...
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Arts, Vol. 8, Pages 109: From the Memory Books of Josely Carvalho Arts doi: 10.3390/arts8030109 Authors: Erina Duganne In this interview, Brazilian-born multi-media artist Josely Carvalho (b. 1942) reflects back on her art making practice in the 1980s. Among the subjects that she addresses are her bi-nationalism, her use of the silkscreen process, and her association with the 1984 activist campaign Artists Call Against U.S. Intervention in Central America. She also speaks about working...
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Atmosphere, Vol. 10, Pages 504: Surface Heat Fluxes over the Northern Arabian Gulf and the Northern Red Sea: Evaluation of ECMWF-ERA5 and NASA-MERRA2 Reanalyses Atmosphere doi: 10.3390/atmos10090504 Authors: Fahad Al Senafi Ayal Anis Viviane Menezes The air–sea heat fluxes in marginal seas and under extreme weather conditions constitute an essential source for energy transport and mixing dynamics. To reproduce these effects in numerical models, we need a better understanding...
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Bioengineering, Vol. 6, Pages 76: Gelatin-Methacryloyl (GelMA) Formulated with Human Platelet Lysate Supports Mesenchymal Stem Cell Proliferation and Differentiation and Enhances the Hydrogel’s Mechanical Properties Bioengineering doi: 10.3390/bioengineering6030076 Authors: Marline Kirsch Luise Birnstein Iliyana Pepelanova Wiebke Handke Jessica Rach Axel Seltsam Thomas Scheper Antonina Lavrentieva Three-dimensional (3D) cell culture is a major focus of current research,...
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Biology, Vol. 8, Pages 62: Uncovering Olive Biodiversity through Analysis of Floral and Fruiting Biology and Assessment of Genetic Diversity of 120 Italian Cultivars with Minor or Marginal Diffusion Biology doi: 10.3390/biology8030062 Authors: Lombardo Fila Lombardo Epifani III Godino Salimonti Zelasco The primary impetus behind this research was to provide a boost to the characterization of the Italian olive biodiversity by acquiring reliable and homogeneous...
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Biomedicines, Vol. 7, Pages 65: A Brief Review about the Role of Nanomaterials, Mineral-Organic Nanoparticles, and Extra-Bone Calcification in Promoting Carcinogenesis and Tumor Progression Biomedicines doi: 10.3390/biomedicines7030065 Authors: Marina Senchukova People come in contact with a huge number of nanoparticles (NPs) throughout their lives, which can be of both natural and anthropogenic origin and are capable of entering the body through swallowing, skin penetration, or inhalation....
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Biomolecules, Vol. 9, Pages 424: Comparative Analysis of Panax ginseng Berries from Seven Cultivars Using UPLC-QTOF/MS and NMR-Based Metabolic Profiling Biomolecules doi: 10.3390/biom9090424 Authors: Yoon Choi Kim Oh Kim Kim Baek Kim Lee The commercial use of Panax ginseng berries is increasing as P. ginseng berries are known to contain large amounts of ginsenosides, and many pharmacological activities have been reported for the various ginsenosides....
Biomolecules, Vol. 9, Pages 423: Lignin and Cellulose Blends as Pharmaceutical Excipient for Tablet Manufacturing via Direct Compression Biomolecules doi: 10.3390/biom9090423 Authors: Domínguez-Robles Stewart Rendl González Donnelly Larrañeta Extensive efforts are being made to find alternative uses for lignin (LIG). In the present work the use of this biopolymer as excipient to prepare tablets was studied. For this purpose, LIG was combined with microcrystalline...
Biomolecules, Vol. 9, Pages 422: The Common Partner of Several Methyltransferases TRMT112 Regulates the Expression of N6AMT1 Isoforms in Mammalian Cells Biomolecules doi: 10.3390/biom9090422 Authors: Leetsi Õunap Abroi Kurg Methylation is a widespread modification occurring in DNA, RNA and proteins. The N6AMT1 (HEMK2) protein has DNA N6-methyladenine as well as the protein glutamine and histone lysine methyltransferase activities. The human genome encodes two different isoforms...
Biomolecules, Vol. 9, Pages 421: Tumor Uptake of Triazine Dendrimers Decorated with Four, Sixteen, and Sixty-Four PSMA-Targeted Ligands: Passive versus Active Tumor Targeting Biomolecules doi: 10.3390/biom9090421 Authors: Jongdoo Lim Bing Guan Kien Nham Guiyang Hao Xiankai Sun Eric E. Simanek Various glutamate urea ligands have displayed high affinities to prostate specific membrane antigen (PSMA), which is highly overexpressed in prostate and other cancer sites. The multivalent...
Biomolecules, Vol. 9, Pages 420: Roles of Small-Molecule Compounds in Plant Adventitious Root Development Biomolecules doi: 10.3390/biom9090420 Authors: Yuzheng Deng Chunlei Wang Ni Wang Lijuan Wei Weifang Li Yandong Yao Weibiao Liao Adventitious root (AR) is a kind of later root, which derives from stems and leaf petioles of plants. Many different kinds of small signaling molecules can transmit information between cells of multicellular organisms. It has been found...
Biomolecules, Vol. 9, Pages 419: Mycogenic Selenium Nanoparticles as Potential New Generation Broad Spectrum Antifungal Molecules Biomolecules doi: 10.3390/biom9090419 Authors: Shreya M. Joshi Savitha De Britto Sudisha Jogaiah Shin-ichi Ito The current challenges of sustainable agricultural development augmented by global climate change have led to the exploration of new technologies like nanotechnology, which has potential in providing novel and improved solutions. Nanotools...
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Biosensors, Vol. 9, Pages 103: Silk Fibroin-Sheathed Conducting Polymer Wires as Organic Connectors for Biosensors Biosensors doi: 10.3390/bios9030103 Authors: Yanke Jiang Meng Xu Vamsi K Yadavalli Conductive polymers, owing to their tunable mechanical and electrochemical properties, are viable candidates to replace metallic components for the development of biosensors and bioelectronics. However, conducting fibers/wires fabricated from these intrinsically conductive and mechanically...
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Brain Sciences, Vol. 9, Pages 218: New Design of the Electrophoretic Part of CLARITY Technology for Confocal Light Microscopy of Rat and Human Brains Brain Sciences doi: 10.3390/brainsci9090218 Authors: Petr Zach Jana Mrzílková Jan Pala Libor Uttl Viera Kútna Vladimír Musil Blanka Sommerová Petr Tůma Background: CLARITY is a method of rendering postmortem brain tissue transparent using acrylamide-based hydrogels so that this tissue could be further used for immunohistochemistry,...
Brain Sciences, Vol. 9, Pages 217: A Deep Learning approach for Diagnosis of Mild Cognitive Impairment Based on MRI Images Brain Sciences doi: 10.3390/brainsci9090217 Authors: Gorji Kaabouch Mild cognitive impairment (MCI) is an intermediary stage condition between healthy people and Alzheimer’s disease (AD) patients and other dementias. AD is a progressive and irreversible neurodegenerative disorder, which is a significant threat to people, age 65 and older. Although...
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Cancers, Vol. 11, Pages 1268: Novel Human Bispecific Aptamer–Antibody Conjugates for Efficient Cancer Cell Killing Cancers doi: 10.3390/cancers11091268 Authors: Margherita Passariello Simona Camorani Cinzia Vetrei Laura Cerchia Claudia De Lorenzo Monoclonal antibodies have been approved by the Food and Drug Administration for the treatment of various human cancers. More recently, oligonucleotide aptamers have risen increasing attention for cancer therapy thanks to their low...
Cancers, Vol. 11, Pages 1267: Glycolipids Recognized by A2B5 Antibody Promote Proliferation, Migration, and Clonogenicity in Glioblastoma Cells Cancers doi: 10.3390/cancers11091267 Authors: Baeza-Kallee Bergès Soubéran Colin Denicolaï Appay Tchoghandjian Figarella-Branger A2B5+ cells isolated from human glioblastomas exhibit cancer stem cell properties. The A2B5 epitope belongs to the sialoganglioside family and is synthetized by the ST8 alpha-N-acetyl-neuraminidase...
Cancers, Vol. 11, Pages 1266: Glycan-Modified Melanoma-Derived Apoptotic Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination Cancers doi: 10.3390/cancers11091266 Authors: Horrevorts Stolk Ven Hulst Hof Duinkerken Heineke Ma Dusoswa Nieuwland Garcia-Vallejo Loosdrecht de Gruijl Vliet van Kooyk Tumors that lack T cell infiltration are less likely to respond to immune checkpoint inhibition and could benefit from cancer...
Cancers, Vol. 11, Pages 1265: Current Status of Gene Therapy in Hepatocellular Carcinoma Cancers doi: 10.3390/cancers11091265 Authors: Saranya Chidambaranathan Reghupaty Devanand Sarkar Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading cause of cancer related deaths world-wide. Liver transplantation, surgical resection, trans-arterial chemoembolization, and radio frequency ablation are effective strategies to treat early stage HCC. Unfortunately,...
Cancers, Vol. 11, Pages 1263: Health-Related Quality of Life during Chemoradiation in Locally Advanced Rectal Cancer: Impacts and Ethnic Disparities Cancers doi: 10.3390/cancers11091263 Authors: Stephanie Hui-Su Lim Emilia Ip Weng Ng Wei Chua Ray Asghari Aflah Roohullah Joseph Descallar Christopher Henderson Kevin Spring Paul de Souza Madeleine T. King Aims: There is limited data on health-related quality of life (HRQoL) in locally advanced rectal cancer....
Cancers, Vol. 11, Pages 1264: Human Cachexia Induces Changes in Mitochondria, Autophagy and Apoptosis in the Skeletal Muscle Cancers doi: 10.3390/cancers11091264 Authors: Gabriela S. de Castro Estefania Simoes Joanna D.C.C. Lima Milene Ortiz-Silva William T. Festuccia Flávio Tokeshi Paulo S. Alcântara José P. Otoch Dario Coletti Marilia Seelaender Cachexia is a wasting syndrome characterized by the continuous loss of skeletal muscle mass due to imbalance between...
Cancers, Vol. 11, Pages 1261: Targeting of CD133+ Cancer Stem Cells by Mesenchymal Stem Cell Expressing TRAIL Reveals a Prospective Role of Apoptotic Gene Regulation in Non-Small Cell Lung Cancer Cancers doi: 10.3390/cancers11091261 Authors: Kamal Shaik Fakiruddin Moon Nian Lim Norshariza Nordin Rozita Rosli Zubaidah Zakaria Syahril Abdullah Mesenchymal stem cells (MSCs) are emerging as vehicles for anti-tumor cytotherapy; however, investigation on its efficacy to target...
Cancers, Vol. 11, Pages 1262: BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors Cancers doi: 10.3390/cancers11091262 Authors: Karisa C. Schreck Stuart A. Grossman Christine A. Pratilas BRAF mutations have been identified as targetable, oncogenic mutations in many cancers. Given the paucity of treatments for primary brain tumors and the poor prognosis associated with high-grade gliomas, BRAF mutations in glioma are of considerable interest. In this...
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Cells, Vol. 8, Pages 999: Hyperglycemia-Induced Aberrant Cell Proliferation; A Metabolic Challenge Mediated by Protein O-GlcNAc Modification Cells doi: 10.3390/cells8090999 Authors: Nagy Fisi Frank Kátai Nagy Miseta Chronic hyperglycemia has been associated with an increased prevalence of pathological conditions including cardiovascular disease, cancer, or various disorders of the immune system. In some cases, these associations may be traced back to a common underlying...
Cells, Vol. 8, Pages 998: Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein Cells doi: 10.3390/cells8090998 Authors: Bang-Christensen Pedersen Pereira Clausen Løppke Sand Ahrens Jørgensen Lim Goksøyr Choudhary Gustavsson Dagil Daugaard Sander Torp Søgaard Theander Østrup Lassen Hamerlik Salanti Agerbæk Diffuse gliomas are the most common primary malignant...
Cells, Vol. 8, Pages 996: Glutamate at the Vertebrate Neuromuscular Junction: From Modulation to Neurotransmission Cells doi: 10.3390/cells8090996 Authors: Colombo Francolini Although acetylcholine is the major neurotransmitter operating at the skeletal neuromuscular junction of many invertebrates and of vertebrates, glutamate participates in modulating cholinergic transmission and plastic changes in the last. Presynaptic terminals of neuromuscular junctions contain and release...
Cells, Vol. 8, Pages 997: Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation Cells doi: 10.3390/cells8090997 Authors: Meurer Wimmer Leur Weiskirchen Injury of the liver involves a wound healing partial reaction governed by hepatic stellate cells and portal fibroblasts. Individual members of the transforming growth factor-β (TGF-β) superfamily including TGF-β itself and bone morphogenetic proteins (BMP) exert diverse...
Cells, Vol. 8, Pages 994: Tracing IgE-Producing Cells in Allergic Patients Cells doi: 10.3390/cells8090994 Authors: Julia Eckl-Dorna Sergio Villazala-Merino Nicholas James Campion Maria Byazrova Alexander Filatov Dmitry Kudlay Antonina Karsonova Ksenja Riabova Musa Khaitov Alexander Karaulov Verena Niederberger-Leppin Rudolf Valenta Immunoglobulin E (IgE) is the key immunoglobulin in the pathogenesis of IgE associated allergic diseases affecting 30% of...
Cells, Vol. 8, Pages 993: Differential Effects of Extracellular Vesicles of Lineage-Specific Human Pluripotent Stem Cells on the Cellular Behaviors of Isogenic Cortical Spheroids Cells doi: 10.3390/cells8090993 Authors: Mark Marzano Julie Bejoy Mujeeb R. Cheerathodi Li Sun Sara B. York Jing Zhao Takahisa Kanekiyo Guojun Bu David G. Meckes Yan Li Extracellular vesicles (EVs) contribute to a variety of signaling processes and the overall physiological and pathological...
Cells, Vol. 8, Pages 995: The Differences in the Proteome Profile of Cannabidiol-Treated Skin Fibroblasts following UVA or UVB Irradiation in 2D and 3D Cell Cultures Cells doi: 10.3390/cells8090995 Authors: Agnieszka Gęgotek Sinemyiz Atalay Pedro Domingues Elżbieta Skrzydlewska Cannabidiol (CBD), as the only phytocannabinoid that has no psychoactive effect, has both antioxidant and anti-inflammatory effects, and thus might be suggested as a cytoprotective compound against UV-induced...
Cells, Vol. 8, Pages 992: Dynamic Interactions between Autophagosomes and Lipid Droplets in Chlamydomonas reinhardtii Cells doi: 10.3390/cells8090992 Authors: Quynh-Giao Tran Hyang Ran Yoon Kichul Cho Seon-Jin Lee José L. Crespo Rishiram Ramanan Hee-Sik Kim Autophagy is a highly conserved catabolic process in eukaryotic cells by which waste cellular components are recycled to maintain growth in both favorable and stress conditions. Autophagy has been linked to lipid...
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Diagnostics, Vol. 9, Pages 107: Liver Fibrosis Assessment with Diffusion-Weighted Imaging: Value of Liver Apparent Diffusion Coefficient Normalization Using the Spleen as a Reference Organ Diagnostics doi: 10.3390/diagnostics9030107 Authors: Shin Song Hwang Hwang Kim Moon Liver fibrosis staging is of great clinical importance because it is used to assess the severity of the underlying chronic liver disease. Among various imaging-based methods, apparent diffusion...
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Foods, Vol. 8, Pages 370: Comprehensive Nutrition Review of Grain-Based Muesli Bars in Australia: An Audit of Supermarket Products Foods doi: 10.3390/foods8090370 Authors: Felicity Curtain Sara Grafenauer Muesli bars are consumed by 16% of children, and 7.5% of adults, and are classified as discretionary in Australian Dietary Guidelines, containing “higher fat and added sugars” compared with core food choices. This study aimed to provide a nutritional overview...
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Heritage, Vol. 2, Pages 2480-2494: Multi-Scale Investigation of Body-Glaze Interface in Ancient Ceramics Heritage doi: 10.3390/heritage2030152 Authors: Marie Godet Gauthier Roisine Emmie Beauvoit Daniel Caurant Odile Majérus Nicolas Menguy Olivier Dargaud Anne Bouquillon Laurent Cormier Bernard Palissy is a French Renaissance ceramist renowned for his masterpieces called Rustiques Figulines on which dozens of glazes of different chemistries (and thus firing behaviors)...
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Humanities, Vol. 8, Pages 145: Classifications of Macca Oromoo Girls’ Nuptial Songs (Sirba Cidhaa) Humanities doi: 10.3390/h8030145 Authors: Bidu Girls’ nuptial songs of the Oromoo of Horn of Africa are powerful folksong genres, but are rarely practiced today. Ethnographic data were collected and analyzed contextually, structurally, functionally, and semantically from multidisciplinary approaches: folklore, ethnomusicology, anthropology, sociology, literature, linguistic,...
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IJERPH, Vol. 16, Pages 3148: Association of Depression and Excessive Daytime Sleepiness among Sleep-Deprived College Freshmen in Northern Taiwan International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173148 Authors: Meng-Ting Tsou Betty Chia-Chen Chang Background. The aim of this study was to investigate depression and other determinants (sleep-deprived behaviors such as hours spent sleeping, watching television, and on the computer) and their association...
IJERPH, Vol. 16, Pages 3147: Risk of Seizures in Patients with Organophosphate Poisoning: A Nationwide Population-Based Study International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173147 Authors: Chieh-Sen Chuang Kai-Wei Yang Chia-Ming Yen Cheng-Li Lin Chia-Hung Kao Objective: Previous research has demonstrated that patients with a history of organophosphate poisoning tend to have a higher risk of neurological disorder. However, research on...
IJERPH, Vol. 16, Pages 3144: An Intervention to Improve Uptake of Referrals for Children with Ear Disease or Hearing Loss in Thyolo District, Malawi: Acceptability and Feasibility International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173144 Authors: Baum Mulwafu Phiri Polack Bright (1) Introduction: Poor uptake of referral for ear and hearing services in Malawi has been demonstrated in previous research. A multi-component educational...
IJERPH, Vol. 16, Pages 3145: Methods of Measuring and Processing Signals during Tests of the Exposure of a Motorcycle Driver to Vibration and Noise International Journal of Environmental Research and Public Health doi: 10.3390/ijerph16173145 Authors: Tomasz Figlus Piotr Szafraniec Tomáš Skrúcaný The paper presents a new method of measuring a motorcycle driver’s exposure to vibration and noise. This method uses the simultaneous measurement of vibration and noise at the...
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