In the ovule evolution, the integument is the most attention point in discussion as a morphologic character of the seed plants. There are several theories and hypotheses about the origin of the integument were presented in the history. However, the development and function of the ovule envelopes are not so clear until now. The development of thehe basal gymnosperms Cycas and Zamia were to investigated, especially of the integument to complement the existing knowledge in seed plants. The development...
Pheromones are important for courtship and mate choice in many insects, but we know relatively little of their role in butterflies. The butterfly Heliconius melpomene uses a complex blend of wing androconial compounds during courtship. Electroantennography in H. melpomene and its close relative H. cydno showed that responses to androconial extracts were not species-specific. Females of both species responded more strongly to the H. cydno extract, suggesting conservation of peripheral nervous system...
Pheromones are important for courtship and mate choice in many insects, but we know relatively little of their role in butterflies. The butterfly Heliconius melpomene uses a complex blend of wing androconial compounds during courtship. Electroantennography in H. melpomene and its close relative H. cydno showed that responses to androconial extracts were not species-specific. Females of both species responded more strongly to the H. cydno extract, suggesting conservation of peripheral nervous system...
Evolutionary rescue is the process by which a declining population successfully adapts genetically to avoid extinction. In a subdivided population composed of different patches that one after the other deteriorate, dispersal can significantly alter the chances of evolutionary rescue of a wild type population not viable in deteriorated patches. Here, we investigate the effect of different dispersal schemes and intensities on the probability of successful establishment of a mutant population, adapted...
Species are subjected to variable environment in nature. While the ability to cope with changes has been studied through theoretical approaches, the small number of empirical studies limits our understanding of the evolutionary molecular mechanisms underlying adaptation to fluctuations. Whole transcriptome sequencing of the fungal wheat pathogen Zymoseptria tritici revealed the evolution of gene expression after 48 weeks of experimental evolution under stable or fluctuating temperature. We found...
Polyploidy has played an important role in evolution across the tree of life but it is still unclear how polyploid lineages may persist after their initial formation. While both common and well-studied in plants, polyploidy is rare in animals and generally less well- understood. The Australian burrowing frog genus Neobatrachus is comprised of six diploid and three polyploid species and offers a powerful animal polyploid model system. We generated exome-capture sequence data from 87 individuals representing...
Individuals differ in their life courses, but how this diversity is generated, how it has evolved and how maintained is less understood. However, this understanding is crucial to comprehend evolutionary and ecological population dynamics. In structured populations, individual life courses represent sequences of stages that end in death. These sequences can be described by a Markov chain and individuals diversify over the course of their lives by transitioning through diverse discrete stages. The...
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An instrument to measure perceptions of people with disabilities regarding the application of international...An instrument to measure perceptions of people with disabilities regarding the application of international vocational rehabilitation standardsThis study aimed to create a valid and reliable instrument to measure people with disabilities' perceptions regarding the extent of application of international standards issued by the Council of Europe, International Labour Organization, and the International...
https://www.youtube.com/watch?v=DFOhpBjLqN4&t=1s,Η ΘΕΡΑΠΕΙΑ ΓΙΑ ΟΛΕΣ ΤΙΣ ΑΣΘΕΝΕΙΕΣ 1 Περιεχόμενα Σύντομο βιογραφικό Πρόλογος μεταφραστή Η θεραπεία όλων των ασθενειών Σημείωση του συγγραφέα Πρόλογος Η υπόσχεση Μόνο δύο προβλήματα υγείας Γίνετε ερευνητές υγείας Η ανακάλυψη Όλα έχουν μοναδική συχνότητα Επιλεκτική ηλεκτροπληξία Βιο-ακτινοβολία Εξοντώνοντας μαμούνια Το φάσμα της βιο-ακτινοβολίας Θεραπεία με ζάπερ Θανάτωση των παθογόνων που επιβιώνουν Σχέδιο και κατασκευή ζάπερ Προαιρετικές δράσεις...
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Cancer Informatics, Volume 18, Issue , January-December 2019. Background:Acute myeloid leukemia (AML) is an extremely heterogeneous malignant disorder; AML has been reported as one of the main causes of death in children. The objective of this work was to classify the most deleterious mutation in CCAAT/enhancer-binding protein-alpha (CEBPA) and to predict their influence on the functional, structural, and expression levels by various Bioinformatics analysis tools.Methods:The single nucleotide polymorphisms...
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Abstract Grooming in primates is often considered a “currency” that can be exchanged for other “services” or “commodities” such as reciprocal grooming, coalitionary support, infant handling, tolerance around food sources, active food sharing, or mating opportunities. Previous studies on primate grooming‐for‐sex exchange viewed the males as the demanding class, with the females as suppliers of mating opportunities. In this study, we examine the broader context of grooming‐for‐mating exchange in...
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Journal of International Medical Research, Ahead of Print.
Journal of International Medical Research, Ahead of Print.
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Nature, Published online: 20 August 2019; doi:10.1038/d41586-019-02467-xDeath rates from cardiovascular disease were falling in many wealthy nations but are now plateauing.
Nature, Published online: 20 August 2019; doi:10.1038/d41586-019-02463-1Skulls found in an ancient settlement in the Andes Mountains were altered for display.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02482-yAlkaline compound helps the tuberculosis bacterium to ward off an acid attack from host cells.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02479-7Some highly cited academics seem to be heavy self-promoters — but researchers warn against policing self-citation.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02484-wIf the country’s main science-funding agency doesn’t get more cash soon, young researchers will stop getting paid.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02499-3The newborn Universe, the first-ever ring of pure carbon and why we must eat less meat to save the world.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02489-5The region produces most of the world’s banana exports — and the fungus affects the most popular commercial variety.
Nature, Published online: 19 August 2019; doi:10.1038/s41586-019-1497-4Phase curve measurements for the small (1.3 Earth radii) terrestrial exoplanet LHS 3844b show absence of a thick atmosphere, in agreement with theoretical predictions.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02477-9Combining the data-analysis tool Starfish with technologies to pinpoint RNA’s cellular locations can add spatial detail to in situ transcriptomics.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02452-4The tip of a scanning tunnelling microscope has been used to convert a molecular assembly into a 2D polymer and back, at room temperature — revealing how extreme environmental conditions can alter the progress of reactions.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02485-9The agency will co-ordinate the country’s activities in space and develop technologies.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02476-wAnne Harrington finds that a chronicle of syphilis and hysteria blurs body and mind.
Nature, Published online: 19 August 2019; doi:10.1038/d41586-019-02490-yAlan Cooper, who leads of the Australian Centre for Ancient DNA, has been stood down pending an investigation.
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Chronic hepatitis B (CHB) infection poses a significant burden to public health worldwide. Most cases are clinically silent until late in the disease course. The main goal of current therapy is to improve surv...
A systematic review of experimental methods to manipulate secondary hyperalgesia in humans: protocol
Neuropathic pain affects 7–10% of people, but responds poorly to pharmacotherapy, indicating a need for better treatments. Mechanistic research on neuropathic pain frequently uses human surrogate models of the...
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An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Future Oncology, Volume 15, Issue 23, Page 2669-2671, August 2019.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
Future Oncology, Ahead of Print.
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The natural history of patients diagnosed with Eisenmenger’s Syndrome typically revolve around the pediatric population. Medical advances have allowed these patients to live longer and present with a different...
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Thyroid, Ahead of Print.
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Surgical Infections, Ahead of Print.
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Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
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Tumor targeting small molecular inhibitors are the most popular treatments for many malignant diseases, including cancer. However, the lower clinical response and drug resistance still limit their clinical eff...
In order to develop a new immunotherapeutic agent targeting metastatic breast cancers, we chose to utilize autocatalytic feature of the membrane serine protease Prss14/ST14, a specific prognosis marker for ER ...
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Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN00900K, PaperSeung Jun Oh, Tae Seok SeoWe present a centrifugal microfluidic device which is combined with a solution-loading cartridge for fully automatic molecular diagnostics of foodborne pathogens. The proposed device could perform the whole processes of...The content of this RSS Feed (c) The Royal Society of Chemistry
3h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01110B, PaperYingjie Wang, Hai Chen, Jiachen Zang, Xiuqing Zhang, Guanghua ZhaoProtein nanocages have recently received considerable attention in the field of nanoscience and nanomedicine, which have been used as either biotemplates for the preparation of a variety of nanomaterials or...The content of this RSS Feed (c) The Royal Society of Chemistry
15h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01270B, CommunicationRongrong Cao, Hong Huang, Jie Liang, Ting Wang, Yonglan Luo, Abdullah M. Asiri, Hejiang Ye, Xuping SunNitrite widely found in the environment and food industry poses a great threat to human health because of its potential toxicity, and its detection is of great importance. Therefore, we...The content of this RSS Feed (c) The Royal Society of Chemistry
16h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01078E, PaperRatish R Nair, M Raju, Surjit Bhai, Ishan Raval, Soumya Haldar, Bishwajit Ganguly, Pabitra Baran ChatterjeeIn order to explore the property of any species, actual concentration of the free species in solution should be taken into account rather than the added concentration of the analyte....The content of this RSS Feed (c) The Royal Society of Chemistry
17h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01121H, PaperLing Wu, Yuhan He, Yuqing Hu, Hanwen Lu, Zhong Cao, Xinyao Yi, Jianxiu WangPhosphorylation serves as important post-translational modification implicated in cellular signaling and regulation. In this work, real-time monitoring of site-specific phosphorylation of p53 protein by several protein kinases, followed by interaction...The content of this RSS Feed (c) The Royal Society of Chemistry
20h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01246J, CommunicationYuliya E. Silina, Daria Semenova, Boris A. SpiridonovHerein, we introduce an original strategy towards one-step encapsulation, storage and controlled release of small molecular weight organic compounds via electroplated nanoparticles. The concept is demonstrated on encapsulation of several...The content of this RSS Feed (c) The Royal Society of Chemistry
20h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01077G, PaperShuai Yue, Wenqi Ye, Zhangrun XuSurface enhanced-Raman scattering (SERS) spectroscopy as a powerful tool has been utilized to explore different catalysis degradation reactions, whereas some drawbacks caused by ferric ions still exist in the current...The content of this RSS Feed (c) The Royal Society of Chemistry
21h
Analyst, 2019, Accepted ManuscriptDOI: 10.1039/C9AN01325C, PaperZhiqiang Chen, Shuang Liu, Xiaoxiao Yu, Lijie Hao, Li Wang, Shufeng LiuAlkaline phosphatase (ALP) is an important enzyme related with many clinical diseases, and also widely used as a labeling enzyme for immunoassay. Herein, a new electrochemical sensing strategy for ALP...The content of this RSS Feed (c) The Royal Society of Chemistry
23h
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