Πέμπτη 15 Αυγούστου 2019


Multi-View Learning-Based Data Proliferator for Boosting Classification Using Highly Imbalanced Classes
Publication date: Available online 14 August 2019Source: Journal of Neuroscience MethodsAuthor(s): Olfa Graa, Islem RekikAbstractBackground:Multi-view data representation learning explores the relationship between the views and provides rich complementary information that can improve computer-aided diagnosis. Specifically, existing machine learning methods devised to automate neurological disorder diagnosis using brain data provided new insights into how a particular disorder such as autism spectrum...
Journal of Neuroscience Methods
18h
A Dynamic and Self-adaptive Classification Algorithm for Motor Imagery EEG Signals
Publication date: Available online 14 August 2019Source: Journal of Neuroscience MethodsAuthor(s): Kais Belwafi, Sofien Gannouni, Hatim Aboalsamh, Hassan Mathkour, Abdelfattah BelghithAbstractBackground: Brain-computer interface (BCI) is a communication pathway applied for pathological analysis or functional substitution. BCI based on functional substitution enables the recognition of a subject's intention to control devices such as prosthesis and wheelchairs. Discrimination of electroencephalography...
Journal of Neuroscience Methods
18h
Optimisation of Bioimpedance Measurements of Neuronal Activity with an <em>ex vivo</em> Preparation of <em>Cancer pagurus</em> Peripheral Nerves
Publication date: Available online 13 August 2019Source: Journal of Neuroscience MethodsAuthor(s): Christopher A.R. Chapman, Trevor M. Smith, Max Kelly, James Avery, Theo Rouanet, Kirill Aristovich, Daniel J. Chew, David S. HolderAbstractBackgroundIn mammals, fast neural Electrical Impedance Tomography (EIT) can image the myelinated component of the compound action potentials (CAP) using a nerve cuff. If applied to unmyelinated fibres this has great potential to improve selective neuromodulation...
Journal of Neuroscience Methods
1d
Extensive aplasia cutis congenita associated with cephalocranial disproportion and brain extrusion
Abstract Aplasia cutis congenita (ACC) is a rare congenital disorder which can be linked with a variety of other abnormalities. However, the association of this anomaly with cephalocranial disproportion and brain extrusion is rarely reported. In this report, we present a neonate with an extensive ACC with exposed dura mater and sagittal sinus, who later presented with brain extrusion from the defect and an acrocephalic-like feature required decompressive surgery during the first...
Latest Results for Child's Nervous System
16h
Spontaneous resolution of syringomyelia secondary to cranio-cervical junction stenosis in a patient with achondroplasia
Latest Results for Child's Nervous System
16h
GAPO syndrome with craniosynostosis and intracranial hypertension
Abstract Background GAPO (growth retardation, alopecia, pseudoanodontia, and optic atrophy) as a rare genetic disorder includes growth retardation, alopecia, pseudoanodontia, and optic atrophy. It was reported to be associated with craniosynostosis and intracranial hypertension. Case Report A patient with such a rare disorder associated with...
Latest Results for Child's Nervous System
16h
Correction to: Extensive aplasia cutis congenita associated with cephalocranial disproportion and brain extrusion
The original version of this article unfortunately contained an error. The author apologizes for having communicated a wrong name: “Forbid Torkamand” should be in fact “Farbod Torkamand”. Given in this article is the correct author name.
Latest Results for Child's Nervous System
16h
Craniocerebral disproportion after decompressive craniectomy in infants: The hidden enemy of cranial repair?
Abstract Introduction Cranioplasty aims at restoring the physiological integrity and volume of the skull. Any disproportion between the intracranial content and the volume of the container may favor the occurrence of complications. A classification of volume mismatches is proposed. A negative mismatch, consisting of intracranial content minor to skull volume, is well represented by the sinking flap. On the other side, a positive...
Latest Results for Child's Nervous System
16h
The ventriculo-cholecystic shunt: does CSF volume matter?
Abstract Introduction The management of hydrocephalus in paediatric patients where the peritoneum has failed can be challenging. One option is to perform a ventriculo-cholecystic shunt. However, little is known about the capacity of the gall bladder to accommodate cerebrospinal fluid (CSF). Methods A retrospective case series was performed to...
Latest Results for Child's Nervous System
16h
H3K27M, IDH1, and ATRX expression in pediatric GBM and their clinical and prognostic significance
Abstract Purpose Pediatric glioblastoma (pGBM) tumors have been identified as an entity distinct and different from the adult variety of GBM not only with respect to pathogenesis, genetics, and molecular alterations but also in clinical outcomes and overall survival. This study aims to evaluate the immunohistochemical profile of molecular markers in pediatric GBM and correlate them with clinical features and prognosis. ...
Latest Results for Child's Nervous System
16h
The role of spinal angiography in the evaluation and treatment of pediatric spinal vascular pathology: a case series and systematic review
Abstract Object While it has been extensively studied in adults, the role of spinal angiography in children with suspected spinal vascular malformations is not fully characterized. With special implications regarding technique, radiation dose, and pathology, we sought to review our single-center experience with pediatric spinal vascular pathology and use a systematic review of the literature to further identify its role in pediatrics....
Latest Results for Child's Nervous System
18h
Medulloblastoma and central nervous system germ cell tumors in adults: is pediatric experience applicable?
Abstract Medulloblastoma and central nervous system (CNS) germ cell tumors are very rare in adults, while they account for 25% and 5% of brain tumors in children, respectively (Pastore et al. Eur J Cancer 42:2064–208, 2006). Pediatric experiences, mostly from randomized and controlled clinical trials, have led to different tailored treatments, based on various risk factors, including histology, and extent of disease. For medulloblastoma, biological features have recently emerged...
Latest Results for Child's Nervous System
18h
Tethered cord syndrome with lower back pain and lumbosacral angle increase: case report
Abstract Introduction Tethered cord syndrome (TCS) is the progressive development of various neuromuscular dysfunctions caused by the traction of the conus medullaris resulting from congenital or acquired causes, which are often accompanied by fecal and/or urinary incontinence and abnormal sensory motor functions of lower limbs. Lower back pain is a common clinical symptom of TCS patients and can be significantly improved by surgical untethering....
Latest Results for Child's Nervous System
18h
Graham Fieggen, ISPN president 2017–2018
Latest Results for Child's Nervous System
20h
Primary cavernous sinus germinoma with atypical extension pattern: a case report and review of the literature
Abstract Primary intracranial germinoma is a rare central nervous system tumor that usually arises in the pineal and the supra-sellar region. Here, we report a rare case of primary intracavernous sinus germinoma with an atypical extension pattern, with a comparison to germinomas originating from the cavernous sinus as described in the existing literature. A 12-year-old boy was admitted to our hospital with the chief complaint of the left-side ptosis and double vision. Magnetic...
Latest Results for Child's Nervous System
22h
The growth of the neurocranium: literature review and implications in cranial repair
Abstract Background Postnatal growth of neurocranium is prevalently completed in the first years of life, thus deeply affecting the clinical presentation and surgical management of pediatric neurosurgical conditions involving the skull. This paper aims to review the pertinent literature on the normal growth of neurocranium and critically discuss the surgical implications of this factor in cranial repair. ...
Latest Results for Child's Nervous System
22h
Greenstick fracture-hinge decompressive craniotomy in infants: illustrative case and literature review of techniques for decompressive craniotomy without bone removal
Abstract Purpose We present the potential usefulness of a greenstick fracture-hinge decompressive craniotomy, a variant of a hinge-craniotomy, as an alternative technique for use with a decompressive craniectomy (DC) in infants. A literature review of hinge-craniotomy procedures and technical variants is also provided, with a focus on complications associated with a DC peculiar to infants and children. ...
Latest Results for Child's Nervous System
22h
Malignant PRES and RCVS after brain surgery in the early postpartum period
Publication date: Available online 14 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): G. Cossu, R.T. Daniel, A.F. Hottinger, R. Maduri, M. MessererAbstractThe management of women with brain tumors in the early post-partum period may be demanding as the patho-physiological changes that occur during pregnancy may also manifest in the early post-partum period. The aim of our paper is to report a case of late-onset post-partum pre-eclampsia after brain tumor surgery, complicated by posterior...
Clinical Neurology and Neurosurgery
17h
Case Report of a Partially Thrombosed ACoA aneurysm presenting with Bilateral Foot Drop
Publication date: Available online 14 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Ahmad Sweid, Stavropoula Tjoumakaris, Nabeel Herial, Michael R. Gooch, Robert H. Rosenwasser, Pascal JabbourAbstractBackground and ImportanceFoot drop is defined as a weakness in the ankle and foot dorsiflexors. A disruption of the neural pathway starting from the mesial frontal cortex and ending in the peroneal nerve can lead to foot drop. Unilateral foot drop due to lower motor neuron injury is...
Clinical Neurology and Neurosurgery
17h
Pneumosinus Dilatans: An exploration into the association between Arachnoid Cyst, Meningioma and the pathogenesis of Pneumosinus Dilatans
Publication date: Available online 14 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): James Sweatman, Radu BeltechiAbstractObjectivesTo investigate the association between certain intracranial masses (meningioma and arachnoid cyst) and the incidence of Pneumosinus Dilatans (PSD) – including whether the size of the mass correlates with severity of the condition.Patients and methodsA review of the available case reports on PSD was performed. Clinical data was extracted from 111 case...
Clinical Neurology and Neurosurgery
17h
The influence of preoperative mental health on clinical outcomes after laminectomy in patients with lumbar spinal stenosis
Publication date: Available online 13 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Yoshiomi Kobayashi, Yoji Ogura, Takahiro Kitagawa, Takahiro Tadokoro, Yoshiro Yonezawa, Yohei Takahashi, Akimasa Yasuda, Yoshio Shinozaki, Jun OgawaAbstractObjectiveThe influence of preoperative mental health on health-related quality of life (HRQOL) in patients with lumbar spinal stenosis (LSS) remains unclear. This study aims to investigate the influence of preoperative mental health HRQOL after...
Clinical Neurology and Neurosurgery
1d
Association between tumor location and neurocognitive functioning using tumor localization maps
Abstract Introduction Patients with diffuse glioma often experience neurocognitive impairment already prior to surgery. Pertinent information on whether damage to a specific brain region due to tumor activity results in neurocognitive impairment or not, is relevant in clinical decision-making, and at the same time renders unique information on brain lesion location and functioning relationships. To examine the impact of tumor location...
Neuro-Oncology
19h
Long-term visual acuity outcomes after radiation therapy for sporadic optic pathway glioma
Abstract Purpose Children with sporadic optic pathway glioma (OPG) commonly experience a decline in visual acuity (VA). This study aimed to quantify long-term VA outcomes after definitive radiation therapy (RT). Methods From 1997 to 2017, 41 patients underwent RT for OPG and had baseline VA testing. All patients underwent serial VA testing every 3–6 months...
Neuro-Oncology
20h
Global extracellular vesicle proteomic signature defines U87-MG glioma cell hypoxic status with potential implications for non-invasive diagnostics
Abstract Purpose Glioblastoma multiforme (GBM) is the most common and lethal of primary malignant brain tumors. Hypoxia constitutes a major determining factor for the poor prognosis of high-grade glioma patients, and is known to contribute to the development of treatment resistance. Therefore, new strategies to comprehensively profile and monitor the hypoxic status of gliomas are of high clinical relevance. Here, we have explored how the...
Neuro-Oncology
20h
Classes of dendritic information processing
Publication date: October 2019Source: Current Opinion in Neurobiology, Volume 58Author(s): Alexandre Payeur, Jean-Claude Béïque, Richard NaudDendrites are much more than passive neuronal components. Mounting experimental evidence and decades of computational work have decisively shown that dendrites leverage a host of nonlinear biophysical phenomena and actively participate in sophisticated computations, at the level of the single neuron and at the level of the network. However, a coherent view of...
Current Opinion in Neurobiology
1d
Untargeted metabolomics analysis of rat hippocampus subjected to sleep fragmentation
Publication date: Available online 13 August 2019Source: Brain Research BulletinAuthor(s): Dae Wui Yoon, Hyuk Nam Kwon, Xing Jin, Jin Kwan Kim, Seung Ku Lee, Sunghyouk Park, Chang-Ho Yun, Chol ShinAbstractSleep fragmentation (SF) commonly occurs in several pathologic conditions and is especially associated with impairments of hippocampus-dependent neurocognitive functions. Although the effects of SF on hippocampus in terms of protein or gene levels were examined in several studies, the impact of...
ScienceDirect Publication: Brain Research Bulletin
1d
The role of Locus Coeruleus in neuroinflammation occurring in Alzheimer’s disease
Publication date: Available online 13 August 2019Source: Brain Research BulletinAuthor(s): Filippo Sean Giorgi, Luigi Francesco Saccaro, Alessandro Galgani, Carla Letizia Busceti, Francesca Biagioni, Alessandro Frati, Francesco FornaiAbstractAlzheimer’s Disease (AD) represents the main degenerative dementia. Its neuropathological hallmarks are β-amyloid plaques (APs) and neurofibrillary tangles (NFT), which lead to neuronal loss and brain atrophy. Recent data show that, early in the course of AD,...
ScienceDirect Publication: Brain Research Bulletin
1d
Electroencephalography in Psychiatric Surgery: Past Use and Future Directions
The last two decades have seen a re-emergence of surgery for intractable psychiatric disease, in large part due to increased use of deep brain stimulation. The development of more precise, image-guided, less invasive interventions has improved the safety of these procedures, even though the relative merits of modulation at various targets remain under investigation. With an increase in the number and type of interventions for modulating mood/anxiety circuits, the need for biomarkers to guide surgeries...
American Society for Stereotactic and Functional Neurosurgery
1d
Emotional and Autonomic Processing of Olfactory Stimuli Is Compromised in Patients with a History of Mild Traumatic Brain Injury
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
1h
Opioid Use among Individuals with Traumatic Brain Injury: A Perfect Storm?
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
1h
Neural Correlates of Response Inhibition and Error Processing in Individuals with Mild Traumatic Brain Injury: An Event-Related Potential Study
Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma
1d
Spontaneous Resolution of Syringomyelia with a 16-Year Serial Magnetic Resonance Imaging Follow-Up: A Case Report and Literature Review
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Chenghua Yuan, Qingyu Yao, Can Zhang, Fengzeng JianBackgroundThe natural course of syringomyelia is unpredictable. Only a few cases of adults with spontaneous resolution of syringomyelia associated with Chiari malformation type I (CM-I) have been reported. The timing of surgical intervention for syringomyelia remains controversial. The present report has documented a case with the longest medical history of syringomyelia...
World Neurosurgery
16h
Thrombosed Middle Meningeal Artery Aneurysms Mimicking Aneurysmal Bone Cysts in a Patient with Fibrous Dysplasia
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Shunsuke Yamashita, Hidehito Kimura, Masaaki Kohta, Atsushi Fujita, Eiji KohmuraBackgroundThe aneurysmal bone cyst (ABC) is a rare osteolytic lesion that is often associated with osseous disease such as fibrous dysplasia (FD).Case DescriptionA 66-year-old woman previously diagnosed with FD presented with suddenly reduced visual acuity. Computed tomography and magnetic resonance imaging revealed a large osteolytic lesion...
World Neurosurgery
16h
Case of Recurrent Artery of Heubner Aneurysm Masquerading as Partially Thrombosed A1 Aneurysm Radiologically
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Jolyn Khoo, Boyuan Khoo, Andrew F. Alalade, Jefferson WebsterBackgroundRecurrent artery of Heubner (RAH) aneurysms are rare, with only 7 reported cases in the literature to date. In evaluating cerebral aneurysms, cerebral digital subtraction angiogram (DSA) is considered the gold standard and demonstrated the RAH aneurysms in previous case reports. We present a case of spontaneous subarachnoid hemorrhage secondary to RAH...
World Neurosurgery
16h
Olfactory Results of Endoscopic Endonasal Surgery for Pituitary Adenoma: A Prospective Study of 143 Patients
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): David Netuka, Václav Masopust, Petra Fundová, Jaromír Astl, David Školoudík, Martin Májovský, Vladimír BenešBackgroundClinical examination, including pre- and postoperative assessment of olfaction function, should be included in evaluating surgical outcomes in patients with pituitary adenomas. Most of the studies are lacking assessment of olfactory function.MethodsA prospective study of 143 patients who underwent surgical...
World Neurosurgery
16h
Comparison of Biomechanical Performance Among Posterolateral Fusion and Transforaminal, Extreme, and Oblique Lumbar Interbody Fusion: A Finite Element Analysis
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Teng Lu, Yi LuObjectiveWe compared the biomechanical differences among posterolateral fusion (PLF) and transforaminal, extreme, and oblique lumbar interbody fusion (TLIF, XLIF, and OLIF, respectively) procedures.MethodsAn intact finite element (FE) model of the L3–L5 lumbar spine was constructed. The PLF, TLIF with a banana-shaped cage, TLIF with a straight cage, XLIF, and OLIF procedures were simulated at the L4-L5...
World Neurosurgery
16h
Are Modic Vertebral End-Plate Signal Changes Associated with Degeneration or Clinical Outcomes in the Cervical Spine?
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Xiaoyu Yang, Roland Donk, Mark P. Arts, Carmen L.A. Vleggeert-LankampObjectiveTo report on the incidence of Modic changes (MCs) in patients with cervical radiculopathy due to a herniated disc. Presence of MCs was correlated to clinical outcomes and the presence of radiological degeneration.MethodsPatients that underwent anterior discectomy for a cervical radiculopathy due to a herniating disc were analyzed for the presence...
World Neurosurgery
16h
Central Nervous System Tumors in Uganda: Outcomes of Surgical Treatment and Complications Assessed Through Telephone Survey
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Bina W. Kakusa, Linda W. Xu, Silvia D. Vaca, Juliet Nalwanga, Joel Kiryabwire, Hussein Ssenyonjo, John Mukasa, Michael Muhumuza, Michael M. Haglund, Gerald A. GrantBackgroundUganda has one of the largest unmet neurosurgical needs in the world, but has seen major improvements in neurosurgery—largely centered at Mulago National Referral Hospital (MNRH). This study implements the first long-term follow-up and outcomes analysis...
World Neurosurgery
16h
Virtual Reality-Based Evaluation of Surgical Planning and Outcome of Monosegmental, Unilateral Cervical Foraminal Stenosis
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Samer Zawy Alsofy, Ralf Stroop, Ivo Fusek, Heinz Welzel Saravia, Ioanna Sakellaropoulou, Murat Yavuz, Christian Ewelt, Makoto Nakamura, Thomas FortmannBackgroundForaminal cervical nerve root compression can be caused by lateral disk herniation or osteophyte formation of the vertebrae. Improved diagnosis and evaluation can be achieved using different imaging techniques: radiographs, computed tomography (CT), and magnetic...
World Neurosurgery
16h

Pallidothalamic Tractotomy (Forel's Field H1-tomy) for Dystonia: Preliminary Results
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Shiro Horisawa, Atsushi Fukui, Yukiko Tanaka, Lew Wendong, Hayato Yamahata, Takakazu Kawamata, Takaomi TairaObjectivesThe pallidothalamic tract connects the globus pallidus internus with the ventroanterior and ventrolateral parts of the thalamus. Lesioning or stimulation of the pallidothalamic tract has ameliorating effects on dyskinesia and dystonia in patients with Parkinson disease. However, the effect of the procedure...
World Neurosurgery
16h
Prevention of Thromboembolic Infarction After Surgery for Traumatic Cervical Fracture with Vertebral Artery Occlusion by Preoperative Endovascular Coil Embolization
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Masahiro Indo, Soichi Oya, Masaaki Shojima, Koichi Inokuchi, Tadashi Yahata, Satoru Sugiyama, Toru MatsuiBackgroundVertebral artery injuries (VAIs) caused by cervical trauma include irregularities with narrowing of the arterial wall, dissection, pseudoaneurysm formation, occlusion, and transection. Although recent guidelines have recommended anticoagulant or antiplatelet therapy to prevent subsequent stroke in patients...
World Neurosurgery
16h
Morphologic Parameters and Location Associated with Rupture Status of Intracranial Aneurysms in Elderly Patients
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Muhammad Waqas, Hamidreza Rajabzadeh-Oghaz, Vincent M. Tutino, Kunal Vakharia, Kerry E. Poppenberg, Ashkan Mowla, Hui Meng, Adnan H. SiddiquiBackgroundTreatment of unruptured intracranial aneurysms (IAs) in elderly patients is associated with a high risk of morbidity and mortality, necessitating a thorough understanding of the potential rupture risk. The aim of this study was to identify morphologic parameters and anatomic...
World Neurosurgery
16h
Retrospective Chronologic Computed Tomography Analysis of Bone Flap Fusion and Resorption After Craniotomy and Autologous Cryopreserved Cranioplasty
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Jin Pyeong Jeon, Yunsuk Heo, Suk-Hyung Kang, Jin Seo Yang, Hyuk Jai Choi, Yong-Jun ChoBackgroundIn open brain surgery, fixation of the bone flap is the final procedure. The bone flaps then fuse naturally. The objective of this study was to investigate the chronological process of bone fusion after craniotomy and autologous cranioplasty.MethodsRetrospective data were collected from patients who underwent craniotomy or...
World Neurosurgery
16h
Development of a Novel 3D Printed Phantom for Teaching Neurosurgical Trainees the Freehand Technique of C2 Laminar Screw Placement
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): William Clifton, Eric Nottmeier, Steven Edwards, Aaron Damon, Conrad Dove, Karim Refaey, Mark PichelmannBackground3D printed models have grown in popularity for resident training. Currently there is a paucity of simulators specifically designed for advanced cervical instrumentation. Our institution created a unique simulator for the instruction of freehand placement of C2 laminar screws using a specific 3-dimensional...
World Neurosurgery
16h
Is Gross Total Resection Reasonable in Adults with Craniopharyngiomas with Hypothalamic Involvement?
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Caroline Apra, Ciprian Enachescu, Veronique Lapras, Gerald Raverot, Emmanuel JouanneauObjectiveThe treatment of hypothalamus-invading craniopharyngiomas, based on pediatric experience, is subtotal resection (STR) with radiotherapy. This strategy sometimes leads to uncontrollable tumor progression. In adults, with the use of endoscopic endonasal surgery (EES), does removing the hypothalamic part of the tumor—whenever...
World Neurosurgery
16h
Volume–Cost Relationship in Neurosurgery: Analysis of 12,129,029 Admissions from the National Inpatient Sample
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): James S. Yoon, Oliver Y. Tang, Michael T. LawtonBackground/ObjectiveSeveral studies have documented improved outcomes at high-volume hospitals for neurosurgery. However, the relationship between neurosurgical volume and costs remains poorly understood.MethodsUsing neurosurgery-specific Diagnosis-Related Groups (DRG) codes, we identified adult neurosurgical admissions in the National Inpatient Sample from 2002 to 2014....
World Neurosurgery
16h
Incidence, Outcomes and Predictors of Primary Central Nervous System Melanoma: A SEER-Based Study
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Weitao Man, Guihuai WangIntroductionPrimary central nervous system (pCNS) melanoma is an extremely rare malignant tumor. We explored the incidence, outcomes, and predictors of pCNS melanoma.MethodsWe queried the Surveillance, Epidemiology, and End Results database to identify all patients diagnosed with pCNS melanoma during 1973–2015. Overall survival (OS) was obtained by using the Kaplan-Meier curves. Log-rank test...
World Neurosurgery
16h
Perioperative Complications and Mortality Following Anterior Odontoid Screw Fixation in Elderly Patients: A National Database Analysis
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Michael Longo, Yaroslav Gelfand, Rafael De la Garza Ramos, Murray Echt, Merritt D. Kinon, Vijay Yanamadala, Reza YassariObjectiveTo identify predictors of short-term mortality and complications after anterior odontoid screw fixation.MethodsThis was a retrospective analysis of a national database. The American College of Surgeons National Quality Improvement Database was queried using Current Procedural Terminology codes...
World Neurosurgery
16h
Mixed Reality−Based Preoperative Planning for Training of Percutaneous Transforaminal Endoscopic Discectomy: A Feasibility Study
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Haiyang Yu, Zhi Zhou, Xuefeng Lei, Huaqing Liu, Guoxin Fan, Shisheng HeObjectiveTo explore the effect of preoperative planning using mixed reality (MR) on training of percutaneous transforaminal endoscopic discectomy (PTED).MethodsBefore the training, we invited an experienced chief physician to plan the puncture path of PTED on the X-ray films of the lumbar spine model and the 3D Slicer platform, respectively, and used...
World Neurosurgery
16h
Clinical and Magnetic Resonance Imaging Longitudinal Follow-up of Neuromuscular Choristomas
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Andrés A. Maldonado, Robert J. Spinner, Jodi M. Carter, Jonathan J. Stone, B. Matthew HoweIntroductionThe natural history of growth and radiologic progression of neuromuscular choristomas (NMCs) remain unknown. The purpose of this study was to describe the radiologic growth pattern of NMCs and to determine how the pattern of growth relates to clinical progression.MethodsA retrospective review was performed for patients...
World Neurosurgery
16h
Effect of Institutional Volume on Acoustic Neuroma Surgical Outcomes: State Inpatient Database 2009–2013
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Elhaum Rezaii, Daphne Li, Daniel M. Heiferman, Caroline C. Szujewski, Brendan Martin, Adrienne Cobb, Giselle E.K. Malina, Kurt A. Grahnke, Ryan C. Hofler, John P. Leonetti, Douglas E. AndersonBackgroundEvolving technologies and health care quality metrics have altered treatment algorithms for acoustic neuromas (ANs), increasing trends toward observation and radiosurgery, with proportionate declines in use of microsurgery....
World Neurosurgery
16h
Elevated Lactate Dehydrogenase Level Predicts Postoperative Pneumonia in Patients with Aneurysmal Subarachnoid Hemorrhage
Publication date: September 2019Source: World Neurosurgery, Volume 129Author(s): Chen-Yu Ding, Lei Peng, Yuan-Xiang Lin, Liang-Hong Yu, Deng-Liang Wang, De-Zhi KangBackgroundLactate dehydrogenase (LDH) is a nonspecific inflammatory biomarker and has been reported to be useful in predicting community-acquired pneumonia and Mycoplasma pneumoniae pneumonia. The connection between LDH level and postoperative pneumonia (POP) in patients with aneurysmal subarachnoid hemorrhage (aSAH) is still unclear....
World Neurosurgery
16h
Enhanced Recovery After Surgery (ERAS) for Spine Surgery: A Systematic Review
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Nicholas Dietz, Mayur Sharma, Shawn Adams, Ahmad Alhourani, Beatrice Ugiliweneza, Dengzhi Wang, Miriam Nuño, Doniel Drazin, Maxwell BoakyeBackgroundEnhanced recovery after surgery (ERAS) represents an evidence-based multidisciplinary approach to perioperative management after major surgery that decreases complications and readmissions and improves functional recovery. Spine surgery is a traditionally invasive intervention...
World Neurosurgery
1d
Full-Endoscopic Resection of Ligamentum Flavum Cyst in Lumbar Spine
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Sagar B. Sharma, Guang-Xun Lin, Jin-Sung KimBackgroundCysts of the ligamentum flavum (LF) are rare occurrences, with only a few cases reported in literature. They are a result of age-related degenerative changes in the LF. The cyst compresses the neural elements and causes neurogenic symptoms. Endoscopic resection of the LF cyst has not been described in literature. In this report, we describe our experience with endoscopic...
World Neurosurgery
1d
Depression as a risk factor for impulse control disorders in Parkinson's disease
Abstract Objectives To longitudinally evaluate the role of depression in the development of impulse control disorders (ICD) in Parkinson's disease (PD) patients. Methods Using data from the Parkinson's Progression Markers Initiative (PPMI) we included PD patients without ICD at baseline according to the Questionnaire for Impulsive‐Compulsive Disorders in PD (QUIP). Patients were prospectively evaluated first quarterly and then biannually. Development of ICD was defined as an increase in...
Annals of Neurology
7h
Why “Medicare for All” Would be a Disaster
Annals of Neurology
7h
Issue Information
Annals of Neurology
7h
Annals of Neurology: Volume 86, Number 3, September 2019
A fluorescence photomicrograph showing mitochondria in a human neuroblastoma cell line, SH‐SY5Y. The nuclei of the cells are stained blue with DAPI and the mitochondria are stained gold with a combination of mitotracker red and antibody against ssbp1, a single‐stranded DNA binding protein that is necessary for replication of mitochondrial DNA. Green punctate structures may indicate the presence of mitochondrial nucleoids. Mutations in SSBP1 may result in autosomal dominant optic atrophy with variable...
Annals of Neurology
7h
Improved Assessment of Middle Ear Recurrent Cholesteatomas Using a Fusion of Conventional CT and Non-EPI-DWI MRI [HEAD & NECK]
BACKGROUND AND PURPOSE:Recurrent middle ear cholesteatomas are commonly preoperatively assessed using MR imaging (non-EPI-DWI) and CT. Both modalities are used with the aim of distinguishing scar tissue from cholesteatoma and determining the extent of bone erosions. Inflammation and scar tissue associated with the lesions might hamper a proper delineation of the corresponding extensions on CT images. Using surgical findings as the criterion standard, we assessed the recurrent middle ear cholesteatoma...
Neuroradiology
1d

Defining Ischemic Core in Acute Ischemic Stroke Using CT Perfusion: A Multiparametric Bayesian-Based Model [ADULT BRAIN]
BACKGROUND AND PURPOSE:The Bayesian probabilistic method has shown promising results to offset noise-related variability in perfusion analysis. Using CTP, we aimed to find optimal Bayesian-estimated thresholds based on multiparametric voxel-level models to estimate the ischemic core in patients with acute ischemic stroke.MATERIALS AND METHODS:Patients with anterior circulation acute ischemic stroke who had baseline CTP and achieved successful recanalization were included. In a subset of patients,...
Neuroradiology
1d
Molecular Subtype Classification in Lower-Grade Glioma with Accelerated DTI [FUNCTIONAL]
BACKGROUND AND PURPOSE:Image-based classification of lower-grade glioma molecular subtypes has substantial prognostic value. Diffusion tensor imaging has shown promise in lower-grade glioma subtyping but currently requires lengthy, nonstandard acquisitions. Our goal was to investigate lower-grade glioma classification using a machine learning technique that estimates fractional anisotropy from accelerated diffusion MR imaging scans containing only 3 diffusion-encoding directions.MATERIALS AND METHODS:Patients...
Neuroradiology
1d
Intense and sustained pain reduces cortical responses to auditory stimuli: implications for the interpretation of the effects of Heterotopic Noxious Conditioning Stimulation in humans
Abstract Phasic pain stimuli are inhibited when they are applied concomitantly with a conditioning tonic stimulus at another body location (Heterotopic Noxious Conditioning Stimulation, HNCS). While the effects of HNCS are thought to rely on a spino‐bulbo‐spinal mechanism in animals (termed Diffuse Noxious Inhibitory Controls, DNIC), the underlying neurophysiology in humans may involve other pathways. In this study, we investigated the role of concomitant supraspinal mechanisms during HNCS by presenting...
European Journal of Neuroscience
21h
A sinister subject: Quantifying handedness‐based recruitment biases in current neuroimaging research
Abstract Approximately ten percent of humans are left‐handed or ambidextrous (adextral). It has been suggested that, despite their sizable representation at the whole‐population level, this demographic is largely avoided by researchers within the neuroimaging community. To date, however, no formal effort has been made to quantify the extent to which adextrals are excluded from neuroimaging‐based research. Here we aim to address this question in a review of over 1,000 recent articles published in...
European Journal of Neuroscience
1d
Shift in lateralization during illusory self‐motion: EEG responses to visual flicker at 10 Hz and frequency‐specific modulation by tACS
Abstract Self‐motion perception is a key aspect of higher vestibular processing, suggested to rely upon hemispheric lateralization and alpha‐band oscillations. The first aim of this study was to test for any lateralization in the EEG alpha‐band during the illusory sense of self‐movement (vection) induced by large optic flow stimuli. Visual stimuli flickered at alpha‐frequency (approx. 10 Hz) in order to produce steady state visually evoked potentials (SSVEPs), a robust EEG measure which allows probing...
European Journal of Neuroscience
1d
Assessment of the effect of continuous theta burst stimulation of the motor cortex on manual dexterity in non‐human primates in a direct comparison with invasive intracortical pharmacological inactivation
Continuous theta burst transcranial magnetic stimulation (cTBS) of the primary motor cortex (M1) in macaques induced a modest to moderate, and variable, effect on manual dexterity performance with the contralateral hand, in sharp contrast to a pharmacological inactivation of M1 (intracortical infusion of muscimol), leading to hand paresis, with total incapacity to grasp and pull a drawer. Abstract Non‐invasive reversible perturbation techniques of brain output such as continuous theta burst stimulation...
European Journal of Neuroscience
1d

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου