Proteomics analysis of asthenozoospermia and identification of glucose-6-phosphate isomerase as an important enzyme for sperm motility

Publication date: Available online 5 August 2019Source: Journal of ProteomicsAuthor(s): Yueshuai Guo, Wen Jiang, Weiling Yu, Xin Niu, Fangjuan Liu, Tao Zhou, Hao Zhang, Yan Li, Hui Zhu, Zuomin Zhou, Jiahao Sha, Xuejiang Guo, Daozhen ChenAbstractAsthenozoospermia, in which sperm motility is affected, is one of the primary causes of male infertility. However, the exact mechanism responsible for the defective motility remains unknown. It is important to identify the precise proteins or pathways involved...

ScienceDirect Publication: Journal of Proteomics

16h

The muscular, hepatic and adipose tissues proteomes in muskox (<em>Ovibos moschatus</em>): Differences between males and females

Publication date: Available online 5 August 2019Source: Journal of ProteomicsAuthor(s): D.M. Ribeiro, S. Planchon, C.C. Leclercq, K. Raundrup, S.P. Alves, R.J.B. Bessa, J. Renaut, A.M. AlmeidaAbstractThe muskox (Ovibos moschatus) is a ruminant highly adapted to arctic conditions. The objective of this work is to study liver, muscle and adipose tissues proteomes in muskoxen highlighting sex differences. Ten animals (5 per sex) were sampled in Western Greenland during the winter hunting season. During...

ScienceDirect Publication: Journal of Proteomics

16h

Glycation of glucose sensitive lysine residues K36, K438 and K549 of albumin is associated with prediabetes

Publication date: Available online 5 August 2019Source: Journal of ProteomicsAuthor(s): Rajeshwari Rathore, Babasaheb Sonawane, M.G. Jagadeeshaprasad, Shweta Kahar, B. Santhakumari, A.G. Unnikrishnan, Mahesh J. KulkarniAbstractPrediabetes is a risk factor for the development of diabetes. Early diagnosis of prediabetes may prevent the onset and progression of diabetes and its associated complications. Therefore, this study aimed at identification of novel markers for efficient prediction of prediabetes....

ScienceDirect Publication: Journal of Proteomics

16h

Proteomic analysis revealed the survival strategy of <em>Coxiella burnetii</em> to doxycycline exposure

Publication date: Available online 5 August 2019Source: Journal of ProteomicsAuthor(s): Fernando Zuñiga-Navarrete, Gabriela Flores-Ramirez, Maksym Danchenko, Oldrich Benada, Anton Skriba, Ludovit SkultetyAbstractAntibiotic resistance is a global threat with a top concern in healthcare. Doxycycline is an antibiotic highly permeable to cell membrane used for treating a broad variety of bacteria, including Coxiella burnetii. This intracellular pathogen is the causative agent of Q fever, a re-emerging...

ScienceDirect Publication: Journal of Proteomics

16h