Abstract Uranium wastewater treatment has been performed by adsorption method using Mg(OH)2-impregnated activated carbon. Research purposes are to determine (i) uptake capacity of the adsorption isotherm of uranium in Mg(OH)2-impregnated activated carbon, (ii) mathematical correlation of uranium (VI) adsorption rate, and (iii) effect of the impregnation ratio of adsorbent to uranium removal efficiency. Adsorbent was synthesized through several stages, i.e., pyrolysis of coconut...
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Related ArticlesSpontaneous intracranial hypotension in a patient with systemic lupus erythematosus. Radiol Case Rep. 2019 Oct;14(10):1188-1192 Authors: Cohen-Addad DI, Efendizade A, Grigorian A, Hewitt K, Velayudhan V Abstract Spontaneous intracranial hypotension (SIH) associated with cerebrospinal fluid leak classically presents with postural headache. It is most commonly caused by the spontaneous dehiscence of a meningeal diverticulum or as a consequence...
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Publication date: Available online 20 August 2019Source: Magnetic Resonance ImagingAuthor(s): Kai Jiang, Hui Tang, Prasanna K. Mishra, Slobodan I. Macura, Lilach O. LermanAbstractPurposeTo propose a rapid multi-slice T1 measurement method using time-resolved imaging of contrast kinetics (TRICKS) and a semi-automated image processing algorithm for comprehensive assessment murine kidney function using dynamic contrast-enhanced MRI (DCE-MRI).MethodsA multi-slice TRICKS sampling scheme was implemented...
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Aging is characterized by a gradual deterioration in proteome. However, how protein dynamics that changes with normal aging and in disease is less well understood. Here, we profiled the snapshots of aging proteome in Drosophila, from head and muscle tissues of post-mitotic somatic cells, and the testis of mitotically-active cells. Our data demonstrated that dysregulation of proteome homeostasis, or proteostasis, might be a common feature associated with age. We further used pulsed metabolic stable...
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Aging is characterized by a gradual deterioration in proteome. However, how protein dynamics that changes with normal aging and in disease is less well understood. Here, we profiled the snapshots of aging proteome in Drosophila, from head and muscle tissues of post-mitotic somatic cells, and the testis of mitotically-active cells. Our data demonstrated that dysregulation of proteome homeostasis, or proteostasis, might be a common feature associated with age. We further used pulsed metabolic stable...
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As the Global Medical Device Industry Manager at MathWorks, Arvind Ananthan has immense experience working with medical device engineers, academic researchers, and regulatory authorities. Having a background in signal processing and electrical engineering, Arvind joined Mathworks 15 years ago as a technical sales engineer working with embedded systems before moving into his current role, where he identifies and addresses challenges faced by the medical device industry. We recently had the...
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Electronegative low-density lipoprotein (LDL(-)) has been found in the plasma of familial hypercholesterolemia and acute myocardial infarction and has been implicated in atherosclerosis and cardiovascular disease. However, less is known about the involvement of LDL(-) in atherosclerosis-related inflammation. This study aims at investigating the inducibility of LDL(-) by atherogenic diet in rabbits and at exploring the proinflammatory potential of the diet-induced LDL(-) in macrophages. Rabbits were...
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Publication date: Available online 21 August 2019Source: Medical Image AnalysisAuthor(s): Zaneta Swiderska-Chadaj, Hans Pinckaers, Mart van Rijthoven, Maschenka Balkenhol, Margarita Melnikova, Oscar Geessink, Quirine Manson, Mark Sherman, Antonio Polonia, Jeremy Parry, Mustapha Abubakar, Geert Litjens, Jeroen van der Laak, Francesco CiompiAbstractThe immune system is of critical importance in the development of cancer. The evasion of destruction by the immune system is one of the emerging hallmarks...
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NASHVILLE, TN – In an effort to provide much needed peace and quiet for the medical staff, Unit 4G at Nashville Memorial Hospital has extended its quiet hours, which will now take place between 3 PM and 2:59 PM. “Patients, nurses, and other medical staff really took a liking to the 3 PM to 4 PM quiet time we installed last year,” explained 4G Unit Director Nurse Dolly Rebecca. “The lights were turned down, everyone spoke at a whisper if at all, people paused and caught their breaths,...
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Purpose While general guidelines (such as CONSORT or CERT) exist to enhance the reporting of exercise interventions in the field of exercise science, there is inadequate detail facilitating the standardized reporting of resistance training adherence in the oncology setting. The purpose of this study was to apply a novel method to report resistance training dose, adherence and tolerance in patients with cancer. Methods A total of 47 prostate cancer patients (70.1 ± 8.9 yrs, body mass index,...
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Purpose This study determined associations between diet quality measured by the Healthy Eating Index (HEI)-2015, physical performance, and successful selection following a U.S. Army Special Forces Assessment and Selection (SFAS) course characterized by arduous cognitive and physical demands. Methods HEI-2015 scores were calculated from usual diet assessed with a Block food frequency questionnaire among 782 Soldiers attending SFAS. Differences in HEI-2015 scores according to demographics and...
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Purpose i. To develop an automated measurement technique for the assessment of both the form and intensity of physical activity undertaken by children during play. ii. To profile the varying activity across a cohort of children using a multivariate analysis of their movement patterns. Methods Ankle-worn accelerometers were used to record 40-minutes of activity during a school recess, for 24 children over 5 consecutive days. Activity events of 1.1 s duration were identified within the acceleration...
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Nine jurisdictions in the US now allow physician-assisted dying. But an overly complicated process plus lack of physician training poses formidable obstacles to patients who choose this option.Medscape Medical News (Source: Medscape Hematology-Oncology Headlines)
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Microbial Drug Resistance, Ahead of Print.
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Microorganisms, Vol. 7, Pages 275: Plant Tissue Localization and Morphological Conversion of Azospirillum brasilense upon Initial Interaction with Allium cepa L. Microorganisms doi: 10.3390/microorganisms7090275 Authors: Hong Orikasa Sakamoto Ohwada The genus Azospirillum is recognized as plant growth-promoting bacteria that exert beneficial effects on the host plant and is morphologically converted into cyst-like cells (i.e., c-form) in association with poly-β-hydroxybutyrate...
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Microorganisms, Vol. 7, Pages 279: Microbiota and Immune-Mediated Skin Diseases—An Overview Microorganisms doi: 10.3390/microorganisms7090279 Authors: Adrian Catinean Maria Adriana Neag Andrei Otto Mitre Corina Ioana Bocsan Anca Dana Buzoianu In recent years, increased attention has been paid to the relationship between microbiota and various diseases, especially immune-mediated diseases. Because conventional therapy for many autoimmune diseases is limited both in efficacy...
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Microorganisms, Vol. 7, Pages 280: Disinfectant Susceptibility of Biofilm Formed by Listeria monocytogenes under Selected Environmental Conditions Microorganisms doi: 10.3390/microorganisms7090280 Authors: Krzysztof Skowron Ewa Wałecka-Zacharska Katarzyna Grudlewska Piotr Gajewski Natalia Wiktorczyk Magdalena Wietlicka-Piszcz Andżelika Dudek Karolina Jadwiga Skowron Eugenia Gospodarek-Komkowska Listeria monocytogenes is a one of the most important food-borne pathogens....
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Microorganisms, Vol. 7, Pages 277: Infections Due to Multidrug-Resistant Bacteria in Oncological Patients: Insights from a Five-Year Epidemiological and Clinical Analysis Microorganisms doi: 10.3390/microorganisms7090277 Authors: Eleni Isidora A. Perdikouri Kostoula Arvaniti Dimitrios Lathyris Fani Apostolidou Kiouti Eleni Siskou Anna Bettina Haidich Christos Papandreou Bacterial infections are frequent complications in cancer patients. Among them, those caused by multidrug-resistant...
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Microorganisms, Vol. 7, Pages 278: Chloramphenicol Resurrected: A Journey from Antibiotic Resistance in Eye Infections to Biofilm and Ocular Microbiota Microorganisms doi: 10.3390/microorganisms7090278 Authors: Lorenzo The advent of multidrug resistance among pathogenic bacteria is devastating the worth of antibiotics and changing the way of their administration, as well as the approach to use new or old drugs. The crisis of antimicrobial resistance is also due to the unavailability...
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Microorganisms, Vol. 7, Pages 276: Development and Validation of Shiga Toxin-Producing Escherichia coli Immunodiagnostic Assay Microorganisms doi: 10.3390/microorganisms7090276 Authors: Miriam A. Silva Anna Raquel R. Santos Leticia B. Rocha Bruna A. Caetano Thais Mitsunari Luanda I. Santos Juliana M. Polatto Denise S. P. Q. Horton Beatriz E. C. Guth Luís Fernando dos Santos Roxane M. F. Piazza Shiga toxin (Stx)–producing Escherichia coli (STEC)...
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Arrays of manganese dioxide (MnO 2 ), a pseudocapacitive material, have been deposited on the carbon fibers (CF) of a carbon woven fabric by electrodeposition from a solution containing manganese sulfate and sulfuric acid using galvanostatic square waves. The thickness of the MnO 2 was varied by increasing/decreasing the time of deposition, and the electrochemical performance of the MnO 2 has been analyzed. The CF serves as a substrate material with high surface area, good electrical conductivity...
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In recent years, the development of electronic skin and smart wearable body sensors has put forward high requirements for flexible pressure sensors with high sensitivity and large linear measuring range. However, it turns out to be difficult to increase both of them simultaneously. In this paper, a flexible capacitive pressure sensor based on a porous carbon conductive paste-polydimethylsiloxane composite is reported, the sensitivity and the linear measuring range of which were developed...
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In this paper, we propose a one transistor-two resistive RAM (RRAM) (1T2R) device to overcome the non-ideal switching behavior of artificial synapse devices, such as the unidirectional and abrupt change in the conductance. Our findings reveal that the 1T2R device can exhibit bidirectional conductance changes using unidirectional switching RRAMs. Thus, we introduce a unidirectional but analog switching Cu-based RRAM device (Cu/Cu 2- X S/WO 3- X /W) having an internal voltage suppressor (Cu...
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Nanoscale artificially engineered spintronic materials could be used to enlarge the storage density of magnetic recording media. For this purpose, magnetic nanostructures such as antidot arrays exhibiting high uniaxial magnetic anisotropy are new contestants in the field of ultrahigh density magnetic data storage devices. In this context, we focus on the synthesis of nanostructured magnetic materials consisting of Dy–Fe alloyed antidot thin films, deposited onto the surface of nanoporous ...
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Leishmaniasis is a group of diseases caused by a protozoa parasite from one of over 20 Leishmania species. Depending on the tissues infected, these diseases are classified as cutaneous, mucocutaneous and visceral leishmaniasis. For the treatment of leishmaniasis refractory to antimony-based drugs, pentamidine (PTM) is a molecule of great interest. However, PTM displays poor bioavailability through oral routes due to its two strongly basic amidine moieties, which restricts its administration...
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Graphene (Gr) has been demonstrated to protect metallic thin films against oxidation. Based on this idea, we propose a new method to fabricate microstructured magnetic domains using patterned single-layer Gr. In the first experiment, single-layer Gr was transferred onto a CoPd alloy film pregrown on a SiO 2 /Si(001) substrate. Subsequently, the single-layer Gr was patterned through electron beam lithography followed by oxygen plasma etching to expose selective micron-sized areas of CoPd....
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Optimizing of electrocatalytic hydrogen evolution reaction (HER) activity is still a gigantic challenge for improving catalysts in renewable energy field. In this research, large-scale neoteric three-dimensional (3D) hierarchical MoSe 2 hollow sphere arrays with like-Pacific Plate architecture were triumphantly prepared via a facile and reliable approach. The like-Pacific Plate architecture consists of many 3D MoSe 2 arrays plates with the dimensions of 10–35 μ m, which is assembled by plentiful...
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Zinc-based nanoparticles are promising materials for various applications, including in biomedicine. The aim of our study was to determine the effect of fluorescent europium-doped zinc oxide nanoparticles (ZnO:Eu NPs) on sperm parameters, cell apoptosis and integrity of the blood–testis barrier (BTB) in mice. Nanostructures were orally administered to adult mice ( n = 34). Animals were sacrificed after 3 h, 24 h, 7 d and 14 d following oral administration. Sperm was collected and analysed...
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The synthesis of LiNbO 3 -type R3C ZnSnO 3 is still a challenging task under an extremely high-pressure condition. In this work, we have not only successfully synthesized R3C ZnSnO 3 nanowires (NWs) through a hydrothermal process, but ZnSnO 3 NWs with a high concentration of oxygen vacancies (referred to as ##IMG## [http://ej.iop.org/images/0957-4484/30/45/455401/nanoab35f9ieqn1.gif] {${{{\rm{ZnSnO}}}_{3}}^{{\rm{V}}}$} NWs), exhibiting a highly efficient hydrogen evolution reaction compared...
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There are remarkable studies geared towards developing mechanical analysis of nanoporous structures, while the size effect has been a major concern so far to improve strength or deformability. In this study, molecular dynamics simulations are utilized to study the pore shape effect on the mechanical behaviour of nanoporous silicon with circular, elliptical, square and hexagonal pore shapes. The influence of pore configuration on load transfer capabilities is studied for nanoporous silicon....
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Influence of barrier material and structure on carrier quantum confinement in GaAsBi quantum wells (QWs) is studied comprehensively. Single- and multi-QW structures were grown using solid-state molecular beam epitaxy with conventional rectangular, step-like and parabolically graded AlGaAs barrier designs. It was discovered that room temperature photoluminescence is increased by more than 50 times in the GaAsBi QWs with parabolically graded barriers (PGBs) if compared to standard rectangular...
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Abstract The core of solid tumors is characterized by hypoxia and a nutrient-starved microenvironment and has gained much attention as targets of anti-cancer drugs. In the course of search for selective growth inhibitors against the cancer cells adapted to nutrient starvation, epidithiodiketopiperazine DC1149B (1) together with structurally related compounds, trichodermamide A (2) and aspergillazine A (3), were isolated from culture extract of marine-derived Trichoderma lixii....
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11674-zGenetics implicate microglia in Alzheimer’s disease pathogenesis, but their roles remain unclear. Here, the authors find that microglial depletion in a mouse model of Alzheimer’s disease impairs plaque formation and that Aβ-induced changes in neuronal gene expression are microglia-mediated.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11738-0Each cell type in the tumour microenvironment has unique metabolic demands enabling specific functions. Here the authors use published single-cell RNA-seq data and develop a computational framework to better understand the heterogeneity of tumour metabolism, highlighting the discordance between results obtained from single cells and bulk tumours.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11742-4Hybrid superconductor-semiconductor devices offer a promising platform for topological superconductivity. Here, Ke and Moehle et al. create ballistic Josephson junctions in InSb quantum wells and use magnetic and electric fields to control their free energy landscape.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11768-8In a previous work, the authors have demonstrated the formation of localized waves in nematic liquid crystals driven by an electric field. Here they demonstrate the realization of solitary waves of (3+2)D type which can be steered along longitudinal and transverse directions by the electric field.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11643-6Silver nanoparticles are known environmental contaminants, however it is unclear whether they arise in soils through natural processes, anthropogenic processes, or both. Here Huang and colleagues offer fresh insight into the natural formation of these contaminants by soil particulate organic matter exposed to solar irradiation.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11320-8The Src-homology 3 domain of phosphatidyl-inositol-3-kinase (PI3K-SH3) is a model system for studying amyloid fibril formation. Here the authors present the 3.4 Å cryo-EM structure of the PI3K-SH3 amyloid fibril, which allows them to rationalize the effects of mutations on the kinetics of fibril formation.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11761-1Ultracold molecules are suitable platforms for precision measurements due to their internal degrees of freedom. Here the authors derive a limit on the variation of the electron-to-proton mass ratio by using the spectroscopy of ultracold KRb molecules.
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Nature Communications, Published online: 21 August 2019; doi:10.1038/s41467-019-11521-1Understanding fast phenomena that happen in hot and opaque environments, such as during metal foaming, remains a challenge. Here, the authors use ultra-fast imaging of more than 200 three-dimensional volumes per second to explore bubble coalescence in an aluminium alloy.
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Nature Reviews Clinical Oncology, Published online: 21 August 2019; doi:10.1038/s41571-019-0269-2Personalized MRD assays and therapy?
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Nature Reviews Drug Discovery, Published online: 21 August 2019; doi:10.1038/d41573-019-00146-0CD24 — a novel ‘don’t eat me’ signal
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Nature Reviews Immunology, Published online: 21 August 2019; doi:10.1038/s41577-019-0217-5The angiogenic growth factor placental growth factor is produced by TH17 cells and induces TH17 cell differentiation, which suggests a positive feedback loop between angiogenesis and autoimmunity in chronically inflamed tissues.
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Greater intake of long-chain omega-3 fatty acids doesn't seem to affect diabetes risk, according to a meta-analysis in The BMJ. Researchers analyzed...
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Rivaroxaban monotherapy is the most effective strategy for preventing deep-venous thrombosis (DVT) after elective total knee replacement, a meta-analysis in the Lancet Haematology...
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The health ministry of Spain on Wednesday issued an international alert after a listeriosis outbreak reached 150 cases, including one death, Reuters reports. An additional...
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Consider a situation where applicants 'A' and 'B' were equally liked by resident interviewers and were similarly involved in extracurriculars. The fair thing to do...
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Take a look at the latest from NEJM Group: NEJM Audio Interview: Climate Change and Health: Dr. Renee Salas discusses the effects of climate change...
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Publication date: October 2019Source: Neoplasia, Volume 21, Issue 10Author(s): Lydia B., Yina Z., Nina K., Andrea S., Sophie Luise B., Peter J., Florian G., Roland R., Antje M.AbstractWe recently described a positive feedback loop connecting c-MYC, NAMPT, DBC1 and SIRT1 that contributes to unrestricted cancer cell proliferation. Here we determine the relevance of the loop for serrated route intestinal tumorigenesis using genetically well-defined BrafV600E and K-rasG12D mouse models. In both models...
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AbstractBackgroundThe dearth of relevant tumor models reflecting the heterogeneity of human central nervous system metastasis (CM) has hindered development of novel therapies.MethodsWe established 39 CM patient-derived xenograft (PDX) models representing the histological spectrum, and performed phenotypic and multi-omic characterization of PDXs and their original patient tumors. PDX clonal evolution was also reconstructed using allele-specific copy number and somatic variants.ResultsPDXs retained...
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Publication date: Available online 21 August 2019Source: NeuroImageAuthor(s): Dimitris A. Pinotsis, Markus Siegel, Earl K. MillerAbstractMany recent advances in artificial intelligence (AI) are rooted in visual neuroscience. However, ideas from more complicated paradigms like decision-making are less used. Although automated decision-making systems are ubiquitous (driverless cars, pilot support systems, medical diagnosis algorithms etc.), achieving human-level performance in decision making tasks...
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Rapid sensory gain with emotional distracters precedes attentional deployment from a foreground task
Publication date: Available online 20 August 2019Source: NeuroImageAuthor(s): Valeria Bekhtereva, Matt Craddock, Christopher Gundlach, Matthias M. MüllerAbstractThe steady-state visual evoked potential (SSVEP), an electrophysiological marker of attentional resource allocation, has recently been demonstrated to serve as a neural signature of emotional content extraction from a rapid serial visual presentation (RSVP). SSVEP amplitude was reduced for streams of emotional relative to neutral scenes passively...
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Publication date: Available online 20 August 2019Source: Brain StimulationAuthor(s): B. Mostacci, F. Bisulli, L. Muccioli, I. Minardi, M. Bandini, L. Licchetta, M. Zucchelli, C. Leta, R. Michelucci, M. Zanello, P. Tinuper
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NEJM Interview: Dr. Renee Salas on the effects of climate change on human health and health systems.
Dr. Renee Salas is an affiliated faculty member at the Harvard Global Health Institute and an emergency medicine physician at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. R.N. Salas and C.G. Solomon. The Climate Crisis — Health and Care Delivery. N Engl J Med 2019;381:e13. C. Sorensen and R. Garcia-Trabanino. A New Era of Climate Medicine — Addressing Heat-Triggered Renal Disease. N Engl J Med 2019;381:693-696. G. McCarthy and...
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