WEDNESDAY, Aug. 21, 2019 -- Women with diagnosed diabetes are more likely than men to not take their medications as prescribed, according to an August data brief published by the U.S. Centers for Disease Control and Prevention National Center for...
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WEDNESDAY, Aug. 21, 2019 -- Chronic exposure to high levels of nitrogen dioxide (NO2) and carbon monoxide (CO) is associated with an increased risk for age-related macular degeneration (AMD) in a population in Taiwan, according to a study published...
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WEDNESDAY, Aug. 21, 2019 -- Among former smokers, the prevalence of depression and substance use has increased over time, according to a study published online Aug. 20 in the American Journal of Preventive Medicine. Keely Cheslack-Postava, Ph.D.,...
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WEDNESDAY, Aug. 21, 2019 -- There appears to be a correlation for high and increasing blood pressure (BP) from early adulthood and into midlife with white matter hyperintensity volume (WMHV) and smaller brain volumes at age 69 to 71 years, according...
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WEDNESDAY, Aug. 21, 2019 -- Using buprenorphine to treat opioid use disorder (OUD) may increase adherence to treatments for other chronic conditions, according to a study published in the September issue of Medical Care. Hsien-Yen Chang, Ph.D., from...
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WEDNESDAY, Aug. 21, 2019 -- Quitting smoking is associated with reduced rates of incident cardiovascular disease (CVD) within five years compared with current smoking, although the risks remain elevated after five years compared with never smoking,...
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WEDNESDAY, Aug. 21, 2019 -- A virtual reality (VR) program reduces pain in hospitalized patients compared to a television program control, according to a study published online Aug. 14 in PLOS ONE. Brennan Spiegel, M.D., of the Cedars-Sinai Health...
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WEDNESDAY, Aug. 21, 2019 -- Postmenopausal women with normoglycemia with a first-degree family history of diabetes (FHD) have elevated bone mineral density (BMD), according to a study published online Aug. 19 in Menopause. Lijuan Yang, M.D., from...
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WEDNESDAY, Aug. 21, 2019 -- Pre-emergency department evaluation on a mobile stroke unit (MSU) can speed access to intraarterial thrombectomy (IAT) compared with standard management by emergency medical services (EMS), according to a study published...
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WEDNESDAY, Aug. 21, 2019 -- A hospital's move to entirely single-patient rooms was associated with reductions in multidrug-resistant organism colonization, according to a study published online Aug. 19 in JAMA Internal Medicine. Emily G. McDonald,...
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Related ArticlesSwallowing behaviours and feeding environment in relation to communication development from early infancy to 6 years of age: a scoping review protocol. BMJ Open. 2019 Aug 18;9(8):e028850 Authors: Flowers H, Bérubé D, Ebrahimipour M, Perrier MF, Moloci S, Skoretz S Abstract INTRODUCTION: Understanding the influences of early swallowing function and feeding environment on the development of communication will enhance prevention and intervention...
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Related ArticlesUltrasound-Guided Injection of Botulinum Toxin for Cricopharyngeal Dysphagia. Am J Phys Med Rehabil. 2018 10;97(10):e102-e103 Authors: Wang YC, Shyu SG, Wu CH, Wang TG PMID: 29757765 [PubMed - indexed for MEDLINE]
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Related ArticlesEpstein-Barr Virus-Associated With Lymphoepithelial Carcinoma: A Rare Tumor of the Larynx. Clin Med Insights Ear Nose Throat. 2019;12:1179550619865551 Authors: Monteiro F, Baldaia H, Ribeiro L, Sousa M, Oliveira P, Ferreira E, de Almeida MG, Condé A Abstract Lymphoepithelial carcinoma of the larynx is a rare tumor, as this histological entity is mostly diagnosed in nasopharynx. However, it may be present in other non-nasopharyngeal sites...
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Classical intermolecular potentials typically require an extensive parametrization procedure for any new compound considered. To do away with prior parametrization, we propose a combination of physics-based potentials with machine learning (ML), coined IPML, which is transferable across small neutral organic and biologically relevant molecules. ML models provide on-the-fly predictions for environment-dependent local atomic properties: electrostatic multipole coefficients (significant error reduction...
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We introduce a representation of any atom in any chemical environment for the automatized generation of universal kernel ridge regression-based quantum machine learning (QML) models of electronic properties, trained throughout chemical compound space. The representation is based on Gaussian distribution functions, scaled by power laws and explicitly accounting for structural as well as elemental degrees of freedom. The elemental components help us to lower the QML model's learning curve, and, through...
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A set of molecular descriptors whose length is independent of molecular size is developed for machine learning models that target thermodynamic and electronic properties of molecules. These features are evaluated by monitoring performance of kernel ridge regression models on well-studied data sets of small organic molecules. The features include connectivity counts, which require only the bonding pattern of the molecule, and encoded distances, which summarize distances between both bonded and non-bonded...
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Generalized Density-Functional Tight-Binding Repulsive Potentials from Unsupervised Machine Learning
We combine the approximate density-functional tight-binding (DFTB) method with unsupervised machine learning. This allows us to improve transferability and accuracy, make use of large quantum chemical data sets for the parametrization, and efficiently automatize the parametrization process of DFTB. For this purpose, generalized pair-potentials are introduced, where the chemical environment is included during the learning process, leading to more specific effective two-body potentials. We train on...
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A survey of the contributions to the Special Topic on Data-enabled Theoretical Chemistry is given, including a glossary of relevant machine learning terms.
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Dissipation mechanisms in a broad spectrum of physical systems and media attracted great interest among fundamental scientific and applied communities. Understanding the origin of various energy dissipation (non-contact friction) mechanism is still a wide-open problem. The frictional nature of layered systems, such as those hosting charge density wave (CDW) and topologically protected surface state, awaits to be investigated. Regarding CDW, I investigated non-contact energy dissipation on 1T-TaS2...
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The formation of a functional vasculature is a crucial step during vertebrate development. In order to transport blood, the initial vascular sprouts interconnect and lumenize to form a patent vascular network. One of the main morphogenetic mechanisms to form interconnected lumens is transcellular lumen formation, where the lumen pushes through a single cell. During transcellular lumen formation, the apical membrane surface is extended in a highly dynamic fashion and it is not known, which trafficking...
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Aging is a physiological process associated with decreased mental abilities but also declining muscle function, posture and balance. Consequently, every third elderly person above 60 falls at least once per year, greatly affecting quality of life and independence. Body posture, gait and balance can be improved by physical activity. However, it is not at all understood why and how exercise improves balance function because the neuropathological mechanisms underlying age-associated balance disorders...
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Hepatitis B virus (HBV) is a blood-borne human pathogen of worldwide importance. It replicates in the hepatocytes in the liver and causes a disease known as Hepatitis B. Approximately 3% of the world population are chronically infected with HBV. Chronic Hepatitis B (CHB) is the number one cause of hepatocellular carcinoma in the world leading to close to 1 million deaths every year. Treatment options are limited and none of them are curative due to persistence of the viral covalently closed circular...
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Time difference of arrival (TDOA) positioning is one of the widely applied techniques for locating an emitting source. Unfortunately, synchronization clock bias and random sensor location perturbations are kno...
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This paper considers regression tasks involving high-dimensional multivariate processes whose structure is dependent on some known graph topology. We put forth a new definition of time-vertex wide-sense statio...
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Publication date: Available online 20 August 2019Source: European Journal of Surgical OncologyAuthor(s): Ashok R. Shaha, R. Michael Tuttle
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Publication date: Available online 20 August 2019Source: European Journal of Surgical OncologyAuthor(s): Wei Zhang, Cong Tan, Midie Xu, Xiaohua WuAbstractObjectiveThe aim of this study was to investigate the clinicopathological characteristics of appendiceal mucinous neoplasm that had been preoperatively misdiagnosed as a mucinous ovarian tumor and to discuss the clinical impacts of misdiagnosis.MethodsSeventy-eight patients with a final pathologic diagnosis of appendiceal mucinous neoplasm during...
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Goji berry, Lycium barbarum, has been widely used in traditional Chinese medicine (TCM), but its properties have not been studied until recently. The fruit is a major source of zeaxanthin dipalmitate (ZD), a xanthophyll carotenoid shown to benefit the liver. Liver disease is one of the most prevalent diseases in the world. Some conditions, such as chronic hepatitis B virus, liver cirrhosis, and hepatocellular carcinoma, remain incurable. Managing them can constitute an economic burden for patients...
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The aim of the study is to explore the protective effect of new gelatin (NG, Xin’ejiao in China) on hematopoietic injury caused by chemotherapy. Zebrafish, at 48 hours post fertilization (hpf), was treated with different chemotherapeutic drugs to establish the zebrafish hematopoietic damage model with reduced thrombocytes and erythrocytes. The protecting effects of NG on the thrombocytes and erythrocytes were observed, respectively, on zebrafish models. Then, the RT-PCR method was used to detect...
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In England, the bursary for student nurses was removed in 2017 when they also became liable to pay tuition fees.1 The aim was to reduce the cap on student nurse numbers. While the cynics among us may think the real reason was to reduce the £1 billion spent on non-medical pre-registration education each year, the Council of Deans of Health (CoDH) supported the move. They argued that in addition to removing the cap on numbers the change in financing nurse education would leave student nurses better...
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Objectives: This study investigated the effect of training backward and forward voice focus adjustments on oral-nasal balance in speech and singing in typical speakers. Methods: Twenty participants (10M/10F) aged 24.25 (SD 3.73) years read phonetically balanced, nasal and oral speech stimuli, and sang a song in both forward and backward voice focus conditions. A Nasometer 6450 was used to obtain nasalance scores in the different conditions. Results: Results indicated that forward voice focus resulted...
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Objective: The purpose of this research was to conduct an exploratory study of the performance of Brazilian children on the Rapid Automatic Naming (RAN) test, examining schooling effects of schooling and associations with reading speed, comprehension, and reading level for each of the RAN subtests of colour, numbers, letters, and objects. Methods: Participants were 97 children, aged 7–11 years, enrolled in the first to fifth grade of elementary public education. Results: The findings indicated a...
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