Abstract The embryo of the purple sea urchin has been a fruitful model for the study of developmental gene regulatory networks. For similar reasons, the feeding sea urchin larva provides a gene regulatory model to investigate immune interactions at the gut epithelium. Here we describe what is known of the gut structure and immune cells of the sea urchin larva, and the cellular and gene expression response of the larva to gut-associated immune challenge. As a focused example of...
1m
The updated definition of central nervous system infarction is brain, spinal cord, or retinal cell death attributable to ischemia in a defined vascular territory, based on neuropathological, neuroimaging, and/or clinical evidence of focal ischemic injury with symptoms persisting ≥24 h or until death, and other etiologies excluded [1]. Stroke is the brain equivalent of a heart attack [2]. In Caucasian populations approximately 80% of all strokes are ischemic, 10%-15% intracerebral hemorrhage (ICH),...
10h
Idiopathic Parkinson's Disease (IPH) is the second most common neurodegenerative disease with tremors, motor findings (rigidity, bradykinesia, etc.) and cognitive impairments, in the geriatric population after Alzheimer's Disease (AD), affecting approximately 1–2% of the population over 60 years of age [1–8]. Although the etiopathogenesis of the loss of selective dopamine neurons remains unclear, increasing evidence suggests that oxidative stress, mitochondrial dysfunction, and apoptosis associated...
10h
Telemedicine for the management of AIS is being increasingly used to improve stroke care and to deliver stroke expertise to physicians and patients in underserved areas. [1–3]. The number and extent of telestroke networks and the implementation of telestroke into routine practice is rapidly growing in the United States and throughout the world [2,4]. Recently, thrombectomy alone or after administration of intravenous tissue plasminogen activator (i.v. t-PA), has proven to be effective for the treatment...
10h
Orthodontic treatment combined with a maxillomandibular advancement (MMA) can be an effective option for patients who need not only corrected occlusion but also facial rejuvenation. In this case series, two pa...
10h
Objective: Present study was aimed to precisely evaluate the angio-architectures in patients with asymptomatic moyamoya disease (MMD) by comparing with those with hemorrhagic stroke. Methods: This study used the data set of cerebral angiography in Asymptomatic Moyamoya Registry (AMORE) Study and Japan Adult Moyamoya (JAM) Trial at enrollment. The development of 3 subtypes of collateral vessels, including lenticulostriate, thalamic, and choroidal anastomosis, was evaluated on cerebral angiography.
10h
Leukemia, Published online: 27 August 2019; doi:10.1038/s41375-019-0554-1Obinutuzumab plus fludarabine and cyclophosphamide in previously untreated, fit patients with chronic lymphocytic leukemia: a subgroup analysis of the GREEN study
10h
Leukemia, Published online: 27 August 2019; doi:10.1038/s41375-019-0561-2Relapsed refractory multiple myeloma: a comprehensive overview
10h
Leukemia, Published online: 27 August 2019; doi:10.1038/s41375-019-0552-3Evaluation of ERK as a therapeutic target in acute myelogenous leukemia
10h
Leukemia, Published online: 27 August 2019; doi:10.1038/s41375-019-0562-1Chronic myeloid leukemia: the concepts of resistance and persistence and the relationship with the BCR-ABL1 transcript type
10h
At the European Society for Vascular Surgery (ESVS) Annual Meeting in Budapest, Hungary, in September 2013, a landmark meeting was held that charted a new course of collaboration among the major Vascular Surgery Societies. Representatives from the ESVS, the Society for Vascular Surgery (SVS), and the World Federation of Vascular Societies (WFVS) met and agreed that the TransAtlantic Societal Consensus process no longer met the needs of defining standards of vascular care.1 The group unanimously agreed...
10h
In this study, the aim was to investigate the potential for single muscle fibre contractility (SMFC) testing to detect the extent of reperfusion injury following various reperfusion periods. The hypothesis was that force generated by muscle fibres will correlate inversely with the extent of reperfusion injury.
10h
Post-hospital syndrome (PHS) is an acquired, transient period of health vulnerability that follows hospital admission for acute illness. It is characterized by physiologic deconditioning secondary to stressors from disruption in circadian rhythm, depletion of nutritional reserve, and pain or discomfort associated with hospitalization. PHS is reported as an independent risk factor for readmission and adverse postoperative outcomes. The aim of this study was to investigate whether PHS affects outcomes...
10h
Endovascular abdominal aortic aneurysm repair (EVAR) is commonly used to treat abdominal aortic aneurysm (AAA). However, the incidence of long-term complications and the need for re-interventions after EVAR remains a concern. Newer generation stent grafts have encouraging short and mid-term outcomes, but thorough analysis of their long-term performance is necessary.
10h
To gather consensus among European educators about technical procedures that should be included in a future simulation based curriculum in vascular surgery.
10h
News items of interest to the vascular surgeon must be received at least 8 weeks before the desired month of publication. Announcements published at no charge include those received from a sponsoring society of this Journal, those courses and conferences sponsored by state, regional, national, or international vascular surgical organizations, and university-sponsored continuing medical education courses. Send applicable events to Andrew O’Brien, Journal Manager, at a.obrien@elsevier.com. All other...
10h
There are limited data evaluating the impact of preoperative albumin levels in patients undergoing vascular procedures. This study evaluated the relationship of preoperative albumin levels with outcome after lower extremity (LE) vascular procedures for peripheral artery disease (PAD).
10h
Carotid artery stenting (CAS) in patients with hostile neck anatomy (prior radiation therapy [XRT] and carotid endarterectomy [CEA]) is safe and effective, but concern remains for higher restenosis and differences in postoperative neurologic events. Our objective was to determine whether periprocedural and long-term outcomes of CAS performed in patients who have had prior XRT or CEA are comparable to those of patients with normal neck anatomy (NL).
10h
Peri-procedural ischaemic brain lesions on diffusion weighted imaging (DWI) after carotid endarterectomy (CEA) and carotid artery stenting (CAS) have been related to a higher chance of recurrent cerebrovascular events. This systematic review provides an overview of patient characteristics associated with increased risk of new DWI lesions.
10h
Surgical revascularisation to accomplish limb salvage remains preferable in some patients with chronic limb threatening ischaemia (CLTI). The aim of this study was to evaluate the effectiveness and safety of ultrasound guided lower extremity nerve blockade (UGNB) in infragenicular bypass surgery (IGBS).
10h
Aortic graft infection (AGI) is a disastrous complication with an incidence of 0.2–6% in operated patients. With little or no high quality evidence, the best treatment option remains unclear. Therefore, the literature on the management of open abdominal AGI was systematically reviewed to determine optimal treatment.
10h
Communications regarding original articles and editorial management should be addressed to Peter Gloviczki, MD, and Peter F. Lawrence, MD, Editors, Journal of Vascular Surgery, 9400 W. Higgins Road, Suite 315, Rosemont IL 60018; telephone: 312-334-2355; fax: 312-334-2320; e-mail: JVASCSURG@vascularsociety.org. Information for authors appears in the January and July issues, at www.jvascsurg.org, and at jvs.editorialmanager.com. Authors should consult this document before submitting manuscripts to...
10h
Informed debate about optimal carotid endarterectomy (CEA) use for severe stenosis requires contemporary assessment of long-term procedural stroke risk reduction with periprocedural risk, and long-term outcome data, particularly for asymptomatic (ASX) stenosis, are lacking. In this study, we report long-term stroke and death risk after CEA in a large integrated health care system.
10h
The Wound Ischemia foot Infection (WIfI) classification has gained widespread acceptance in the vascular community as a method of categorizing disease severity in patients with chronic limb-threatening ischemia (CLTI). The original WIfI system is based on a Delphi consensus model, which relies on an iterative process of consensus amongst experts, but is not necessarily data driven. Twelve experts were selected in the formation of the initial WIfI model. The WIfI classification was initially developed...
10h
Diabetes has been shown to be associated with increased risk of postoperative complications after lower extremity bypass (LEB), although it is unclear whether short-term glucose control affects outcomes. This study aimed to assess the impact of perioperative hemoglobin A1c (HbA1c) levels on short- and long-term results after LEB.
10h
Upper extremity and neck access is increasingly being used for complex endovascular aortic repairs. We sought to compare perioperative stroke and other complications of (1) arm/neck with femoral/iliac access (AN) vs femoral/iliac access alone (FI), (2) right- vs left-sided AN, and (3) arm vs neck access sites.
10h
Nature Reviews Clinical Oncology, Published online: 27 August 2019; doi:10.1038/s41571-019-0270-9WEE1 kinase inhibitor shows promise
10h
Researchers from the Polytechnic University of Milan and the University Hospital of Basel have developed a microfluidic chip containing cartilage, which can be subjected to mechanical stress. The procedure mimics the conditions of osteoarthritis and could help in developing new treatments. Osteoarthritis is relatively common among people over 60, with 20% of women and 10% of men suffering its effects at this age. However, perhaps surprisingly, there are no drugs available that can...
11h
Recently I visited a lady at her home who was a palliative care patient. She was seated on the couch in the living room with a turban on her head and a look of anxiety and depression. Her husband was quiet during the entire visit. He was seated in a chair next to the couch […]Find jobs at Careers by KevinMD.com. Search thousands of physician, PA, NP, and CRNA jobs now. Learn more. (Source: Kevin, M.D. - Medical Weblog)
11h
Pre-oxygenate, evaluate for LEMONS and position a patient of any size correctly to help secure an airway
11h
Not billing for EMS patient transport leaves money in the pockets of insurance companies and government programs created to pay for ambulance transport
13h
Ambulance services cannot afford to feed the billing department incomplete, inaccurate or misrepresented information
13h
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου