Community paramedicine communication with patients, their family members and the local crews can eliminate obstacles and improve patient care for bariatric patients
15h
In this episode, our co-hosts discuss the challenges that come with assisting bariatric patients, including logistics, equipment needs and provider attitudes
15h
Not billing for EMS patient transport leaves money in the pockets of insurance companies and government programs created to pay for ambulance transport
13h
Climbing the ranks of EMS often fails to prepare new chiefs to discuss financial issues with local elected and appointed officials
13h
We reported a case with tension pneumoperitoneum while being on high-frequency oscillatory ventilation.
11h
This protocol is designed to assess the viability of Drosophila at every developmental stage, from embryo to adult. The method can be used to determine and compare the viability of different genotypes or growth conditions.
11h
Mechanical forces are important for controlling cell migration. This protocol demonstrates the use of elastic hydrogels that can be deformed using a glass micropipette and a micromanipulator to stimulate cells with a local stiffness gradient to elicit changes in cell structure and migration.
11h
In this study, we enhanced the data analysis capabilities of the DARTS experiment by monitoring the changes in protein stability and estimating the affinity of protein-ligand interactions. The interactions can be plotted into two curves: a proteolytic curve and a dose-dependence curve. We have used mTOR-rapamycin interaction as an exemplary case.
12h
We describe a protocol utilizing fluorescence in situ hybridization (FISH) to visualize multiple herpesviral RNAs within lytically infected human cells, either in suspension or adherent. This protocol includes quantification of fluorescence producing a nucleocytoplasmic ratio and can be extended for simultaneous visualization of host and viral proteins with immunofluorescence (IF).
12h
This protocol introduces a standard laboratory operating procedure for diagnostic testing of lyssavirus antigens in bats in Taiwan.
13h
Single-fiber recording is an effective electrophysiological technique that is applicable to the central and peripheral nervous systems. Along with the preparation of intact DRG with the attached sciatic nerve, the mechanism of conduction failure is examined. Both protocols improve the understanding of the peripheral nervous system's relationship with pain.
13h
Emission spectroscopy techniques have traditionally been used to analyze inherently random lightning arcs occurring in nature. In this paper, a method developed to obtain the emission spectroscopy from reproducible lightning arcs generated within a laboratory environment is described.
14h
Nature Reviews Genetics, Published online: 27 August 2019; doi:10.1038/s41576-019-0156-9In a recent declaration, 21 European countries committed to sharing data on at least 1 million human genomes by 2022. This Roadmap emphasizes the challenges of genomic data sharing across borders and how European research infrastructures can support the rapid implementation of transnational access to genomic data.
11h
by Hiroyuki Irie, Io Yamamoto, Yusuke Tarumoto, Sanki Tashiro, Kurt W. Runge, Fuyuki Ishikawa Genomic rearrangements (gross chromosomal rearrangements, GCRs) threatens genome integrity and cause cell death or tumor formation. At the terminus of linear chromosomes, a telomere-binding protein complex, called shelterin, ensures chromosome stability by preventing chromosome end-to-end fusions and regulating telomere length homeostasis. As such, shelterin-mediated telomere functions play a pivotal...
12h
Author: Wojcik, Cezary MD, PhD; Shapiro, Michael D. DO, MCR Page: 709-711
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Author: Naeije, Robert MD; Chin, Kelly MD Page: 712-714
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Author: Kontis, Vasilis PhD; Cobb, Laura K. DrPH; Mathers, Colin D. PhD; Frieden, Thomas R. MD; Ezzati, Majid PhD; Danaei, Goodarz ScD Page: 715-725
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Author: Colantonio, Lisandro D. MD, PhD; Muntner, Paul PhD Page: 726-728
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Author: Fu, Qi MD, PhD; Shibata, Shigeki MD, PhD; Hastings, Jeffrey L. MD; Platts, Steven H. PhD; Hamilton, Douglas M. MD; Bungo, Michael W. MD; Stenger, Michael B. PhD; Ribeiro, Christine JD, MS; Adams-Huet, Beverley MS; Levine, Benjamin D. MD Page: 729-738
12h
Author: Mahaffey, Kenneth W. MD; Jardine, Meg J. PhD; Bompoint, Severine BSc(stats); Cannon, Christopher P. MD; Neal, Bruce MB ChB, PhD; Heerspink, Hiddo J.L. PharmD, PhD; Charytan, David M. MD, MSc; Edwards, Robert MPH; Agarwal, Rajiv MD; Bakris, George MD; Bull, Scott PharmD; Capuano, George PhD; de Zeeuw, Dick MD, PhD; Greene, Tom PhD; Levin, Adeera MD; Pollock, Carol MBBS, PhD; Sun, Tao PhD; Wheeler, David C. MD; Yavin, Yshai MBChB; Zhang, Hong MD,...
12h
Author: Li, Yulin PhD; Chen, Boya MS; Yang, Xinying MS; Zhang, Congcong PhD; Jiao, Yao BA; Li, Ping MD; Liu, Yan PhD; Li, Zhenya PhD; Qiao, Bokang MS; Bond Lau, Wayne MD; Ma, Xin-liang MD, PhD; Du, Jie PhD Page: 751-764
12h
Author: Zaleta-Rivera, Kathia PhD; Dainis, Alexandra PhD; Ribeiro, Alexandre J.S. PhD; Cordero, Pablo PhD; Rubio, Gabriel MD; Shang, Ching PhD; Liu, Jing MD; Finsterbach, Thomas PhD; Parikh, Victoria N. MD; Sutton, Shirley MS; Seo, Kinya PhD; Sinha, Nikita BS; Jain, Nikhil MD; Huang, Yong MD; Hajjar, Roger J. MD, PhD; Kay, Mark A. MD, PhD; Szczesna-Cordary, Danuta PhD; Pruitt, Beth L. PhD; Wheeler, Matthew T. MD, PhD ,*; Ashley, Euan A. MB ChB, DPhil ,,*...
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Author: Packer, Milton MD; Grayburn, Paul A. MD Page: 779-789
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Author: Smith, Blake G. MD; Kalehoff, Jonathan MD; Kay, G. Neal MD Page: 793-795
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Author: Larsson, Susanna C. PhD; Markus, Hugh S. MD Page: 796-798
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Author: Peran, David MSc; Vesela, Katarina MD; Franek, Ondrej MD Page: e510
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Author: Perman, Sarah M. MD, MSCE; Shelton, Shelby K. MPH; Knoepke, Christopher PhD, MSW; Rappaport, Kathryn MD; Matlock, Daniel D. MD, MPH; Adelgais, Kathleen MD, MPH; Havranek, Edward P. MD; Daugherty, Stacie L. MD, MSPH Page: e511-e512
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Author: Xie, Jian MD; Jiang, Mingyang MD; Li, Lang MD, PhD Page: e513-e514
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Author: Grandi, Sonia M. MSc; Platt, Robert W. PhD Page: e515-e516
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Author: Geocadin, Romergryko G. MD, Chair; Callaway, Clifton W. MD, PhD, FAHA; Fink, Ericka L. MD, MS; Golan, Eyal MD; Greer, David M. MD, MA, FAHA; Ko, Nerissa U. MD, MAS; Lang, Eddy MD; Licht, Daniel J. MD; Marino, Bradley S. MD, MPP, MSCE, FAHA; McNair, Norma D. PhD, RN, FAHA; Peberdy, Mary Ann MD, FAHA; Perman, Sarah M. MD, MSCE, FAHA; Sims, Daniel B. MD, FAHA; Soar, Jasmeet MA, MB, BChir; Sandroni, Claudio MD, Vice Chair; On behalf of the American...
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Author: Page: e543
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Author: Page: e544
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[ Advance Publication ] [ Title ] Characteristics of Cerebral Aneurysms in Japan [ Author ] Fusao IKAWA,Toshikazu HIDAKA,Michitsura YOSHIYAMA,Hideo OHBA,Shingo MATSUDA,Iori OZONO,Koji IIHARA,Hiroyuki KINOUCHI,Kazuhiko NOZAKI,Yoko KATO,Akio MORITA,Nobuaki MICHIHATA,Hideo YASUNAGA,Kaoru KURISU [ Advance Pub. date ] 2019-08-28 [ DOI ] https://doi.org/10.2176/nmc.ra.2019-0099
12h
Nature Communications, Published online: 27 August 2019; doi:10.1038/s41467-019-11865-8While the crisis of statistics has made it to the headlines, that of mathematical modelling hasn’t. Something can be learned comparing the two, and looking at other instances of production of numbers.Sociology of quantification and post-normal science can help.
12h
Nature Communications, Published online: 27 August 2019; doi:10.1038/s41467-019-11665-0Hair follicles (HFs) are sensitive to chemotherapy but recover from quiescent HF stem cells, although sometimes chemotherapy results in permanent loss. Here, Kim et al. establish a model of permanent chemotherapy-induced alopecia to uncover the underlying mechanisms depleting human HF stem cells.
12h
Nature Communications, Published online: 27 August 2019; doi:10.1038/s41467-019-11886-3Owing to its driven-dissipative nature, and its solid-state environment, a resonantly driven polariton condensate can be accompanied by an incoherent reservoir of excitons. Stepanov et al. demonstrate that this situation strongly modifies the spectrum of collective excitations, which determines many quantum hydrodynamic features in a polariton fluid.
12h
Nature Communications, Published online: 27 August 2019; doi:10.1038/s41467-019-11754-0Here, the authors show that Zika virus (ZIKV) infection induces Th1-like Tfh cells that depend on T-bet for their development and are essential for class switching of ZIKV-specific IgG2c antibodies and maintenance of long-term neutralizing antibody responses.
12h
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