Journal of Neurotrauma, Ahead of Print.
Journal of Neurotrauma, Ahead of Print.
Abstract Purpose The pathophysiologic mechanisms of contrast enhancement (CE) of middle cerebral artery (MCA) plaque remain unclear since histologic and imaging findings have never been compared. The purpose of this study was to assess the pattern of CE between patients with MCA stenosis or occlusion and in an MCA stenotic silicone model. Methods We retrospectively...
Abstract Previous reports have identified a small, benign, high-signal lesion (HSL) posterior to the intracranial vertebral artery and associated with the ipsilateral spinal accessory nerve (SAN) using 3D fluid-attenuated inversion recovery (3D FLAIR) imaging as an emerging new entity. To elucidate the relationship between HSLs and SAN, 76 patients with 86 HSLs were evaluated using 3D FLAIR and 3D balanced fast-field echo (3D bFFE imaging). All HSLs showed contact with ipsilateral...
Publication date: Available online 5 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): M. Mansour, M. Ben Mahmoud, A.kacem, J. Zaouali, R. MrissaAbstractMelkersson-Rosenthal (MRS) syndrome is a rare disorder defined as a triad of recurrent peripheral facial palsy, orofacial edema, and fissured tongue. The etiology of this disease is still unclear. Genetic origin has been postulated. Several theories have been advanced to provide further evidence for a hereditary basis of MRS. We describe...
Publication date: October 2019Source: World Neurosurgery, Volume 130Author(s): Min Gyu Kang, Kyung Hyun Kim, Jeong Yoon Park, Seong Wook Koo, Dong Kyu Chin, Keun Su Kim, Yong Eun ChoBackgroundA 61-year-old man was admitted complaining of myelopathy and back pain for 3 months.Case DescriptionA 15-mm hemangioma with calcification was noted on magnetic resonance imaging and computed tomography. Intraoperatively, the mass was hard with ill-defined demarcation. The cranial portion of the mass was brown...
Publication date: Available online 5 August 2019Source: NeuroImageAuthor(s): Conrad W. Merkle, Jun Zhu, Marcel T. Bernucci, Vivek J. SrinivasanAbstractStudies of flow-metabolism coupling often presume that microvessel architecture is a surrogate for blood flow. To test this assumption, we introduce an in vivo Dynamic Contrast Optical Coherence Tomography (DyC-OCT) method to quantify layer-resolved microvascular blood flow and volume across the full depth of the mouse neocortex, where the angioarchitecture...
Publication date: Available online 5 August 2019Source: Journal of Neuroscience MethodsAuthor(s): Kleber Neves, Daniel Menezes Guimarães, Danielle Rayêe, Bruna Valério-Gomes, Pamela Meneses Iack, Roberto Lent, Bruno MotaAbstractBackgroundThe Isotropic Fractionator (IF) is a method to determine the cellular composition of nervous tissue. It has been mostly applied to assess variation across species, where differences are expected to be large enough not to be masked by methodological error. However,...
Longitudinal spinal cord atrophy in multiple sclerosis using the generalised boundary shift integral
ABSTRACT Objectives Spinal cord atrophy is a clinically relevant feature of multiple sclerosis (MS), but longitudinal assessments on MRI using segmentation‐based methods suffer from measurement variability, especially in multicentre studies. We compared the generalised boundary shift integral (GBSI), a registration‐based method, with standard segmentation‐based method. Methods Baseline and 1‐year spinal cord 3DT1‐weighted images (1mm isotropic) were obtained from 282 patients (52 clinically...
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