- [ASAP] Nonstationary Two-Dimensional Nuclear Magnetic Resonance: A Method for Studying Reaction Mechanisms in SituAnalytical ChemistryDOI: 10.1021/acs.analchem.9b02414
- Άνοια: Ο παράγοντας που αυξάνει τον κίνδυνο κατά 49%Ερευνητές του Πανεπιστημίου Johns Hopkins μελέτησαν για πάνω από δύο δεκαετίες περισσότερα από 4,700 άτομα και κατέληξαν στο συμπέρασμα ότι ένας παράγοντας κατά τη μέση ηλικία μπορεί να αυξήσει τις πιθανότητες εκδήλωσης άνοιας κατά την Τρίτη Ηλικία. Σύμφωνα με σχετικό άρθρο που δημοσιεύουν στο JAMA, η μη φυσιολογική αρτηριακή πίεση κατά την μέση ηλικία που συνεχίζει να υφίσταται και κατά την Τρίτη Ηλικία αποτελεί παράγοντα κινδύνου για την εκδήλ
- <i>Amycolatopsis alkalitolerans</i> sp. nov., isolated from <i>Gastrodia elata</i> BlumeThe Journal of Antibiotics, Published online: 21 August 2019; doi:10.1038/s41429-019-0222-8Amycolatopsis alkalitolerans sp. nov., isolated from Gastrodia elata Blume
- Occipital and Cerebellar Theta Burst Stimulation for Mal De Debarquement SyndromeBackground: Individuals with Mal de Debarquement syndrome (MdDS) experience persistent oscillating vertigo lasting for months or years. Transcranial magnetic stimulation (TMS) can modulate the motion perception of MdDS. Materials and Methods: Twenty-six TMS naive individuals received single administrations of continuous theta burst stimulation (cTBS) over the occipital cortex, cerebellar vermis, and lateral cerebellar hemisphere, in rando
- Lessons From an Analysis of Newborn Hearing Screening Data for Children With Cochlear ImplantsObjectives: The aims of the study are to identify the limitations of the current newborn hearing screening (NHS) programs and provide recommendations for better protocols. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: The study participants were 185 children who received cochlear implants (CIs) at ≤5 years of age. Interventions: Therapeutic and rehabilitative. Main Outcome Measures:
- Factors Influencing Pediatric Cochlear Implant Outcomes: Carolina Sibling StudyObjective: To determine the correlation between speech perception performance between pediatric sibling pairs with severe to profound sensory hearing loss receiving cochlear implants, and in cases of discordance in performance, determine which variables negatively impacted performance. Study Design: Retrospective chart review. Setting: Tertiary academic referral center. Subjects: Eighty-nine pediatric subjects, 43 sibling groups
- The Antrum–Malleus–Tegmen Score: A Pilot Study Assessing Preoperative Radiographic Predictors for Transcanal Endoscopic Cholesteatoma DissectionObjective: Identify features on computed tomography (CT) that predict mastoidectomy conversion (MC) during transcanal endoscopic ear surgery (TEES). Study Design: Retrospective case-control. Setting: University otology practice. Patients: Consecutive patients with cholesteatoma. Intervention: TEES cholesteatoma dissection versus those requiring MC. Main Outcome Measures: Antrum opacification, depth of scutum involvemen
- The Feasibility to Isolate and Expand Tympanic Membrane Squamous Epithelium Stem Cells From Scarred Perforation MarginsHypothesis: The scarred rim of chronic tympanic membrane (TM) perforation contains keratinocytes with potential for regeneration while maintaining their morphological and genetic characteristics. Background: The squamous epithelium of the TM has a good regeneration capacity. Successful isolation and expansion of human TM keratinocytes (hTMKR) was reported from a full, en-bloc, healthy TM. Methods: Trimmed margins of the TM perforatio
- The Septo-Capsulopalpebral fascial Recession Flap technique in Lower Blepharoplasty; An experience of 453 consecutive cases and a review of the literaturePublication date: Available online 21 August 2019Source: Journal of Plastic, Reconstructive & Aesthetic SurgeryAuthor(s): Bok Ki Jung, Young Seok Kim, Woong Ki Jung, Ji Myung Kim, Yeon Ho Jung, Tai Suk RohSummaryBackgroundLower blepharoplasty is one of the most common cosmetic rejuvenation procedures. Occasionally, adverse effects of the operation, ranging from operated and somewhat flattened unnatural look of the lower eyelid region to more
- Influence of Voice Focus Adjustments on Oral-Nasal Balance in Speech and SongObjectives: This study investigated the effect of training backward and forward voice focus adjustments on oral-nasal balance in speech and singing in typical speakers. Methods: Twenty participants (10M/10F) aged 24.25 (SD 3.73) years read phonetically balanced, nasal and oral speech stimuli, and sang a song in both forward and backward voice focus conditions. A Nasometer 6450 was used to obtain nasalance scores in the different conditions. Resul
- An Exploration of the Rapid Automatic Naming Test as Administered to Brazilian ChildrenObjective: The purpose of this research was to conduct an exploratory study of the performance of Brazilian children on the Rapid Automatic Naming (RAN) test, examining schooling effects of schooling and associations with reading speed, comprehension, and reading level for each of the RAN subtests of colour, numbers, letters, and objects. Methods: Participants were 97 children, aged 7–11 years, enrolled in the first to fifth grade of elementary p
- Occipital and Cerebellar Theta Burst Stimulation for Mal De Debarquement SyndromeBackground: Individuals with Mal de Debarquement syndrome (MdDS) experience persistent oscillating vertigo lasting for months or years. Transcranial magnetic stimulation (TMS) can modulate the motion perception of MdDS. Materials and Methods: Twenty-six TMS naive individuals received single administrations of continuous theta burst stimulation (cTBS) over the occipital cortex, cerebellar vermis, and lateral cerebellar hemisphere, in rando
- Lessons From an Analysis of Newborn Hearing Screening Data for Children With Cochlear ImplantsObjectives: The aims of the study are to identify the limitations of the current newborn hearing screening (NHS) programs and provide recommendations for better protocols. Study Design: Retrospective analysis. Setting: Tertiary referral center. Patients: The study participants were 185 children who received cochlear implants (CIs) at ≤5 years of age. Interventions: Therapeutic and rehabilitative. Main Outcome Measures:
- Factors Influencing Pediatric Cochlear Implant Outcomes: Carolina Sibling StudyObjective: To determine the correlation between speech perception performance between pediatric sibling pairs with severe to profound sensory hearing loss receiving cochlear implants, and in cases of discordance in performance, determine which variables negatively impacted performance. Study Design: Retrospective chart review. Setting: Tertiary academic referral center. Subjects: Eighty-nine pediatric subjects, 43 sibling groups
- The Antrum–Malleus–Tegmen Score: A Pilot Study Assessing Preoperative Radiographic Predictors for Transcanal Endoscopic Cholesteatoma DissectionObjective: Identify features on computed tomography (CT) that predict mastoidectomy conversion (MC) during transcanal endoscopic ear surgery (TEES). Study Design: Retrospective case-control. Setting: University otology practice. Patients: Consecutive patients with cholesteatoma. Intervention: TEES cholesteatoma dissection versus those requiring MC. Main Outcome Measures: Antrum opacification, depth of scutum involvemen
- The Feasibility to Isolate and Expand Tympanic Membrane Squamous Epithelium Stem Cells From Scarred Perforation MarginsHypothesis: The scarred rim of chronic tympanic membrane (TM) perforation contains keratinocytes with potential for regeneration while maintaining their morphological and genetic characteristics. Background: The squamous epithelium of the TM has a good regeneration capacity. Successful isolation and expansion of human TM keratinocytes (hTMKR) was reported from a full, en-bloc, healthy TM. Methods: Trimmed margins of the TM perforatio
- Mechanisms Associated with the Adverse Vascular Consequences of Rapid Posthypothermic Rewarming and Their Therapeutic Modulation in RatsTherapeutic Hypothermia and Temperature Management, Ahead of Print.
- Cortical Oscillations and Connectivity During Postoperative RecoveryBackground: The objective of this study was to test whether postoperative electroencephalographic (EEG) biomarkers, parietal alpha power and frontal-parietal connectivity, were associated with measures of clinical recovery in adult surgical patients. Methods: This is a secondary analysis of a prospective cohort study that analyzed intraoperative connectivity patterns in adult surgical patients (N=53). Wireless, whole-scalp EEG data were c
- Huge US government study to offer genetic counsellingNature, Published online: 21 August 2019; doi:10.1038/d41586-019-02509-4A firm hired by the National Institutes of Health will work with participants in a research programme that plans to sequence one million genomes.
- Three tales the river toldNature, Published online: 21 August 2019; doi:10.1038/d41586-019-02478-8A glimpse of the past.
- How to spot a hardy opportunistic infectionNature, Published online: 21 August 2019; doi:10.1038/d41586-019-02487-7Gut-dwelling bacteria produce molecules that could reveal who is prone to a life-threatening consequence of antibiotic treatment.
- Black-hole meal, banana-killer and hottest July everNature, Published online: 21 August 2019; doi:10.1038/d41586-019-02471-1The week in science: 16–22 August 2019.
- Editorial BoardPublication date: October 2019Source: Medical Hypotheses, Volume 131Author(s):
- Cytosolic non-vesicular dopamine accumulation as the predominant mechanism for developing non-DOPA responsive parkinsonism in late-stage Huntington diseasePublication date: Available online 21 August 2019Source: Medical HypothesesAuthor(s): Rafael Vincent M. ManaloAbstractDisturbances in motor movement can have similar clinical presentations, albeit having different pathways and temporal onset. Hypokinetic movements present with rigidity, resting tremors, postural instability and bradykinesia, as seen in parkinsonism, while hyperkinetic movements typically present with chorea, ballismus, tic, athet
- Inhibition of neuronal ferroptosis in the acute phase of intracerebral hemorrhage shows long-term cerebroprotective effectsPublication date: Available online 20 August 2019Source: Brain Research BulletinAuthor(s): Bin Chen, Zhenghong Chen, Mingjian Liu, Xiaorong Gao, Yijun Cheng, Yongxu Wei, Zhebao Wu, Derong Cui, Hanbing ShangAbstractIntracerebral hemorrhage (ICH) is a devastating subtype of stroke because it has few viable therapeutic options to intervene against primary or second brain injury. Recently, evidence has suggested that ferroptosis, a nonapoptotic form
- The Tübingen Palatal Plate Approach to Robin sequence: Summary of Current EvidencePublication date: Available online 20 August 2019Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Christian F. Poets, Bernd Koos, Siegmar Reinert, Cornelia WiechersSummaryVarious treatments, many of them considerably invasive, are currently applied to infants with Robin sequence (RS) and accompanying upper airway obstruction (UAO). We present a narrative review of our data on the Tübingen palatal plate (TPP), which show the following: a)
- Addressing the threat from within: Investigation of respiratory symptoms in a health care worker with untreated latent tuberculosis infectionPublication date: Available online 20 August 2019Source: American Journal of Infection ControlAuthor(s): Anita R. Modi, Cyndee C. Miranda, Gary W. Procop, Charles B. Foster, Susan Harrington, David Evans, Lucileia Teixeira Johnson, Steven M. GordonTuberculosis (TB) in the health care worker demands orchestrated efforts from health care institutions to promptly identify cases and address community risk. We describe a pediatric intensive care unit
- Efficacy of a novel ultraviolet light-emitting diode device for decontamination of shared pens in a health care settingPublication date: Available online 20 August 2019Source: American Journal of Infection ControlAuthor(s): Erica Emig, Heba Alhmidi, Yilen K. Ng-Wong, Thriveen S.C. Mana, Jennifer L. Cadnum, Curtis J. DonskeyShared pens and styluses are a potential source for transmission of health care–associated pathogens and respiratory viruses in health care facilities. A novel ultraviolet light-emitting diode device was effective in reducing bacteria and virus
- A scoping review to assess the impact of public education campaigns to affect behavior change pertaining to antimicrobial resistancePublication date: Available online 20 August 2019Source: American Journal of Infection ControlAuthor(s): Hayley Fletcher-Miles, John Gammon, Sharon Williams, Julian HuntBackgroundYears of global antibiotic misuse has led to the progression of antimicrobial resistance (AMR), posing a direct threat to public health. To impact AMR and maintain antimicrobial viability, educational interventions toward fostering positive AMR behavior change have been
- Prevention of the transmission of Babesia rossi by Haemaphysalis elliptica in dogs treated with Nexgard®Authors: Frederic Beugnet, Wilfried Lebon and Christa de Vos.<br />Parasite Vol. 26 , page 49<br /> Keywords: Afoxolaner ; NexGard ; Dog ; Haemaphysalis elliptica ; Babesia rossi ; Prevention.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/tIKNJjQBb3Y" height="1" width="1" alt=""/>
- A new genus and species of pinworm (Nematoda, Oxyuridae) from the gray mouse opossum, Tlacuatzin canescensAuthors: F. Agustín Jiménez, Juan Manuel Caspeta-Mandujano and Sergio Albino-Miranda.<br />Parasite Vol. 26 , page 50<br /> Keywords: Tlacuatzoxyuris simpsoni ; Tlacuatzin canescens ; Great American Biotic Interchange ; Endemism ; Oxyuridae ; Scientific collections.<img src="http://feeds.feedburner.com/~r/edp_parasite/~4/-5kzaMJq04E" height="1" width="1" alt=""/>
- Implant-supported 2-unit cantilevers compared with single crowns on adjacent implants: A comparative retrospective case seriesPublication date: Available online 20 August 2019Source: The Journal of Prosthetic DentistryAuthor(s): Andrea Roccuzzo, Simon Storgård Jensen, Nils Worsaae, Klaus GotfredsenAbstractStatement of problemThe replacement of 2 adjacent missing teeth remains a clinical challenge. Among the different treatment options, the use of a single implant to support a 2-unit cantilever fixed dental prosthesis (FDP) has been proposed in situations of limited mesi
- Ισραηλινοί «θεραπεύουν» το μετατραυματικό στρες με το ναρκωτικό MDMAΟ Ναχούμ Πέιτσνικ, θύμα βιασμών, ζούσε επί 20 χρόνια μια κόλαση, αντιμέτωπος με συμπτώματα μετατραυματικού στρες και αδυνατούσε να βρει γαλήνη στη ζωή του μέχρι τη στιγμή που δοκίμασε μια θεραπεία που βασίστηκε στο ναρκωτικό MDMA, γνωστό και ως έκσταση. Ο ίδιος πήρε μέρος στη δεύτερη φάση μιας σειράς τριών κλινικών δοκιμών, που ξεκίνησαν το 2014 και διεξήχθησαν από την καναδική οργάνωση Multidisciplinary Association for Psychedelic Studies (MAPS
- Αυτά τα φάρμακα παίρνουν λιγότερο συχνά οι γυναίκεςΟι γυναίκες έχουν λιγότερες πιθανότητες να λάβουν θεραπεία με στατίνες για τη μείωση της χοληστερόλης ή εξίσου ισχυρή δοσολογία με τους άνδρες όταν τελικά λαμβάνουν αγωγή, υποστηρίζει μια νέα μελέτη. Οι ερευνητές που έκαναν τη σχετική δημοσίευση στο Circulation: Cardiovascular Quality and Outcomes διερεύνησαν πιθανές αιτίες αυτής της διαφοράς, εξετάζοντας δεδομένα 5.693 ατόμων που είχαν επιλεγεί για θεραπεία με στατίνες, με βάση τις κατευθυντήρι
- Ο παράγοντας που κάνει πιο συχνή κατάθλιψη, διπολική διαταραχή και σχιζοφρένειαΜια νέα μελέτη που έγινε από ειδικούς του Πανεπιστημίου του Σικάγο αναδεικνύει τον ισχυρό συσχετισμό μεταξύ της έκθεσης στην ατμοσφαιρική ρύπανση και την αύξηση της συχνότητας των νευροψυχιατρικών διαταραχών. Όπως αναφέρεται σε σχετικό άρθρο του PLoS Biology, οι ερευνητές μελέτησαν στοιχεία από τις ΗΠΑ και τη Δανία και διαπίστωσαν ότι η κακή ποιότητα του αέρα σχετίζεται με τα αυξημένα ποσοστά διπολικής διαταραχής και μείζονος κατάθλιψης στις δύο
- Educational Opportunities for Down-Staging Breast Cancer in Low-Income Countries: an Example from TanzaniaAbstract While more than 90% of breast cancer patients in western countries survive for at least 5 years, the survival rate in Tanzania is less than 45% because of late stage at presentation. The aim of this study was to identify patient and health system factors related to early or late stages of a breast cancer diagnosis. The study was conducted at the Ocean Road Cancer Institute (ORCI) in Dar es Salaam, Tanzania, and include
- Molekulare Biologie, Diagnostik und Therapie von MeningeomenZusammenfassung Meningeome stellen die häufigsten primären intrakraniellen Tumoren dar. Während ca. 80 % der Meningeome einen benignen Verlauf aufweisen, sind etwa 20 % der Tumoren durch aggressives lokales Wachstum, erhöhte Rezidivneigung und einen insgesamt schlechten klinischen Verlauf gekennzeichnet. In den vergangenen 5 Jahren sind zahlreiche neue Erkenntnisse zur Molekularpathologie der Meningeome gewonnen worden, die neb
- A new lineage of segmented RNA viruses infecting animals [NEW RESULTS]Metagenomic sequencing has revolutionised our knowledge of virus diversity, with new virus sequences being reported at a higher rate than ever before. However, virus discovery from metagenomic sequencing usually depends on detectable homology: without a sufficiently close relative, so-called 'dark' virus sequences remain unrecognisable. An alternative approach is to use virus-identification methods that do not depend on detecting homology, such a
- Vitamin D Receptor Gene Polymorphisms and Autoimmune Thyroiditis: Are They Associated with Disease Occurrence and Its Features?Purpose. Vitamin D, besides its role in calcium-phosphorus metabolism, turned out to play a significant immunomodulating function. Until now four single nucleotide polymorphisms of vitamin D receptor gene (VDR), rs2228570 (FokI), rs1544410 (BsmI), rs7975232 (ApaI), and rs731236 (TaqI), have been studied in autoimmune thyroid disorders, with conflicting results. Another functional polymorphism of the VDR gene, rs11568820 (Cdx2), has been shown to
- Identifying Protein Complexes from Dynamic Temporal Interval Protein-Protein Interaction NetworksIdentification of protein complex is very important for revealing the underlying mechanism of biological processes. Many computational methods have been developed to identify protein complexes from static protein-protein interaction (PPI) networks. Recently, researchers are considering the dynamics of protein-protein interactions. Dynamic PPI networks are closer to reality in the cell system. It is expected that more protein complexes can be accu
- <em>Helicobacter pylori</em> is associated with poor prognosis of laryngeal precancerous lesionPublication date: Available online 21 August 2019Source: Auris Nasus LarynxAuthor(s): Min Chen, Yi Fang, Lei Cheng, Haitao WuAbstractObjectivesPrevious evidence suggested Helicobacter pylori (H. pylori) promoted tumorigenesis by inducing inflammation in gastric premalignant disease. Whether this organism affected the development of head and neck precancerous lesion remains unknown. We performed this study to assess the prognostic impact of H. pyl
- Morphological development of the human cochlear nucleusPublication date: Available online 20 August 2019Source: Hearing ResearchAuthor(s): Tara Sankar Roy, Shubhi Saini, Charanjeet Kaur, Indra Pal, Punit Kumar, Tony George Jacob, Alok Thakar, Kallol Kumar RoyAbstractMorphological studies in developing brain determine critical periods of proliferation, neurogenesis, gliogenesis, and apoptosis. During these periods both intrinsic and extrinsic pathological factors can hamper development. These time poi
- Clinical efficacy of a simplified approach to managing chronic temporomandibular disorders: evidence from a 1-year case seriesPublication date: September 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 3Author(s): Ajith D. Polonowita, W. Murray Thomson, Dennis N. ThorburnObjectiveChronic temporomandibular disorder (cTMD) produces orofacial pain and limited jaw function and impacts on quality of life. A clinical case series of patients referred to a hospital specialist service is described here.Study DesignIn a 1-year consecu
- Information for ReadersPublication date: September 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 3Author(s):
- Society PagePublication date: September 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 3Author(s):
- Editorial BoardPublication date: September 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 3Author(s):
- Table of ContentsPublication date: September 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 128, Issue 3Author(s):
- Viral mumps: Increasing occurrences in the vaccinated populationPublication date: Available online 27 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Roger K. Lau, Michael D. TurnerBefore the introduction of the vaccine, mumps was the most common salivary gland disease and was one of the most common infectious diseases in children globally. Following the introduction of the mumps vaccine in 1967, the disease was almost nonexistent in the United States and was only fou
- The diagnostic role of ultrasonography, computed tomography, magnetic resonance imaging, positron emission tomography/computed tomography, and real-time elastography in the differentiation of benign and malignant salivary gland tumors: a meta-analysisPublication date: Available online 27 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Xiangpan Kong, Hua Li, Zhengxue HanObjectiveThe objective of this study was to assess the diagnostic properties of ultrasonography, computed tomography (CT), magnetic resonance imaging (MRI), positron emission tomography/computed tomography (PET/CT), and real-time elastography (RTE) in distinguishing between benign and m
- Influence of phosphor plate–based radiographic image specifications on fractal analysis of alveolar bonePublication date: Available online 27 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Nicolly Oliveira-Santos, Mariane Michels, Deborah Queiroz Freitas, Francisco Haiter-Neto, Matheus Lima OliveiraObjectiveThe aim of this study was to evaluate the influence of spatial resolution, bit depth, and enhancement filters on the fractal dimension (FD) of photostimulable phosphor (PSP) plate–based intraoral radiog
- Mandibular 3-dimensional finite element analysis for a patient with an aggressive form of craniofacial fibrous dysplasiaPublication date: Available online 25 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Takuya Kihara, Tomoko Ikawa, Yuko Shigeta, Shuji Shigemoto, Kazutoshi Nakaoka, Yoshiki Hamada, Takumi OgawaThe longitudinal change in mandibular volume and configuration was quantitatively evaluated in a patient with craniofacial fibrous dysplasia (FD). The influence of mechanical stress on the enlargement that is charac
- In reply to the letter to the editor (MS#TRIPLEO-D-19-00051) concerning “Changes of the condylar position after modified disc repositioning: a retrospective study based on magnetic resonance imaging”Publication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Xuzhuo Chen, Jisi Zheng
- Multiple adenomatoid odontogenic tumors in a patient with Schimmelpenning syndromePublication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Roberta Rayra Martins Chaves, Aécio Abner Campos Pinto Júnior, Carolina Cavaliéri Gomes, Wagner Henriques de Castro, Ricardo Santiago GomezSchimmelpenning syndrome (SS) is a congenital neurocutaneous disorder characterized by the presence of linear nevus sebaceous, ophthalmic, neurologic, skeletal, urologic, and cardiova
- Clinical and pathologic analysis of myopericytoma in the oral and maxillofacial regionPublication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Wu-tong Ju, Tong-chao Zhao, Ying Liu, Min-jun Dong, Li-zhen Wang, Jiang Li, Yi-ran Tan, Lai-ping ZhongObjectiveThe aim of this study was to analyze myopericytoma in the oral and maxillofacial region in terms of clinical appearance, diagnosis, treatment, and outcomes.Study DesignData on 5 new patients with myopericytoma i
- Response to Letters to the Editor regarding the editorial “Artificial intelligence, machine learning, and the human interface in medicine: is there a sweet spot for oral and maxillofacial radiology?”Publication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Aditya Tadinada
- Cyclooxygenase and CD147 expression in oral squamous cell carcinoma patient samples and cell linesPublication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Walaa Hamed Shaker Nasry, Haili Wang, Kathleen Jones, Marvin Tesch, Juan Carlos Rodriguez-Lecompte, Chelsea K. MartinObjectivesIn oral squamous cell carcinoma (OSCC), cyclooxygenases (COX-1 and COX-2) contribute to inflammation, and cluster of differentiation factor 147 (CD147) contributes to invasiveness, but their rela
- Response to Editorial “Artificial intelligence, machine learning, and the human interface in medicine: Is there a sweet spot for oral and maxillofacial radiology?”Publication date: Available online 14 June 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral RadiologyAuthor(s): Douglas K. Benn
- Immediate Manifestation of Ocular Decompression Retinopathy following Anterior Chamber ParacentesisOcular decompression retinopathy (ODR) is a complication of rapid lowering of intraocular pressure (IOP) resulting in hemorrhages in multiple retinal layers. We report a case of ODR that developed within minutes following anterior chamber paracentesis in an adult female with primary open-angle glaucoma. A 61-year-old Black woman with primary open-angle glaucoma presented with marked elevation of IOP (46 mm Hg in the right eye and 30 mm Hg in the
- Cardiac CT in the Preoperative Diagnostics of Neonates with Congenital Heart Disease: Radiation Dose Optimization by Omitting Test Bolus or Bolus TrackingPublication date: Available online 20 August 2019Source: Academic RadiologyAuthor(s): Philipp Schindler, Hans-Gerd Kehl, Moritz Wildgruber, Walter Heindel, Christoph SchülkeRationale and ObjectivesCongenital heart diseases (CHD) belong to the leading causes of infant mortality worldwide. Prognostic improvements result from multimodal therapy strategies leading to an increased demand for noninvasive imaging. The aim of the study was to further opt
- MRI Texture Analysis for Differentiating Nonfunctional Pancreatic Neuroendocrine Neoplasms From Solid Pseudopapillary Neoplasms of the PancreasPublication date: Available online 20 August 2019Source: Academic RadiologyAuthor(s): Xudong Li, Hui Zhu, Xiaohua Qian, Nan Chen, Xiaozhu LinRationale and ObjectivesTo evaluate the value of texture analysis on preoperative magnetic resonance imaging (MRI) for identifying nonfunctional pancreatic neuroendocrine neoplasms (NF-PNENs) and solid pseudopapillary neoplasms (SPNs).Materials and MethodsThis retrospective study included 119 patients who un
- Dynamic Contrast-Enhanced MRI Evaluation of Pathologic Complete Response in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer After HER2-Targeted TherapyPublication date: Available online 20 August 2019Source: Academic RadiologyAuthor(s): Laura Heacock, Alana Lewin, Abimbola Ayoola, Melanie Moccaldi, James S. Babb, Sungheon G. Kim, Linda MoyRationale and ObjectivesPathologic complete response (pCR) in patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer after HER2-targeted therapy correlates increased disease-free survival and decreased mastectomy rates. The aim of
- Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）.Condition: Esophageal Squamous Cell CarcinomaIntervention: Drug: Anlotinib Hydrochloride, Paclitaxel, cisplatinSponsors: Henan Cancer Hospital; Chia Tai Tianqing Pharmaceutical Group Co., Ltd.Not yet recruiting
- Inverse association between 1,5-anhydroglucitol and neonatal diabetic complicationsAbstract Purpose A glycemic control marker to predict neonatal diabetic complications is unavailable. We aimed to examine if 1,5-anhydroglucitol (1,5-AG) can predict neonatal complications in women with diabetes in pregnancy. Methods Prospective observational study from December 2011 to August 2013. We re
- Design by Anthropologists, a New Blog about Anthropology in PracticeNAPA is pleased to announce the launch of an informative and important monthly blog, Design by Anthropologists. The blog’s purpose is to chronicle current explorations in and developments around the interface of anthropology, design, user experience (UX) and research, usability research, and related endeavors. The monthly blog, written by anthropologists working in the field, will help capture current and ongoing developments in this coalescing
- Cancers, Vol. 11, Pages 1219: Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 RegulomeCancers, Vol. 11, Pages 1219: Hyper-Activation of STAT3 Sustains Progression of Non-Papillary Basal-Type Bladder Cancer via FOSL1 Regulome Cancers doi: 10.3390/cancers11091219 Authors: Gatta Melocchi Bugatti Missale Lonardi Zanetti Cristinelli Belotti Simeone Ronca Grillo Licini Bresciani Tardanico Chan Giurisato Calza Vermi Urothelial bladder cancer (UBC) are class
- Cancers, Vol. 11, Pages 1218: ADAM17: An Emerging Therapeutic Target for Lung CancerCancers, Vol. 11, Pages 1218: ADAM17: An Emerging Therapeutic Target for Lung Cancer Cancers doi: 10.3390/cancers11091218 Authors: Saad Rose-John Jenkins Lung cancer is the leading cause of cancer-related mortality, which histologically is classified into small-cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). NSCLC accounts for approximately 85% of all lung cancer diagnoses, with the majority of patients prese
- Cancers, Vol. 11, Pages 1216: Wnt Signaling Pathways in Keratinocyte CarcinomasCancers, Vol. 11, Pages 1216: Wnt Signaling Pathways in Keratinocyte Carcinomas Cancers doi: 10.3390/cancers11091216 Authors: Christopher M. R. Lang Chim Kei Chan Anthony Veltri Wen-Hui Lien The skin functions as a barrier between the organism and the surrounding environment. Direct exposure to external stimuli and the accumulation of genetic mutations may lead to abnormal cell growth, irreversible tissue damage and potentia
- Learning to detect lymphocytes in immunohistochemistry with deep learningPublication date: Available online 21 August 2019Source: Medical Image AnalysisAuthor(s): Zaneta Swiderska-Chadaj, Hans Pinckaers, Mart van Rijthoven, Maschenka Balkenhol, Margarita Melnikova, Oscar Geessink, Quirine Manson, Mark Sherman, Antonio Polonia, Jeremy Parry, Mustapha Abubakar, Geert Litjens, Jeroen van der Laak, Francesco CiompiAbstractThe immune system is of critical importance in the development of cancer. The evasion of destruction
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