Superior laryngeal nerve block for neurogenic cough: A case series.Related ArticlesSuperior laryngeal nerve block for neurogenic cough: A case series. Laryngoscope Investig Otolaryngol. 2019 Aug;4(4):410-413 Authors: Dhillon VK Abstract Objectives: To demonstrate that an in-office superior laryngeal nerve (SLN) block with lidocaine and steroids is an effective alternative to neuromodulators for patients with neurogenic cough. Study Design: Retrospective stu- Qualitative investigation of the speech-language therapy experiences of individuals who covertly stutter.Related ArticlesQualitative investigation of the speech-language therapy experiences of individuals who covertly stutter. J Fluency Disord. 2019 Aug 20;:105713 Authors: Douglass JE, Constantino C, Alvarado J, Verrastro K, Smith K Abstract PURPOSE: Individuals who covertly stutter have a unique experience of stuttering that involves concealing the core behaviors of stuttering (e.g., repetitions, prolo
- Visual supports at home and in the community for individuals with autism spectrum disorders: A scoping review.Related ArticlesVisual supports at home and in the community for individuals with autism spectrum disorders: A scoping review. Autism. 2019 Aug 26;:1362361319871756 Authors: Rutherford M, Baxter J, Grayson Z, Johnston L, O'Hare A Abstract Visual supports are recommended in autism spectrum disorder clinical guidelines. They can reduce anxiety, increase predictability, support communication and improve
- Measurement of child-directed speech: A survey of clinical practice.Related ArticlesMeasurement of child-directed speech: A survey of clinical practice. Int J Speech Lang Pathol. 2019 Aug 26;:1-15 Authors: Newbury J, Sutherland D Abstract Purpose: Clear correlations exist between the quality and quantity of child-directed speech (CDS) and children's language development. Interventions for children with poor language skills involve manipulation of the quality and/or q
- Dynamics of Dynamin-Related Protein 1 in Alzheimer's Disease and Other Neurodegenerative Diseases.Related ArticlesDynamics of Dynamin-Related Protein 1 in Alzheimer's Disease and Other Neurodegenerative Diseases. Cells. 2019 Aug 23;8(9): Authors: Oliver D, Reddy PH Abstract The purpose of this article is to highlight the role of dynamin-related protein 1 (Drp1) in abnormal mitochondrial dynamics, mitochondrial fragmentation, autophagy/mitophagy, and neuronal damage in Alzheimer's disease (AD) and
- Functional skills and caregiver assistance of Brazilian children and adolescents with Down syndrome.Related ArticlesFunctional skills and caregiver assistance of Brazilian children and adolescents with Down syndrome. NeuroRehabilitation. 2019 Aug 19;: Authors: Moriyama CH, Mustacchi Z, Pires S, Massetti T, da Silva T, Herrero D, da Abreu L, Monteiro C, Leone C Abstract BACKGROUND: Research into the evolution of the functional performance of children and adolescents with DS enables parents and profe
- Assessment of conversational pragmatics: A screening tool for pragmatic language impairment in a control population of children aged 6-12 years.Related ArticlesAssessment of conversational pragmatics: A screening tool for pragmatic language impairment in a control population of children aged 6-12 years. Arch Pediatr. 2019 May;26(4):214-219 Authors: Gentilleau-Lambin P, Nicli J, Richard AF, Macchi L, Barbeau C, Nguyen S, Medjkane F, Lemaître MP Abstract Pragmatics can be defined as the way in which language is used to communicate in a
- Capitalizing on technology for developing communication skills in autism spectrum disorder: a single case study.Related ArticlesCapitalizing on technology for developing communication skills in autism spectrum disorder: a single case study. Disabil Rehabil Assist Technol. 2019 01;14(1):75-81 Authors: Mohan V, Kunnath SK, Philip VS, Mohan LS, Thampi N Abstract PURPOSE: In this case study, we discuss the application of a patient-centred clinical approach that led to the use of an assisted communication platfor
- An optimized retinoic acid-inducible gene I agonist M8 induces immunogenic cell death markers in human cancer cells and dendritic cell activationAbstract RIG-I is a cytosolic RNA sensor that recognizes short 5′ triphosphate RNA, commonly generated during virus infection. Upon activation, RIG-I initiates antiviral immunity, and in some circumstances, induces cell death. Because of this dual capacity, RIG-I has emerged as a promising target for cancer immunotherapy. Previously, a sequence-optimized RIG-I agonist (termed M8) was generated and shown to stimulate a robust im
- Which is the best choice after tooth extraction, immediate implant placement or delayed placement with alveolar ridge preservation? A systematic review and meta-analysisPublication date: Available online 27 August 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): João Vitor dos Santos Canellas, Paulo Jose D’Albuquerque Medeiros, Carlos Marcelo da Silva Figueredo, Ricardo Guimaraes Fischer, Fabio Gamboa RittoSummaryA comprehensive literature search on implant placement protocols after tooth extraction (immediate, early, delayed, or later) was performed up to 2018. The screening process selected only r
- Inflammasomes: Threat-Assessment Organelles of the Innate Immune SystemProteins that drive inflammasome activities are responsive to diverse threats to the host, including infection, tissue damage, or both. Upon threat identification, specific regulatory proteins seed the assembly of inflammasomes, which drive inflammatory responses that influence local and systemic immunity. Evavold and Kagan discuss mechanisms and consequences of inflammasome activities.
- Effects of bilingual language experience on basal ganglia computations: A dynamic causal modeling test of the conditional routing modelPublication date: October 2019Source: Brain and Language, Volume 197Author(s): Brianna L. Yamasaki, Andrea Stocco, Allison S. Liu, Chantel S. PratAbstractBilingual language control is characterized by the ability to select from amongst competing representations based on the current language in use. According to the Conditional Routing Model (CRM), this feat is underpinned by basal-ganglia signal-routing mechanisms, and may have implications for c
- Concussion assessment tools – a possible measure of sleepiness?Publication date: Available online 27 August 2019Source: Sleep MedicineAuthor(s): David Stevens, Louis Holtzhausen, Sarah Appleton, Robert Adams
- Stress overload‐induced periodontal remodelling coupled with changes in high mobility group protein B1 during tooth movement: an in‐vivo studyHigh mobility group protein B1 (HMGB1), a bone‐active cytokine and an osteocyte alarmin, might have dual functions in bone metabolism that could benefit bone formation and accelerate osteoclastogenic activity. High mobility group protein B1 was recently shown to be involved in tooth movement. Here, we investigated the expression of HMGB1, which remains poorly elucidated, under stress overload‐induced periodontal remodelling conditions in vivo. Th
- Safety of resection margins in CAD/CAM-guided primarily reconstructed oral squamous cell carcinoma—a retrospective case seriesAbstract Objectives After resection of malignancies of the jaws, CAD/CAM procedures have become standard for primary bony reconstruction. Even so, these techniques may limit surgical resection safety. Therefore, the aim of the study was to examine osseous as well as soft tissue resection margins after CAD/CAM-guided tumor resections and reconstructions.
- Safety of resection margins in CAD/CAM-guided primarily reconstructed oral squamous cell carcinoma—a retrospective case seriesAbstract Objectives After resection of malignancies of the jaws, CAD/CAM procedures have become standard for primary bony reconstruction. Even so, these techniques may limit surgical resection safety. Therefore, the aim of the study was to examine osseous as well as soft tissue resection margins after CAD/CAM-guided tumor resections and reconstructions.
- The projection of anorectal afferents to cortex of the rat: Comparison of two methods of cortical mappingAbstract Background The rat has served usefully as a model for fecal incontinence and exploration of the mechanism of action of sacral neuromodulation. However, there is a gap in knowledge concerning representation(s) on the primary sensory cortex of this anatomical region. Methods Multi‐electrode array (32 channels) and intrinsic optical signal (IOS) processing were used to map cortical activation sites following anorectal electrical s
- Advanced age adversely affects chronic rhinosinusitis surgical outcomesBackground Patient‐specific and disease‐specific factors shape the course of chronic rhinosinusitis (CRS) and its response to treatment, with optimal management involving interventions tailored to these factors. Recent evidence suggests CRS inflammatory signatures depend on age. The objective of this study was to determine whether age also influences quality‐of‐life (QOL) and postoperative outcomes. Methods Retrospective analysis of prospe
- Novel Frameshift Mutations in DSPP Cause Dentin Dysplasia Type IIAbstract The current classification system of hereditary dentin defects was proposed in 1973 (Shields et al., 1973) based on clinical and radiographic information without knowledge of the underlying molecular pathophysiology: three types of dentinogenesis imperfecta (DGI‐I, DGI‐II, and DGI‐III) and 2 types of dentin dysplasia (DD‐I and DD‐II). This article is protected by copyright. All rights reserved.
- Psychological Services for food allergy: the unmet need for patients and families in the UKAbstract Research over the past twenty years has demonstrated the significant impact food allergy can have on quality of life and mental health of patients and their families, yet there is a paucity of psychological services to support families in coping with this condition. This paper provides a short overview of the psychological impact of food allergy, followed by a discussion of the use of paediatric psychological services for long‐term cond
- Clinical Analysis of Denture Impaction in the Esophagus of AdultsAbstract Denture impacted in the esophagus of adults has been a complex foreign body for otolaryngologists. We reviewed clinical characteristics, diagnosis, and treatment of these patients and evaluated computed tomography (CT) scans to identify a better method of dealing with such tricky situations. Twenty-nine patients who underwent rigid esophagoscopy were included in this retrospective study conducted at the University hosp
- Clinical Analysis of Denture Impaction in the Esophagus of AdultsAbstract Denture impacted in the esophagus of adults has been a complex foreign body for otolaryngologists. We reviewed clinical characteristics, diagnosis, and treatment of these patients and evaluated computed tomography (CT) scans to identify a better method of dealing with such tricky situations. Twenty-nine patients who underwent rigid esophagoscopy were included in this retrospective study conducted at the University hosp
- Rekonstruktion der unteren Extremität im Alter – ein interdisziplinärer AnsatzZusammenfassung Verletzungen der unteren Extremität bei multimorbiden und geriatrischen Patienten stellen eine zunehmende Herausforderung dar, wobei ein interdisziplinäres Setting für den Erfolg der Therapie erforderlich ist. Ziel der interdisziplinären Therapie ist die funktionelle Extremitätenrekonstruktion durch knöcherne Rekonstruktion, Revaskularisation und Defektdeckung mit Erhalt der Mobilität sowie der möglichst schnell
- Verletzungen der Halswirbelsäule im AlterZusammenfassung Untersuchungen zeigen, dass die Anzahl der Verletzungen der Halswirbelsäule (HWS) im Alter zunimmt. Eine zeitnahe klinische Untersuchung und adäquate Diagnostik sind notwendig, um eine regelrechte Therapie einzuleiten. Daher wird eine Computertomographie empfohlen, um Verletzungen der HWS auszuschließen. Bei Fragen zur Stabilität kann eine dynamische Durchleuchtung respektive Magnetresonanztomographie (MRT) zusä
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