Related ArticlesSearch for the best site in islet xenotransplantation. Int J Surg. 2019 Aug 02;: Authors: Ekser B, Vagefi PA Abstract It can reasonably be anticipated that, within 5-10 years, islet allotransplantation or pig islet xenotransplantation may be the preferred options for ß-cell replacement therapy. The portal vein/liver is currently the preferred clinical site for free islet transplantation, constituting 90% of clinical islet transplants....
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Related ArticlesTreatment of post-adenotonsillectomy velopharyngeal stenosis with bivalved uvular flaps. Int J Pediatr Otorhinolaryngol. 2019 Jul 23;126:109600 Authors: Abdel-Aziz M, El-Tahan AR, El-Fouly M, Kamel A, Abdel-Wahid A Abstract OBJECTIVE: Velopharyngeal stenosis (VS) is a rare devastating complication of adenotonsillectomy that causes obstructive sleep apnea (OSA). Its treatment is challenging and has a high recurrence rate. The aim of this...
Related ArticlesPositional Therapy is a Valuable Treatment Alternative for Obstructive Sleep Apnea. J Transl Int Med. 2019 Jun;7(2):84-85 Authors: Oksenberg A, Gadoth N PMID: 31380242 [PubMed]
Related ArticlesHigh-Resolution Pulse Oximetry and Titration of a Mandibular Advancement Device for Obstructive Sleep Apnea. Front Neurol. 2019;10:757 Authors: Metz JE, Attarian HP, Harrison MC, Blank JE, Takacs CM, Smith DL, Gozal D Abstract Background: To determine whether utilizing high-resolution pulse oximetry is a viable method for evaluating the successful titration of oral appliances for the treatment of obstructive sleep apnea (OSA) patients....
Related ArticlesSleep Disturbance in Bipolar Disorder: Neuroglia and Circadian Rhythms. Front Psychiatry. 2019;10:501 Authors: Steardo L, de Filippis R, Carbone EA, Segura-Garcia C, Verkhratsky A, De Fazio P Abstract The worldwide prevalence of sleep disorders is approximately 50%, with an even higher occurrence in a psychiatric population. Bipolar disorder (BD) is a severe mental illness characterized by shifts in mood and activity. The BD syndrome...
Related ArticlesREM sleep and sleep apnea are associated with language function in Down syndrome children: An analysis of a community sample. J Formos Med Assoc. 2019 Aug 01;: Authors: Lee NC, Hsu WC, Chang LM, Chen YC, Huang PT, Chien CC, Chien YH, Chen CL, Hwu WL, Lee PL Abstract BACKGROUND: The prevalence rate of obstructive sleep apnea (OSA) in the community Down syndrome (DS) children is not clear. Moreover, the impact of OSA and sleep structure...
Related ArticlesComputational analysis of a flapping uvula on aerodynamics and pharyngeal wall collapsibility in sleep apnea. J Biomech. 2019 Jul 25;: Authors: Wang J, Xi J, Han P, Wongwiset N, Pontius J, Dong H Abstract Studying the airflows and the resultant aerodynamic pressure/force in the pharyngeal airway is critical for understanding the pathophysiology of snoring and sleep apnea. In this work, an experiment-driven computational study was conducted...
Related Articles[Immunological mechanism of tumorigenesis promoted by obstructive sleep apnea hypopnea syndrome]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):609-612 Authors: Chen JN, Liu YL, Lu MZ, Luo ZR, Luo SH, Yuan P, Gao XL PMID: 31378024 [PubMed - in process]
Related Articles[The mechanism of arousal in patients with obstructive sleep apnea-hypopnea syndrome]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):604-608 Authors: Du JX, Wang Y, Cao J, Zhang J, Chen BY, Guo HJ PMID: 31378023 [PubMed - in process]
Related Articles[Diagnosis and treatment of obstructive sleep apnea and endocrine diseases]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):602-604 Authors: Liu HG, Luo M PMID: 31378022 [PubMed - in process]
Related Articles[The effect of hypothalamic-pituitary-thyroid axis hormone levels and depression in obstructive sleep apnea-hypopnea syndrome]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):591-595 Authors: Liang Y, Xu JH, Li WY, Qing Z, Shen H, Wang W Abstract Objective: To explore the change of hypothalamic-pituitary-thyroid axis hormones and it's role in depression in obstructive sleep apnea-hypopnea syndrome. Methods: Seventy-three male OSAHS...
Related Articles[Obstructive sleep apnea and cardiovascular diseases: new insights]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):566-569 Authors: Li QY, Li SQ PMID: 31378017 [PubMed - in process]
Related Articles[Clinical consequences and economic costs of obstructive sleep apnea syndrome]. Zhonghua Jie He He Hu Xi Za Zhi. 2019 Aug 12;42(8):561-563 Authors: Xiao Y PMID: 31378015 [PubMed - in process]
Related ArticlesAdherence to Upper-Airway Stimulation in the Treatment of OSA. Chest. 2018 02;153(2):574-575 Authors: Hofauer B, Steffen A, Knopf A, Hasselbacher K, Heiser C PMID: 29406226 [PubMed - indexed for MEDLINE]
Related ArticlesOral Appliances for the Management of OSA: An Updated Review of the Literature. Chest. 2018 02;153(2):544-553 Authors: Hamoda MM, Kohzuka Y, Almeida FR Abstract Oral appliances (OAs) are becoming increasingly recognized not only as an alternative to but also possibly as an adjunct treatment modality for OSA. Compared with CPAP, the gold standard therapy, OAs are less efficacious but are more accepted and tolerated by patients, which,...
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Related ArticlesChemopreventive role of arabinogalactan against experimentally induced pulmonary carcinogenesis: a study in relation to its initiation phase. Drug Chem Toxicol. 2019 Aug 05;:1-13 Authors: Koul A, Garg S, Mohan V Abstract The aim of the present study is to divulge the chemopreventive potential of arabinogalactan (AG) on benzo(a)pyrene [B(a)P] induced initiation of lung carcinogenesis. AG is one of the naturally occurring bioactive polysaccharides...
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Related ArticlesBiologically synthesized green gold nanoparticles from Siberian ginseng induce growth-inhibitory effect on melanoma cells (B16). Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3297-3305 Authors: Wu F, Zhu J, Li G, Wang J, Veeraraghavan VP, Krishna Mohan S, Zhang Q Abstract Siberian ginseng, perennial herb belongs to Araliaceae family used in traditional medicines to treat hypertension, thrombus, inflammation and cancer. In the present...
Related ArticlesThe diagnostic effect of sequential detection of ADA screening and T-SPOT assay in pleural effusion patients. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3272-3277 Authors: Feng M, Sun F, Wang F, Cao G Abstract Purpose: To evaluate the diagnostic effect of sequential detection of Adenosine deaminase (ADA) screening and T-SPOT assay on tuberculosis (TB) pleurisy in pleural effusion patients. Materials and methods: 248 pleural effusion...
Related ArticlesLong noncoding RNA DLEU1 aggravates osteosarcoma carcinogenesis via regulating the miR-671-5p/DDX5 axis. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3322-3328 Authors: Chen X, Zhang C, Wang X Abstract Long non-coding RNAs (LncRNAs) have been proven to be involved in the progression of osteosarcoma. LncRNA DLEU1 was found to act as an oncogene in various types of cancer. In this study, we aimed to explore the biological functions of...
Related ArticlesMiR-638 suppresses the progression of oral squamous cell carcinoma through wnt/β-catenin pathway by targeting phospholipase D1. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3278-3285 Authors: Tang KL, Tang HY, Du Y, Tian T, Xiong SJ Abstract Objective: The current study aimed to explore the function of miR-638 on the progression of oral squamous cell carcinoma (OSCC) and relevant molecular mechanisms. Methods: Expression profile of...
Related ArticlesMiR-629-3p-induced downregulation of SFTPC promotes cell proliferation and predicts poor survival in lung adenocarcinoma. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3286-3296 Authors: Li B, Meng YQ, Li Z, Yin C, Lin JP, Zhu DJ, Zhang SB Abstract The long-term prognosis of patients with lung cancer remains poor and thus it is imminent to further elucidate the molecular mechanism for the oncogenesis of lung cancer. In this study, we...
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Background The bacterial plant pathogenic Ralstonia species belong to the beta-proteobacteria class and are soil-borne pathogens causing vascular bacterial wilt disease, affecting a wide range of plant hosts. These bacteria form a heterogeneous group considered as a “species complex” gathering three newly defined species. Like many other Gram negative plant pathogens, Ralstonia pathogenicity relies on a type III secretion system, enabling bacteria to secrete/inject a large repertoire of type III...
For over 40 years, hydrothermal vents and the communities that thrive on them have been a source of profound discovery for deep-sea ecologists. These ecosystems are found throughout the world on active plate margins as well as other geologically active features. In addition to their ecologic interest, hydrothermal vent fields are comprised of metallic ores, sparking a nascent industry that aims to mine these metal-rich deposits for their mineral wealth. Here, we provide the first systematic assessment...
Background Xenophysogobio boulengeri and X. nudicorpa are the only two species within the genus Xenophysogobio (Cyprinidae, Cypriniformes), and both are endemic to the upper reaches of the Yangtze River. In recent years, due to human activities, the natural resources available to both species have declined sharply. Sympatric species with overlapping niches inevitably compete for their habitats, and genetic structure and diversity can reflect population history and their potential for adaptation...
We used molecular data to assess the degree of genetic divergence across the breeding range of the orange-crowned warbler (Oreothlypis celata) in western North America with particular focus on characterizing the divergence between O. celata populations on the mainland of southern California and on the Channel Islands. We obtained sequences of the mitochondrial gene ND2 and genotypes at ten microsatellite data for 192 O. celata from populations spanning all four recognized subspecies. We recovered...
The brine shrimp genus Artemia Leach (Crustacea, Branchiopoda), a keystone group in hipersaline wetlands all over the world, offers an excellent model to study species interactions (parasitism) and to explore “hidden fauna” (avian endoparasites). The present study is the first report on the parasite infection of the South American species Artemia persimilis from the Southern Chilean Patagonia (50°S–53°S). Samples were collected in Los Cisnes and Amarga lagoons, the two most austral populations of...
Orangutan pelves commonly exhibit a large, projecting tubercle in the iliopubic region, historically assumed to homologous to the pubic tubercle in humans. However, it is not clear whether this tubercle is a unique feature of Pongo, or if it is anatomically homologous with the human pubic tubercle when considered as a soft tissue attachment point. To clarify this issue, we dissected orangutan and other ape cadaveric specimens to evaluate the pelvic brim soft tissues and how they may relate to the...
Background MicroRNA (miRNA) regulates cellular processes by acting on specific target genes, and cellular processes proceed through multiple interactions often organized into pathways among genes and gene products. Hundreds of miRNAs and their target genes have been identified, as are many miRNA-disease associations. These, together with huge amounts of data on gene annotation, biological pathways, and protein–protein interactions are available in public databases. Here, using such data we built...
It is an important issue whether microorganisms can live harmoniously with normal cells in the cardiovascular system. The answer to the question will have enormous impact on medical microbiology. To address the issue, it is essential to identify and characterize the bloodborne microbes in an efficient and comprehensive manner. Due to microbial sequence complexity and the composition of significant number of unknown microbial species in the circulatory system, traditional approaches using cell culture,...
Background In the United States, an estimated 14,748 wastewater treatment plants (WWTPs) provide wastewater collection, treatment, and disposal service to more than 230 million people. The quality of treated wastewater is often assessed by the presence or absence of fecal indicator bacteria. UV disinfection of wastewater is a common final treatment step used by many wastewater treatment plants in order to reduce fecal coliform bacteria and other pathogens; however, its potential...
Background Road traffic accidents are one of the serious disasters that cause public injury, fatality and great economic loss. They are a growing public health problem around the world. Objectives The aim of this study was to determine epidemiological characteristics, tendency and possible influencing factors of road traffic injuries (RTIs) in China, so as to give target suggestions on preventative measures. ...
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Abstract The applicant Dow AgroSciences submitted a request to the competent national authority in France to evaluate the confirmatory data that were identified for oryzalin in the framework of the maximum residue level (MRL) review under Article 12 of Regulation (EC) No 396/2005 as not available. To address the data gaps identified, residue trials on apples were submitted which are appropriate to conclude on the residue situation in kiwi fruits; furthermore, new residue trials on asparagus and...
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Purpose of review With the emergence of the microbiota as a potential driver of host inflammation, the role of iIgA is becoming increasingly important. This review discusses the current evidence regarding the effects of clinical IgA deficiency on the microbiota, and the possible role of microbial dysbiosis in driving inflammation in PID patients. Recent findings The gut microbiota has been investigated in selective IgA deficiency and common variable immunodeficiency, revealing an important...
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Abstract Individuals with alcohol use disorder (AUD) are aware of the risks of alcohol abuse yet continue risky drinking. Research indicates that dysfunctional decision processes and trait variables such as impulsivity contribute to this awareness‐behavior discrepancy. The present study focused on decision‐related versus feedback‐related processes as potential contributors to decision making in AUD by examining the relationship between decision choices and decision‐ and feedback‐related ERP phenomena...
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Abstract Large genetic variations in starvation tolerance in animals indicate that there are multiple strategies to cope with low‐nutrient conditions. Fruit flies (Drosophila melanogaster) typically respond to starvation by suppressing sleep and enhancing locomotor activity presumably to search for food. However, we hypothesized that in a natural population, there are costs and benefits to sleep suppression under low‐nutrient conditions and that conserving energy through sleep could be a better...
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Abstract Introduction Hepatic steatosis is a relatively common incidental finding on computed tomography (CT) studies performed for patients in the emergency department (ED). The aim of our survey was to explore the preferences and perspectives of emergency physicians regarding reporting of incidental findings with a focus on hepatic steatosis. Methods A prospective web‐based questionnaire was conducted and distributed electronically to emergency clinicians with anonymous collection of...
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Abstract Purpose of Review Trichomonas vaginalis is the most prevalent sexually transmitted parasite in the USA; resistant infection is emerging. New drug therapies and dosing regimens of standard therapies are being studied to treat resistant infection. Recent Findings Diagnosis of trichomoniasis has become more sensitive, specific, and widely...
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Abstract Objectives Osteoarthritis (OA) generally increases with age, but it is a complex, multifactorial disease. This study investigated whether obesity, physical activity, and antemortem trauma preclude the use of OA for skeletal age estimation. Materials and Methods The temporomandibular joint (TMJ) and all appendicular joints were scored for skeletal indicators of OA in 408 modern European‐Americans (Bass Collection, TN). Binomial generalized linear models (GLMs) assessed the contributions...
Abstract Objectives Topographic estimates of dental relief are now commonly used to make dietary inferences from the teeth of extant and extinct primates. We thoroughly compared commonly used relief estimates in an effort to help researchers decide which variable best suits their objectives. Materials and methods We combined a total of three datasets: five theoretical models built to compare the effect of tooth complexity and basin depth on relief estimates, a dataset of 110 lower molars...
Abstract Introduction Along the Mesoamerican western margin, the Zacapu basin has yielded a large number of human remains demonstrating usage of artificial cranial modification (ACM). However, at the onset of the Middle Postclassic (1200–1400 AD) only few individuals still exhibit clear signs of ACM. Some authors have suggested that, rather than disappearing entirely, ACM may have become less visible anatomically, making it difficult to identify based on simple visual analyses. Here, we used...
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Abstract Introduction Alopecia areata (AA) is a non‐scarring alopecia which often carries a major impact on patients' quality of life. There is currently no single approved treatment that effectively induces permanent remission. Recently, the JAK‐STAT signaling pathway has emerged as a possible therapeutic target leading to increased interest in the use of JAK inhibitors (JAKis) in the treatment of this pathology. Objectives This review of the literature summarizes information on patients...
Abstract Lasers and other light sources are popular treatment options for facial rejuvenation in recent years. In this study, we aimed to compare the efficacy and safety of fractional radiofrequency (RF) and fractional Erbium :YAG (Er:YAG) laser for facial and neck skin wrinkles, objectively. Three hundred and thirty‐three patients treated with fractional RF and fractional Er:YAG laser were evaluated by two blinded dermatologists. Fractional Er:YAG laser was more effective for the periorbital area;...
Subcutaneous Methotrexate versus oral form for treatment and prophylaxis of chronic plaque Psoriasis
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Background. Placental soluble fms-like tyrosine kinase-1 (sFlt-1), an antagonist of vascular endothelial growth factor, is considered an etiological factor of endothelial damage in pregnancy pathologies. An increase in the sFlt-1 level is associated with alterations of endothelial integrity. In contrast, vitamin D exerts a protective effect and low concentrations of 25(OH)D may have an adverse effect on common complications of pregnancy, such as gestational hypertension (GH), preeclampsia (PE), and...
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Objectives: Previous findings of longitudinal cohort studies indicate that acceleration in age-related hearing decline may occur. Five-year follow-up data of the Netherlands Longitudinal Study on Hearing (NL-SH) showed that around the age of 50 years, the decline in speech recognition in noise accelerates compared with the change in hearing in younger participants. Other longitudinal studies confirm an accelerated loss in speech recognition in noise but mostly use older age groups as a reference....
Objectives: Lexical tone information provides redundant cues for the recognition of Mandarin sentences in listeners with normal hearing in quiet conditions. The contribution of lexical tones to Mandarin sentence recognition in listeners with hearing aids (HAs) is unclear. This study aimed to remove lexical tone information and examine the effects on Mandarin sentence intelligibility in HA users. The second objective was to investigate the contribution of cognitive abilities (i.e., general cognitive...
Objectives: To compare contralateral to ipsilateral stimulation with percutaneous and transcutaneous bone conduction implants. Background: Bone conduction implants (BCIs) effectively treat conductive and mixed hearing losses. In some cases, such as in single-sided deafness, the BCI is implanted contralateral to the remaining healthy ear in an attempt to restore some of the benefits provided by binaural hearing. While the benefit of contralateral stimulation has been shown in at least some...
Objectives: Cochlear reflectance (CR) is the cochlear contribution to ear-canal reflectance. CR is a type of otoacoustic emission that is calculated as a transfer function between forward pressure and reflected pressure. The purpose of this study was to assess effects of age on CR in adults and interactions among age, sex, and hearing loss. Design: Data were collected from 60 adults selected for their age (e.g., 20–29, 30–39, 40–49, 50–59, 60–69, 70–79 years) and normal middle ear status....
Objectives: Understanding the determinants of hearing aid use is important to improve the provision of hearing healthcare. Prior research has indicated that materials in the clinic and online, as well as audiologists’ language during appointments, require a higher literacy level than most patients possess. We hypothesized that low health literacy is a barrier to entry in hearing healthcare, and therefore that health literacy would be positively correlated with the probability of hearing aid use. ...
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Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
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