Summary Pancreatic cancer (PC) is one of the most lethal gastrointestinal malignancies. The PTEN/AKT signalling pathway is closely related to the tumourigenesis and progression of PC. The downstream effectors, FOXO3a, PLZF and VEGF, are reported to be involved in angiogenesis, lymph node metastasis and poor survival in PC. By using tissue microarrays and immunohistochemistry, we found, that PTEN, FOXO3a and PLZF expression was significantly decreased in PC specimens compared...
5h
Abstract Biochar (BC) colloids attract increasing interest due to their unique environmental behavior and potential risks. However, the interaction between BC colloids and organic contaminants that may affect their fates in the environment has not been substantially studied. Herein, adsorption and desorption of phenanthrene (PHN), atrazine (ATZ), and oxytetracycline (OTC) by a series of BC colloids derived from bulk rice straw BC samples with 6 pyrolysis temperatures (200–700 °C),...
5h
Abstract Bioretention cell (BRC), bioretention cell with microbial fuel cell (BRC-MFC), and an enhanced combined BRC-MFC system with bimetallic zero-valent iron (BRC-MFC-BZVI) were implemented in current study to treat the domestic wastewater. Nitrogen removal characteristics of three systems were investigated by adjusting influent carbon/nitrogen ratio (C/N ratio of 2.54–19.36). Results revealed that the nitrification and denitrification performances were mainly influenced by...
8h
Abstract Nitrate leaching is a main nitrogen (N) loss pathway in vegetable production. Although there are numerous mitigation practices that control nitrate leaching, an integrated assessment of these measures is lacking. Thus, we conducted a meta-analysis to integrate the assessment of strategies for controlling nitrate leaching from vegetable systems in China. The main strategies included improved N fertilizer management (INFM), reduced water management (RWM), comprehensive regulation...
19h
Abstract In order to learn about the status of heavy metals and ecological risks in the water of thirteen China’s costal shellfish culture areas, principal component analysis was applied to analyze the distributions of five kinds of heavy metal, while the safety threshold method was employed to evaluate the ecological risks. The results showed that among the 13 shellfish culture areas, the average metal concentrations were in the order of Zn > Cu > Pb > Hg > Cd, and...
21h
Introduction and Objective: Fibroblast growth factor (FGF-23) and matrix extracellular phosphoglycoprotein (MEPE) are bone-related factors and their role in physiologic conditions and in different life stages are unknown. We aimed to evaluate age- and pregnancy-related changes in MEPE and FGF-23 levels and their correlations with calcium (Ca)-phosphate (PO4) metabolism. Methods: The study population included 96 healthy children (50 females) and 31 women (11 healthy, 10 pregnant, and 10 lactating)....
5h
In our large, multi‐institutional report of post‐prostatectomy patients with favorable‐risk prostate cancer, biopsy perineural invasion positivity was not associated with surgical Gleason score upgrading. For patients with favorable‐risk, clinically localized prostate cancer, biopsy perineural invasion alone should not be a concern for more aggressive disease requiring pathologic conformation or intervention, and these findings may help guide treatment decision‐making. Abstract Background The...
6h
Fifty‐two patients with relapsed/refractory acute myeloid leukemia (AML) were treated with clofarabine, cytarabine, and mitoxantrone. The overall response rate (ORR) was 90.4% (complete remission, CR: 69.2%; CR with incomplete hematological recovery, CRi: 21.2%), with 22 CR/CRi patients undergoing allogeneic hematopoietic stem cell transplantation (allo‐HSCT), while in CR; resulting in a 2‐year OS of 84.3% in CR patients and 90% in patients receiving allo‐HSCT. Clofarabine, cytarabine, and mitoxantrone...
6h
In this single‐institution study of CLL patients receiving ibrutinib therapy outside the context of a clinical trial, approximately 40% patients initiated ibrutinib at a reduced dose (<420 mg daily, primarily due to concomitant medications that may increase ibrutinib toxicity and physician prescribing patterns). In addition, approximately 50% patients subsequently undergo a dose modification and/or a dose interruption after initiation of ibrutinib therapy. Finally, although ibrutinib starting...
8h
ACS NanoDOI: 10.1021/acsnano.9b09299
6h
ACS NanoDOI: 10.1021/acsnano.0c00218
6h
ACS NanoDOI: 10.1021/acsnano.9b09339
6h
ACS NanoDOI: 10.1021/acsnano.9b07896
6h
ACS NanoDOI: 10.1021/acsnano.0c00836
6h
ACS NanoDOI: 10.1021/acsnano.9b09637
6h
ACS NanoDOI: 10.1021/acsnano.9b09698
10h
ACS NanoDOI: 10.1021/acsnano.9b09614
14h
ACS NanoDOI: 10.1021/acsnano.9b09880
14h
ACS NanoDOI: 10.1021/acsnano.9b10196
14h
Poonam Agrawal, Deepti Chopra, Mrinal Gupta, Santgaurav Indian Journal of Occupational and Environmental Medicine 2020 24(1):33-35 Organic solvents widely used in paint manufacturing, painting, and shoemaking industries may be associated with hepatotoxicity. We present a case report of a patient with prolonged occupational exposure to organic solvents who developed transient hepatitis. Monitoring contact to these chemicals and early identification of biological markers of occupational exposure...
6h
Sameer Vaidya, Dipti Gothi, Mahismita Patro, UC Ojha, Ram Babu SahIndian Journal of Occupational and Environmental Medicine 2020 24(1):45-46
6h
Parvaiz A Koul, Subramanium Swaminathan, Thirumalai Rajgopal, V Ramsubramanian, Bobby Joseph, Shrinivas Shanbhag, Ashish Mishra, Sidram K RautIndian Journal of Occupational and Environmental Medicine 2020 24(1):3-15 There is an increasing focus on instituting wellness programs at the workplace among organizations in India. Such programs are aimed at improving employee health, which in turn, helps in reducing absenteeism, as well as in increasing work productivity and improving employee engagement....
6h
Archana Sasi, Animesh Ray, Ashu Seith Bhalla, Sudheer Arava, Shubham Agarwal, Ranveer Singh Jadon, Naval Kishore VikramIndian Journal of Occupational and Environmental Medicine 2020 24(1):39-41 A 32-year-old gentleman, a worker in a cement-manufacturing facility with suspected silica-induced lung disease presented with acutely worsening Type 1 respiratory failure. With a negative work-up for infectious causes and no further revelations on bronchoalveolar lavage fluid or endobronchial biopsy, it...
6h
Naveen Ramesh, Archana Siddaiah, Bobby JosephIndian Journal of Occupational and Environmental Medicine 2020 24(1):16-18 Coronaviruses are zoonotic viruses and six species of Coronaviruses are known to cause human disease such as cause common cold, severe acute respiratory syndrome and the Middle East Respiratory Syndrome. In January 2020, scientists in Wuhan, China isolated a novel coronavirus (SARS-CoV-2), responsible for an outbreak of unknown pneumonia that had not been previously reported among...
6h
Sanjay Zodpey, Himanshu NegandhiIndian Journal of Occupational and Environmental Medicine 2020 24(1):1-2
6h
Febri E B. Setyawan, Stefanus Supriyanto, Ernawaty Ernawaty, Retno LestariIndian Journal of Occupational and Environmental Medicine 2020 24(1):19-24 Context: Noncompliance with personal protective equipment (PPE) in industrial workers results in increased injury or illness and is commonly reported worldwide. Numerous guidelines and management policies are employed to prevent work-related health hazards, yet industrial workers still exhibit low rates of PPE compliance, especially in outsourced workers....
6h
Mahadev Meena, Saurabh Kumar, Maya Gopalakrishnan, Gopal Krishna Bohra, Mahendra Kumar GargIndian Journal of Occupational and Environmental Medicine 2020 24(1):36-38 The reported cases of non-neonatal tetanus have doubled from 2015 to 2017 in India, while neonatal tetanus has declined by half during this period. Most of these non- neonatal tetanus are acquired by occupational exposure especially in high risk populations such as agricultural workers, industrial workers and health care workers secondary...
6h
Selvakumar Vellingiri, Priya Dutta, Srishti Singh, LM Sathish, Shyam Pingle, Bijal BrahmbhattIndian Journal of Occupational and Environmental Medicine 2020 24(1):25-29 Background: The rising global temperature and frequent heatwaves are the adverse effects of climate change. The causalities and ill impacts of the heat stress were higher among the slum dwellers because of the vulnerable household structures, which were made by heat-trapping materials like tin sheets, cement sheet (asbestos), plastic,...
6h
Sonam Spalgais, Raj Kumar, Parul MrgipuriIndian Journal of Occupational and Environmental Medicine 2020 24(1):42-44 Pulmonary siderosis is a rare occupational lung disease. Traditionally, it has been considered a “benign pneumoconiosis” because of the absence of associated clinical symptoms or pulmonary fibrosis. However, few authors have reported the evidence of pulmonary symptoms with lung fibrosis on high-resolution computed tomography and lung biopsy. Symptomatic pulmonary siderosis in scissors/knife...
6h
Sonal Gawande, Rajnarayan R Tiwari, Prakash Narayanan, Ashwin BhadriIndian Journal of Occupational and Environmental Medicine 2020 24(1):30-32 Indoor air quality (IAQ) influences human health, productivity and wellness. Green buildings are believed to have better IAQ. The 'sick building syndrome' (SBS) describes a set of nonspecific symptoms experienced by occupants due to time spent in a building with poor IAQ. Thus this study was undertaken to assess the IAQ in green buildings and compare it...
6h
Thana Khawcharoenporn, Waralee Aksornchindarat, Napat Yodpinij, Sopa Srisungngam, Janisara Rudeeaneksin, Supranee Bunchoo, Wiphat Klayut, Somchai Sangkitporn, Benjawan PhetsuksiriIndian Journal of Occupational and Environmental Medicine 2020 24(1):47-49
6h
Immune checkpoint inhibitors (ICI) are an integral part of bladder cancer therapy, however, the relevance of ICI treatment for mixed and pure squamous cell carcinoma of the bladder remains poorly studied. Ther...
7h
Prophylactic cranial irradiation (PCI) is a current standard of care after confirmed response to radical chemoradiotherapy for limited disease small cell lung cancer (LD-SCLC). This standard is mostly based on...
7h
Corrigendum to “Early Results of Lung Cancer Screening and Radiation Dose Assessment by Low-dose CT at a Community Hospital” [Clinical Lung Cancer. 2017 Sept;18(5): e327-331]
7h
We write in reply to the comprehensive and insightful letter from Dr Pashankar and Dr Frazier regarding our article, ‘A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice’[1].
7h
A coalition of professional imaging organizations in Australia is urging the...Read more on AuntMinnieEurope.com
7h
Radiopharmaceutical firm Radio Pharma Logistics Group (RLG) has pledged to...Read more on AuntMinnieEurope.com
8h
Researchers from the U.K. and Sweden have created a realistic 3D-printed brain...Read more on AuntMinnieEurope.comRelated Reading: Spanish team visualizes 3D patient models on smartphones 3D printing assists ultrasound-guided liver resection Cardiac patients gain from 3D printing, AR advances 3D printing boosts treatment of urethral injuries Italians use 3D printing to enhance safety in upper GI surgery
13h
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου