Antibiotics, Vol. 9, Pages 110: The Use of a Non-Absorbable Membrane as an Occlusive Barrier for Alveolar Ridge Preservation: A One Year Follow-Up Prospective Cohort Study Antibiotics doi: 10.3390/antibiotics9030110 Authors: Papi Di Murro Tromba Passarelli D’Addona Pompa ：The aims of this study were to obtain preliminary data and test the clinical efficacy of a novel nonporous dense-polytetrafluoroethylene (d-PTFE) membrane (permamem®, botiss) in alveolar...
Tue Mar 03, 2020 02:00
Antibiotics, Vol. 9, Pages 109: Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats Antibiotics doi: 10.3390/antibiotics9030109 Authors: Hessel Van der Weide Marian T. Ten Kate Denise M. C. Vermeulen-de Jongh Aart Van der Meijden Rixt A. Wijma Stefan A. Boers Mireille Van Westreenen John P. Hays Wil H. F. Goessens Irma A. J. M. Bakker-Woudenberg Background: Recent scientific reports...
Tue Mar 03, 2020 02:00
Antioxidants, Vol. 9, Pages 209: Assessment of Antioxidants in Selected Plant Rootstocks Antioxidants doi: 10.3390/antiox9030209 Authors: Samuel Magnus Filip Gazdik Naser A. Anjum Eliska Kadlecova Zuzana Lackova Natalia Cernei Martin Brtnicky Jindrich Kynicky Borivoj Klejdus Tomas Necas Ondrej Zitka The service tree (Sorbus domestica) is a wild fruit tree with immense medicinal and industrial value. This study aimed at determining the four major groups of...
Tue Mar 03, 2020 02:00
Antioxidants, Vol. 9, Pages 208: Monoalkylated Epigallocatechin-3-gallate (C18-EGCG) as Novel Lipophilic EGCG Derivative: Characterization and Antioxidant Evaluation Antioxidants doi: 10.3390/antiox9030208 Authors: Cristina Minnelli Roberta Galeazzi Emiliano Laudadio Adolfo Amici Dario Rusciano Tatiana Armeni Mattia Cantarini Pierluigi Stipa Giovanna Mobbili Epigallocatechin-3-gallate (EGCG) has the highest antioxidant activity compared to the others catechins...
Tue Mar 03, 2020 02:00
Antioxidants, Vol. 9, Pages 207: Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment Antioxidants doi: 10.3390/antiox9030207 Authors: Clapper Wang Raninga Di Trapani Tonissen Chronic myeloid leukaemia (CML) is currently treated with inhibitors of the CML specific oncoprotein, bcr-abl. While this strategy is initially successful, drug resistance can become a problem. Therefore, new targets need to be identified...
Tue Mar 03, 2020 02:00
Atmosphere, Vol. 11, Pages 252: Skill Assessment of an Atmosphere–Wave Regional Coupled Model over the East China Sea with a Focus on Typhoons Atmosphere doi: 10.3390/atmos11030252 Authors: Li Staneva Grayek Behrens Feng Yin This study performed several sensitivity experiments to investigate the impact of atmosphere–wave coupling on the simulated wind and waves over the East China Sea (ECS) with a focus on typhoon events. These experiments include stand-alone...
Tue Mar 03, 2020 02:00
Atmosphere, Vol. 11, Pages 254: The Aerosol-Radiation Interaction Effects of Different Particulate Matter Components during Heavy Pollution Periods in China Atmosphere doi: 10.3390/atmos11030254 Authors: Wen Ma Guo Zhao Xu Liu Wu Zhou Zhang : The Beijing-Tianjin-Hebei (BTH) region experienced heavy air pollution in December 2015, which provided a good opportunity to explore the aerosol-radiation interaction (ARI) effects of different particulate matter...
Tue Mar 03, 2020 02:00
Atmosphere, Vol. 11, Pages 253: Characteristics of Air Pollution and Their Relationship with Meteorological Parameters: Northern Versus Southern Cities of China Atmosphere doi: 10.3390/atmos11030253 Authors: Zhou Yu Gu Wu Wang Yue Gao Lei Ge Air pollution shows a generally decreasing trend from the north to the south in China since 2013 (GB3095-2012, the current standard for monitoring). However, an opposite observation was recorded in 2017, especially...
Tue Mar 03, 2020 02:00
Biology, Vol. 9, Pages 46: Effect of Tillage System and Cover Crop on Maize Mycorrhization and Presence of Magnaporthiopsis maydis Biology doi: 10.3390/biology9030046 Authors: Patanita Campos Félix Carvalho Brito The sustainability of agriculture requires the adoption of agricultural soil conservation practices with positive impacts on soil quality, which can promote beneficial soil microbiota like arbuscular mycorrhizal fungi (AMF) and its diversity. This study aims...
Tue Mar 03, 2020 02:00
Biomedicines, Vol. 8, Pages 49: Three-Dimensional Model of Dorsal Root Ganglion Explant as a Method of Studying Neurotrophic Factors in Regenerative Medicine Biomedicines doi: 10.3390/biomedicines8030049 Authors: Klimovich Rubina Sysoeva Semina Neurotrophiс factors play a key role in the development, differentiation, and survival of neurons and nerve regeneration. In the present study, we evaluated the effect of certain neurotrophic factors (NGF, BDNF, and GDNF) on axon...
Tue Mar 03, 2020 02:00
Biomimetics, Vol. 5, Pages 9: The Ground Effect in Anguilliform Swimming Biomimetics doi: 10.3390/biomimetics5010009 Authors: Uchenna E Ogunka Mohsen Daghooghi Amir M Akbarzadeh Iman Borazjani Some anguilliform swimmers such as eels and lampreys swim near the ground, which has been hypothesized to have hydrodynamic benefits. To investigate whether swimming near ground has hydrodynamics benefits, two large-eddy simulations of a self-propelled anguilliform swimmer are carried...
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 392: Interplay between Endoplasmic Reticulum (ER) Stress and Autophagy Induces Mutant p53H273 Degradation Biomolecules doi: 10.3390/biom10030392 Authors: Garufi Federici Gilardini Montani Crispini Cirone D’Orazi The unfolded protein response (UPR) is an adaptive response to intrinsic and external stressors, and it is mainly activated by the accumulation of misfolded proteins at the endoplasmic reticulum (ER) lumen producing ER stress....
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 393: Homocysteine Induces Inflammation in Retina and Brain Biomolecules doi: 10.3390/biom10030393 Authors: Elsherbiny Sharma Kira Alhusban Samra Jadeja Martin Al-Shabrawey Tawfik Homocysteine (Hcy) is an amino acid that requires vitamins B12 and folic acid for its metabolism. Vitamins B12 and folic acid deficiencies lead to hyperhomocysteinemia (HHcy, elevated Hcy), which is linked to the development of diabetic retinopathy...
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 389: Galectin-3 as a Next-Generation Biomarker for Detecting Early Stage of Various Diseases Biomolecules doi: 10.3390/biom10030389 Authors: Hara Niwa Noguchi Kanayama Niwa Matsuo Hatano Tomita Galectin-3 is a β-galactoside-binding lectin which is important in numerous biological activities in various organs, including cell proliferation, apoptotic regulation, inflammation, fibrosis, and host defense. Galectin-3 is predominantly...
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 391: Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts
Biomolecules, Vol. 10, Pages 391: Targeting α-synuclein for PD Therapeutics: A Pursuit on All Fronts Biomolecules doi: 10.3390/biom10030391 Authors: Teil Arotcarena Faggiani Laferriere Bezard Dehay Parkinson’s Disease (PD) is characterized both by the loss of dopaminergic neurons in the substantia nigra and the presence of cytoplasmic inclusions called Lewy Bodies. These Lewy Bodies contain the aggregated α-synuclein (α-syn) protein,...
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 388: TSPAN8 as a Novel Emerging Therapeutic Target in Cancer for Monoclonal Antibody Therapy Biomolecules doi: 10.3390/biom10030388 Authors: Heo Lee Tetraspanin 8 (TSPAN8) is a member of the tetraspanin superfamily that forms TSPAN8-mediated protein complexes by interacting with themselves and other various cellular signaling molecules. These protein complexes help build tetraspanin-enriched microdomains (TEMs) that efficiently mediate intracellular...
Tue Mar 03, 2020 02:00
Biomolecules, Vol. 10, Pages 390: Altered Plasma Acylcarnitines and Amino Acids Profile in Spinocerebellar Ataxia Type 7 Biomolecules doi: 10.3390/biom10030390 Authors: Nambo-Venegas Valdez-Vargas Cisneros Palacios-González Vela-Amieva Ibarra-González Cerecedo-Zapata Martínez-Cruz Cortés Reyes-Grajeda Magaña Spinocerebellar ataxia type 7 (SCA7), a neurodegenerative disease characterized by cerebellar ataxia and retinal degeneration, is caused...
Tue Mar 03, 2020 02:00
Biosensors, Vol. 10, Pages 21: The Growing Interest in Development of Innovative Optical Aptasensors for the Detection of Antimicrobial Residues in Food Products Biosensors doi: 10.3390/bios10030021 Authors: Valérie Gaudin The presence of antimicrobial residues in food-producing animals can lead to harmful effects on the consumer (e.g., allergies, antimicrobial resistance, toxicological effects) and cause issues in food transformation (i.e., cheese, yogurts production). Therefore, to...
Tue Mar 03, 2020 02:00
Biosensors, Vol. 10, Pages 20: Surface Probe Linker with Tandem Anti-Fouling Properties for Application in Biosensor Technology Biosensors doi: 10.3390/bios10030020 Authors: Spagnolo Franier Hianik Thompson This paper describes the anti-fouling capability of the novel monolayer-forming surface linker 3-(3-(trichlorosilylpropyloxy) propanoyl chloride (MEG-Cl). This compound was successfully attached to quartz crystal surfaces which are employed in an electromagnetic piezoelectric...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 585: Expression of Interleukin-6 and the Interleukin-6 Receptor Predicts the Clinical Outcomes of Patients with Soft Tissue Sarcomas Cancers doi: 10.3390/cancers12030585 Authors: Koichi Nakamura Tomoki Nakamura Takahiro Iino Tomohito Hagi Kouji Kita Kunihiro Asanuma Akihiro Sudo Interleukin-6 (IL-6) affects the key parameters of oncogenesis, which increases the cell resistance to apoptosis, the proliferation of cancer cells, angiogenesis, invasion,...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 583: Pan Aurora Kinase Inhibitor: A Promising Targeted-Therapy in Dedifferentiated Liposarcomas With Differential Efficiency Depending on Sarcoma Molecular Profile Cancers doi: 10.3390/cancers12030583 Authors: Mattei Bouvier-Labit Barets Macagno Chocry Chibon Morando Rochwerger Duffaud Olschwang Salas Jiguet-Jiglaire Soft tissue sarcoma (STS) are rare and aggressive tumours. Their classification includes numerous histological...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 581: Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells † Cancers doi: 10.3390/cancers12030581 Authors: Sandforth Ammar Dinges Röcken Arlt Sebens Schäfer Metabolite exchange between stromal and tumor cells or among tumor cells themselves accompanies metabolic reprogramming in cancer including pancreatic adenocarcinoma (PDAC). Some tumor...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 582: Radiosensitization by Hyperthermia: The Effects of Temperature, Sequence, and Time Interval in Cervical Cell Lines Cancers doi: 10.3390/cancers12030582 Authors: Mei ten Cate van Leeuwen Rodermond de Leeuw Dimitrakopoulou Stalpers Crezee Kok Franken Oei Cervical cancers are almost exclusively caused by an infection with the human papillomavirus (HPV). When patients suffering from cervical cancer have contraindications...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 584: Current Role of Total Laryngectomy in the Era of Organ Preservation Cancers doi: 10.3390/cancers12030584 Authors: Bozec Culié Poissonnet Dassonville In this article, we aimed to discuss the role of total laryngectomy (TL) in the management of patients with larynx cancer (LC) in the era of organ preservation. Before the 1990s, TL followed by radiotherapy (RT) was the standard treatment for patients with locally advanced LC. Over the last 30 years,...
Tue Mar 03, 2020 02:00
Cancers, Vol. 12, Pages 580: Serine Biosynthesis Pathway Supports MYC–miR-494–EZH2 Feed-Forward Circuit Necessary to Maintain Metabolic and Epigenetic Reprogramming of Burkitt Lymphoma Cells Cancers doi: 10.3390/cancers12030580 Authors: Białopiotrowicz Noyszewska-Kania Kachamakova-Trojanowska Łoboda Cybulska Grochowska Kopczyński Mikula Prochorec-Sobieszek Firczuk Graczyk-Jarzynka Zagożdżon Ząbek Młynarz Dulak Górniak Szydłowski...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 603: PPE51 Is Involved in the Uptake of Disaccharides by Mycobacterium tuberculosis Cells doi: 10.3390/cells9030603 Authors: Małgorzata Korycka-Machała Jakub Pawełczyk Paulina Borówka Bożena Dziadek Anna Brzostek Malwina Kawka Adrian Bekier Sebastian Rykowski Agnieszka B. Olejniczak Dominik Strapagiel Zbigniew Witczak Jarosław Dziadek We have recently found that selected thio-disaccharides possess bactericidal effects against Mycobacterium...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 606: The Winner Takes It All: Auxin–The Main Player during Plant Embryogenesis Cells doi: 10.3390/cells9030606 Authors: Konrad Winnicki In plants, the first asymmetrical division of a zygote leads to the formation of two cells with different developmental fates. The establishment of various patterns relies on spatial and temporal gene expression, however the precise mechanism responsible for embryonic patterning still needs elucidation. Auxin seems to be the main...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 605: Probing the Environment of Emerin by Enhanced Ascorbate Peroxidase 2 (APEX2)-Mediated Proximity Labeling Cells doi: 10.3390/cells9030605 Authors: Marret Müller Christina James Christof Lenz Henning Urlaub Ralph H. Kehlenbach Emerin is one of the best characterized proteins of the inner nuclear membrane, but can also occur at the level of the endoplasmic reticulum. We now use enhanced ascorbate peroxidase 2 (APEX2) to probe the environment of emerin....
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 604: Propranolol Suppresses the T-Helper Cell Depletion-Related Immune Dysfunction in Cirrhotic Mice Cells doi: 10.3390/cells9030604 Authors: Hung-Cheng Tsai Chien-Fu Hsu Chia-Chang Huang Shiang-Fen Huang Tzu-Hao Li Ying-Ying Yang Ming-Wei Lin Tzung-Yan Lee Chih-Wei Liu Yi-Hsiang Huang Ming-Chih Hou Han-Chieh Lin Bacterial translocation (BT) and splenomegaly contribute to cirrhosis-associated immune dysfunction (CAID) including T...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 607: Fluorinated Galactoses Inhibit Galactose-1-Phosphate Uridyltransferase and Metabolically Induce Galactosemia-like Phenotypes in HEK-293 Cells Cells doi: 10.3390/cells9030607 Authors: Verena Janes Simona Grabany Julien Delbrouck Stephane P. Vincent Johannes Gottschalk Lothar Elling Franz-Georg Hanisch Genetic defects of human galactose-1-phosphate uridyltransferase (hGALT) and the partial loss of enzyme function result in an altered galactose...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 602: Designing Novel Therapies to Mend Broken Hearts: ATF6 and Cardiac Proteostasis Cells doi: 10.3390/cells9030602 Authors: Erik A. Blackwood Alina S. Bilal Winston T. Stauffer Adrian Arrieta Christopher C. Glembotski The heart exhibits incredible plasticity in response to both environmental and genetic alterations that affect workload. Over the course of development, or in response to physiological or pathological stimuli, the heart responds to fluctuations...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 599: Melatonin’s Antineoplastic Potential Against Glioblastoma Cells doi: 10.3390/cells9030599 Authors: Moretti Favero Rodella Rezzani Glioblastoma (GBM) is one of the most intransigent and aggressive brain tumors, and its treatment is extremely challenging and ineffective. To improve patients’ expectancy and quality of life, new therapeutic approaches were investigated. Melatonin is an endogenous indoleamine with an incredible variety of properties....
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 600: Astrocyte and Oligodendrocyte Cross-Talk in the Central Nervous System Cells doi: 10.3390/cells9030600 Authors: Erik Nutma Démi van Gent Sandra Amor Laura A. N. Peferoen Over the last decade knowledge of the role of astrocytes in central nervous system (CNS) neuroinflammatory diseases has changed dramatically. Rather than playing a merely passive role in response to damage it is clear that astrocytes actively maintain CNS homeostasis by influencing...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 597: 3,4-Dihydroxybenzalacetone (DBL) Prevents Aging-Induced Myocardial Changes in Senescence-Accelerated Mouse-Prone 8 (SAMP8) Mice Cells doi: 10.3390/cells9030597 Authors: Giridharan Karupppagounder Arumugam Nakamura Guha Barichello Quevedo Watanabe Konishi Thandavarayan Aging is a predominant risk factor for the development and progression of cardiovascular complications. Physiologically and anatomically, the heart undergoes...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 596: Multifaceted Aspects of Metabolic Plasticity in Human Cholangiocarcinoma: An Overview of Current Perspectives Cells doi: 10.3390/cells9030596 Authors: Pastore Lori Gentilini Taddei Di Maira Campani Recalcati Invernizzi Marra Raggi Cholangiocarcinoma (CCA) is a deadly tumor without an effective therapy. Unique metabolic and bioenergetics features are important hallmarks of tumor cells. Metabolic plasticity allows cancer cells...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 598: Inter-Organelle Membrane Contact Sites and Mitochondrial Quality Control during Aging: A Geroscience View Cells doi: 10.3390/cells9030598 Authors: Picca Calvani Coelho-Junior Landi Bernabei Marzetti Mitochondrial dysfunction and failing mitochondrial quality control (MQC) are major determinants of aging. Far from being standalone organelles, mitochondria are intricately related with cellular other compartments, including lysosomes. The intimate...
Tue Mar 03, 2020 02:00
Cells, Vol. 9, Pages 601: Immunotherapy in Multiple Myeloma Cells doi: 10.3390/cells9030601 Authors: Soekojo Ooi de Mel Chng Multiple myeloma is a complex disease and immune dysfunction has been known to play an important role in the disease pathogenesis, progression, and drug resistance. Recent efforts in drug development have been focused on immunotherapies to modify the MM disease process. Here, we summarize the emerging immunotherapies in the MM treatment landscape.
Tue Mar 03, 2020 02:00
Children, Vol. 7, Pages 17: Using the SITAR Method to Estimate Age at Peak Height Velocity of Children in Rural South Africa: Ellisras Longitudinal Study Children doi: 10.3390/children7030017 Authors: Chris Nembidzane ‘Maseka Lesaoana Kotsedi Daniel Monyeki Alexander Boateng Phuti J. Makgae Various studies have been conducted on children using the Ellisras Longitudinal Study Survey in South Africa, but none of these has addressed growth variations of children in this rural...
Tue Mar 03, 2020 02:00
Diagnostics, Vol. 10, Pages 140: Clinical versus Ultrasound Measurements of Hyomental Distance Ratio for the Prediction of Difficult Airway in Patients with and without Morbid Obesity Diagnostics doi: 10.3390/diagnostics10030140 Authors: Petrișor Trancă Szabo Simon Prie Bodolea Purpose: To describe the correlation between clinically measured hyomental distance ratio (HMDRclin) and the ultrasound measurement (HMDRecho) in patients with and without morbid obesity and...
Tue Mar 03, 2020 02:00
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