Abstract Objectives Podcasts are audio recordings distributed via the Internet. We review the availability of podcasts on the topic of radiology. Methods A search for podcasts relating to radiology was performed using search engines and free public websites that either hosted or distributed podcasts. Only English language podcast series were...
Abstract Objectives This study aimed to investigate the application of shear wave elastography (SWE) in the early damage detection through assessing the endometrial elasticity after artificial abortion. Methods A total of nulliparous women (20–30 years) who received ultrasonography in our hospital were recruited between January 2017 and December...
Abstract Background Ninety years after the Dutch theoretical physicist H.A. Lorentz died, detailed investigation of his scientific heritage yielded the set of nine original prints of radiographs that W.C. Roentgen made during his experiments and had sent him, among half a dozen other scientists, on January 1st, 1896. Main text Through communications...
Abstract The aim of the study is to perform an analysis of the results that have been compiled in the nine years that the examination has existed.
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Summary Introduction Durvalumab has been shown to confer a survival benefit after definitive chemoradiotherapy in the patients with locally advanced non-small cell lung cancer, but no studies have attempted to identify risk factors for pneumonitis after durvalumab therapy. The purpose of this study was to investigate associations between clinical and radiation dose-volume factors, and the severity of pneumonitis. Methods We retrospectively assessed the cases of 30 patients who...
Summary This phase 1 study sought to characterize the safety, tolerability, and pharmacokinetic behavior of VLX1570, a small molecule inhibitor of the deubiquitinases (DUBs) that remove sterically bulky ubiquitin chains from proteins during processing in the19S regulatory subunit of the proteasome, in patients with relapsed and refractory multiple myeloma (MM). Fourteen patients were treated with escalating doses of VLX1570 ranging from 0.05 to 1.2 mg/kg as a brief intravenous...
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Abstract The potential of indigenously isolated bacteria from the Estância Velha stream to reduce Cr(VI) was evaluated and also the chromium contamination over the past ten years was verified in one of the most important industrial centers of Brazil, the “Brazilian Capital of Tanneries,” Estância Velha municipality in the Rio Grande do Sul State, South Brazil. Samples were collected from the Estância Velha stream at the source (P1), as well as at upstream (P2) and downstream (P3)...
Abstract In the current study, an extracellular cellulase belonging to symbiotic Bacillus subtilis Bc1 of the leopard moth is purified and characterized. The molecular mass of enzyme was 47.8 kDa using SDS-PAGE. The purified enzyme had optimum activity in temperature and pH around 60 °C and 8, respectively. The purified cellulase was introduced as a stable enzyme in a wide variety of temperature (20–80 °C) and pH (4–10) and remained active to more than 74% at 80 °C for 1 h. Moreover,...
Abstract A radio-resistant bacterium labeled as strain TMC-6 was isolated from Thal desert, Pakistan and identified through 16S rRNA gene sequencing as Bacillus indicus strain TMC-6 (MN721293). The isolate was found to be resistant to UV radiation dose of 6.780 × 103 J/m2 and showed 50% survivability to mitomycin C (6 μg/ml) and H2O2 (30 mM). The bacterium showed yellowish orange coloration when grown on tryptone yeast glucose (TGY) medium. The cellular metabolite was extracted...
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Abstract The anterior abdominal wall, which is composed of three layers (skin and adipose tissues; the myofascial layer; and the deep layer, consisting of the transversalis fascia, preperitoneal fat, and the parietal peritoneum), has many functions: containment, support and protection for the intraperitoneal contents, and involvement in movement and breathing. While hernias are often encountered and well reviewed in the literature, the other abdominal wall pathologies are less...
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Abstract Multiple myeloma (MM) almost invariably progresses through novel therapies. Patients with quad-refractory MM (refractory to bortezomib, carfilzomib, lenalidomide, and pomalidomide) and penta-refractory MM (additional refractoriness to daratumumab) have few treatment options. Two chemotherapy regimens, bendamustine/prednisone (BP) and dexamethasone, cyclophosphamide, etoposide, and cisplatin (DCEP), are often used in quad- and penta-refractory MM, but there are limited...
Abstract Aim: To measure histological villous atrophy and to clarify the diagnostic accuracy of endoscopic villous atrophy in gastrointestinal graft-versus-host disease. Methods: Data for patients who underwent upper and/or lower endoscopic examinations after hematopoietic stem cell transplantation were retrospectively collected. In study 1, group A included 56 patients in whom GI-GVHD was histologically confirmed and group B included 60 patients in whom GI-GVHD was not histologically...
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Abstract Purpose IHC, FISH, and NGS are common methods of ALK evaluation in NSCLC. The purpose of this study was to investigate whether ALK false positives or false negatives occurred more often in daily routines. An approach to identify ALK fusion was then proposed. Materials and methods We analyzed 1815 cases of NSCLC, including 83 (4.6%) ALK IHC positives....
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Abstract Counterpart cooperation is a major innovative measure in China’s strategy for revitalizing north-eastern China. While promoting economic progress, regional counterpart cooperation should also focus on low-carbon economy and sustainable development. Under the background of China’s proposed innovative cooperation strategy, using a multi-regional input-output (MRIO) model and structural decomposition analysis (SDA), this study takes Jilin province and its counterpart Zhejiang...
Abstract Leakage of CO2 from the geological storage is a serious issue for the sustainability of the receiving fresh soil–water systems. Subsurface water quality issues are no longer related to one type of pollution in many regions around the globe. Thus, an effort has been made to review studies performed to investigate supercritical CO2 (scCO2) and CO2 enrich brine migration and it's leakage from geological storage formations. Further, the study also reviewed it's impacts on...
Abstract Phosphorus removal from wastewater has become urgent because of eutrophication control. Phosphate concentration in control for phosphate removal and recovery by Mg–Fe oxide has been investigated. The results show that the adsorption capacity of phosphate by Mg–Fe oxide calcined at 450 °C was 28.3 mg/g, and it was kept at wide optimal adsorption pH ranges (4–10). The coexisting ions had influenced phosphate adsorption process and the order is CO32− > SO42− > NO3− > Cl−,...
Abstract 17α-ethinylestradiol (EE2), the female contraceptive pill, has been detected in mediterranean coasts where seahorse populations, Hippocampus guttulatus, live. Low environmental concentrations have the potential to disrupt growth but also endocrine metabolism, and this imbalance is all the more critical in early life stage. To investigate the impact of EE2 in reared seahorses, we exposed aged 2 months and sexually undifferentiated seahorses to an environmental concentration...
Abstract Propranolol hydrochloride is a popular anti-hypertensive and pollutant of emerging concern because of potential ecological risks to aquatic environment. In this study, biosorption is presented as an advanced approach for propranolol uptake from aqueous media. The remaining biomass of alginate extraction from brown seaweed (RSF) was tested as biosorbent owing to its key binding sites, namely carboxyl and hydroxyl functional groups. The high 93% removal efficiency achieved...
Abstract Sub-type source profiles for atmospheric fine particle (PM2.5) were still scare in China, which limited the accurate source identification of it. Fugitive dust (including road dust, soil dust, resuspended dust, and construction dust, etc.) was one type of the most important contributors to PM2.5 and its associated toxic metals held potential threaten to human health. The chemical compositions, sources, and health risks of sub-type fugitive dust deserved an investigation...
Abstract We have studied the black carbon (BC) mass concentrations, contributions from Fossil Fuels (FF), and Biomass burning (BB) to total BC mass concentrations using a 7-wavelength Aethalometer (Model, AE-31; Make, Magee Scientific, USA) at a rural continental location in the northeastern India. We have taken the continuous measurements of BC from January 2011 to December 2017 (excluding the year 2016 due to nonavailability of data). The annual mean BC concentration at 880 nm...
Microporous intermittent aeration vertical flow constructed wetlands for eutrophic water improvement
Abstract To enhance eutrophic water improvement effect, three parallel lab-scale oxidation pond-vertical subsurface flow constructed wetland-stable pond combined systems with different microporous intermittent aeration positions were constructed. The purification effect of each system was determined, and the contribution rate of each part of the system was also calculated. The characters of bacterial community under different aeration positions were also analyzed. Microporous intermittent...
Abstract In order to realize the effective measurement of environmental pollution loss (EPL) caused by waste gas emits from energy consumption in industrial parks, it is built a shadow price model of waste gas emits in this study on the basis of literature review and status analysis. The measurement model is applied to Nanjing MV Industrial Park by using relevant statistical data. It is found that the total environmental pollution loss of waste gas emits from energy consumption...
Abstract This study used a formaldehyde detector tube with a gas-piston hand pump to assess ceiling levels of student breathing zone and gross laboratory environment across the 2018 academic year. The room dimension was 28.6 × 55.48 × 5.5 m. It contained 90 cadavers, each placed on a hinged cover table. We measured before and during nine body region dissections. There was a significant difference (p < 0.01) between student exposure and laboratory environment levels. The highest...
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Zusammenfassung Hintergrund Das Analkarzinom ist in 70–90 % der Fälle mit einer Infektion durch Hochrisikostämme des humanen Papillomavirus (HPV) assoziiert. In den letzten Jahrzehnten wurde ein Anstieg der Inzidenz beobachtet. Die definitive Radiochemotherapie (RCT) mit 5‑Fluorouracil und Mitomycin C stellt die Standardbehandlung für lokalisierte Erkrankungen dar. Allerdings sprechen etwa 30 % der Patienten mit lokal fortgeschrittenen...
Zusammenfassung Das proximale, zervikal lokalisierte Ösophaguskarzinom stellt innerhalb der Plattenepithelkarzinome der Speiseröhre eine relativ seltene Untergruppe mit besonders schlechter Prognose dar. Es erfolgte die Auswertung der entsprechenden Literatur. Eine operative Versorgung erfordert regelhaft eine Mitentfernung von Larynx und Hypopharynx und kommt bei hohen perioperativen Komplikationsraten und schlechter resultierender Lebensqualität nur in Ausnahmefällen zum Einsatz....
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Abstract Background 18F-2-fluoro-2-deoxyglucose (FDG) positron emission tomography (PET) plays an important role in the diagnosis, evaluation and treatment of childhood epilepsy. The selection of appropriate acquisition and reconstruction parameters, however, can be challenging with the introduction of advanced hardware and software functionalities. Objective ...
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Funktionelle Ergebnisse nach Rekonstruktion des weichen Gaumens bei Patienten mit Oropharynxkarzinom
Zusammenfassung Hintergrund Die operative Therapie von Karzinomen des Oropharynx mir Beteiligung des weichen Gaumens kann Einschränkungen in Bezug auf die Schluck‑, Stimm- und Sprechkompetenz hervorrufen. Die Rekonstruktion der resezierten Strukturen kann dazu beitragen, die Funktionalität posttherapeutisch wiederherzustellen. Ziel der Arbeit Ziel der durchgeführten...
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Abstract Budesonide is a glucocorticoid for the treatment of ulcerative colitis (UC). The current study aims to develop a thermosensitive in situ and adhesive gel for rectal delivery of budesonide. HPMC K4M was selected as the adhesive agent based on the adhesive force and the effect on gel performance. The formulation of gel was optimized by using the central composite design-response surface methodology (CCD-RSM); a mathematical model was successfully developed to predict...
Abstract Oseltamivir is a neuraminidase inhibitor widely used to treat and prevent influenza A and B infections, although its safety and pharmacokinetics have not been evaluated in patients with severe hepatic impairment. A physiologically based pharmacokinetic (PBPK) model of the prodrug oseltamivir and its active metabolite, oseltamivir carboxylate (OC), was established and validated to simulate their disposition in adults and predict the exposure in patients with Child-Pugh...
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