Πέμπτη 19 Μαρτίου 2020


Tumor microenvironment characterization identifies two lung adenocarcinoma subtypes with specific immune and metabolic state
ABSTRACT Tumor microenvironment (TME) are vital components of tumor tissue. Increasing evidence suggest their significance in predicting outcomes and guiding therapies. However, no studies have reported a systematic analysis of clinicopathological significance of TME in lung adenocarcinoma (LUAD). Here, we inferred tumor stromal cells in 1,184 LUAD patients using computational algorithms based on bulk tumor expression data, and evaluated clinicopathological significance of stromal cells. We found...
Cancer Science
5m
How radiology can prepare for coronavirus crisis
An international team of medical imaging specialists has issued a list of best...Read more on AuntMinnieEurope.comRelated Reading: Report: Radiology seminar linked to COVID-19 spread Imaging experts strive to get a grip on COVID-19 Chest CT beats DNA tests for early coronavirus diagnosis Italy gears up for spread of coronavirus CT 'paramount' for early diagnosis of novel coronavirus
AuntMinnieEurope.com Headlines
5m
IJMS, Vol. 21, Pages 2099: Hormesis in Plants: The Role of Oxidative Stress, Auxins and Photosynthesis in Corn Treated with Cd or Pb
IJMS, Vol. 21, Pages 2099: Hormesis in Plants: The Role of Oxidative Stress, Auxins and Photosynthesis in Corn Treated with Cd or Pb International Journal of Molecular Sciences doi: 10.3390/ijms21062099 Authors: Eugeniusz Małkowski Krzysztof Sitko Michał Szopiński Żaneta Gieroń Marta Pogrzeba Hazem M. Kalaji Paulina Zieleźnik-Rusinowska Hormesis, which describes the stimulatory effect of low doses of toxic substances on growth, is a well-known phenomenon...
International Journal of Molecular Sciences
7m
Cranial Base Manifestations of Granulomatosis with Polyangiitis.
Related ArticlesCranial Base Manifestations of Granulomatosis with Polyangiitis. Otolaryngol Head Neck Surg. 2020 Mar 17;:194599820912025 Authors: Kiessling PT, Marinelli JP, Peters PA, DeLone DR, Lane JI, Koster MJ, Carlson ML Abstract OBJECTIVE: Although granulomatosis with polyangiitis (GPA; Wegener's granulomatosis) is classically characterized by systemic disease involving the kidneys and airway, approximately 10% of patients who have it present...
AA pubmed: head and neck
20h
Influence of Age at Cochlear Implantation and Frequency-to-Place Mismatch on Early Speech Recognition in Adults.
Related ArticlesInfluence of Age at Cochlear Implantation and Frequency-to-Place Mismatch on Early Speech Recognition in Adults. Otolaryngol Head Neck Surg. 2020 Mar 17;:194599820911707 Authors: Canfarotta MW, O'Connell BP, Buss E, Pillsbury HC, Brown KD, Dillon MT Abstract OBJECTIVE: Default frequency filters of cochlear implant (CI) devices assign frequency information irrespective of intracochlear position, resulting in varying degrees of frequency-to-place...
AA pubmed: head and neck
20h
Elevated Central and Mixed Apnea Index after Upper Airway Stimulation.
Related ArticlesElevated Central and Mixed Apnea Index after Upper Airway Stimulation. Otolaryngol Head Neck Surg. 2020 Mar 17;:194599820912740 Authors: Patel J, Daniels K, Bogdan L, Huntley C, Boon M Abstract OBJECTIVE: Upper airway stimulation (UAS) is used to treat patients with moderate to severe obstructive sleep apnea (OSA). The aim of this study is to report the incidence and potential predictors of elevated central and mixed apnea index (CMAI)...
AA pubmed: head and neck
20h
LY6D as a chemoresistance marker gene and therapeutic target for laryngeal squamous cell carcinoma.
Related ArticlesLY6D as a chemoresistance marker gene and therapeutic target for laryngeal squamous cell carcinoma. Stem Cells Dev. 2020 Mar 17;: Authors: Wang J, Fan J, Gao W, Wu Y, Zhao Q, Chen B, Ding Y, Wen S, Nan X, Wang B Abstract Laryngeal squamous cell carcinoma (LSCC) is a common head and neck cancer that is unresponsive to chemotherapy; therefore, understanding the causes of chemotherapy resistance is important. The cancer stem cell theory...
AA pubmed: head and neck
20h
Supportive Care Needs of Patients with Head and Neck Cancer Referred to Palliative Medicine.
Related ArticlesSupportive Care Needs of Patients with Head and Neck Cancer Referred to Palliative Medicine. Otolaryngol Head Neck Surg. 2020 Mar 17;:194599820912029 Authors: Lin C, Kang SY, Donermeyer S, Teknos TN, Wells-Di Gregorio SM Abstract OBJECTIVE: Patients with head and neck cancer (HNC) face a unique set of unmet needs. A subset of these patients experience symptom control challenges related to their disease burden and treatments. A multidisciplinary...
AA pubmed: head and neck
20h
Influence of Sevoflurane-Based Anesthesia versus Total Intravenous Anesthesia on Intraoperative Neuromonitoring during Thyroidectomy.
Related ArticlesInfluence of Sevoflurane-Based Anesthesia versus Total Intravenous Anesthesia on Intraoperative Neuromonitoring during Thyroidectomy. Otolaryngol Head Neck Surg. 2020 Mar 17;:194599820912030 Authors: Li X, Zhang B, Yu L, Yang J, Tan H Abstract OBJECTIVE: To examine the influence of sevoflurane-based combined intravenous and inhaled anesthesia versus propofol-based total intravenous anesthesia (TIVA) on intraoperative neuromonitoring...
AA pubmed: head and neck
20h
Barrier Protection Measures for the Management of Allergic Rhinitis: A Systematic Review and Meta-analysis.
Related ArticlesBarrier Protection Measures for the Management of Allergic Rhinitis: A Systematic Review and Meta-analysis. Am J Rhinol Allergy. 2020 Mar 16;:1945892420912370 Authors: Chen X, Deng C, Mi J, Chen M, Li Y, Liu Z, Feng S PMID: 32178523 [PubMed - as supplied by publisher]
AA pubmed: head and neck
20h
Long-Term Surveillance of Antibiotic Prescriptions and the Prevalence of Antimicrobial Resistance in Non-Fermenting Gram-Negative Bacilli.
Related ArticlesLong-Term Surveillance of Antibiotic Prescriptions and the Prevalence of Antimicrobial Resistance in Non-Fermenting Gram-Negative Bacilli. Microorganisms. 2020 Mar 12;8(3): Authors: Chou CH, Lai YR, Chi CY, Ho MW, Chen CL, Liao WC, Ho CM, Chen YA, Chen CY, Lin YT, Lin CD, Lai CH Abstract The increasing emergence of multidrug-resistant (MDR) bacteria has been recognized as a public health threat worldwide. Hospitalized patients and...
AA pubmed: head and neck
20h
Impaired Release of Neutrophil Extracellular Traps and Anemia-Associated T Cell Deficiency in Hereditary Hemorrhagic Telangiectasia.
Related ArticlesImpaired Release of Neutrophil Extracellular Traps and Anemia-Associated T Cell Deficiency in Hereditary Hemorrhagic Telangiectasia. J Clin Med. 2020 Mar 12;9(3): Authors: Droege F, Pylaeva E, Siakaeva E, Bordbari S, Spyra I, Thangavelu K, Lueb C, Domnich M, Lang S, Geisthoff U, Jablonska J Abstract Hereditary hemorrhagic telangiectasia (HHT) is characterized by mucocutaneous telangiectases and visceral vascular malformations. Individuals...
AA pubmed: head and neck
20h
Trametinib and Dabrafenib in histiocytic sarcoma transdifferentiated from chronic lymphocytic leukemia with a K-RAS and a unique BRAF mutation.
Related ArticlesTrametinib and Dabrafenib in histiocytic sarcoma transdifferentiated from chronic lymphocytic leukemia with a K-RAS and a unique BRAF mutation. Ann Hematol. 2020 Mar;99(3):649-651 Authors: Rassidakis GZ, Stromberg O, Xagoraris I, Jatta K, Sonnevi K PMID: 32009180 [PubMed - indexed for MEDLINE]
AA pubmed: head and neck
20h
ABO Genotype and Blood Type Are Associated with Otitis Media.
Related ArticlesABO Genotype and Blood Type Are Associated with Otitis Media. Genet Test Mol Biomarkers. 2019 Nov;23(11):823-827 Authors: Wiesen BM, Hafrén L, Einarsdottir E, Kere J, Mattila PS, Santos-Cortez RLP Abstract Aim: To determine if there is an association between ABO variants or blood types and otitis media. Methods: DNA samples from 214 probands from Finnish families with recurrent acute (RAOM) and/or chronic otitis media with effusion...
AA pubmed: head and neck
20h
The effect of low resolution and coverage on the accuracy of susceptibility mapping.
Related ArticlesThe effect of low resolution and coverage on the accuracy of susceptibility mapping. Magn Reson Med. 2019 03;81(3):1833-1848 Authors: Karsa A, Punwani S, Shmueli K Abstract PURPOSE: Quantitative susceptibility mapping (QSM) has found increasing clinical applications. However, to reduce scan time, clinical acquisitions often use reduced resolution and coverage, particularly in the through-slice dimension. The effect of these factors...
AA pubmed: head and neck
20h
Correction to: Targeted Anti-IL-5 Therapies and Future Therapeutics for Hypereosinophilic Syndrome and Rare Eosinophilic Conditions
The original version of this article unfortunately contained a mistake in the fifth paragraph of the “Conclusion” section.
Latest Results for Clinical Reviews in Allergy
20h
Stem cell-loaded adhesive immiscible liquid for regeneration of myocardial infarction
Publication date: 10 May 2020Source: Journal of Controlled Release, Volume 321Author(s): Tae Yoon Park, Jeong-min Oh, Jung Sun Cho, Sung Bo Sim, Jongho Lee, Hyung Joon Cha
ScienceDirect Publication: Journal of Controlled Release
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Polyplex transfection from intracerebroventricular delivery is not significantly affected by traumatic brain injury
Publication date: Available online 18 March 2020Source: Journal of Controlled ReleaseAuthor(s): David J. Peeler, Nicholas Luera, Philip J. Horner, Suzie H. Pun, Drew L. Sellers
ScienceDirect Publication: Journal of Controlled Release
20h
Evasion of the accelerated blood clearance phenomenon by polysarcosine coating of liposomes
Publication date: Available online 17 March 2020Source: Journal of Controlled ReleaseAuthor(s): Kon Son, Motoki Ueda, Kazuaki Taguchi, Toru Maruyama, Shinji Takeoka, Yoshihiro Ito
ScienceDirect Publication: Journal of Controlled Release
20h
Transdermal siRNA delivery by pH-switchable micelles with targeting effect suppress skin melanoma progression
Publication date: Available online 17 March 2020Source: Journal of Controlled ReleaseAuthor(s): Mao-Ze Wang, Jie Niu, Hui-Jian Ma, Haseeb Anwar Dad, Hai-Tao Shao, Tie-Jun Yuan, Li-Hua Peng
ScienceDirect Publication: Journal of Controlled Release
20h
Current innovations in otolaryngology medical education in the UK: a systematic literature review.
Related ArticlesCurrent innovations in otolaryngology medical education in the UK: a systematic literature review. J Laryngol Otol. 2020 Mar 17;:1-9 Authors: Yip HM, Soh TCF, Lim ZZ Abstract OBJECTIVE: Recent studies have indicated a lack of ENT training at the undergraduate and post-graduate levels. This study aimed to review the impact of recent educational innovations in improving ENT training for medical students and junior doctors in the UK. ...
Laryngology and otology
21h
Relationship between Beck Hopelessness Scale and suicidal ideation: A short-term longitudinal study
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Death Studies: Table of Contents: Taylor and Francis
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Bonus time: A gay man’s experience as a long-term HIV survivor
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Death Studies: Table of Contents: Taylor and Francis
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Mind the gap between feeling bad and feeling dead: Stress but not death reminders elicit endocrine responses
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Death Studies: Table of Contents: Taylor and Francis
21h
[Taking care, right here, right now: Why medicine should be inspired by the philosophy of Albert Camus?]
Related Articles[Taking care, right here, right now: Why medicine should be inspired by the philosophy of Albert Camus?] Bull Cancer. 2020 Mar;107(3):289-291 Authors: Blot F PMID: 32178792 [PubMed - in process]
pubmed: philosophy for medic...
21h
Improving researchers' conflict of interest declarations.
Related ArticlesImproving researchers' conflict of interest declarations. BMJ. 2020 Mar 11;368:m422 Authors: Grundy Q, Dunn AG, Bero L PMID: 32161006 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
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Inappropriate use of progression-free survival in cancer drug approvals.
Related ArticlesInappropriate use of progression-free survival in cancer drug approvals. BMJ. 2020 Mar 10;368:m770 Authors: Naci H, Davis C PMID: 32156802 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
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Peer support for discharge from inpatient to community mental health services: Study protocol clinical trial (SPIRIT Compliant).
Related ArticlesPeer support for discharge from inpatient to community mental health services: Study protocol clinical trial (SPIRIT Compliant). Medicine (Baltimore). 2020 Mar;99(10):e19192 Authors: Gillard S, Bremner S, Foster R, Gibson SL, Goldsmith L, Healey A, Lucock M, Marks J, Morshead R, Patel A, Priebe S, Repper J, Rinaldi M, Roberts S, Simpson A, White S Abstract INTRODUCTION: In the period shortly after discharge from inpatient to community...
pubmed: philosophy for medic...
21h
The effect of transcranial direct current stimulation of pharyngeal motor cortex on swallowing function in patients with chronic dysphagia after stroke: A retrospective cohort study.
Related ArticlesThe effect of transcranial direct current stimulation of pharyngeal motor cortex on swallowing function in patients with chronic dysphagia after stroke: A retrospective cohort study. Medicine (Baltimore). 2020 Mar;99(10):e19121 Authors: Li Y, Feng H, Li J, Wang H, Chen N, Yang J Abstract About 11% to 13% of patients with acute dysphagia induced by stroke remain chronic dysphagia 6 months after stroke which usually leads to many severe...
pubmed: philosophy for medic...
21h
What Are Two Days Worth? Facing Dilemmas Together at the End of Life.
Related ArticlesWhat Are Two Days Worth? Facing Dilemmas Together at the End of Life. N Engl J Med. 2020 Mar 05;382(10):890-891 Authors: Rosenberg LB PMID: 32130812 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
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Bridging Polarization in Medicine - From Biology to Social Causes.
Related ArticlesBridging Polarization in Medicine - From Biology to Social Causes. N Engl J Med. 2020 Mar 05;382(10):888-889 Authors: Armstrong K, Asch DA PMID: 32130811 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
21h
[Professor YANG Jun's clinical characteristics in the treatment of chronic diarrhea with acupuncture and herbal medicine based on qi activity theory in Huangdi Neijing].
Related Articles[Professor YANG Jun's clinical characteristics in the treatment of chronic diarrhea with acupuncture and herbal medicine based on qi activity theory in Huangdi Neijing]. Zhongguo Zhen Jiu. 2020 Feb 12;40(2):207-10 Authors: Zhou C, Nie DR, Yuan AH, Yang J Abstract Professor YANG Jun believes that chronic diarrhea is located in the "intestine" and its pathogenesis focuses on the dysfunction of the spleen and the stomach which results in...
pubmed: philosophy for medic...
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[Professor WANG Fu-chun's experience of four elements of acupuncture manipulation practice].
Related Articles[Professor WANG Fu-chun's experience of four elements of acupuncture manipulation practice]. Zhongguo Zhen Jiu. 2020 Feb 12;40(2):203-5 Authors: Zhao JY, Wang FC, Jiang HL, Li T Abstract Through collecting the 30-year medical experience of professor WANG Fu-chun, the methods of acupuncture manipulation practice were summarized so as to provide the reference for the medical staffs in acupuncture teaching and clinical work. Professor WANG...
pubmed: philosophy for medic...
21h
Whole body vibration training during allogeneic hematopoietic cell transplantation-the effects on patients' physical capacity.
Related ArticlesWhole body vibration training during allogeneic hematopoietic cell transplantation-the effects on patients' physical capacity. Ann Hematol. 2020 Mar;99(3):635-648 Authors: Pahl A, Wehrle A, Kneis S, Gollhofer A, Bertz H Abstract Patients undergoing allogeneic hematopoietic cell transplantation (alloHCT) experience a considerable decline in physical and psycho-social capacity. Since whole body vibration (WBV) is known to efficiently stimulate...
pubmed: philosophy for medic...
21h
The effect of therapeutic drug monitoring of beta-lactam and fluoroquinolones on clinical outcome in critically ill patients: the DOLPHIN trial protocol of a multi-centre randomised controlled trial.
Related ArticlesThe effect of therapeutic drug monitoring of beta-lactam and fluoroquinolones on clinical outcome in critically ill patients: the DOLPHIN trial protocol of a multi-centre randomised controlled trial. BMC Infect Dis. 2020 Jan 17;20(1):57 Authors: Abdulla A, Ewoldt TMJ, Hunfeld NGM, Muller AE, Rietdijk WJR, Polinder S, van Gelder T, Endeman H, Koch BCP Abstract BACKGROUND: Critically ill patients undergo extensive physiological alterations...
pubmed: philosophy for medic...
21h
[Moral distress among non-medical healthcare professionals: A collateral effect of defensive medicine].
Related Articles[Moral distress among non-medical healthcare professionals: A collateral effect of defensive medicine]. J Healthc Qual Res. 2019 Nov - Dec;34(6):335-336 Authors: Cruz-Valiño AB PMID: 31787220 [PubMed - indexed for MEDLINE]
pubmed: philosophy for medic...
21h
The impact of physical exercise on cognitive and affective functions and serum levels of brain-derived neurotrophic factor in nursing home residents: A randomized controlled trial.
Related ArticlesThe impact of physical exercise on cognitive and affective functions and serum levels of brain-derived neurotrophic factor in nursing home residents: A randomized controlled trial. Maturitas. 2020 Jan;131:72-77 Authors: Arrieta H, Rezola-Pardo C, Kortajarena M, Hervás G, Gil J, Yanguas JJ, Iturburu M, Gil SM, Irazusta J, Rodriguez-Larrad A Abstract OBJECTIVES: To determine the effects of a multicomponent physical exercise program on...
pubmed: philosophy for medic...
21h
[The Social Pact for the Non-discrimination and Equal Treatment Associated with HIV development].
Related Articles[The Social Pact for the Non-discrimination and Equal Treatment Associated with HIV development]. Rev Esp Salud Publica. 2019 Dec 02;93: Authors: Koerting A, Polo R, Vázquez MC, Del Amo J Abstract Advances in treatment and care have improved the life expectancy and quality of life for people living with HIV. However, those infected with HIV remain exposed to the social stigma that continues to be associated with this condition and sometimes...
pubmed: philosophy for medic...
21h
[Effects of polypharmacy and anticholinergic/sedative drugs on the physical/cognitive/mental related outcomes of community-dwelling elderly people: The Kawasaki Wellbeing Project].
Related Articles[Effects of polypharmacy and anticholinergic/sedative drugs on the physical/cognitive/mental related outcomes of community-dwelling elderly people: The Kawasaki Wellbeing Project]. Nihon Ronen Igakkai Zasshi. 2019;56(4):504-515 Authors: Tanaka A, Arai Y, Hirata T, Abe Y, Oguma Y, Urushihara H Abstract AIM: To assess the burdens of polypharmacy and the drug burden index in community-dwelling elder people. METHODS: The survey...
pubmed: philosophy for medic...
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