IJMS, Vol. 20, Pages 3847: Matrix Metalloproteases as Influencers of the Cells’ Social Media International Journal of Molecular Sciences doi: 10.3390/ijms20163847 Authors: Daniel Young Nabangshu Das Anthonia Anowai Antoine Dufour Matrix metalloproteinases (MMPs) have been studied in the context of cancer due to their ability to increase cell invasion, and were initially thought to facilitate metastasis solely through the degradation of the extracellular matrix (ECM). MMPs have...
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IJMS, Vol. 20, Pages 3848: Complexity of Generating Mouse Models to Study the Upper Motor Neurons: Let Us Shift Focus from Mice to Neurons International Journal of Molecular Sciences doi: 10.3390/ijms20163848 Authors: Baris Genc Oge Gozutok P. Hande Ozdinler Motor neuron circuitry is one of the most elaborate circuitries in our body, which ensures voluntary and skilled movement that requires cognitive input. Therefore, both the cortex and the spinal cord are involved. The cortex...
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IJMS, Vol. 20, Pages 3846: Gene Modules Co-regulated with Biosynthetic Gene Clusters for Allelopathy between Rice and Barnyardgrass International Journal of Molecular Sciences doi: 10.3390/ijms20163846 Authors: Most. Humaira Sultana Fangjie Liu Md. Alamin Lingfeng Mao Lei Jia Hongyu Chen Dongya Wu Yingying Wang Fei Fu Sanling Wu Weidi Wang Chuyu Ye Qian-Hao Zhu Jie Qiu Longjiang Fan Allelopathy is a central process in crop–weed interactions...
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IJMS, Vol. 20, Pages 3844: Blockade of TRPV2 is a Novel Therapy for Cardiomyopathy in Muscular Dystrophy International Journal of Molecular Sciences doi: 10.3390/ijms20163844 Authors: Yuko Iwata Tsuyoshi Matsumura Muscular dystrophy and dilated cardiomyopathy are intractable diseases and their treatment options are very limited. Transient receptor potential cation channel subfamily V, member 2 (TRPV2), is a stretch-sensitive Ca2+-permeable channel that causes sustained intracellular...
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IJMS, Vol. 20, Pages 3845: Osteostatin Inhibits Collagen-Induced Arthritis by Regulation of Immune Activation, Pro-Inflammatory Cytokines, and Osteoclastogenesis International Journal of Molecular Sciences doi: 10.3390/ijms20163845 Authors: Josep Nácher-Juan María Carmen Terencio María José Alcaraz María Luisa Ferrándiz In chronic inflammatory joint diseases, such as rheumatoid arthritis, there is an important bone loss. Parathyroid hormone-related protein (PTHrP) and related...
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IJMS, Vol. 20, Pages 3843: Olmesartan Attenuates Kidney Fibrosis in a Murine Model of Alport Syndrome by Suppressing Tubular Expression of TGFβ International Journal of Molecular Sciences doi: 10.3390/ijms20153843 Authors: Suh Choi Kim Kim Ma Scholey Kim Bae Despite the wide use of angiotensin II receptor blockers in the treatment of Alport syndrome (AS), the mechanism as to how angiotensin II receptor blockers prevent interstitial fibrosis remains unclear....
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3841: Role of Carbonic Anhydrases and Inhibitors in Acid–Base Physiology: Insights from Mathematical Modeling International Journal of Molecular Sciences doi: 10.3390/ijms20153841 Authors: Occhipinti Boron Carbonic anhydrases (CAs) catalyze a reaction fundamental for life: the bidirectional conversion of carbon dioxide (CO2) and water (H2O) into bicarbonate (HCO3−) and protons (H+). These enzymes impact numerous physiological processes that occur within...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3836: A Hydroquinone-Based Derivative Elicits Apoptosis and Autophagy via Activating a ROS-Dependent Unfolded Protein Response in Human Glioblastoma International Journal of Molecular Sciences doi: 10.3390/ijms20153836 Authors: Silvia Zappavigna Alessia Maria Cossu Marianna Abate Gabriella Misso Angela Lombardi Michele Caraglia Rosanna Filosa 5-Lipoxygenase (5-LO) has been reported to be highly expressed in brain tumors and to promote glioma cell...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3842: Epigenetic Biomarkers in Colorectal Cancer Patients Receiving Adjuvant or Neoadjuvant Therapy: A Systematic Review of Epidemiological Studies International Journal of Molecular Sciences doi: 10.3390/ijms20153842 Authors: Barchitta Maugeri Destri Basile Agodi Colorectal cancer (CRC) represents the third-most common cancer worldwide and one of the main challenges for public health. Despite great strides in the application of neoadjuvant and adjuvant...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3840: The Development of Tetrazole Derivatives as Protein Arginine Methyltransferase I (PRMT I) Inhibitors International Journal of Molecular Sciences doi: 10.3390/ijms20153840 Authors: Sun Wang Yang Zhu Wu Ma Xu Hong Wang Protein arginine methyltransferase 1 (PRMT1) can catalyze protein arginine methylation by transferring the methyl group from S-adenosyl-L-methionine (SAM) to the guanidyl nitrogen atom of protein arginine, which...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3839: Tobacco Cutworm (Spodoptera Litura) Larvae Silenced in the NADPH-Cytochrome P450 Reductase Gene Show Increased Susceptibility to Phoxim International Journal of Molecular Sciences doi: 10.3390/ijms20153839 Authors: Hong-Yi Ji Christian Staehelin Yan-Ping Jiang Shi-Wei Liu Zhi-Hui Ma Yi-Juan Su Jia-En Zhang Rui-Long Wang Nicotinamide adenine dinucleotide phosphate (NADPH)-cytochrome P450 reductases (CPRs) function as redox partners of cytochrome...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3837: Retrotransposons in Plant Genomes: Structure, Identification, and Classification through Bioinformatics and Machine Learning International Journal of Molecular Sciences doi: 10.3390/ijms20153837 Authors: Simon Orozco-Arias Gustavo Isaza Romain Guyot Transposable elements (TEs) are genomic units able to move within the genome of virtually all organisms. Due to their natural repetitive numbers and their high structural diversity, the identification and...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3838: Recent Progress in the Regeneration of Spinal Cord Injuries by Induced Pluripotent Stem Cells International Journal of Molecular Sciences doi: 10.3390/ijms20153838 Authors: Maria Csobonyeiova Stefan Polak Radoslav Zamborsky Lubos Danisovic Regeneration of injuries occurring in the central nervous system, particularly spinal cord injuries (SCIs), is extremely difficult. The complex pathological events following a SCI often restrict regeneration of nervous...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3835: Biological Response to Macroporous Chitosan-Agarose Bone Scaffolds Comprising Mg- and Zn-Doped Nano-Hydroxyapatite International Journal of Molecular Sciences doi: 10.3390/ijms20153835 Authors: Paulina Kazimierczak Joanna Kolmas Agata Przekora Modification of implantable scaffolds with magnesium and zinc for improvement of bone regeneration is a growing trend in the engineering of biomaterials. The aim of this study was to synthesize nano-hydroxyapatite...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3834: Sequence and Evolutionary Features for the Alternatively Spliced Exons of Eukaryotic Genes International Journal of Molecular Sciences doi: 10.3390/ijms20153834 Authors: Shi-Yi Chen Cao Li Xianbo Jia Song-Jia Lai Alternative splicing of pre-mRNAs is a crucial mechanism for maintaining protein diversity in eukaryotes without requiring a considerable increase of genes in the number. Due to rapid advances in high-throughput sequencing technologies and...
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3833: Current Knowledge of the Potential Links between Inflammation and Prostate Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20153833 Authors: Tommaso Cai Raffaella Santi Irene Tamanini Ilaria Camilla Galli Gianpaolo Perletti Truls E. Bjerklund Johansen Gabriella Nesi Inflammation is inherent in prostatic diseases and it is now accepted that it may facilitate cellular proliferation in both benign and malignant conditions....
Tue Aug 06, 2019 03:00
IJMS, Vol. 20, Pages 3831: The Activation Status of the TGF-β Transducer Smad2 Is Associated with a Reduced Survival in Gastrointestinal Cancers: A Systematic Review and Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20153831 Authors: Ilaria Girolami Nicola Veronese Lee Smith Maria G. Caruso Rosa Reddavide Gioacchino Leandro Jacopo Demurtas Alessia Nottegar Aberrant function of Smad2, a crucial member of transforming growth factor beta...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3829: High-Fat Feeding in Time-Dependent Manner Affects Metabolic Routes Leading to Nervonic Acid Synthesis in NAFLD International Journal of Molecular Sciences doi: 10.3390/ijms20153829 Authors: Konstantynowicz-Nowicka Berk Chabowski Kasacka Bielawiec Łukaszuk Harasim-Symbor Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive lipid accumulation in the liver. The disturbances in the fatty acid composition of stored lipids...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3832: A Narrative Role of Vitamin D and Its Receptor: With Current Evidence on the Gastric Tissues International Journal of Molecular Sciences doi: 10.3390/ijms20153832 Authors: Sirajudeen Shah Al Menhali Vitamin D is a major steroid hormone that is gaining attention as a therapeutic molecule. Due to the general awareness of its importance for the overall well-being, vitamin D deficiency (VDD) is now recognized as a major health issue. The main reason for...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3830: Biochemistry of Copper Site Assembly in Heme-Copper Oxidases: A Theme with Variations International Journal of Molecular Sciences doi: 10.3390/ijms20153830 Authors: María-Eugenia Llases Marcos N. Morgada Alejandro J. Vila Copper is an essential cofactor for aerobic respiration, since it is required as a redox cofactor in Cytochrome c Oxidase (COX). This ancient and highly conserved enzymatic complex from the family of heme-copper oxidase possesses two...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3826: Periodontal Therapy for Improving Lipid Profiles in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis International Journal of Molecular Sciences doi: 10.3390/ijms20153826 Authors: Siddharth Garde Rahena Akhter Mai Anh Nguyen Clara K. Chow Joerg Eberhard Periodontitis is a chronic inflammatory disorder often seen in patients with diabetes mellitus (DM). Individuals with diabetes are at a greater risk of developing cardiovascular...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3827: Current Strategies to Enhance Adipose Stem Cell Function: An Update International Journal of Molecular Sciences doi: 10.3390/ijms20153827 Authors: Yoojin Seo Tae-Hoon Shin Hyung-Sik Kim Mesenchymal stem cells (MSCs) emerged as a promising therapeutic tool targeting a variety of inflammatory disorders due to their multiple remarkable properties, such as superior immunomodulatory function and tissue-regenerative capacity. Although bone marrow (BM) is a...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3828: Comparative Analysis of two Sugarcane Ancestors Saccharum officinarum and S. spontaneum based on Complete Chloroplast Genome Sequences and Photosynthetic Ability in Cold Stress International Journal of Molecular Sciences doi: 10.3390/ijms20153828 Authors: Fu Xu Lilian He Shiwu Gao Yachun Su Fusheng Li Liping Xu Polyploid Saccharum with complex genomes hindered the progress of sugarcane improvement, while their chloroplast genomes are much smaller...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3824: The Autophagy Status of Cancer Stem Cells in Gliobastoma Multiforme: From Cancer Promotion to Therapeutic Strategies International Journal of Molecular Sciences doi: 10.3390/ijms20153824 Authors: Larisa Ryskalin Anderson Gaglione Fiona Limanaqi Francesca Biagioni Pietro Familiari Alessandro Frati Vincenzo Esposito Francesco Fornai Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor featuring rapid cell proliferation,...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3825: Liquid Biopsy as a Tool for Differentiation of Leiomyomas and Sarcomas of Corpus Uteri International Journal of Molecular Sciences doi: 10.3390/ijms20153825 Authors: Dana Dvorská Henrieta Škovierová Dušan Braný Erika Halašová Zuzana Danková Utilization of liquid biopsy in the management of cancerous diseases is becoming more attractive. This method can overcome typical limitations of tissue biopsies, especially invasiveness, no repeatability, and...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3822: Progesterone and Estrogen Signaling in the Endometrium: What Goes Wrong in Endometriosis? International Journal of Molecular Sciences doi: 10.3390/ijms20153822 Authors: Ryan M. Marquardt Tae Hoon Kim Jung-Ho Shin Jae-Wook Jeong In the healthy endometrium, progesterone and estrogen signaling coordinate in a tightly regulated, dynamic interplay to drive a normal menstrual cycle and promote an embryo-receptive state to allow implantation during the window...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3818: Identification and Clinical Validation of a Novel 4 Gene-Signature with Prognostic Utility in Colorectal Cancer International Journal of Molecular Sciences doi: 10.3390/ijms20153818 Authors: Pankaj Ahluwalia Ashis K. Mondal Chance Bloomer Sadanand Fulzele Kimya Jones Sudha Ananth Gagandeep K. Gahlay Saleh Heneidi Amyn M. Rojiani Vamsi Kota Ravindra Kolhe Colorectal cancer (CRC) is a high burden disease with several genes involved...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3821: Epidermal Growth Factor Receptor (EGFR) Pathway, Yes-Associated Protein (YAP) and the Regulation of Programmed Death-Ligand 1 (PD-L1) in Non-Small Cell Lung Cancer (NSCLC) International Journal of Molecular Sciences doi: 10.3390/ijms20153821 Authors: Ping-Chih Hsu David M. Jablons Cheng-Ta Yang Liang You The epidermal growth factor receptor (EGFR) pathway is a well-studied oncogenic pathway in human non-small cell lung cancer (NSCLC). A subset of advanced...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3820: Anti-Proliferative and Pro-Apoptotic Effects of Licochalcone A through ROS-Mediated Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells International Journal of Molecular Sciences doi: 10.3390/ijms20153820 Authors: Su Hyun Hong Hee-Jae Cha Hyun Hwang-Bo Min Yeong Kim So Young Kim Seon Yeong Ji JaeHun Cheong Cheol Park Hyesook Lee Gi-Young Kim Sung-Kwon Moon Seok Joong Yun Young-Chae Chang Wun-Jae Kim Yung Hyun Choi...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3819: Activity Coefficients for Liquid Organic Reactions: Towards a Better Understanding of True Kinetics with the Synthesis of Jasmin Aldehyde as Showcase International Journal of Molecular Sciences doi: 10.3390/ijms20153819 Authors: Philippe M. Heynderickx The aldol condensation of benzaldehyde and heptanal is taken as an example of reversible liquid phase organic reactions to show that inclusion of activity coefficients reveal distinct differences in conversion...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3817: Protein Phosphatase Ppz1 Is Not Regulated by a Hal3-Like Protein in Plant Pathogen Ustilago maydis International Journal of Molecular Sciences doi: 10.3390/ijms20153817 Authors: Chunyi Zhang Antonio de la Torre José Pérez-Martín Joaquín Ariño Ppz enzymes are type-1 related Ser/Thr protein phosphatases that are restricted to fungi. In S. cerevisiae and other fungi, Ppz1 is involved in cation homeostasis and is regulated by two structurally-related inhibitory...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3823: Hurdles to Cardioprotection in the Critically Ill International Journal of Molecular Sciences doi: 10.3390/ijms20153823 Authors: Louise E See Hoe Nicole Bartnikowski Matthew A Wells Jacky Y Suen John F Fraser Cardiovascular disease is the largest contributor to worldwide mortality, and the deleterious impact of heart failure (HF) is projected to grow exponentially in the future. As heart transplantation (HTx) is the only effective treatment for...
Mon Aug 05, 2019 03:00
IJMS, Vol. 20, Pages 3816: Supercritical Fluid Extract of Angelica sinensis and Zingiber officinale Roscoe Ameliorates TNBS-Induced Colitis in Rats International Journal of Molecular Sciences doi: 10.3390/ijms20153816 Authors: Jia Liu Ling Yu Nuolan Mo Hai Lan Yan Zhang Xin Liu Qing Wu Inflammatory bowel disease (IBD) is a worldwide healthcare problem calling for the development of new therapeutic drugs. Angelica sinensis and Zingiber officinale Roscoe are two common...
Mon Aug 05, 2019 03:00
JCM, Vol. 8, Pages 1176: Electrical Impedance Tomography for Cardio-Pulmonary Monitoring Journal of Clinical Medicine doi: 10.3390/jcm8081176 Authors: Christian Putensen Benjamin Hentze Stefan Muenster Thomas Muders Electrical impedance tomography (EIT) is a bedside monitoring tool that noninvasively visualizes local ventilation and arguably lung perfusion distribution. This article reviews and discusses both methodological and clinical aspects of thoracic EIT. Initially, investigators...
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JCM, Vol. 8, Pages 1174: A Mutation in ZNF143 as a Novel Candidate Gene for Endothelial Corneal Dysplasia Journal of Clinical Medicine doi: 10.3390/jcm8081174 Authors: Kim You Park Kim Chae Park Jekarl Kim Kwon Choi Kim Paek Lee Kim Park Kim Joo Jung Chung Mok Kim Corneal dystrophies (CDs) are a diverse group of inherited disorders with a heterogeneous genetic background. Here, we report the identification...
Tue Aug 06, 2019 03:00
JCM, Vol. 8, Pages 1175: Approach to the Adult Acute Lymphoblastic Leukemia Patient Journal of Clinical Medicine doi: 10.3390/jcm8081175 Authors: Valentina Sas Vlad Moisoiu Patric Teodorescu Sebastian Tranca Laura Pop Sabina Iluta Sergiu Pasca Cristina Blag Sorin Man Andrei Roman Catalin Constantinescu Ioana Rus Mihail Buse Bogdan Fetica Mirela Marian Cristina Selicean Ioana Berindan-Neagoe Bobe Petrushev Horia Bumbea Alina Tanase Mihnea...
Tue Aug 06, 2019 03:00
JCM, Vol. 8, Pages 1173: New Era of Endoscopic Ultrasound-Guided Tissue Acquisition: Next-Generation Sequencing by Endoscopic Ultrasound-Guided Sampling for Pancreatic Cancer Journal of Clinical Medicine doi: 10.3390/jcm8081173 Authors: Imaoka Sasaki Hashimoto Watanabe Ikeda Pancreatic cancer is a lethal cancer with an increasing incidence. Despite improvements in chemotherapy, patients with pancreatic cancer continue to face poor prognoses. Endoscopic ultrasound-guided...
Mon Aug 05, 2019 03:00
JCM, Vol. 8, Pages 1172: Aortic Valve Sclerosis Adds to Prediction of Short-Term Mortality in Patients with Documented Coronary Atherosclerosis Journal of Clinical Medicine doi: 10.3390/jcm8081172 Authors: Paolo Poggio Laura Cavallotti Veronika A. Myasoedova Alice Bonomi Paola Songia Paola Gripari Vincenza Valerio Mauro Amato Simone Barbieri Pompilio Faggiano Francesco Alamanni Fabrizio Veglia Mauro Pepi Elena Tremoli Damiano Baldassarre Aims:...
Mon Aug 05, 2019 03:00
JCM, Vol. 8, Pages 1171: The Combination of Patient-Reported Clinical Symptoms and an Endoscopic Score Correlates Well with Health-Related Quality of Life in Patients with Ulcerative Colitis Journal of Clinical Medicine doi: 10.3390/jcm8081171 Authors: Satimai Aniwan David H. Bruining Sang Hyoung Park Badr Al-Bawardy Sunanda V. Kane Nayantara Coelho Prabhu John B. Kisiel Laura E. Raffals Konstantinos A. Papadakis Darrell S. Pardi William J. Tremaine Edward...
Mon Aug 05, 2019 03:00
Medical Sciences, Vol. 7, Pages 86: Origins and Impact of Psychological Traits in Polycystic Ovary Syndrome Medical Sciences doi: 10.3390/medsci7080086 Authors: Elisabet Stener-Victorin Maria Manti Romina Fornes Sanjiv Risal Haojiang Lu Anna Benrick Women with polycystic ovary syndrome (PCOS) exhibit compromised psychiatric health. Independent of obesity, women with PCOS are more susceptible to have anxiety and depression diagnoses and other neuropsychiatric disorders....
Mon Aug 05, 2019 03:00
Medicina, Vol. 55, Pages 444: Handedness, Grip Strength, and Memory Function: Considerations by Biological Sex Medicina doi: 10.3390/medicina55080444 Authors: Loprinzi Franklin Farris Ryu Background and Objective: The objective of this study was to evaluate the potential independent and interactive effects of handedness and grip strength on episodic memory function, and whether biological sex moderated these relationships. Materials and Methods: 162 young adults (Mage =...
Tue Aug 06, 2019 03:00
Medicina, Vol. 55, Pages 443: Choice of Methodology Impacts Outcome in Indirect Comparisons of Drugs for Idiopathic Pulmonary Fibrosis Medicina doi: 10.3390/medicina55080443 Authors: David A. Scott Emma Loveman Jill L. Colquitt Katherine O’Reilly Background and Objectives: Idiopathic pulmonary fibrosis (IPF) is a chronic condition leading to lung damage and deterioration in lung function. Following the availability of two new drugs, nintedanib and pirfenidone, a number of network...
Tue Aug 06, 2019 03:00
Medicina, Vol. 55, Pages 442: Umbilical Venous Catheters and Peripherally Inserted Central Catheters: Are They Equally Safe in VLBW Infants? A Non-Randomized Single Center Study Medicina doi: 10.3390/medicina55080442 Authors: Aikaterini Konstantinidi Rozeta Sokou Polytimi Panagiotounakou Maria Lampridou Stavroula Parastatidou Katerina Tsantila Eleni Gounari Antonios K. Gounaris Background and Objective: Peripherally inserted central catheters (PICC) and umbilical...
Tue Aug 06, 2019 03:00
Medicina, Vol. 55, Pages 441: Correlation between Thiopurine S-Methyltransferase Genotype and Adverse Events in Inflammatory Bowel Disease Patients Medicina doi: 10.3390/medicina55080441 Authors: Ribaldone Adriani Caviglia Nicolò Agnesod Simiele Riganò Pellicano Canaparo Perri D’Avolio Luzza Saracco Astegiano Background and Objectives: In patients with inflammatory bowel diseases (IBD), the use of azathioprine results in adverse events...
Mon Aug 05, 2019 03:00
Medicina, Vol. 55, Pages 440: Computer- and Robot-Assisted Therapies to Aid Social and Intellectual Functioning of Children with Autism Spectrum Disorder Medicina doi: 10.3390/medicina55080440 Authors: Joan DiPietro Arpad Kelemen Yulan Liang Cecilia Sik-Lanyi Background and objectives: Children with autism spectrum disorder (ASD) experience challenges with social interactions, a core feature of the disorder. Social skills therapy has been shown to be helpful. Over the past several...
Mon Aug 05, 2019 03:00
Medicina, Vol. 55, Pages 439: A Systematic Review of the Genotoxicity and Antigenotoxicity of Biologically Synthesized Metallic Nanomaterials: Are Green Nanoparticles Safe Enough for Clinical Marketing? Medicina doi: 10.3390/medicina55080439 Authors: Hamed Barabadi Masoud Najafi Hadi Samadian Asaad Azarnezhad Hossein Vahidi Mohammad Ali Mahjoub Mahbobeh Koohiyan Amirhossein Ahmadi Background and objectives: Although studies have elucidated the significant biomedical...
Mon Aug 05, 2019 03:00
Medicines, Vol. 6, Pages 86: A Visualization Tool for Cryo-EM Protein Validation with an Unsupervised Machine Learning Model in Chimera Platform Medicines doi: 10.3390/medicines6030086 Authors: Lin Chen Brandon Baker Eduardo Santos Michell Sheep Darius Daftarian Background: Cryo-electron microscopy (cryo-EM) has become a major technique for protein structure determination. However, due to the low quality of cryo-EM density maps, many protein structures derived from cryo-EM...
Tue Aug 06, 2019 03:00
Medicines, Vol. 6, Pages 85: A Short Review of Iron Metabolism and Pathophysiology of Iron Disorders
Medicines, Vol. 6, Pages 85: A Short Review of Iron Metabolism and Pathophysiology of Iron Disorders Medicines doi: 10.3390/medicines6030085 Authors: Andronicos Yiannikourides Gladys Latunde-Dada Iron is a vital trace element for humans, as it plays a crucial role in oxygen transport, oxidative metabolism, cellular proliferation, and many catalytic reactions. To be beneficial, the amount of iron in the human body needs to be maintained within the ideal range. Iron metabolism is one...
Mon Aug 05, 2019 03:00
Membranes, Vol. 9, Pages 97: Exploring Submerged Forward Osmosis for Water Recovery and Pre-Concentration of Wastewater Before Anaerobic Digestion: A Pilot Scale Study Membranes doi: 10.3390/membranes9080097 Authors: Ferrari Pijuan Rodriguez-Roda Blandin Applying forward osmosis directly on raw municipal wastewater is of high interest for the simultaneous production of a high quality permeate for water reuse and pre-concentrating wastewater for anaerobic digestion. This...
Mon Aug 05, 2019 03:00
Membranes, Vol. 9, Pages 96: Antifouling Properties of Silver-Zinc Oxide Polyamide Thin Film Composite Membrane and Rejection of 2-Chlorophenol and 2,4-Dichlorophenol Membranes doi: 10.3390/membranes9080096 Authors: Kate Kotlhao Isiaka A. Lawal Richard M. Moutloali Michael J. Klink The silver-zinc oxide (Ag-ZnO) polyamide thin film composite (PA-TFC) membrane was prepared by interfacial polymerization. The Ag-ZnO/PA-TFC membrane was characterized by attenuated total reflectance...
Mon Aug 05, 2019 03:00
Metabolites, Vol. 9, Pages 163: The Biosynthetic Pathway of Major Avenanthramides in Oat Metabolites doi: 10.3390/metabo9080163 Authors: Zhiyong Li Yi Chen Dauenpen Meesapyodsuk Xiao Qiu Avenanthramides are a group of N-cinnamoylanthranilic acids, with health-promoting properties mainly found in oat (Avena sativa L.). However, the biosynthetic mechanism for the main three types of avenanthramides (Avn-A, Avn-B and Avn-C) is not completely understood. In the present study, we...
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MPs, Vol. 2, Pages 67: Process Intensification for the Synthesis of 6-Allyl-6-azabicyclo[3.1.0]hex-3-en-2-ol from 1-Allylpyridinium Salt Using a Continuous UV-Light Photoflow Approach Methods and Protocols doi: 10.3390/mps2030067 Authors: Milene A. G. Fortunato Chi-Phong Ly Filipa Siopa Carlos A. M. Afonso A new home-made UV photochemical reactor (95 cm of irradiation zone) consisting of a 12 parallel quartz tubes flow reactor, PQT6 (95 cm under irradiation and an internal diameter...
Mon Aug 05, 2019 03:00
Microorganisms, Vol. 7, Pages 242: Revision of the Lichen Genus Phaeophyscia and Allied Atranorin Absent Taxa (Physciaceae) in South Korea Microorganisms doi: 10.3390/microorganisms7080242 Authors: Dong Liu Jae-Seoun Hur The genus Phaeophyscia Moberg, which belongs to the family Physciaceae, includes about 50 species, with 17 species reported in South Korea. This genus is characterized by a foliose thallus, Physcia/Pachysporaria-type ascospores, a paraplectenchymatous-type lower cortex,...
Tue Aug 06, 2019 03:00
Microorganisms, Vol. 7, Pages 241: Characterization of Salinivibrio socompensis sp. nov., A New Halophilic Bacterium Isolated from the High-Altitude Hypersaline Lake Socompa, Argentina Microorganisms doi: 10.3390/microorganisms7080241 Authors: Cristina Galisteo Cristina Sánchez-Porro Rafael R. de la Haba Clara López-Hermoso Ana B. Fernández María E. Farias Antonio Ventosa The genus Salinivibrio belongs to the family Vibrionaceae and includes Gram-stain-negative, motile...
Mon Aug 05, 2019 03:00
Microorganisms, Vol. 7, Pages 240: Morphology, Ultrastructure, and Mitochondrial Genome of the Marine Non-Photosynthetic Bicosoecid Cafileria marina Gen. et sp. nov. Microorganisms doi: 10.3390/microorganisms7080240 Authors: Dagmar Jirsová Zoltán Füssy Jitka Richtová Ansgar Gruber Miroslav Oborník In this paper, we describe a novel bacteriophagous biflagellate, Cafileria marina with two smooth flagellae, isolated from material collected from a rock surface in the Kvernesfjorden...
Mon Aug 05, 2019 03:00
Microorganisms, Vol. 7, Pages 239: 5-methyl Furfural Reduces the Production of Malodors by Inhibiting Sodium l-lactate Fermentation of Staphylococcus epidermidis: Implication for Deodorants Targeting the Fermenting Skin Microbiome Microorganisms doi: 10.3390/microorganisms7080239 Authors: Manish Kumar Binderiya Myagmardoloonjin Sunita Keshari Indira Putri Negari Chun-Ming Huang Staphylococcus epidermidis (S. epidermidis) is a common bacterial colonizer on the surface of human...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2858: Introduction to “Intramolecular Hydrogen Bonding 2018” Molecules doi: 10.3390/molecules24162858 Authors: Goar Sánchez Non-covalent interactions have attracted the scientific attention during last decades as observed by the numerous studies in the literature [...]
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Molecules, Vol. 24, Pages 2857: Hydrogen Sulfide: Recent Progression and Perspectives for the Treatment of Diabetic Nephropathy Molecules doi: 10.3390/molecules24152857 Authors: Sun Wu Cao Zhu Liu Guo Lin Nie Bian Diabetic kidney disease develops in approximately 40% of diabetic patients and is a major cause of chronic kidney diseases (CKD) and end stage kidney disease (ESKD) worldwide. Hydrogen sulfide (H2S), the third gasotransmitter after nitric oxide...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2856: Differences in the Moisture Capacity and Thermal Stability of Tremella fuciformis Polysaccharides Obtained by Various Drying Processes Molecules doi: 10.3390/molecules24152856 Authors: Chun-Ping Lin Shu-Yao Tsai We compared the proportions and differences in the polysaccharides of Tremella fuciformis (Berkeley) after drying them by various processes, such as 18 °C cold air, 50 °C hot air, and freeze-drying. We also focused on the moisture...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2854: X-Ray Crystal Structures and Organogelator Properties of (R)-9-Hydroxystearic Acid Molecules doi: 10.3390/molecules24152854 Authors: Fioretta Asaro Carla Boga Nicola Demitri Rita De Zorzi Sara Drioli Lara Gigli Gabriele Micheletti Patrizia Nitti Ennio Zangrando (R)-9-hydroxystearic acid, (R)-9-HSA, is a chiral nonracemic hydroxyacid of natural origin possessing interesting properties as an antiproliferative agent against different...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2855: Insights into the Phytochemistry of the Cuban Endemic Medicinal Plant Phyllanthus orbicularis: Fideloside, a Novel Bioactive 8-C-glycosyl 2,3-Dihydroflavonol Molecules doi: 10.3390/molecules24152855 Authors: Antonio Francioso Katrin Franke Claudio Villani Luciana Mosca Maria D’Erme Stefan Frischbutter Wolfgang Brandt Angel Sanchez-Lamar Ludger Wessjohann Phyllanthus orbicularis (Phyllanthaceae) is an endemic evergreen tropical plant...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2853: Effects of Lipid Solid Mass Fraction and Non-Lipid Solids on Crystallization Behaviors of Model Fats under High Pressure Molecules doi: 10.3390/molecules24152853 Authors: Musfirah Zulkurnain V.M. Balasubramaniam Farnaz Maleky Different fractions of fully hydrogenated soybean oil (FHSBO) in soybean oil (10–30% w/w) and the addition of 1% salt (sodium chloride) were used to investigate the effect of high-pressure treatments (HP) on the crystallization...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2851: Rapid Identification of Rainbow Trout Adulteration in Atlantic Salmon by Raman Spectroscopy Combined with Machine Learning Molecules doi: 10.3390/molecules24152851 Authors: Zeling Chen Ting Wu Cheng Xiang Xiaoyan Xu Xingguo Tian This study intends to evaluate the utilization potential of the combined Raman spectroscopy and machine learning approach to quickly identify the rainbow trout adulteration in Atlantic salmon. The adulterated samples...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2852: Special Issue “Raman Spectroscopy: A Spectroscopic ‘Swiss-Army Knife’” Molecules doi: 10.3390/molecules24152852 Authors: Keith C. Gordon This special issue highlights the astonishingly wide range of scientific studies that use Raman spectroscopy to provide insight [...]
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2849: Theoretical Analysis of Efficiency of Multi-Layer Core-Shell Stationary Phases in the High Performance Liquid Chromatography of Large Biomolecules Molecules doi: 10.3390/molecules24152849 Authors: Szabolcs Horváth Fabrice Gritti Róbert Kormány Krisztián Horváth Modern analytical applications of liquid chromatography require columns with higher and higher efficiencies. In this work, the general rate model (GRM) of chromatography is used for the...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2850: Lignan Glycosides from Urena lobata Molecules doi: 10.3390/molecules24152850 Authors: Yuan Luo Cong Su Ning Ding Bowen Qi Fangfang Jia Xiping Xu Xiao Liu Juan Wang Xiaohui Wang Pengfei Tu Shepo Shi Four new lignan glycosides; urenalignosides A–D (1–4), along with 12 known ones (5–16) were isolated from Urena lobata. Their structures were determined on the basis of extensive spectroscopic and spectrometric...
Tue Aug 06, 2019 03:00
Molecules, Vol. 24, Pages 2848: Toxicokinetic Study of a Gastroprotective Dose of Capsaicin by HPLC-FLD Method Molecules doi: 10.3390/molecules24152848 Authors: Mónika Kuzma Krisztina Fodor Attila Almási Gyula Mózsik Tibor Past Pál Perjési Background: A low dose of capsaicin and its natural homologs and analogs (capsaicinoids) have shown to prevent development of gastric mucosal damage of alcohol and non-steroid anti-inflammatory drugs. Based on this experimental observation,...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2846: Quantitative Structure–Activity Relationship Study of Bitter Di-, Tri- and Tetrapeptides Using Integrated Descriptors Molecules doi: 10.3390/molecules24152846 Authors: Xu Chung New quantitative structure–activity relationship (QSAR) models for bitter peptides were built with integrated amino acid descriptors. Datasets contained 48 dipeptides, 52 tripeptides and 23 tetrapeptides with their reported bitter taste thresholds. Independent variables...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2847: Phytotoxic Effects of Commercial Eucalyptus citriodora, Lavandula angustifolia, and Pinus sylvestris Essential Oils on Weeds, Crops, and Invasive Species Molecules doi: 10.3390/molecules24152847 Authors: Ibáñez Blázquez Background: essential oils are well known for their pharmacological effectiveness as well as their repellent, insecticide, and herbicide activities. The emergence of resistant weeds, due to the overuse of synthetic herbicides, makes...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2845: Evolution of Polyphenols during Syrah Grapes Maceration: Time versus Temperature Effect Molecules doi: 10.3390/molecules24152845 Authors: Chantal Ghanem Patricia Taillandier Ziad Rizk Nancy Nehme Jean Pierre Souchard Youssef El Rayess The effect of maceration time and temperature on the phenolic compounds of Syrah grape musts was studied. Pre-fermentation cold (10 °C) and heat maceration (60, 70 and 80 °C) were applied and...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2841: Proteasome Activation to Combat Proteotoxicity Molecules doi: 10.3390/molecules24152841 Authors: Corey L. Jones Jetze J. Tepe Loss of proteome fidelity leads to the accumulation of non-native protein aggregates and oxidatively damaged species: hallmarks of an aged cell. These misfolded and aggregated species are often found, and suggested to be the culpable party, in numerous neurodegenerative diseases including Huntington’s, Parkinson’s,...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2843: Transepithelial Transport Characteristics of the Cholesterol- Lowing Soybean Peptide, WGAPSL, in Caco-2 Cell Monolayers Molecules doi: 10.3390/molecules24152843 Authors: Huijuan Zhang Yawen Duan Yulin Feng Jing Wang Recent studies have shown that soybean protein and its peptides have cholesterol-lowering activities. However, it is not clear whether these peptides could overcome physiological barriers, such as phase II metabolism in gastrointestinal...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2842: Green Extraction of Phenolic Acids from Artemisia argyi Leaves by Tailor-Made Ternary Deep Eutectic Solvents Molecules doi: 10.3390/molecules24152842 Authors: Li Duan Chenmeng Zhang Chenjing Zhang Zijing Xue Yuguang Zheng Long Guo The Artemisia argyi leaf (AL) has been used as a traditional medicine and food supplement in China and other Asian countries for hundreds of years. Phytochemical studies disclosed that AL contains various bioactive...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2844: Furocoumarin Content of Fennel—Below the Safety Threshold Molecules doi: 10.3390/molecules24152844 Authors: Diána Kerekes Attila Csorba Beáta Gosztola Éva Németh-Zámbori Tivadar Kiss Dezső Csupor Furocoumarins are known for their phototoxic and potential carcinogenic effects. These types of compounds have previously been reported from fennel (Foeniculum vulgare Mill.), a widely used medicinal plant and spice; however, no reliable quantitative...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2840: Non-Isothermal Crystallization Kinetics of Poly(4-Hydroxybutyrate) Biopolymer Molecules doi: 10.3390/molecules24152840 Authors: Ina Keridou Luis J. del Valle Lutz Funk Pau Turon Lourdes Franco Jordi Puiggalí The non-isothermal crystallization of the biodegradable poly(4-hydroxybutyrate) (P4HB) has been studied by means of differential scanning calorimetry (DSC) and polarizing optical microscopy (POM). In the first case, Avrami, Ozawa, Mo,...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2839: Dietary Curcumin Prevented Astrocytosis, Microgliosis, and Apoptosis Caused by Acute and Chronic Exposure to Ozone Molecules doi: 10.3390/molecules24152839 Authors: Sendar Daniel Nery-Flores Mario Alberto Ramírez-Herrera María Luisa Mendoza-Magaña Marina María de Jesús Romero-Prado José de Jesús Ramírez-Vázquez Jacinto Bañuelos-Pineda Hugo Alejandro Espinoza-Gutiérrez Abraham Alberto Ramírez-Mendoza Mariana Chávez Tostado Ozone...
Mon Aug 05, 2019 03:00
Molecules, Vol. 24, Pages 2836: Effect of Alkaline Black Liquor Recycling on Alkali Combined with Ozone Pretreatment of Corn Stalk Molecules doi: 10.3390/molecules24152836 Authors: Xia Zhou Mengya Wang Shuo Fang Xiao Liu Ping Liu In the early stage, the best conditions for alkali-bound ozone pretreatment were studied. But after treatment, the alkaline black liquor was directly discarded due to the large amount of organic matter, resulting in environmental pollution and waste...
Mon Aug 05, 2019 03:00
Nanomaterials, Vol. 9, Pages 1133: Nanostructuration of Thin Metal Films by Pulsed Laser Irradiations: A Review Nanomaterials doi: 10.3390/nano9081133 Authors: Francesco Ruffino Maria Grazia Grimaldi Metal nanostructures are, nowadays, extensively used in applications such as catalysis, electronics, sensing, optoelectronics and others. These applications require the possibility to design and fabricate metal nanostructures directly on functional substrates, with specifically controlled...
Tue Aug 06, 2019 03:00
Nanomaterials, Vol. 9, Pages 1132: New Perspectives on the Electronic and Geometric Structure of Au70S20(PPh3)12 Cluster: Superatomic-Network Core Protected by Novel Au12(µ3-S)10 Staple Motifs Nanomaterials doi: 10.3390/nano9081132 Authors: Zhimei Tian Yangyang Xu Longjiu Cheng In order to increase the understanding of the recently synthesized Au70S20(PPh3)12 cluster, we used the divide and protect concept and superatom network model (SAN) to study the electronic and geometric...
Tue Aug 06, 2019 03:00
Nanomaterials, Vol. 9, Pages 1131: Interaction of Gold Nanorods with Human Dermal Fibroblasts: Cytotoxicity, Cellular Uptake, and Wound Healing Nanomaterials doi: 10.3390/nano9081131 Authors: Nouf N. Mahmoud Lubna M. Al-Kharabsheh Enam A. Khalil Rana Abu-Dahab Herein, the cytotoxicity, cellular uptake and wound healing of human dermal fibroblasts were investigated upon treatment with gold nanorods (GNR) decorated with different ligands. Neutral and cationic poly ethylene glycol...
Tue Aug 06, 2019 03:00
Nanomaterials, Vol. 9, Pages 1129: Morphology, Photocatalytic and Antimicrobial Properties of TiO2 Modified with Mono- and Bimetallic Copper, Platinum and Silver Nanoparticles Nanomaterials doi: 10.3390/nano9081129 Authors: Izabela Wysocka Ewa Kowalska Jacek Ryl Grzegorz Nowaczyk Anna Zielińska-Jurek Noble metal nanoparticles (NMNPs) enhanced TiO2 response and extended its activity under visible light. Photocatalytic activity of TiO2 modified with noble metal nanoparticles...
Tue Aug 06, 2019 03:00
Nanomaterials, Vol. 9, Pages 1130: Synthesis of Fe/Ni Bimetallic Nanoparticles and Application to the Catalytic Removal of Nitrates from Water Nanomaterials doi: 10.3390/nano9081130 Authors: Gunay G. Valiyeva Irene Bavasso Luca Di Palma Sevinj R. Hajiyeva Mahammadali A. Ramazanov Flora V. Hajiyeva This work investigated the effectiveness of zerovalent iron and Fe/Ni bimetallic nanoparticles in the treatment of water polluted by a high concentration of nitrates. Nanoparticle...
Tue Aug 06, 2019 03:00
Nanomaterials, Vol. 9, Pages 1128: Hafnium-Doped Mesoporous Silica as Efficient Lewis Acidic Catalyst for Friedel–Crafts Alkylation Reactions Nanomaterials doi: 10.3390/nano9081128 Authors: Huang Luo Wang The development of an efficient solid catalyst for Friedel–Crafts (FC) reactions is of great importance to organic synthetic chemistry. Herein, we reported the hafnium-doped mesoporous silica catalyst Hf/SBA-15 and its first use for Friedel–Crafts alkylation...
Mon Aug 05, 2019 03:00
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