Σάββατο 17 Αυγούστου 2019


Voice Symptoms, Perceived Voice Control, and Common Mental Disorders in Elementary School Teachers.
Related ArticlesVoice Symptoms, Perceived Voice Control, and Common Mental Disorders in Elementary School Teachers. J Voice. 2019 Aug 12;: Authors: Barbosa IK, Behlau M, Lima-Silva MF, Almeida LN, Farias H, Almeida AA Abstract INTRODUCTION: Evaluating the relationship among teachers' voice symptoms, perceived voice control, and common mental disorders (CMDs) might contribute to the understanding of the relationship between vocal wear and the teacher...
Dysphonia
now
Exploring stimulation patterns for electrical stimulation of the larynx using surface electrodes.
Related ArticlesExploring stimulation patterns for electrical stimulation of the larynx using surface electrodes. Eur Arch Otorhinolaryngol. 2019 Aug 14;: Authors: Feiner M, Gerstenberger C, Mayr W, Hortobagyi D, Gugatschka M Abstract PURPOSE: Functional electrical stimulation (FES) is considered an upcoming treatment modality for a number of laryngeal diseases. However, sound data are scarce when it comes to surface FES to treat voice disorders. Aim...
Dysphonia
1d
Effects of transverse maxillomandibular distraction osteogenesis on obstructive sleep apnea syndrome and on the pharynx.
Related ArticlesEffects of transverse maxillomandibular distraction osteogenesis on obstructive sleep apnea syndrome and on the pharynx. Sleep Breath. 2019 Aug 15;: Authors: Vinha PP, Faria AC, Christino M, de Mello-Filho FV Abstract PURPOSE: To assess the effects of transverse maxillomandibular distraction osteogenesis (TMDO) on the treatment of obstructive sleep apnea (OSA) and on the morphology of the pharynx. METHODS: A clinical trial was...
pubmed: sleep apnea
2m
Hypoglossal nerve stimulation long-term clinical outcomes: a systematic review and meta-analysis.
Related ArticlesHypoglossal nerve stimulation long-term clinical outcomes: a systematic review and meta-analysis. Sleep Breath. 2019 Aug 15;: Authors: Costantino A, Rinaldi V, Moffa A, Luccarelli V, Bressi F, Cassano M, Casale M, Baptista P Abstract OBJECTIVE: To perform a systematic review and meta-analysis for studies evaluating hypoglossal nerve stimulation (HNS) clinical outcomes in the treatment of moderate to severe obstructive sleep apnea (OSA)....
pubmed: sleep apnea
2m
The physiological phenotype of obstructive sleep apnea differs between Caucasian and Chinese patients.
Related ArticlesThe physiological phenotype of obstructive sleep apnea differs between Caucasian and Chinese patients. Sleep. 2019 Aug 16;: Authors: O'Driscoll DM, Landry SA, Pham J, Young A, Sands SA, Hamilton GS, Edwards BA Abstract STUDY OBJECTIVES: The mechanisms responsible for the development of obstructive sleep apnea (phenotypic "traits") are known to differ between individuals and may differ across ethnicities. We aimed to examine whether loop...
pubmed: sleep apnea
2m
Insulin Resistance in Patients With Acromegaly.
Related ArticlesInsulin Resistance in Patients With Acromegaly. Front Endocrinol (Lausanne). 2019;10:509 Authors: Vila G, Jørgensen JOL, Luger A, Stalla GK Abstract Acromegaly is characterized by chronic overproduction of growth hormone (GH) that leads to insulin resistance, glucose intolerance and, ultimately, diabetes. The GH-induced sustained stimulation of lipolysis plays a major role not only in the development of insulin resistance and prediabetes/diabetes,...
pubmed: sleep apnea
2m
Relationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke.
Related ArticlesRelationship Between Sleep Apnea and Coronary Artery Calcium in Patients With Ischemic Stroke. Front Neurol. 2019;10:819 Authors: Cho KH, Lee DH, Kim KM, Choi YH, Nam HS, Heo JH, Heo K, Kim YD Abstract Study Objectives: Coronary artery disease is considered to be the major cause of death amongst patients with ischemic stroke. The coronary artery calcium (CAC) score is related not only to sleep-disordered breathing, but also with future...
pubmed: sleep apnea
2m
Prevalence of STOP BANG questionnaire and association with major cardiovascular events in hospitalized population: is it enough with currently used cardiovascular risk measurements?
Related ArticlesPrevalence of STOP BANG questionnaire and association with major cardiovascular events in hospitalized population: is it enough with currently used cardiovascular risk measurements? Sleep Med. 2019 Mar 13;: Authors: Labarca G, Valdivia G, Oñate A, Navarrete C, Araya J, Fernandez-Bussy I, Dreyse J, Jorquera J Abstract Cardiovascular risk (CR) is associated with obstructive sleep apnea hypopnea syndrome (OSAHS). This association enhances...
pubmed: sleep apnea
2m
The prevalence of obstructive sleep apnea in mild cognitive impairment: a systematic review.
Related ArticlesThe prevalence of obstructive sleep apnea in mild cognitive impairment: a systematic review. BMC Neurol. 2019 Aug 15;19(1):195 Authors: Mubashir T, Abrahamyan L, Niazi A, Piyasena D, Arif AA, Wong J, Osorio RS, Ryan CM, Chung F Abstract BACKGROUND: Previous studies have shown that obstructive sleep apnea (OSA) is associated with a higher risk of cognitive impairment or dementia in the elderly, leading to deleterious health effects and...
pubmed: sleep apnea
2m
Corneal Topographic, Anatomic, and Biomechanical Properties in Severe Obstructive Sleep Apnea-Hypopnea Syndrome.
Related ArticlesCorneal Topographic, Anatomic, and Biomechanical Properties in Severe Obstructive Sleep Apnea-Hypopnea Syndrome. Cornea. 2019 Aug 12;: Authors: Arriola-Villalobos P, Benito-Pascual B, Peraza-Nieves J, Perucho-González L, Sastre-Ibañez M, Dupré-Peláez MG, Asorey-García A, Fernández-Sánchez-Alarcos JM Abstract PURPOSE: To determine corneal topographic, anatomic, and biomechanical properties in patients newly diagnosed with severe obstructive...
pubmed: sleep apnea
23h
The serum YKL-40 level is a potential biomarker for OSAHS: a systematic review and meta-analysis.
Related ArticlesThe serum YKL-40 level is a potential biomarker for OSAHS: a systematic review and meta-analysis. Sleep Breath. 2019 Aug 14;: Authors: Zhang Y, Su X, Pan P, Hu C Abstract PURPOSE: Several studies have reported that serum YKL-40 level was elevated in patients with obstructive sleep apnea hypopnea syndrome (OSAHS). However, most of these studies had relatively small sample sizes and the results were inconsistent. Therefore, a meta-analysis...
pubmed: sleep apnea
23h
[Upper Airway Stimulation for obstructive sleep apnea-Can radiological position monitoring predict tongue motion one year after implantation? German version].
Related Articles[Upper Airway Stimulation for obstructive sleep apnea-Can radiological position monitoring predict tongue motion one year after implantation? German version]. HNO. 2019 Aug 14;: Authors: Steffen A, Wozny AS, König IR, Goltz JP, Wollenberg B, Hasselbacher K Abstract BACKGROUND: Tongue motion patterns (TMP) can influence the outcome of upper airway stimulation (UAS) in the treatment of obstructive sleep apnea (OSA). As a postoperative control...
pubmed: sleep apnea
23h
Different diagnostic criteria for periodic leg movements in patients with obstructive sleep apnea after continuous positive airway pressure titration.
Related ArticlesDifferent diagnostic criteria for periodic leg movements in patients with obstructive sleep apnea after continuous positive airway pressure titration. Neuropsychiatr Dis Treat. 2019;15:2129-2136 Authors: Huang CY, Yu CC Abstract Objective: Periodic leg movement in sleep (PLMS) is common among patients with obstructive sleep apnea (OSA). The PLMS frequency changes after continuous positive airway pressure (CPAP) titration. This study investigated...
pubmed: sleep apnea
23h
Respiratory arrest requiring resuscitation as a rare presentation of obstructive sleep apnoea and hypothyroidism.
Related ArticlesRespiratory arrest requiring resuscitation as a rare presentation of obstructive sleep apnoea and hypothyroidism. BMJ Case Rep. 2019 Aug 13;12(8): Authors: Chiang KY, Ma TSK, Ip MSM, Lui MMS Abstract A 79-year-old man, who had significant cardiovascular morbidities, presented with out-of-hospital respiratory arrest. He regained breathing after brief cardiopulmonary resuscitation by his paramedic son. After meticulous investigations, acute...
pubmed: sleep apnea
23h
Approach to Management of Cerebrospinal Fluid Rhinorrhea: Institutional Based Protocol
Abstract The role of otolaryngologist in the management of CSF rhinorrhea is expanding. It is prudent to evaluate all cases of CSF leak, understand the etiological causes and formalize a working approach to management of such cases to yield better outcome. A retrospective descriptive study of 39 cases of proven CSF rhinorrhea treated at a tertiary care center between January 2014 to August 2019. The data retrieved were analyzed for age, gender, weight, etiology, recurrence of the...
Otolaryngology Indian
2m
Nomogram Identifies Age as the Most Important Predictor of Overall Survival in Oral Cavity Squamous Cell Cancer After Primary Surgery
Abstract Our goal was to determine the most important predictors and construct a nomogram for overall survival (OS) in oral cavity squamous cell cancer (OCSCC) treated with primary surgery followed by observation, adjuvant radiation or chemoradiation. Multivariable analysis was performed using Cox Proportional Hazard model of 9258 OCSCC patients from Surveillance, Epidemiology and End Results Program (SEER) database treated with surgery from 2003 to 2009. Potential predictors of...
Otolaryngology Indian
1d
A Comparative Study Between Septal Quilting Sutures Without Nasal Packing and Only Nasal Packing Post-septal Correction
Abstract Septal correction is the commonest surgery by rhinologists worldwide. We aimed at studying the comfort level of the patient with standard postoperative nasal packing with Merocel and placing quilting sutures in septum leaving the nose unpacked in the postoperative period. We conducted the study in the tertiary care centre enrolling 82 patients in a quasi-randomised method of odd and even numbers placing them in the nasal packing group and the quilting group respectively....
Otolaryngology Indian
1d
Impaired visuospatial attention revealed by theta- and beta-band cortical activities in idiopathic REM sleep behavior disorder patients
Publication date: Available online 16 August 2019Source: Clinical NeurophysiologyAuthor(s): Seongjin Her, Kwang Su Cha, Jeong Woo Choi, Hyun Kim, Jung-Ick Byun, Jun-Sang Sunwoo, Tae-Joon Kim, Jung-Ah Lim, Ki-Young Jung, Kyung Hwan KimAbstractObjectivesIdiopathic REM sleep behavior disorder (iRBD) patients are susceptible to cognitive deficits, especially attention dysfunction. The objective of this study is to elucidate the neural mechanism of the dysfunction in attention known as ‘inhibition of...
Clinical Neurophysiology
3m
Diagnostic added value of electrical source imaging in presurgical evaluation of patients with epilepsy: A prospective study
Publication date: Available online 16 August 2019Source: Clinical NeurophysiologyAuthor(s): Mette Thrane Foged, Terje Martens, Lars H. Pinborg, Nizar Hamrouni, Minna Litman, Guido Rubboli, Anne-Mette Leffers, Philippe Ryvlin, Bo Jespersen, Olaf B. Paulson, Martin Fabricius, Sándor BeniczkyAbstractObjectiveTo investigate the diagnostic added value of electrical source imaging (ESI) in presurgical evaluation of patients with drug resistant focal epilepsy.MethodsEighty-two consecutive patients were...
Clinical Neurophysiology
3m
Improvement of motor conduction velocity in hereditary neuropathy of LAMA2-CMD <em>dy<sup>2J</sup>/dy<sup>2J</sup></em> mouse model by glatiramer acetate
Publication date: Available online 16 August 2019Source: Clinical NeurophysiologyAuthor(s): Malcolm Rabie, Nurit Yanay, Yakov Fellig, Jenya Konikov-Rozenman, Yoram NevoAbstractObjectiveGlatiramer acetate (GA), an agent modulating the immune system, has been shown to cause significantly improved mobility and hind limb muscle strength in the dy2J/dy2J mouse model for LAMA2-congenital muscular dystrophy (LAMA2-CMD). In view of these findings and the prominent peripheral nervous system involvement in...
Clinical Neurophysiology
3m
Detection of early motor involvement in diabetic polyneuropathy using a novel MUNE method – MScanFit MUNE
Publication date: Available online 16 August 2019Source: Clinical NeurophysiologyAuthor(s): A.G. Kristensen, H. Bostock, N.B. Finnerup, H. Andersen, T.S. Jensen, S. Gylfadottir, M. Itani, T. Krøigård, S. Sindrup, H. TankisiAbstractObjectiveDetection of motor involvement in diabetic polyneuropathy (DPN) by nerve conduction studies (NCS) does not occur until there is substantial loss of motor units, because collateral reinnervation maintains compound muscle action potential (CMAP) amplitude. Motor...
Clinical Neurophysiology
4m
F Wave Analyzer, a system for repeater F-waves detection: Application in patients with amyotrophic lateral sclerosis
Publication date: Available online 16 August 2019Source: Clinical NeurophysiologyAuthor(s): Dimitra Veltsista, Chris Papapavlou, Elisabeth ChroniAbstractObjectivesWe assessed the clinical usefulness of repeater F-waves (Freps) analysis in amyotrophic lateral sclerosis (ALS), using an automated computerized system (F Wave Analyzer).MethodsForty consecutive F-waves were recorded from the ulnar and peroneal nerve in 52 patients with ALS and 52 healthy control subjects. Data were imported into the F...
Clinical Neurophysiology
4m
P1-10-04. Mismatch negativity predicts remission and neurocognitive function in individuals at ultra-high risk for psychosis
Publication date: Available online 6 August 2019Source: Clinical NeurophysiologyAuthor(s): Mao Fujioka, Kenji Kirihara, Daisuke Koshiyama, Mariko Tada, Tatsuya Nagai, Kaori Usui, Shinsuke Koike, Motomu Suga, Tsuyoshi Araki, Kiyoto Kasai
Clinical Neurophysiology
4m
Plasma fibrin clot proteomics in healthy subjects: Relation to clot permeability and lysis time
Publication date: Available online 16 August 2019Source: Journal of ProteomicsAuthor(s): Michał Ząbczyk, Aneta Stachowicz, Joanna Natorska, Rafał Olszanecki, Jacek R. Wiśniewski, Anetta UndasAbstractBackgroundLittle is known about fibrin clot composition in relation to its structure and lysability. We investigated plasma clots protein composition and its associations with clot properties.MethodsWe studied 20 healthy subjects aged 31–49 years in whom plasma fibrin clot permeability (Ks) and clot lysis...
ScienceDirect Publication: Journal of Proteomics
11m
Stable prevalence of chronic back disorders across gender, age, residence, and physical activity in Canadian adults from 2007 to 2014.
Related ArticlesStable prevalence of chronic back disorders across gender, age, residence, and physical activity in Canadian adults from 2007 to 2014. BMC Public Health. 2019 Aug 15;19(1):1121 Authors: Angarita-Fonseca A, Trask C, Shah T, Bath B Abstract BACKGROUND: Chronic back disorders (CBD) are a global health problem and the leading cause of years lived with disability. The present study aims to examine overall and specific trends in CBD in the...
pubmed: "bmc public health"[...
13m
Predictors of loss to follow-up among children on long-term antiretroviral therapy in Zambia (2003-2015).
Related ArticlesPredictors of loss to follow-up among children on long-term antiretroviral therapy in Zambia (2003-2015). BMC Public Health. 2019 Aug 15;19(1):1120 Authors: Mutanga JN, Mutembo S, Ezeamama AE, Song X, Fubisha RC, Mutesu-Kapembwa K, Sialondwe D, Simuchembu B, Chinyonga J, Thuma PE, Whalen CC Abstract BACKGROUND: Retention in care is critical for children living with HIV taking antiretroviral therapy (ART). Loss to follow-up (LTFU) is high...
pubmed: "bmc public health"[...
13m
We still don't know that our children need vitamin D daily: a study of parents' understanding of vitamin D requirements in children aged 0-2 years.
Related ArticlesWe still don't know that our children need vitamin D daily: a study of parents' understanding of vitamin D requirements in children aged 0-2 years. BMC Public Health. 2019 Aug 15;19(1):1119 Authors: Day RE, Krishnarao R, Sahota P, Christian MS Abstract BACKGROUND: Vitamin D deficiency has been highlighted as a serious public health problem in the United Kingdom. One in four toddlers are not achieving the recommended intake for their healthy...
pubmed: "bmc public health"[...
13m
"BMC Public Health"[jour]; +20 new citations
20 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "BMC Public Health"[jour] These pubmed results were generated on 2019/08/16PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: "bmc public health"[...
23h
Design, synthesis, and anticancer activity of iridium(III) complex-peptide hybrids that contain hydrophobic acyl groups at the N-terminus of the peptide units.
Design, synthesis, and anticancer activity of iridium(III) complex-peptide hybrids that contain hydrophobic acyl groups at the N-terminus of the peptide units. J Inorg Biochem. 2019 Aug 03;199:110785 Authors: Naito K, Yokoi K, Balachandran C, Hisamatsu Y, Aoki S Abstract In previous work, we reported on that Ir complex-cationic peptide hybrids (IPHs) that contain three KKGG or KKKGG sequences (K: lysine, G: glycine) induce cell death in cancer cells...
pubmed: "j inorg biochem"[jo...
14m
Cation and peptide binding properties of CML7, a calmodulin-like protein from Arabidopsis thaliana.
Cation and peptide binding properties of CML7, a calmodulin-like protein from Arabidopsis thaliana. J Inorg Biochem. 2019 Aug 01;199:110796 Authors: Trande M, Pedretti M, Bonza MC, Di Matteo A, D'Onofrio M, Dominici P, Astegno A Abstract Plants contain a large family of so-called calmodulin-like proteins (CMLs) which differ from canonical calmodulin in that they show greater variability in sequence, length, and number of EF-hand domains. The presence...
pubmed: "j inorg biochem"[jo...
14m
Scientists who leave research to pursue other careers in science are still scientists.
Related ArticlesScientists who leave research to pursue other careers in science are still scientists. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Hanlon SM PMID: 31416920 [PubMed - as supplied by publisher]
pubmed: "proc natl acad sci ...
18m
Reply to Hanlon: Transitions in science careers.
Related ArticlesReply to Hanlon: Transitions in science careers. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Milojević S, Radicchi F, Walsh JP PMID: 31416919 [PubMed - as supplied by publisher]
pubmed: "proc natl acad sci ...
18m
Neural networks-based variationally enhanced sampling.
Related ArticlesNeural networks-based variationally enhanced sampling. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Bonati L, Zhang YY, Parrinello M Abstract Sampling complex free-energy surfaces is one of the main challenges of modern atomistic simulation methods. The presence of kinetic bottlenecks in such surfaces often renders a direct approach useless. A popular strategy is to identify a small number of key collective variables and to introduce...
pubmed: "proc natl acad sci ...
18m
Short-chain diamines are the physiological substrates of PACE family efflux pumps.
Related ArticlesShort-chain diamines are the physiological substrates of PACE family efflux pumps. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Hassan KA, Naidu V, Edgerton JR, Mettrick KA, Liu Q, Fahmy L, Li L, Jackson SM, Ahmad I, Sharples D, Henderson PJF, Paulsen IT Abstract Acinetobacter baumannii has rapidly emerged as a major cause of gram-negative hospital infections worldwide. A. baumannii encodes for the transport protein AceI, which confers...
pubmed: "proc natl acad sci ...
18m
Cell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction.
Related ArticlesCell phenotypic plasticity requires autophagic flux driven by YAP/TAZ mechanotransduction. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Totaro A, Zhuang Q, Panciera T, Battilana G, Azzolin L, Brumana G, Gandin A, Brusatin G, Cordenonsi M, Piccolo S Abstract Autophagy, besides ensuring energy metabolism and organelle renewal, is crucial for the biology of adult normal and cancer stem cells. However, it remains incompletely understood...
pubmed: "proc natl acad sci ...
18m
Structure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain.
Related ArticlesStructure and dynamics of G protein-coupled receptor-bound ghrelin reveal the critical role of the octanoyl chain. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Ferré G, Louet M, Saurel O, Delort B, Czaplicki G, M'Kadmi C, Damian M, Renault P, Cantel S, Gavara L, Demange P, Marie J, Fehrentz JA, Floquet N, Milon A, Banères JL Abstract Ghrelin plays a central role in controlling major biological processes. As for other G protein-coupled...
pubmed: "proc natl acad sci ...
18m
Nucleosome positions alone can be used to predict domains in yeast chromosomes.
Related ArticlesNucleosome positions alone can be used to predict domains in yeast chromosomes. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Wiese O, Marenduzzo D, Brackley CA Abstract We use molecular dynamics simulations based on publicly available micrococcal nuclease sequencing data for nucleosome positions to predict the 3D structure of chromatin in the yeast genome. Our main aim is to shed light on the mechanism underlying the formation of...
pubmed: "proc natl acad sci ...
18m
CPEB3 inhibits translation of mRNA targets by localizing them to P bodies.
Related ArticlesCPEB3 inhibits translation of mRNA targets by localizing them to P bodies. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Ford L, Ling E, Kandel ER, Fioriti L Abstract Protein synthesis is crucial for the maintenance of long-term memory-related synaptic plasticity. The cytoplasmic polyadenylation element-binding protein 3 (CPEB3) regulates the translation of several mRNAs important for long-term synaptic plasticity in the hippocampus....
pubmed: "proc natl acad sci ...
18m
Addressing cellular heterogeneity in tumor and circulation for refined prognostication.
Related ArticlesAddressing cellular heterogeneity in tumor and circulation for refined prognostication. Proc Natl Acad Sci U S A. 2019 Aug 15;: Authors: Lim SB, Yeo T, Lee WD, Bhagat AAS, Tan SJ, Tan DSW, Lim WT, Lim CT Abstract Despite pronounced genomic and transcriptomic heterogeneity in non-small-cell lung cancer (NSCLC) not only between tumors, but also within a tumor, validation of clinically relevant gene signatures for prognostication has relied...
pubmed: "proc natl acad sci ...
18m

Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects.
Related ArticlesHydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Feng B, Sosa RP, Mårtensson AKF, Jiang K, Tong A, Dorfman KD, Takahashi M, Lincoln P, Bustamante CJ, Westerlund F, Nordén B Abstract Hydrophobic base stacking is a major contributor to DNA double-helix stability. We report the discovery of specific unstacking effects in certain semihydrophobic...
pubmed: "proc natl acad sci ...
23h
A pathway linking translation stress to checkpoint kinase 2 signaling in Neurospora crassa.
Related ArticlesA pathway linking translation stress to checkpoint kinase 2 signaling in Neurospora crassa. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Diernfellner ACR, Lauinger L, Shostak A, Brunner M Abstract Checkpoint kinase 2 (CHK-2) is a key component of the DNA damage response (DDR). CHK-2 is activated by the PIP3-kinase-like kinases (PI3KKs) ataxia telangiectasia mutated (ATM) and ataxia telangiectasia and Rad3-related protein (ATR), and...
pubmed: "proc natl acad sci ...
23h
Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection.
Related ArticlesToxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Matta SK, Olias P, Huang Z, Wang Q, Park E, Yokoyama WM, Sibley LD Abstract In contrast to the importance of type II interferon-γ (IFN-γ) in control of toxoplasmosis, the role of type I IFN is less clear. We demonstrate here that TgIST, a secreted effector previously implicated in blocking type II...
pubmed: "proc natl acad sci ...
23h
Mitochondrial transcription factor A promotes DNA strand cleavage at abasic sites.
Related ArticlesMitochondrial transcription factor A promotes DNA strand cleavage at abasic sites. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Xu W, Boyd RM, Tree MO, Samkari F, Zhao L Abstract In higher eukaryotic cells, mitochondria are essential subcellular organelles for energy production, cell signaling, and the biosynthesis of biomolecules. The mitochondrial DNA (mtDNA) genome is indispensable for mitochondrial function because it encodes...
pubmed: "proc natl acad sci ...
23h
Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome.
Related ArticlesSingle-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Soares E, Xu Q, Li Q, Qu J, Zheng Y, Raeven HHM, Brandao KO, Petit I, van den Akker WMR, van Heeringen SJ, Aberdam D, Tang F, Zhou H Abstract Mutations in transcription factor p63 are associated with developmental disorders that manifest defects in stratified epithelia...
pubmed: "proc natl acad sci ...
23h
A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections.
Related ArticlesA dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Baral S, Antia R, Dixit NM Abstract Some viral infections culminate in very different outcomes in different individuals. They can be rapidly cleared in some, cause persistent infection in others, and cause mortality from immunopathology in yet others. The conventional...
pubmed: "proc natl acad sci ...
23h
Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis.
Related ArticlesDietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Matai L, Sarkar GC, Chamoli M, Malik Y, Kumar SS, Rautela U, Jana NR, Chakraborty K, Mukhopadhyay A Abstract Unfolded protein response (UPR) of the endoplasmic reticulum (UPRER) helps maintain proteostasis in the cell. The ability to mount an effective UPRER to external stress (iUPRER)...
pubmed: "proc natl acad sci ...
23h
Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling.
Related ArticlesArabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Rodríguez-Celma J, Connorton JM, Kruse I, Green RT, Franceschetti M, Chen YT, Cui Y, Ling HQ, Yeh KC, Balk J Abstract Organisms need to balance sufficient uptake of iron (Fe) with possible toxicity. In plant roots, a regulon of uptake genes is transcriptionally activated...
pubmed: "proc natl acad sci ...
23h
Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission.
Related ArticlesRole of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Singh P, Alaganan A, More KR, Lorthiois A, Thiberge S, Gorgette O, Guillotte Blisnick M, Guglielmini J, Aguilera SS, Touqui L, Singh S, Chitnis CE Abstract Transmission of Plasmodium falciparum involves a complex process that starts with the ingestion of gametocytes by female Anopheles...
pubmed: "proc natl acad sci ...
23h
Motility-limited aggregation of mammary epithelial cells into fractal-like clusters.
Related ArticlesMotility-limited aggregation of mammary epithelial cells into fractal-like clusters. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Leggett SE, Neronha ZJ, Bhaskar D, Sim JY, Perdikari TM, Wong IY Abstract Migratory cells transition between dispersed individuals and multicellular collectives during development, wound healing, and cancer. These transitions are associated with coordinated behaviors as well as arrested motility at high...
pubmed: "proc natl acad sci ...
23h
Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors.
Related ArticlesPiezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Zheng W, Nikolaev YA, Gracheva EO, Bagriantsev SN Abstract Tactile information is detected by thermoreceptors and mechanoreceptors in the skin and integrated by the central nervous system to produce the perception of somatosensation. Here we investigate the mechanism by which thermal and mechanical stimuli begin...
pubmed: "proc natl acad sci ...
23h
Regularizations of time crystal dynamics.
Related ArticlesRegularizations of time crystal dynamics. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Shapere AD, Wilczek F Abstract We demonstrate that nonconvex Lagrangians, as contemplated in the theory of time crystals, can arise in the effective description of conventional, physically realizable systems. Such embeddings resolve dynamical singularities which arise in the reduced description. Microstructure featuring intervals of fixed velocity...
pubmed: "proc natl acad sci ...
23h
Rickettsia conorii O antigen is the target of bactericidal Weil-Felix antibodies.
Related ArticlesRickettsia conorii O antigen is the target of bactericidal Weil-Felix antibodies. Proc Natl Acad Sci U S A. 2019 Aug 14;: Authors: Kim HK, Premaratna R, Missiakas DM, Schneewind O Abstract Rickettsial diseases have long been diagnosed with serum antibodies cross-reactive against Proteus vulgaris (Weil-Felix reaction). Although Weil-Felix antibodies are associated with the development of immunity, their rickettsial target and contribution...
pubmed: "proc natl acad sci ...
23h
An fMRI-study on single-sided deafness: Spectral-temporal properties and side of stimulation modulates hemispheric dominance.
An fMRI-study on single-sided deafness: Spectral-temporal properties and side of stimulation modulates hemispheric dominance. Neuroimage Clin. 2019 Aug 06;24:101969 Authors: Heggdal POL, Aarstad HJ, Brännström J, Vassbotn FS, Specht K Abstract OBJECTIVE: Our main aim was to investigate the blood oxygenation level dependent (BOLD) response to monaural and binaural speech- and non-speech stimuli as measured with fMRI in subjects with single-sided deafness...
Head and Neck
20m
Squamous cell carcinoma of the nasal cavity: A descriptive analysis of cases from the Head and Neck 5000 study.
Squamous cell carcinoma of the nasal cavity: A descriptive analysis of cases from the Head and Neck 5000 study. Clin Otolaryngol. 2019 Aug 16;: Authors: Dale OT, Pring M, Davies A, Leary S, Ingarfield K, Toms S, Waterboer T, Pawlita M, Ness AR, Thomas SJ Abstract OBJECTIVES: This paper aims to provide contemporary epidemiological data on squamous cell carcinoma (SCC) of the nasal cavity, which represents a rare type of head and neck cancer. ...
Head and Neck
20m
Clinical Applicability of a Preoperative Angular Insertion Depth Prediction Method for Cochlear Implantation.
Clinical Applicability of a Preoperative Angular Insertion Depth Prediction Method for Cochlear Implantation. Otol Neurotol. 2019 Sep;40(8):1011-1017 Authors: Rathgeb C, Demattè M, Yacoub A, Anschuetz L, Wagner F, Mantokoudis G, Caversaccio M, Wimmer W Abstract OBJECTIVE: Evaluation of the accuracy and clinical applicability of a single measure cochlear implant angular insertion depth prediction method. BACKGROUND: Cochlear implantation outcomes...
Head and Neck
20m
Plasma α-L-fucosidase-1 in patients with Sjögren's syndrome and other rheumatic disorders.
Plasma α-L-fucosidase-1 in patients with Sjögren's syndrome and other rheumatic disorders. Int J Rheum Dis. 2019 Aug 16;: Authors: Endreffy I, Bjørklund G, Bartha A, Chirumbolo S, Dadar M, Fényi Á Abstract BACKGROUND: Human α-fucosidase (EC 3.2.1.51) is a hydrolase the importance of which has been increasing in the latest years. However, data about its plasma level in children with autoimmune disorders, particularly Sjögren's syndrome (SS), are lacking....
Head and Neck
20m
Evaluation of weight loss in canine cancer bearing patients undergoing radiation therapy.
Evaluation of weight loss in canine cancer bearing patients undergoing radiation therapy. Vet Comp Oncol. 2019 Aug 16;: Authors: Callanan GF, Pfeiffer I, Smith K Abstract Critical weight loss, as defined by ≥5% decrease in body weight, has been associated with increased morbidity and mortality in human patients with cancers of the head and neck. Weight loss has anecdotally been reported to occur frequently in veterinary patients undergoing radiation...
Head and Neck
20m
Gender disparities are present in academic rank and leadership positions despite overall equivalence in research productivity indices among senior members of American Head and Neck Society (AHNS) Fellowship Faculty.
Gender disparities are present in academic rank and leadership positions despite overall equivalence in research productivity indices among senior members of American Head and Neck Society (AHNS) Fellowship Faculty. Head Neck. 2019 Aug 16;: Authors: Garstka ME, Randolph GW, Haddad AB, Nathan CO, Ibraheem K, Farag M, Deot N, Adib H, Hoof M, French K, Killackey MT, Kandil E Abstract BACKGROUND: This study aims to examine potential disparities in scholarly...
Head and Neck
20m
Is a voice-specific instrument more indicative of stroboscopy results than common clinical queries?
Is a voice-specific instrument more indicative of stroboscopy results than common clinical queries? Laryngoscope. 2019 Aug 16;: Authors: DeVore EK, Carroll TL, Shin JJ Abstract OBJECTIVES: To determine whether the Voice Handicap Index-10 (VHI-10) predicts diagnoses made via laryngoscopy/stroboscopy, as compared to common clinical inquiries about vocal characteristics. METHODS: We prospectively collected data from a cohort of 204 consecutive...
Head and Neck
20m

Anemia and blood transfusion requirements in endoscopic sinus surgery: A propensity-matched analysis.
Anemia and blood transfusion requirements in endoscopic sinus surgery: A propensity-matched analysis. Laryngoscope. 2019 Aug 16;: Authors: Povolotskiy R, Cerasiello SY, Siddiqui SH, Baredes S, Eloy JA, Hsueh WD Abstract OBJECTIVE: Massive bleeding requiring blood transfusion is a feared complication of endoscopic sinus surgery (ESS). In an effort to improve healthcare quality and outcomes, research is focused on identifying the risk factors for complications...
Head and Neck
20m
Frailty as a predictor of outcomes in patients undergoing head and neck cancer surgery.
Frailty as a predictor of outcomes in patients undergoing head and neck cancer surgery. Laryngoscope. 2019 Aug 16;: Authors: Goldstein DP, Sklar MC, de Almeida JR, Gilbert R, Gullane P, Irish J, Brown D, Higgins K, Enepekides D, Xu W, Su J, Alibhai SMH Abstract OBJECTIVES: To evaluate whether frailty and functional measures are predictors of perioperative complications and length of hospital stay (LOS) in patients undergoing head and neck cancer surgery....
Head and Neck
20m
Frontal inverted papillomas: A 25-year study.
Frontal inverted papillomas: A 25-year study. Laryngoscope. 2019 Aug 16;: Authors: Sham CL, van Hasselt CA, Chow SMW, Lee DLY, Cho RHW, Woo JKS, Tong MCF Abstract OBJECTIVES/HYPOTHESIS: This study analyzes the treatment outcomes of frontal inverted papillomas (FIPs) in an attempt to provide guidelines for surgery selection. STUDY DESIGN: Retrospective case series. METHODS: The treatment results of 29 FIPs classified into five categories...
Head and Neck
20m
Should an elective neck dissection be performed for maxillary sinus squamous cell carcinoma?
Should an elective neck dissection be performed for maxillary sinus squamous cell carcinoma? Laryngoscope. 2019 Aug 16;: Authors: Berger MH, Tajudeen BA, St John MA, Tjoa T, Kuan EC PMID: 31418862 [PubMed - as supplied by publisher]
Head and Neck
20m
Increased prevalence of vestibular loss in mild cognitive impairment and Alzheimer's disease.
Increased prevalence of vestibular loss in mild cognitive impairment and Alzheimer's disease. Curr Alzheimer Res. 2019 Aug 16;: Authors: Wei EX, Oh ES, Harun A, Ehrenburg M, Xue QL, Simonsick E, Agrawal Y Abstract BACKGROUND/AIMS: Recent evidence has shown that Alzheimer's disease (AD) patients have reduced vestibular function relative to healthy controls. In this study, we evaluated whether patients with mild cognitive impairment (MCI) also have reduced...
Head and Neck
20m
Effects of transverse maxillomandibular distraction osteogenesis on obstructive sleep apnea syndrome and on the pharynx.
Related ArticlesEffects of transverse maxillomandibular distraction osteogenesis on obstructive sleep apnea syndrome and on the pharynx. Sleep Breath. 2019 Aug 15;: Authors: Vinha PP, Faria AC, Christino M, de Mello-Filho FV Abstract PURPOSE: To assess the effects of transverse maxillomandibular distraction osteogenesis (TMDO) on the treatment of obstructive sleep apnea (OSA) and on the morphology of the pharynx. METHODS: A clinical trial was...
Head and Neck
20m
MAPKAPK2 (MK2) inhibition mediates radiation-induced inflammatory cytokine production and tumor growth in head and neck squamous cell carcinoma.
Related ArticlesMAPKAPK2 (MK2) inhibition mediates radiation-induced inflammatory cytokine production and tumor growth in head and neck squamous cell carcinoma. Oncogene. 2019 Aug 15;: Authors: Berggren KL, Restrepo Cruz S, Hixon MD, Cowan AT, Keysar SB, Craig S, James J, Barry M, Ozbun MA, Jimeno A, McCance DJ, Beswick EJ, Gan GN Abstract Radiation therapy (RT) is a cornerstone of treatment in the management of head and neck squamous cell carcinomas...
Head and Neck
20m
CXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression.
Related ArticlesCXCL14 suppresses human papillomavirus-associated head and neck cancer through antigen-specific CD8+ T-cell responses by upregulating MHC-I expression. Oncogene. 2019 Aug 15;: Authors: Westrich JA, Vermeer DW, Silva A, Bonney S, Berger JN, Cicchini L, Greer RO, Song JI, Raben D, Slansky JE, Lee JH, Spanos WC, Pyeon D Abstract Evasion of the host immune responses is critical for both persistent human papillomavirus (HPV) infection and...
Head and Neck
20m
The burdens of tuberculosis on patients with malignancy: incidence, mortality and relapse.
Related ArticlesThe burdens of tuberculosis on patients with malignancy: incidence, mortality and relapse. Sci Rep. 2019 Aug 15;9(1):11901 Authors: Shu CC, Liao KM, Chen YC, Wang JJ, Ho CH Abstract Population with malignancy is growing worldwide; however, its tuberculosis (TB) burden including remains unclear regarding incidence, mortality, and relapse. We retrieved information and identified patients with malignancy and TB between 2000 and 2015 from...
Head and Neck
20m
Effects of Humidification of the Vocal Tract and Respiratory Muscle Training in Women With Voice Symptoms-A Pilot Study.
Related ArticlesEffects of Humidification of the Vocal Tract and Respiratory Muscle Training in Women With Voice Symptoms-A Pilot Study. J Voice. 2019 Aug 12;: Authors: Huttunen K, Rantala L Abstract OBJECTIVE: The aim of this study was to determine the efficacy of a 4-week breathing exercise intervention in participants with voice symptoms. METHODS: Six nonsmoking women (mean age 49) experiencing voice symptoms used a novel device WellO2 for...
Head and Neck
20m
Donation to the university of bologna of the original gaspare tagliacozzi, "De curtorum chirurgia per insitionem".
Related ArticlesDonation to the university of bologna of the original gaspare tagliacozzi, "De curtorum chirurgia per insitionem". J Plast Reconstr Aesthet Surg. 2019 Aug 08;: Authors: Piccin O, Sgarzani R, Morselli PG PMID: 31416714 [PubMed - as supplied by publisher]
Head and Neck
20m
Potential role of autofluorescence imaging in determining biopsy of oral potentially malignant disorders: A large prospective diagnostic study.
Related ArticlesPotential role of autofluorescence imaging in determining biopsy of oral potentially malignant disorders: A large prospective diagnostic study. Oral Oncol. 2019 Aug 12;: Authors: Shi L, Li C, Shen X, Zhou Z, Liu W, Tang G Abstract Autofluorescence examination of oral tissues using the VELscope has been suggested as an adjunctive tool for cancer detection and diagnosis. This study aimed to determine the diagnostic value of VELscope in...
Head and Neck
20m
Choosing surgery or radiotherapy for oropharyngeal squamous cell carcinoma: is the issue definitely settled?
Related ArticlesChoosing surgery or radiotherapy for oropharyngeal squamous cell carcinoma: is the issue definitely settled? Lancet Oncol. 2019 Aug 12;: Authors: Grégoire V, Nicolai P PMID: 31416686 [PubMed - as supplied by publisher]
Head and Neck
20m
Radiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial.
Related ArticlesRadiotherapy versus transoral robotic surgery and neck dissection for oropharyngeal squamous cell carcinoma (ORATOR): an open-label, phase 2, randomised trial. Lancet Oncol. 2019 Aug 12;: Authors: Nichols AC, Theurer J, Prisman E, Read N, Berthelet E, Tran E, Fung K, de Almeida JR, Bayley A, Goldstein DP, Hier M, Sultanem K, Richardson K, Mlynarek A, Krishnan S, Le H, Yoo J, MacNeil SD, Winquist E, Hammond JA, Venkatesan V, Kuruvilla S, Warner A, Mitchell...
Head and Neck
20m
Dental implant and fungus ball in the ethmoid sinus.
Related ArticlesDental implant and fungus ball in the ethmoid sinus. Int J Oral Maxillofac Surg. 2019 Aug 13;: Authors: Lee DH, Yoon TM, Lee JK, Lim SC Abstract Dental migration into the ethmoid sinus is extremely rare. Furthermore, it is very unusual that a displaced dental implant is associated with a concomitant fungus ball in the ethmoid sinus. Herein, we report an unusual case of the coexistence of a dental implant and fungus ball in the ethmoid...
Head and Neck
20m
Identification and potential mechanisms of a 4-lncRNA signature that predicts prognosis in patients with laryngeal cancer.
Related ArticlesIdentification and potential mechanisms of a 4-lncRNA signature that predicts prognosis in patients with laryngeal cancer. Hum Genomics. 2019 Aug 15;13(1):36 Authors: Zhang G, Fan E, Zhong Q, Feng G, Shuai Y, Wu M, Chen Q, Gou X Abstract PURPOSE: This study aimed to describe the use of a novel 4-lncRNA signature to predict prognosis in patients with laryngeal cancer and to explore its possible mechanisms. METHODS: We identified...
Head and Neck
20m
Targeting Cellular Metabolism Modulates Head and Neck Oncogenesis.
Related ArticlesTargeting Cellular Metabolism Modulates Head and Neck Oncogenesis. Int J Mol Sci. 2019 Aug 14;20(16): Authors: Hsieh YT, Chen YF, Lin SC, Chang KW, Li WC Abstract Considering the great energy and biomass demand for cell survival, cancer cells exhibit unique metabolic signatures compared to normal cells. Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent neoplasms worldwide. Recent findings have shown that environmental...
Head and Neck
20m
Increased Incidence of Glaucoma in Sensorineural Hearing Loss: A Population-Based Cohort Study.
Related ArticlesIncreased Incidence of Glaucoma in Sensorineural Hearing Loss: A Population-Based Cohort Study. Int J Environ Res Public Health. 2019 Aug 14;16(16): Authors: Chien HW, Wu PH, Wang K, Sun CC, Huang JY, Yang SF, Chen HC, Lee CY Abstract The purpose of the current study was to evaluate the incidence of glaucoma in patients diagnosed with sensorineural hearing loss (SNHL) via the application of the National Health Insurance Research Database...
Head and Neck
20m

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου