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- Associations between brain structure and perceived intensity of sweet and bitter tastes.Related ArticlesAssociations between brain structure and perceived intensity of sweet and bitter tastes. Behav Brain Res. 2019 05 02;363:103-108 Authors: Hwang LD, Strike LT, Couvy-Duchesne B, de Zubicaray GI, McMahon K, Breslin PAS, Reed DR, Martin NG, Wright MJ Abstract Functional neuroimaging studies have identified brain regions associated with human taste perception, but only a few have invest
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- Evaluation of sweetener synergy in humans by isobole analyses.Related ArticlesEvaluation of sweetener synergy in humans by isobole analyses. Chem Senses. 2019 Aug 19;: Authors: Reyes MM, Gravina SA, Hayes JE Abstract The chemical senses and pharmaceuticals fundamentally depend on similar biological processes, but novel molecule discovery has classically been approached from vastly different vantagepoints. From the perspective of ingredient and flavor companies,
- Corrigendum: Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor.Related ArticlesCorrigendum: Conserved Residues Control the T1R3-Specific Allosteric Signaling Pathway of the Mammalian Sweet-Taste Receptor. Chem Senses. 2019 Aug 17;: Authors: Chéron JB, Soohoo A, Wang Y, Golebiowski J, Antonczak S, Jiang P, Foirucci S PMID: 31420679 [PubMed - as supplied by publisher]
- Initial characterization of a subpopulation of inherent oscillatory mammalian olfactory receptor neurons.Related ArticlesInitial characterization of a subpopulation of inherent oscillatory mammalian olfactory receptor neurons. Chem Senses. 2019 Aug 17;: Authors: Ukhanov K, Bobkov YV, Martens JR, Ache BW Abstract Published evidence suggests that inherent rhythmically active or 'bursting' primary olfactory receptor neurons (bORNs) in crustaceans have the previously undescribed functional property of encod
- Injectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release and cell culture study.Related ArticlesInjectable PNIPAM/Hyaluronic acid hydrogels containing multipurpose modified particles for cartilage tissue engineering: Synthesis, characterization, drug release and cell culture study. Int J Biol Macromol. 2019 Aug 13;: Authors: Atoufi Z, Kamrava SK, Davachi SM, Hassanabadi M, Garakani SS, Alizadeh R, Farhadi M, Tavakol S, Bagher Z, Motlagh GH Abstract Novel injectable thermosensiti
- Externalization errors of olfactory source monitoring in healthy controls - an fMRI study.Related ArticlesExternalization errors of olfactory source monitoring in healthy controls - an fMRI study. Chem Senses. 2019 Aug 15;: Authors: Leclerc MP, Kellermann T, Freiherr J, Clemens B, Habel U, Regenbogen C Abstract Using a combined approach of fMRI and non-invasive brain stimulation (tDCS), the present study investigated source memory and its link to mental imagery in the olfactory domain,
- Candidates for chemosensory genes identified in the Chinese citrus fly, Bactrocera minax, through a transcriptomic analysis.Related ArticlesCandidates for chemosensory genes identified in the Chinese citrus fly, Bactrocera minax, through a transcriptomic analysis. BMC Genomics. 2019 Aug 14;20(1):646 Authors: Wu Z, Kang C, Qu M, Chen J, Chen M, Bin S, Lin J Abstract BACKGROUND: The males of many Bactrocera species (Diptera: Tephritidae) respond strongly to plant-derived chemicals (male lures) and can be divided into cue
- Women's body odor during ovulation improves social perception in single men.Related ArticlesWomen's body odor during ovulation improves social perception in single men. Chem Senses. 2019 Aug 14;: Authors: Oren C, Shamay-Tsoory SG Abstract Previous research has shown that men's mating motivation may increase following exposure to women's body odor during ovulation. In the current study we examined whether exposure to women's fertility odor cues influences social perception
- (-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells.Related Articles(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells. PLoS One. 2019;14(8):e0216024 Authors: Goren L, Zhang G, Kaushik S, Breslin PAS, Du YN, Foster DA Abstract (-)-Oleocanthal (oleocanthal) is a phenolic compound found in varying concentrations in extra virgin olive oil oleocanthal has been shown to be active physiologicall
- The senses of the choroid plexus.Related ArticlesThe senses of the choroid plexus. Prog Neurobiol. 2019 Aug 09;:101680 Authors: Santos CRA, Duarte AC, Costa AR, Tomás J, Quintela T, Gonçalves I Abstract The composition of cerebrospinal and brain interstitial fluids is ensured by barriers between the blood and the brain parenchyma (the blood-brain barrier) and between the blood and the cerebrospinal fluid (the blood-c
- Commensal bacteria regulate gene expression and differentiation in vertebrate olfactory systems through transcription factor REST.Related ArticlesCommensal bacteria regulate gene expression and differentiation in vertebrate olfactory systems through transcription factor REST. Chem Senses. 2019 Aug 12;: Authors: Casadei E, Tacchi L, Lickwar CR, Espenschied ST, Davison JM, Muñoz P, Rawls JF, Salinas I Abstract Sensory systems such as the olfactory system detect chemical stimuli and thereby determine the relationships bet
- Bcl11b controls odorant receptor class choice in mice.Related ArticlesBcl11b controls odorant receptor class choice in mice. Commun Biol. 2019;2:296 Authors: Enomoto T, Nishida H, Iwata T, Fujita A, Nakayama K, Kashiwagi T, Hatanaka Y, Kondo H, Kajitani R, Itoh T, Ohmoto M, Matsumoto I, Hirota J Abstract Each olfactory sensory neuron (OSN) expresses a single odorant receptor (OR) gene from the class I or class II repertoire in mice. The mechanisms that
- Sensing and memorising liquids with polarity-interactive ferroelectric sound.Related ArticlesSensing and memorising liquids with polarity-interactive ferroelectric sound. Nat Commun. 2019 Aug 08;10(1):3575 Authors: Kim JS, Kim EH, Park C, Kim G, Jeong B, Kim KL, Lee SW, Hwang I, Han H, Lee S, Shim W, Huh J, Park C Abstract The direct sensing and storing of the information of liquids with different polarities are of significant interest, in particular, through means related to
- A transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans.Related ArticlesA transcriptomic atlas of mammalian olfactory mucosae reveals an evolutionary influence on food odor detection in humans. Sci Adv. 2019 Jul;5(7):eaax0396 Authors: Saraiva LR, Riveros-McKay F, Mezzavilla M, Abou-Moussa EH, Arayata CJ, Makhlouf M, Trimmer C, Ibarra-Soria X, Khan M, Van Gerven L, Jorissen M, Gibbs M, O'Flynn C, McGrane S, Mombaerts P, Marioni JC, Mainland JD, Logan DW Abstract
- DPP8/9 inhibitors are universal activators of functional NLRP1 alleles.Related ArticlesDPP8/9 inhibitors are universal activators of functional NLRP1 alleles. Cell Death Dis. 2019 Aug 05;10(8):587 Authors: Gai K, Okondo MC, Rao SD, Chui AJ, Ball DP, Johnson DC, Bachovchin DA Abstract Intracellular pathogenic structures or activities stimulate the formation of inflammasomes, which recruit and activate caspase-1 and trigger an inflammatory form of cell death called pyropt
- Early rapid weight gain among formula-fed infants: Impact of formula type and maternal feeding styles.Related ArticlesEarly rapid weight gain among formula-fed infants: Impact of formula type and maternal feeding styles. Pediatr Obes. 2019 06;14(6):e12503 Authors: Mennella JA, Papas MA, Reiter AR, Stallings VA, Trabulsi JC Abstract BACKGROUND: What and how infants are fed are considered important determinants for the risk factor of early rapid gain weight. OBJECTIVES: We conducted secondar
- Temporary anosmia in mice following nasal lavage with dilute detergent solution.Related ArticlesTemporary anosmia in mice following nasal lavage with dilute detergent solution. Chem Senses. 2019 Jul 31;: Authors: Mast TG, Zuk K, Rinke A, Quasem K, Savard B, Brobbey C, Reiss J, Dryden M Abstract Olfactory sensory deprivation induces anosmia and reduces tyrosine hydroxylase and dopamine levels in the olfactory bulb. The behavioral consequences specific to the loss of olfactory bul
- Microfluidic triple-gradient generator for efficient screening of chemical space.Related ArticlesMicrofluidic triple-gradient generator for efficient screening of chemical space. Talanta. 2019 Nov 01;204:569-575 Authors: Li Y, Xuan J, Hu R, Zhang P, Lou X, Yang Y Abstract Generation of a combinatorial gradient for multiple chemicals is essential for studies of biochemical stimuli, chemoattraction, protein crystallization and others. While currently available platforms require com
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- Molecular mechanism of cytoplasmic dynein tension sensing.Related ArticlesMolecular mechanism of cytoplasmic dynein tension sensing. Nat Commun. 2019 Jul 26;10(1):3332 Authors: Rao L, Berger F, Nicholas MP, Gennerich A Abstract Cytoplasmic dynein is the most complex cytoskeletal motor protein and is responsible for numerous biological functions. Essential to dynein's function is its capacity to respond anisotropically to tension, so that its microtubule-bin
- Enhancement of the olfactory response by lipocalin Cp-Lip1 in newt olfactory receptor cells: An electrophysiological study.Related ArticlesEnhancement of the olfactory response by lipocalin Cp-Lip1 in newt olfactory receptor cells: An electrophysiological study. Chem Senses. 2019 Jul 26;: Authors: Nakamura T, Noumi Y, Yamakawa H, Nakamura A, Wen D, Li X, Geng X, Sawada K, Iwasa T Abstract Previously, we have detected the expression of two lipocalin genes (lp1 and lp2) in the olfactory epithelium of the Japanese newt Cyno
- Nuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses.Related ArticlesNuclear hnRNPA2B1 initiates and amplifies the innate immune response to DNA viruses. Science. 2019 Jul 18;: Authors: Wang L, Wen M, Cao X Abstract DNA viruses typically eject genomic DNA into the nuclei of host cells after entry. It is unclear, however, how nuclear pathogen-derived DNA triggers innate immune responses. We report that heterogeneous nuclear ribonucleoprotein A2B1 (hnR
- Corrigendum: Long-Term Taste Impairment after Intensity-Modulated Radiotherapy to Treat Head-and-Neck Cancer: Correlations with Glossectomy and the Mean Radiation Dose to the Oral Cavity.Related ArticlesCorrigendum: Long-Term Taste Impairment after Intensity-Modulated Radiotherapy to Treat Head-and-Neck Cancer: Correlations with Glossectomy and the Mean Radiation Dose to the Oral Cavity. Chem Senses. 2019 Jul 17;44(6):423 Authors: Chen WC, Tsai MS, Tsai YT, Lai CH, Lee CP, Chen MF PMID: 31313822 [PubMed - in process]
- Sensory loss enhances multisensory integration performance.Sensory loss enhances multisensory integration performance. Cortex. 2019 Jun 15;120:116-130 Authors: Peter MG, Porada DK, Regenbogen C, Olsson MJ, Lundström JN Abstract Auditory and visual sensory loss has repeatedly been shown to alter abilities in remaining sensory modalities. It is, however, unclear whether sensory loss also impacts multisensory integration; an ability that is fundamental for the
- Perception of phasic pain is modulated by smell and taste.Perception of phasic pain is modulated by smell and taste. Eur J Pain. 2019 Jul 10;: Authors: Riello M, Cecchini MP, Zanini A, Di Chiappari M, Tinazzi M, Fiorio M Abstract BACKGROUND: Pain perception is a multimodal experience composed of sensory, emotional and cognitive dimensions. Accumulating evidence suggests that the chemical senses can influence pain perception, but their relation with phasic p
- Perceptual learning in the chemical senses: A review.Perceptual learning in the chemical senses: A review. Food Res Int. 2019 Sep;123:746-761 Authors: Spence C Abstract People have been writing about perceptual learning and expertise in the chemical senses for more than a century now, with a particular focus on the world of wine. However, the problem with many of the cross-sectional studies of wine expertise that have been published to date is that the
- Insights on modulators in perception of taste modalities: a review.Related ArticlesInsights on modulators in perception of taste modalities: a review. Nutr Res Rev. 2019 Jul 08;:1-16 Authors: Deepankumar S, Karthi M, Vasanth K, Selvakumar S Abstract A major challenge in taste research is to overcome the flavour imperfections in food products and to build nutritious strategies to combat against obesity as well as other related metabolic syndromes. The field of molecu
- Contribution of parasympathetic muscarinic augmentation of insulin secretion to olanzapine-induced hyperinsulinemia.Related ArticlesContribution of parasympathetic muscarinic augmentation of insulin secretion to olanzapine-induced hyperinsulinemia. Am J Physiol Endocrinol Metab. 2018 08 01;315(2):E250-E257 Authors: Rickels MR, Perez EM, Peleckis AJ, Alshehabi E, Nguyen HL, Stefanovski D, Rickels K, Teff KL Abstract Atypical antipsychotic drugs have been associated with the development of obesity and diabetes. In
- The effect of calcium buffering and calcium sensor type on the sensitivity of an array-based bitter receptor screening assay.Related ArticlesThe effect of calcium buffering and calcium sensor type on the sensitivity of an array-based bitter receptor screening assay. Chem Senses. 2019 Jul 05;: Authors: Roelse M, Wehrens R, Henquet MGL, Witkamp RF, Hall RD, Jongsma MA Abstract The genetically encoded calcium sensor protein Cameleon YC3.6 has previously been applied for functional G protein-coupled receptor screening using re
- From biology to behavior: a cross-disciplinary seminar series surrounding added sugar and low-calorie sweetener consumption.Related ArticlesFrom biology to behavior: a cross-disciplinary seminar series surrounding added sugar and low-calorie sweetener consumption. Obes Sci Pract. 2019 Jun;5(3):203-219 Authors: Sylvetsky AC, Hiedacavage A, Shah N, Pokorney P, Baldauf S, Merrigan K, Smith V, Long MW, Black R, Robien K, Avena N, Gaine C, Greenberg D, Wootan MG, Talegawkar S, Colon-Ramos U, Leahy M, Ohmes A, Mennella JA, Sacheck J, Dietz WH
- Cerebellar grey matter and olfactory performance.Related ArticlesCerebellar grey matter and olfactory performance. Chem Senses. 2019 Jul 04;: Authors: Wabnegger A, Schienle A Abstract The role of the cerebellum in the chemical senses is still poorly understood. This voxel-based morphometry (VBM) study investigated associations between grey matter volume (GMV) in subregions of the cerebellum and olfactory performance. VBM data from 48 men were analy
- Enhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex.Related ArticlesEnhanced spontaneous DNA twisting/bending fluctuations unveiled by fluorescence lifetime distributions promote mismatch recognition by the Rad4 nucleotide excision repair complex. Nucleic Acids Res. 2018 02 16;46(3):1240-1255 Authors: Chakraborty S, Steinbach PJ, Paul D, Mu H, Broyde S, Min JH, Ansari A Abstract Rad4/XPC recognizes diverse DNA lesions including ultraviolet-photoles
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