Botulinum toxin in the management of temporomandibular disorders: a systematic review

Botulinum toxin in the management of temporomandibular disorders: a systematic review: The aim of this review was to critically investigate and assess the evidence relating to the use and efficacy of botulinum toxin (BTX) in the management of temporomandibular joint disorders (TMD) and masticatory myofascial pain. A comprehensive search was conducted of PubMed, Scopus, Embase, and Cochrane CENTRAL, to find relevant studies from the last 30 years up to the end of July 2018. Seven were identified. Three showed a significant reduction in pain between the BTX and placebo groups and one showed a clinical, but not a significant, difference. (Source: The British Journal of Oral and Maxillofacial Surgery)