Related ArticlesRhinotillexomania Manifesting as Empty Nose Syndrome. Ann Otol Rhinol Laryngol. 2019 Aug 16;:3489419870832 Authors: Tranchito E, Chhabra N Abstract OBJECTIVES: To highlight a severe case of rhinotillexomania (compulsive nasal picking) and its potential to manifest as empty nose syndrome (ENS). METHODS: A single case report with the presentation and management of a patient with severe rhinotillexomania who presented with chronic...
Related ArticlesAffordable Rapid Olfaction Measurement Array: A Novel, Essential Oil-Based Test Strongly Correlated with UPSIT and Subjective Outcome Measures. Ann Otol Rhinol Laryngol. 2019 Aug 16;:3489419870833 Authors: Villwock JA, Li J, Moore C, Chiu AG, Sykes KJ Abstract BACKGROUND: Olfactory dysfunction is an important facet of numerous disease states ranging from sinonasal disease to neurocognitive disorders. Due to expense and/or logistical barriers,...
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Related ArticlesThe C-Reactive Protein/Albumin Ratio as a Predictor of Mortality in Patients with HBV-Related Decompensated Cirrhosis. Clin Lab. 2019 Aug 01;65(8): Authors: Wang CJ, Wu JP, Zhou WQ, Mao WL, Huang HB Abstract BACKGROUND: The C-reactive protein to albumin ratio (CAR) is a novel inflammation index that has recently been used as a marker for poor prognosis or mortality in various patient groups. This study aimed to evaluate the association...
Related ArticlesClinical Prognostic Significance of HOXC9 Expression in Patients with Colorectal Cancer. Clin Lab. 2019 Aug 01;65(8): Authors: Hu M, Ou-Yang W, Jing D, Chen R Abstract BACKGROUND: Colorectal cancer (CRC) involves the abnormal expression of a set of genetic and epigenetic genes, which may be useful for predicting prognosis. The transcription factor homeobox C9 (HOXC9) is a member of the homeobox family and participates in diverse cellular...
Related ArticlesFast Interpretation of Thromboelastometry and Aggregometry in Patients Suffering from Chronic Liver Disease. Clin Lab. 2019 Aug 01;65(8): Authors: Stegewerth K, Weber CF, Moehlmann M, Adam EH, Zacharowski K, Zeuzem S, Weiler N Abstract BACKGROUND: Collective specific variegated alterations in the hemostatic system cast doubt on the uncritical usage of standard hemotherapy algorithms in patients with chronic liver disease. The aims of...
Related ArticlesExpression Level of Circulating Cell Free miR-155 Gene in Serum of Patients with Diabetic Nephropathy. Clin Lab. 2019 Aug 01;65(8): Authors: Akhbari M, Khalili M, Shahrabi-Farahani M, Biglari A, Bandarian F Abstract BACKGROUND: Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Several factors are known to contribute to the development and progression of diabetic nephropathy. Different microRNAs have...
Related ArticlesThe Use of TEG Technology as a Prediagnostic Tool. Clin Lab. 2019 Aug 01;65(8): Authors: Sarkar MK PMID: 31414763 [PubMed - in process]
Related ArticlesPrevalence of Hyperuricemia and its Correlation with Serum Lipids and Blood Glucose in Physical Examination Population in 2015 - 2018: a Retrospective Study. Clin Lab. 2019 Aug 01;65(8): Authors: Yang WX, Ma Y, Hou YL, Wang YB, You CG Abstract BACKGROUND: Hyperuricemia (HUA) is a metabolic disease caused by a disorder of purine metabolism, which increases the risk of cardio-cerebrovascular disease. Serum lipids and blood glucose are risk...
Related ArticlesPersistent Isolated Elevation of Aspartate Aminotransferase in an Asymptomatic Female Patient: a Case Report and Review of Current Literature. Clin Lab. 2019 Aug 01;65(8): Authors: Mrosewski I, Bredlau B, Öztürk Y, Switkowski R Abstract BACKGROUND: Persistent isolated elevation of aspartate aminotransferase (AST) is a rare observation and might lead to unnecessary laboratory testing and invasive procedures, if the possibility of macro-AST...
Related ArticlesCirculating lncRNA ANRIL in the Serum of Patients with Ischemic Stroke. Clin Lab. 2019 Aug 01;65(8): Authors: Zhang K, Qi M, Yang Y, Xu P, Zhua Y, Zhang J Abstract BACKGROUND: The current study aims to investigate the expression of antisense noncoding RNA in the INK4 locus (ANRIL) in serum of patients with ischemic stroke and its correlation with high-sensitivity C-reactive protein (hs-CRP) and matrix metalloproteinase-9 (MMP-9). ...
Related ArticlesClinical Diagnosis Value of miR-29b-3p in Peripheral Blood Mononuclear Cells and Synovial Fluid Among Osteoarthritis Patients. Clin Lab. 2019 Aug 01;65(8): Authors: Chen C, Chen H Abstract BACKGROUND: The current study aims to verify the abnormal expression of miR-29b-3p in peripheral blood mono-nuclear cells and synovial fluid of patients with osteoarthritis (OA), and to explore whether this abnormality is related to the severity of...
Related ArticlesComparison of the Xpert CARBA-R Test and Phenotypical Tests for Detection of Carbapenemases Types in Multidrug Resistant K. pneumoniae Isolates. Clin Lab. 2019 Aug 01;65(8): Authors: Terzi HA, Aydemir O, Kilic U, Demiray T, Koroglu M, Altindis M, Erkorkmaz U Abstract BACKGROUND: The objective of this study is to evaluate the performance of the Xpert CARBA-R Test and the phenotyping confirmation tests (MHT, CIM, Mastdiscs, and Carba NP)...
Related ArticlesLeft Lung Neoplasms and Bilateral Pleural Effusion Combined Elevated Carcinoembryonic Antigen in Pleural Effusion with Negative Result of Thoracoscopy Pleural Biopsy Misdiagnosed as Lung Carcinoma Ultimately Confirmed Pulmonary Sarcomatoid Carcinoma by CT-guided Percutaneous Lung Biopsy: a Case Report and Literature Review. Clin Lab. 2019 Aug 01;65(8): Authors: Zhang Q, Wang MH, Li WQ, Wang HY, Rana MA, Chen Y, Liu CH, Zhang S, Jin YX, Zhang C, Zhu XY,...
Related ArticlesHigh Urinary Kidney Injury Molecule-1 and Neutrophil Gelatinase-Associated Lipocalin are Associated with Increased Risk of Chronic Kidney Disease in Patients with Type 2 Diabetes. Clin Lab. 2019 Aug 01;65(8): Authors: Stein CS, Carvalho JAM, Duarte MMMF, Comim FV, Premaor MO, Moretto MB, Moresco RN PMID: 31414756 [PubMed - in process]
Related ArticlesEvaluation of the Interference of Lipemia and Hemolysis in the Detection Limit of Anti-HIV-1 Antibodies. Clin Lab. 2019 Aug 01;65(8): Authors: Mendoza-Benitez PS, Aguilar-Ruiz SR, Romero-Tlalolini MD, Torres-Aguilar H Abstract BACKGROUND: The instructions of manufacturers of methodologies for anti-HIV-1/2 antibodies screening tests re-commend avoiding analyzing blood samples with hemolysis or lipemia, but they do not mention references...
Related ArticlesIncreased Expression of miR-494 in Serum of Patients with Prostate Cancer and its Potential Diagnostic Value. Clin Lab. 2019 Aug 01;65(8): Authors: Cai B, Peng JH Abstract BACKGROUND: Prostate cancer is a common male cancer with poor prognosis, and to find molecular diagnostic markers for the early diagnosis of prostate cancer is urgently needed. The aim of this study is to investigate the diagnostic value of serum expression level of...
Related ArticlesRight Lung Consolidation Combined Elevated Serum Neuron Specific Enolase Misdiagnosed as Lung Carcinoma Ultimately Confirmed Pulmonary Cryptococcosis by CT-guided Percutaneous Lung Biopsy: a Case Report and Literature Review. Clin Lab. 2019 Aug 01;65(8): Authors: Zhang Q, Li WQ, Wang MH, Wang HY, Chen Y, Liu CH, Zhang S, Zhang C, Zhu XY, Fu AS, Ge YL Abstract BACKGROUND: Detection of serum neuron specific enolase (NSE) has high sensitivity...
Related ArticlesStorage and Transportation of "HIV" RNA in Plasma Samples up to 45°C in a Lyophilized Stabilizer. Clin Lab. 2019 Aug 01;65(8): Authors: Weidner J, Hünger F, Odaibo G, Olaleye D, Reichelt D, Greve B, Cassens U Abstract BACKGROUND: Blood or plasma samples from rural areas are often transported under suboptimal conditions to central laboratories. The negative influence of different storage temperatures during transportation as well as long...
Related ArticlesHematological Indices of Pregnant Women at the University of Gondar Referral Hospital, Northwest Ethiopia: a Comparative Cross-Sectional Study. Clin Lab. 2019 Aug 01;65(8): Authors: Alemu A, Abebe M, Terefe B, Yesuf M, Melku M, Enawgaw B, Biadgo B Abstract BACKGROUND: Pregnancy is a natural physiological variation as a result of hormonal and metabolic changes. Worldwide a large proportion of women are expected to die each year as a result...
Related ArticlesDiagnostic Values of Neutrophil and Neutrophil to Lymphocyte Ratio in Distinguishing between Acute Cerebral Infarction and Vertigo. Clin Lab. 2019 Aug 01;65(8): Authors: Zhang Y, Jiang L, Yang P, Zhang Y Abstract BACKGROUND: Vertigo and acute cerebral infarction (ACI) patients show similar symptoms such as dizziness and imbalance. This study was to investigate the diagnostic values of neutrophil counts and neutrophil to lymphocyte ratio...
Related ArticlesMolecular Detection of blaIMP Genes in Metallo-Beta-Lactamase Producing Clinical Gram-Negative Isolates. Clin Lab. 2019 Aug 01;65(8): Authors: Abbas S, Ejaz H, Jahan S, Younas S, Alzahrani B, Farraj DAA, Alkufeidy RM Abstract BACKGROUND: The use of carbapenem antibiotics in the treatment of serious Gram-negative bacterial infections is under threat due to the emergence of the blaIMP gene amongst the bacterial pathogens. METHODS:...
Related ArticlesPotential Diagnostic Value of Plasma Long-Chain Non-Coding RNA HIT in Breast Cancer. Clin Lab. 2019 Aug 01;65(8): Authors: Hou H, Li F, Yang W, Wang H Abstract BACKGROUND: The current study aims to investigate the expression of HOXA transcript induced by transforming growth factor-β (TGF-β) (HIT) in plasma of women with breast cancer and its potential diagnostic value for breast cancer. METHODS: qRT-PCR was used to detect the...
Related ArticlesEvaluation of MARK BTM for Quantitative Measurement of Three Tumor Markers: Prostate Specific Antigen, Alpha Fetoprotein, and Carcinoembryonic Antigen. Clin Lab. 2019 Aug 01;65(8): Authors: Hwang H, Kim J, Choi J, Kim KH, Han HS Abstract BACKGROUND: Tumor marker assays have played a crucial role for screening cancers and monitoring cancer patients, as they reflect the status and prognosis of patients. Alpha fetoprotein (AFP), prostate...
Related ArticlesIncreased Serum Sedimentation and Positive Tuberculosis Antibody Combined Left Lung Consolidation in Chest CT Scan in an Adult Patient Firstly Misdiagnosed as Tuberculosis Proved as Foreign Body Aspiration in the Left Main Stem Bronchus by Bronchoscopy: a Case Report and Literature Review. Clin Lab. 2019 Aug 01;65(8): Authors: Ge YL, Chen Y, Wang MH, Zhang Q, Li WQ, Liu CH, Zhang HF, Zhang S, Hao C, Zhang C, Zhu XY, Li LQ, Fu AS Abstract ...
Related ArticlesDistribution of HCV Genotypes in Tianjin, China and Characterization of a Full-Length Viral Genome Representing Subtype 6xa. Clin Lab. 2019 Aug 01;65(8): Authors: Hou W PMID: 31414745 [PubMed - in process]
Related ArticlesPlasma Long Non-Coding RNA Expression Profiles in Patients with Rheumatoid Arthritis. Clin Lab. 2019 Aug 01;65(8): Authors: Qin W, Wang TH, Xie BH, Sun QQ, Huang H, Zhao BJ, Cen H, Wu XD Abstract BACKGROUND: Recently, long non-coding RNAs (lncRNAs) have attracted substantial attention owing to their unforeseen critical roles in a wide range of biological processes. The aim of our study was to provide an overview of lncRNA expression profiles...
Related ArticlesNegative (1,3)-β-D-glucan and Elevated White Blood Cells Combined Procalcitonin Masquerading as Severe Pneumonia Eventually Diagnosed as Invasive Pulmonary Aspergillosis Proven by Bronchoalveolar Lavage Fluid Culture in a Diabetes Patient: a Case Report and Literature Review. Clin Lab. 2019 Aug 01;65(8): Authors: Ge YL, Zhang Q, Wang MH, Li LQ, Fu AS, Liu CH, Zhang HF, Li WQ, Chen Y, Zhang S, Hao C, Zhang C, Zhu XY Abstract BACKGROUND:...
Related ArticlesEstablishment of Reference Intervals for Serum Cytokeratin-19 Fragment and Neuron Specific Enolase by Indirect Method Using Data Obtained from Healthy Chinese Population in Chengdu. Clin Lab. 2019 Aug 01;65(8): Authors: Zhen SH, Wang Y, Gu CG, Liu D, Shen XX Abstract BACKGROUND: In order to establish suitable reference intervals (RIs) of serum cytokeratin-19 fragment (Cyfra211) and neuron specific enolase (NSE) for the healthy Chinese...
Related ArticlesMolecular Approach for HIV-1 Replication Inhibition: Assessment of Different siRNAs Targeting Tat and Nef Genes to Effectively Suppress their Expression. Clin Lab. 2019 Aug 01;65(8): Authors: Rahimi P, Aghasadeghi MR, Arefian E, Mobarakeh VI, Kamalzare S, SajadianFard FS, Amiran MR Abstract BACKGROUND: Inhibition of viral genes through siRNA seems to be promising for treatment of complicated viral infections like human immunodeficiency...
Related ArticlesPerformance Evaluation of IGRA-ELISA and T-SPOT.TB for Diagnosing Tuberculosis Infection. Clin Lab. 2019 Aug 01;65(8): Authors: Zhu M, Zhu Z, Yang J, Hu K Abstract BACKGROUND: To explore the application value of IGRA-ELISA in the diagnosis of tuberculosis. METHODS: A total of 68 tuberculosis and 58 other pulmonary disease case samples were obtained. All the samples were tested by IGRA-ELISA and T-SPOT.TB assay in parallel. The...
Related ArticlesParacoccus yeei: a Rare Opportunistic Bacterium in a Patient with Parotid Cyst. Clin Lab. 2019 Aug 01;65(8): Authors: He S, Li Z, Quan M, Hong Z, Yang Q Abstract BACKGROUND: Parotid cyst is a common problem in patients treated by surgeons. However, Paracoccus yeei was isolated from an aerobic blood culture in a patient with parotid cyst as an unusual etiologic opportunistic agent. METHODS: Since old biochemical identification...
Related ArticlesDiscrepancy in Chloride Measurement with Decreasing Bicarbonate Concentrations. Clin Lab. 2019 Aug 01;65(8): Authors: Bihari S, Galluccio S Abstract BACKGROUND: Accurate chloride measurement is important in critically ill patients. METHODS: Chloride concentration measured simultaneously between the central laboratory (indirect ion-selective electrode) and blood gas analysis (direct ion-selective electrode) were compared. ...
Related ArticlesPositive Relationship of Platelet Volume Indices with HbA1c in Unselected Type-2 Diabetes Mellitus Patients. Clin Lab. 2019 Aug 01;65(8): Authors: Wu M, Xiao L, Yang X Abstract BACKGROUND: The aim of this study is to investigate the relationship of several platelet volume indices with glycated hemoglobin (HbA1c) in a large cohort of type 2 diabetes mellitus (T2DM) patients. METHODS: This is a retrospective study conducted on...
Related ArticlesThe Clinical and Laboratory Impact of Upgrading Clostridioides (formerly Clostridium) difficile Infection Testing from Routine to Molecular Based-Algorithm: an Observational Case-Study from the Eastern Province, Saudi Arabia. Clin Lab. 2019 Aug 01;65(8): Authors: Alnimr A, Alwazzeh MJ, Al-Ameer A Abstract BACKGROUND: Clostridioides (formerly Clostridium) difficile infection (CDI) is linked to misuse of antimicrobials. The prevalence of...
Related ArticlesSignificance of Serological Gastric Biopsy in Different Gastric Mucosal Lesions: an Observational Study. Clin Lab. 2019 Dec 01;65(12): Authors: Dong Z, Zhang X, Chen X, Zhang J Abstract BACKGROUND: Screening and timely treatment of precancerous gastric cancer diseases or of gastric cancer in the early stages has important significance in reducing the incidence and mortality of gastric cancer. Gastroscopy and histopathological biopsy are...
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Related ArticlesLiquid biopsy of cerebrospinal fluid identifies neuronal pentraxin receptor (NPTXR) as a biomarker of progression of Alzheimer's disease. Clin Chem Lab Med. 2019 Aug 15;: Authors: Lim B, Tsolaki M, Soosaipillai A, Brown M, Zilakaki M, Tagaraki F, Fotiou D, Koutsouraki E, Grosi E, Prassas I, Diamandis EP Abstract Background Alzheimer's disease (AD) is the most prevalent form of dementia. Currently, the most studied biomarkers of AD are...
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Related ArticlesCorrection: PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix. Oncotarget. 2019 Jul 30;10(46):4802 Authors: Mann M, Kumar S, Chauhan SS, Bhatla N, Kumar S, Bakhshi S, Gupta R, Sharma A, Kumar L Abstract [This corrects the article DOI: 10.18632/oncotarget.27008.].PMID: 31413820 [PubMed - in process]
Related ArticlesGenomics applied to the treatment of breast cancer. Oncotarget. 2019 Jul 30;10(46):4786-4801 Authors: Hamdan D, Nguyen TT, Leboeuf C, Meles S, Janin A, Bousquet G Abstract Breast cancer remains a major health issue in the world with 1.7 million new cases in 2012 worldwide. It is the second cause of death from cancer in western countries. Genomics have started to modify the treatment of breast cancer, and the developments should become...
Related ArticlesCartilage oligomeric matrix protein in patients with osteoarthritis is independently associated with metastatic disease in prostate cancer. Oncotarget. 2019 Jul 30;10(46):4776-4785 Authors: Rosas S, Hughes RT, Farris M, Lee H, McTyre ER, Plate JF, Shi L, Emory CL, Blackstock AW, Kerr BA, Willey JS Abstract Metastatic prostate cancer has a 5-year survival rate of 30%. Identifying predictors of metastasis outcome could potentially reduce...
Related ArticlesPrecision delivery of RAS-inhibiting siRNA to KRAS driven cancer via peptide-based nanoparticles. Oncotarget. 2019 Jul 30;10(46):4761-4775 Authors: Strand MS, Krasnick BA, Pan H, Zhang X, Bi Y, Brooks C, Wetzel C, Sankpal N, Fleming T, Goedegebuure SP, DeNardo DG, Gillanders WE, Hawkins WG, Wickline SA, Fields RC Abstract Over 95% of pancreatic adenocarcinomas (PDACs), as well as a large fraction of other tumor types, such as colorectal...
Related ArticlesKDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells. Oncotarget. 2019 Jul 30;10(46):4743-4760 Authors: Okamoto K, Tanaka Y, Ogasawara S, Obuse C, Nakayama JI, Yano H, Tsuneoka M Abstract Triple-negative breast cancer (TNBC) is very aggressive and lacks specific therapeutic targets. Ribosome RNAs (rRNAs) are central components of ribosomes and transcribed...
Related ArticlesTumor-associated macrophages and individual chemo-susceptibility are influenced by iron chelation in human slice cultures of gastric cancer. Oncotarget. 2019 Jul 30;10(46):4731-4742 Authors: Prill S, Rebstock J, Tennemann A, Körfer J, Sönnichsen R, Thieme R, Gockel I, Lyros O, Monecke A, Wittekind C, Weimann A, Grosser K, Wiechmann V, Kubick C, Bechmann I, Lordick F, Kallendrusch S Abstract Purpose: Presence of tumor-associated macrophages...
Related ArticlesSomatostatin receptor 2 targeting in small cell lung carcinoma: perspectives. Oncotarget. 2019 Jul 30;10(46):4727-4730 Authors: Lehman JM, aMassion PP Abstract Small Cell lung carcinoma (SCLC) is the most lethal and aggressive subtype of lung cancer. Novel targeting approaches and agents are desperately needed. In this perspectives, we briefly explore recent data published in the International Journal of Cancer suggesting Somatostatin...
Related ArticlesEGFR and mTOR as therapeutic targets in glioblastoma. Oncotarget. 2019 Jul 30;10(46):4721-4723 Authors: Ronellenfitsch MW, Luger AL, Steinbach JP PMID: 31413813 [PubMed]
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Related ArticlesTargeted delivery of doxorubicin to HER2 positive tumor models. Int J Nanomedicine. 2019;14:5679-5690 Authors: Gomari H, Forouzandeh Moghadam M, Soleimani M, Ghavami M, Khodashenas S Abstract Background: Exosomes are natural nanovesicles with unique characteristics, such as long circulating half-life, the intrinsic ability to target tissues, biocompatibility, and minimal or no inherent systemic toxicity. Mesenchymal stem cells produce...
Related ArticlesA novel asymmetrical anti-HER2/CD3 bispecific antibody exhibits potent cytotoxicity for HER2-positive tumor cells. J Exp Clin Cancer Res. 2019 Aug 14;38(1):355 Authors: Yu S, Zhang J, Yan Y, Yao X, Fang L, Xiong H, Liu Y, Chu Q, Zhou P, Wu K Abstract BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is overexpressed in multiple cancers, which is associated with poor prognosis. Herceptin and other agents targeting HER2 have potent...
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Related ArticlesVEMPs and Dysautonomia Assessment in Definite Cerebellar Ataxia, Neuropathy, Vestibular Areflexia Syndrome (CANVAS): a Case Series Study. Cerebellum. 2019 Aug 15;: Authors: Moreno-Ajona D, Álvarez-Gómez L, Manrique-Huarte R, Rivas E, Martínez-Vila E, Pérez-Fernández N Abstract Cerebellar ataxia with neuropathy and vestibular areflexia syndrome (CANVAS) is a recently described slowly progressive ataxia with severe imbalance due to the...
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Related ArticlesComparing the effects of Portulaca oleracea seed hydro-alcoholic extract, valsartan, and vitamin E on hemodynamic changes, oxidative stress parameters and cardiac hypertrophy in thyrotoxic rats. Drug Chem Toxicol. 2019 Aug 15;:1-8 Authors: Pakdel R, Vatanchian M, Niazmand S, Beheshti F, Rahimi M, Aghaee A, Hadjzadeh MA Abstract The present study compared the effects of Portulaca oleracea (P. oleracea) seed hydro-alcoholic extract, valsartan,...
Related ArticlesCardioprotective effects of hesperidin on carbon monoxide poisoned in rats. Drug Chem Toxicol. 2019 Aug 14;:1-6 Authors: Rezaee R, Sheidary A, Jangjoo S, Ekhtiary S, Bagheri S, Kohkan Z, Dadres M, Oana Docea A, Tsarouhas K, Sarigiannis DA, Karakitsios S, Tsatsakis A, Kovatsi L, Hashemzaei M Abstract Carbon monoxide (CO) poisoning causes cardiotoxicity and so far, no definite antidote has been proposed to overcome CO-induced adverse outcomes....
Related ArticlesToxicological evaluation of ergocalciferol, cholecalciferol, and their metabolites by a category approach. Drug Chem Toxicol. 2019 Aug 14;:1-7 Authors: Tugcu G, Charehsaz M, Aydın A Abstract Predictive toxicology plays an integral role in determining the toxicological profiles of chemicals for safety assessment. Vitamin D is an essential vitamin for the regulation of calcium absorption and homeostasis, as well as the treatment and prevention...
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Related ArticlesComparison of Outcomes of Fasciocutaneous Free Flaps and Jejunal Free Flaps in Pharyngolaryngoesophageal Reconstruction: A Systematic Review and Meta-Analysis: Erratum. Ann Plast Surg. 2019 Sep;83(3):369 Authors: PMID: 31415294 [PubMed - in process]
Related ArticlesOne-Piece Fronto-orbital Distraction With Midline Splitting But Without Bandeau for Metopic Craniosynostosis: Craniometric, Volumetric, and Morphologic Evaluation. Ann Plast Surg. 2019 Sep;83(3):285-292 Authors: Fawzy HH, Choi JW, Ra YS Abstract BACKGROUND: Distraction osteogenesis has gained popularity in the treatment of different types of craniosynostosis. We aimed to present the technique of 1-piece fronto-orbital distraction with...
Related ArticlesScope of Hand Surgery Using Surgeon Administered Local/Regional Anaesthesia. Ann Plast Surg. 2019 Sep;83(3):278-284 Authors: Sim WP, Ng HJH, Tan S, Bajaj SL, Rajaratnam V Abstract INTRODUCTION: Hand and wrist surgeries are often carried out under local/regional anesthesia. We describe our experience using Surgeon Administered Local/Regional Anaesthesia (SALoRA) without sedation to deliver acute and elective hand surgery anesthesia in...
Related ArticlesAutologous Fat Grafting in Young Patients: A Simple and Effective Way to Achieve Facial Balance. Ann Plast Surg. 2019 Sep;83(3):253-257 Authors: Maia M, Lukash FN Abstract GOALS/PURPOSE: Rhinoplasty is the most common procedure seen in the teenage population. Many of these patients have facial imbalance both recognized and unrecognized by the individual and family. Most often it involves chin or midface deficiency. When the discussion...
Related ArticlesPatient-Reported Outcome Measures in Plastic Surgery: An Introduction and Review of Clinical Applications. Ann Plast Surg. 2019 Sep;83(3):247-252 Authors: Sharma K, Steele K, Birks M, Jones G, Miller G Abstract Clinical care is often directed at improving patient's quality of life, the effectiveness of which can be measured by objective or subjective outcomes. Surgical intervention, especially in plastic and reconstructive surgery, can...
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Related ArticlesAvoiding blindness in managing epistaxis for a child with Duane's Retraction Syndrome. Int J Pediatr Otorhinolaryngol. 2019 Jul 29;126:109615 Authors: Ahmadi N, Huang J, North HJ, Lord D, Cheng AT Abstract Duane's Retraction Syndrome (DRS), a congenital cranial dysinnervation disorder, accounts for 5% of all strabismus. A vascular anomaly in DRS, which became clinically relevant in the context of significant epistaxis, is presented. A...
Related ArticlesReducing the number of impulses in video head impulse testing - It's the quality not the numbers. Int J Pediatr Otorhinolaryngol. 2019 Aug 09;125:206-211 Authors: Wenzel A, Hülse R, Thunsdorff C, Rotter N, Curthoys I Abstract OBJECTIVES: The video-Head-Impulse-Test (vHIT) is widely used to evaluate vestibular function. Nevertheless, there is no consensus on the necessary or ideal number of impulses performed for robust VOR gains. Therefore,...
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Related Articles[Upper Airway Stimulation for obstructive sleep apnea-Can radiological position monitoring predict tongue motion one year after implantation? German version]. HNO. 2019 Aug 14;: Authors: Steffen A, Wozny AS, König IR, Goltz JP, Wollenberg B, Hasselbacher K Abstract BACKGROUND: Tongue motion patterns (TMP) can influence the outcome of upper airway stimulation (UAS) in the treatment of obstructive sleep apnea (OSA). As a postoperative control...
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Related ArticlesChanging prescribing behaviours with educational outreach: an overview of evidence and practice. BMC Med Educ. 2019 Aug 14;19(1):311 Authors: Kunstler BE, Lennox A, Bragge P Abstract BACKGROUND: General practitioners (GPs), or family practitioners, are tasked with prescribing medications that can be harmful to the community if they are inappropriately prescribed or used (e.g. opioids). Educational programs, such as educational outreach...
Related ArticlesVideo feedback and e-Learning enhances laboratory skills and engagement in medical laboratory science students. BMC Med Educ. 2019 Aug 14;19(1):310 Authors: Donkin R, Askew E, Stevenson H Abstract BACKGROUND: Traditionally, the training of medical laboratory science students has taken place in the laboratory and has been led by academic and pathology experts in a face-to-face context. In recent years, budgetary pressures, increasing student...
Related ArticlesTrust in Group Decisions: a scoping review. BMC Med Educ. 2019 Aug 14;19(1):309 Authors: Sapp JE, Torre DM, Larsen KL, Holmboe ES, Durning SJ Abstract BACKGROUND: Trust is a critical component of competency committees given their high-stakes decisions. Research from outside of medicine on group trust has not focused on trust in group decisions, and "group trust" has not been clearly defined. The purpose was twofold: to examine the definition...
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Related ArticlesCan Digital Breast Tomosynthesis Solve the Challenge of Dense Breast Parenchyma? Radiology. 2019 Aug 13;:191589 Authors: Fuchsjäger MH, Adelsmayr G PMID: 31414962 [PubMed - as supplied by publisher]
Related ArticlesCan We Use MRI and US to Predict Axillary Node Response in Breast Cancer? Radiology. 2019 Aug 13;:191642 Authors: Whitman GJ PMID: 31414961 [PubMed - as supplied by publisher]
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Related ArticlesDo Ice Packs Reduce Postoperative Midline Incision Pain, NSAID or Narcotic Use? World J Surg. 2019 Aug 14;: Authors: Ravindhran B, Rajan S, Balachandran G, Mohan LN Abstract BACKGROUND: Adequate postoperative analgesia, especially after major abdominal surgery is important for recovery, early mobility, and patient satisfaction. We aimed to study the effects of cryotherapy via an ice pack in the immediate postoperative period, for patients...
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Related ArticlesUnderstanding reliever overuse in patients purchasing over-the-counter short-acting beta2 agonists: an Australian community pharmacy-based survey. BMJ Open. 2019 Aug 14;9(8):e028995 Authors: Azzi EA, Kritikos V, Peters MJ, Price DB, Srour P, Cvetkovski B, Bosnic-Anticevich S Abstract OBJECTIVES: Overuse of asthma relievers is associated with significant adverse consequences. This study aimed to better understand the population purchasing...
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Publication date: Available online 15 August 2019Source: Clinical Neurology and NeurosurgeryAuthor(s): Hui Li, Yuanliang Xie, Xiang Wang, Faxiang Chen, Jianqing Sun, Xiaoli JiangAbstractObjectiveTo explore the value of radiomics features on non-contrast computed tomography (NCCT) in predicting early enlargement of spontaneous intracerebral hemorrhage (SICH).Patients and Methods167 patients with SICH were divided into enlarged hematoma and non-enlarged hematoma groups based on the volume of hematoma...
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Background Anti-thymocyte globulin (ATG) as induction therapy in renal transplantation is facing the dilemma of reducing the incidence of acute rejection (AR) and delayed graft function (DGF) or increasing risks of infection and malignancy. The purpose of this study was to delineate the safety and efficiency of the optimal ATG dosage. Methods We retrospectively evaluated 91 deceased donor kidney transplant recipients (KTRs) in our institution between March 2011 and January 2019. The patients...
Plant defense against pathogens and abiotic stresses is regulated differentially by communicating signal transduction pathways in which nitric oxide (NO) plays a key role. Here, we show the biological role of Arabidopsis thaliana wall-associated kinase (AtWAK) Like10 (AtWAKL10) that exhibits greater than a 100-fold change in transcript accumulation in response to the NO donor S-nitroso-L-cysteine (CysNO), identified from high throughput RNA-seq based transcriptome analysis. Loss of AtWAKL10 function...
Barnacles and their allies (Thecostraca) are a biologically diverse, monophyletic crustacean group, which includes both intensely studied taxa, such as the acorn and stalked barnacles, as well as cryptic taxa, for example, Facetotecta. Recent efforts have clarified phylogenetic relationships in many different parts of the barnacle tree, but the outcomes of these phylogenetic studies have not yet been combined into a single hypothesis for all barnacles. In the present study, we applied a new “synthesis”...
Protein aggregation into amyloid fibrils has been linked to multiple neurodegenerative disorders. Determining the kinetics of fibril formation, as well as their structural stability are important for the mechanistic understanding of amyloid aggregation. Tracking both fibril association and dissociation is usually performed by measuring light scattering of the solution or fluorescence of amyloid specific dyes, such as thioflavin-T. A possible addition to these methods is the recently discovered deep-blue...
Current theories argue that hyper-sensitisation of social threat perception is central to paranoia. Affected people often also report misperceptions of group cohesion (conspiracy) but little is known about the cognitive mechanisms underpinning this conspiracy thinking in live interactions. In a pre-registered experimental study, we used a large-scale game theory approach (N > 1,000) to test whether the social cohesion of an opposing group affects paranoid attributions in a mixed online and lab-based...
Background Organ cross-talk describes interactions between a primary affected organ and a secondarily injured remote organ, particularly in lung-brain interactions. A common theory is the systemic distribution of inflammatory mediators that are released by the affected organ and transferred through the bloodstream. The present study characterises the baseline immunogenic effects of a novel experimental model of random allogeneic blood transfusion in pigs designed to analyse the role...
Background Bacterial symbiosis is widespread in arthropods, especially in insects. Some of the symbionts undergo a long-term co-evolution with the host, resulting in massive genome decay. One particular consequence of genome decay is thought to be the elimination of transcriptional elements within both the coding region and intergenic sequences. In the whitefly Bemisia tabaci species complex, the obligate symbiont Candidatus Portiera aleyrodidarum is of vital importance in nutrient...
Background Previous studies have indicated that variations in the vaginal microbiome result in symptomatic conditions. Group B Streptococcus (GBS) is a significant neonatal pathogen and maternal vaginal colonization has been recognized as an important risk factor for neonatal disease. Therefore, it is important to discover the relationship between the composition of the vaginal microbiome and GBS colonization. This study explores the potential relationship between the composition...
Gut microbiota have important functions in the body, and imbalances in the composition and diversity of those microbiota can cause several diseases. The host fosters favorable microbiota by releasing specific factors, such as microRNAs, and nonspecific factors, such as antimicrobial peptides, mucus and immunoglobulin A that encourage the growth of specific types of bacteria and inhibit the growth of others. Diet, antibiotics, and age can change gut microbiota, and many studies have shown the relationship...
Purpose This research aimed to identify risk factors of pulmonary metastasis (PM) from hepatocellular carcinoma (HCC) and prognostic factors of patients with PM from HCC at initial diagnosis. Methods Patients diagnosed with HCC between 2010 and 2015 were reviewed retrospectively in the Surveillance, Epidemiology, and End Results (SEER) database. Patients with PM from HCC at initial diagnosis were identified from the entire cohort. Predictors for PM from HCC were identified by multivariate...
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Abstract Purpose Reorganization of the brain is considered the key mechanism of functional recovery in patients after spinal cord injury (SCI). This meta-analysis assessed abnormal brain activation in SCI patients to understand the pattern of reorganization in the brain after SCI. Methods Functional magnetic resonance imaging (fMRI) studies that compared...
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Abstract Background Calcifications along ventricular catheters have been associated with shunt fractures although it is unknown whether their development predicts whether and when the shunts will fracture. Objective To determine whether extracranial calcifications found on a radiographic shunt series predicts whether a patient will experience a shunt catheter...
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