Efficacy and clinical significance of omitting blue dye injection during sentinel lymph node biopsy before Mohs micrographic surgery for malignant melanoma of the lower extremities
Version of Record online: 28 July 2019
What's already known about this topic?
What does this study add?
- Sentinel lymph node biopsy (SLNB) is usually performed using a triple technique including lymphoscintigraphy, which involves the injection of a radiolabelled tracer, blue dye injection, and radioisotope detection using a gamma probe.
- Blue dye injection may cause pathological misinterpretation and obscure clinical margins.
What does this study add?
- Omitting the dye does not decrease diagnostic accuracy and is particularly advantageous for Mohs micrographic surgery (MMS) in melanomas with clinically indistinct tumour borders.
- SLNB without blue dye injection is feasible in MMS for melanoma.
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