Κυριακή 4 Αυγούστου 2019

The conventional protocol vs. a protocol including illumination with a fabric‐based biophotonic device (the Phosistos protocol) in photodynamic therapy for actinic keratosis: a randomized, controlled, noninferiority clinical study
S. Mordon, A.S. Vignion‐Dewalle, H. Abi‐Rached, E. Thecua, F. Lecomte, C. Vicentini, P. Deleporte, H. Béhal, D. Kerob, T. Hommel, A. Duhamel, R.M. Szeimies, L. Mortier
Version of Record online: 01 August 2019
What's already known about this topic?

  • Topical photodynamic therapy using methyl aminolaevulinate is effective for treating actinic keratosis.
  • In Europe, the conventional protocol involves illumination with a red‐light lamp. Unfortunately, pain is often experienced by patients undergoing this protocol.
  • An alternative protocol that uses daylight illumination has recently been shown to be as effective as the conventional protocol while being nearly painless. However, this alternative protocol can be conducted only in suitable weather conditions.

What does this study add?

  • The Phosistos protocol is demonstrated to be as effective as the conventional protocol, nearly as painless as the daylight protocols and suitable year round for treatment of actinic keratosis.

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