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Related ArticlesEssential characterisation of human papillomavirus positive head and neck cancer cell lines. Oral Oncol. 2020 Feb 28;103:104613 Authors: Greaney-Davies FST, Risk JM, Robinson M, Liloglou T, Shaw RJ, Schache AG Abstract OBJECTIVES: The incidence of human papillomavirus (HPV)-positive head and neck cancer, particularly oropharyngeal, has been increasing rapidly. Understanding of this disease, and modelling of suitable therapeutics,...
Related ArticlesIncidence of pedicle ossification in osseous free flap reconstruction in the head and neck. Oral Oncol. 2020 Feb 28;103:104611 Authors: Wood CB, Rohde SL, Sinard RJ, Mannion K, Bigcas JM Abstract BACKGROUND: There are several reports of ossification occurring along the pedicle of fibular free flaps in head and neck microvascular reconstruction, but the incidence of pedicle ossification of other osseous flaps in head and neck surgery...
Related ArticlesShallow whole genome sequencing of adenoid cystic carcinomas of the salivary glands identifies specific chromosomal aberrations related to tumor progression. Oral Oncol. 2020 Feb 28;103:104615 Authors: Cordesmeyer R, Laskawi R, Schliephake H, Kauffmann P, Beck J, Bornemann-Kolatzki K, Schütz E, Ströbel P, Kueffer S, Fichtner A, Bremmer F Abstract BACKGROUND AND PURPOSE: Adenoid cystic carcinomas (ACC) are characterized by high rate...
Related ArticlesGlobal frequency and distribution of head and neck cancer in pediatrics, a systematic review. Crit Rev Oncol Hematol. 2020 Jan 30;148:102892 Authors: Arboleda LPA, de Mendonça RMH, Lopez EEM, Araújo ALD, Palmier NR, de Pauli Paglioni M, Fonseca JM, Hoffmann IL, Cardinalli IA, Chaves ALF, Aranda S, Brandão TB, Lopes MA, Ribeiro ACP, Troconis CCM, Santos-Silva AR Abstract BACKGROUND: Incidence and mortality rates of childhood cancer...
Related ArticlesCalcium signaling in interdental cells during the critical developmental period of the mouse cochlea. Hear Res. 2020 Feb 15;389:107913 Authors: Schade-Mann T, Münkner S, Eckrich T, Engel J Abstract The tectorial membrane (TM), a complex acellular structure that covers part of the organ of Corti and excites outer hair cells, is required for normal hearing. It consists of collagen fibrils and various glycoproteins, which are synthesized...
Related ArticlesIntraoperative intravenous ibuprofen use is not associated with increased post-tonsillectomy bleeding. Int J Pediatr Otorhinolaryngol. 2020 Feb 21;133:109965 Authors: Patel NK, Shah SJ, Lee NK, Gao Q, Carullo VP, Yang CJ Abstract OBJECTIVES: Intravenous (IV) ibuprofen was approved by the FDA for use in pediatric patients in November 2015. The objective of this study was to compare bleeding rates in pediatric tonsillectomy patients...
Related ArticlesHPV+ HNSCC-Derived Exosomal miR-9 Induces Macrophage M1 Polarization and Increases Tumor Radiosensitivity. Cancer Lett. 2020 Feb 28;: Authors: Tong F, Mao X, Zhang S, Xie H, Yan B, Wang B, Sun J, Wei L Abstract Human papillomavirus (HPV) is an etiological risk factor for a subset of head and neck squamous cell carcinoma (HNSCC). HPV+ HNSCC is more radiosensitive than HPV- HNSCC, however, the mechanism underlying this observation remains...
Related ArticlesCorrelation between histogram-based DCE-MRI parameters and 18F-FDG PET values in oropharyngeal squamous cell carcinoma: Evaluation in primary tumors and metastatic nodes. PLoS One. 2020;15(3):e0229611 Authors: Vidiri A, Gangemi E, Ruberto E, Pasqualoni R, Sciuto R, Sanguineti G, Farneti A, Benevolo M, Rollo F, Sperati F, Spasiano F, Pellini R, Marzi S Abstract OBJECTIVES: To investigate the correlation between histogram-based Dynamic...
Related ArticlesAlpha Test of Intelligent Machine Learning in Staging Head and Neck Cancer. J Clin Oncol. 2020 Mar 02;:JCO1903309 Authors: O'Sullivan B, Huang SH, de Almeida JR, Hope A PMID: 32119596 [PubMed - as supplied by publisher]
Related ArticlesAssessment of surgical tumor-free resection margins in fresh squamous-cell carcinoma resection specimens of the tongue using a clinical MRI system. Head Neck. 2020 Mar 02;: Authors: Heidkamp J, Weijs WLJ, van Engen-van Grunsven ACH, de Laak-de Vries I, Maas MC, Rovers MM, Fütterer JJ, Steens SCA, Takes RP Abstract BACKGROUND: Current intraoperative methods of visual inspection and tissue palpation by the surgeon, and frozen section...
Predicting Obstructive Sleep Apnea Status With the Reflux Symptom Index in a Sleep Study Population.
Related ArticlesPredicting Obstructive Sleep Apnea Status With the Reflux Symptom Index in a Sleep Study Population. Laryngoscope. 2020 Mar 02;: Authors: Teklu M, Gouveia CJ, Yalamanchili A, Ghadersohi S, Price CPE, Bove M, Attarian HP, Tan BK Abstract OBJECTIVES/HYPOTHESIS: Otolaryngologic symptoms of obstructive sleep apnea (OSA) and their diagnostic utility are not well studied. We aimed to elucidate the prevalence of otolaryngologic symptoms...
Related ArticlesNasolacrimal Lymphangioma Presenting With Hemolacria. Ophthalmic Plast Reconstr Surg. 2020 Feb 24;: Authors: Li E, Yoda RA, Keene CD, Moe KS, Chambers C, Zhang MM Abstract A 22-year-old male presented with spontaneous unilateral hemolacria and was found to have complete opacification of the ipsilateral nasolacrimal sac and duct. Endoscopic biopsy with histopathologic analysis revealed the diagnosis of nasolacrimal lymphangioma. Additional...
Related ArticlesHearing Preservation Outcomes and Prognostic Factors in Acoustic Neuroma Surgery: Predicting Cutoffs. Otol Neurotol. 2020 Feb 28;: Authors: Zanoletti E, Mazzoni A, Frigo AC, Borsetto D, Cazzador D Abstract OBJECTIVE: To investigate the outcomes of hearing preservation surgery (HPS) for acoustic neuroma and quantify tumor and patient characteristics predictive of hearing preservation after surgery. STUDY DESIGN: Retrospective...
Related ArticlesVideo Head Impulse Test Results in Patients With a Vestibular Schwannoma-Sensitivity and Correlation With Other Vestibular System Function Tests, Hearing Acuity, and Tumor Size. Otol Neurotol. 2020 Feb 28;: Authors: West N, Sass H, Klokker M, Cayé-Thomasen P Abstract OBJECTIVE: No previous studies have investigated a vestibular function test battery combining the Video Head Impulse Test (VHIT), the caloric test, and the cervical vestibular...
Related ArticlesIncreased risk of herpes zoster in patients with peptic ulcers: A longitudinal follow-up study using a national sample cohort. Medicine (Baltimore). 2020 Feb;99(9):e19318 Authors: Jin YJ, Park B, Park IS, Choi HG Abstract The purpose of this study was to investigate the association of herpes zoster infection with peptic ulcer disease in a Korean population.The Korean National Health Insurance Service selects samples directly from...
Related ArticlesPhysical symptoms and mental health status in deep underground miners: A cross-sectional study. Medicine (Baltimore). 2020 Feb;99(9):e19294 Authors: Xie H, Liu J, Gao M, Liu Y, Ma T, Lu Y, Li C, Wang M, Zhang R, Wu J, Zou J, Liu S, Li W Abstract The aim of the present study was to reveal the physical symptom changes and their correlations with mental health status in deep underground miners.A total of 286 deep underground miners completed...
Related ArticlesPercutaneous sclerotherapy with polidocanol under the guidance of ultrasound for venous malformations in children - A retrospective cohort study from a single tertiary medical center. Medicine (Baltimore). 2020 Feb;99(9):e18839 Authors: Hou F, Chen J, Xia M, Ding K, Zeng Q, Liu W Abstract This study reports our experience, the therapeutic outcomes and complications of percutaneous sclerotherapy (PS) with polidocanol to treat venous...
Related ArticlesEvaluation of Auricular Cartilage Reconstruction Using a 3-Dimensional Printed Biodegradable Scaffold and Autogenous Minced Auricular Cartilage. Ann Plast Surg. 2020 Feb 27;: Authors: Min SH, Kim JH, Lee MI, Kwak HH, Woo HM, Shim JH, Choi DM, Lee JS, Jeong JY, Kang BJ Abstract Auricular cartilage reconstruction represents one of the greatest challenges for otolaryngology-head and neck surgery. The native structure and composition...
Related ArticlesFactors affecting swallowing outcomes after total laryngectomy: Participant self-report using the swallowing outcomes after laryngectomy questionnaire. Head Neck. 2020 Mar 02;: Authors: Lee MT, Govender R, Roy PJ, Vaz F, Hilari K Abstract BACKGROUND: Little is known about what factors affect patient-reported swallowing outcome after total laryngectomy. We explored whether patient demographics, surgical variables, use of adjuvant treatment,...
Related ArticlesValidation of Gene Profiles for Analysis of Regional Lymphatic Metastases in Head and Neck Squamous Cell Carcinoma. Front Mol Biosci. 2020;7:3 Authors: Hu Z, Yang R, Li L, Mao L, Liu S, Qiao S, Ren G, Hu J Abstract The progress of Head and Neck Squamous Cell Carcinoma (HNSCC) is dependent on both cancer stem cells (CSCs) and immune suppression. This study was designed to evaluate the distribution of CSCs and the characteristic immune...
Related ArticlesWhen the Loss Costs Too Much: A Systematic Review and Meta-Analysis of Sarcopenia in Head and Neck Cancer. Front Oncol. 2019;9:1561 Authors: Hua X, Liu S, Liao JF, Wen W, Long ZQ, Lu ZJ, Guo L, Lin HX Abstract Purpose: Whether or not skeletal muscle mass (SMM) depletion, known as sarcopenia, has significant negative effects on the prognosis of patients with head and neck cancer (HNC) is both new and controversial. In this meta-analysis,...
Related ArticlesBest Practice in Surgical Treatment of Malignant Head and Neck Tumors. Front Oncol. 2020;10:140 Authors: Simon C, Nicolai P, Paderno A, Dietz A Abstract Purpose of review: Defining the best practice of surgical care for patients affected by malignant head and neck tumors is of great importance. In this review we aim to describe the evolution of "best practice" guidelines in the context of quality-of-care measures and discuss current...
Related ArticlesHeterozygous p53-R280T Mutation Enhances the Oncogenicity of NPC Cells Through Activating PI3K-Akt Signaling Pathway. Front Oncol. 2020;10:104 Authors: Qin ZQ, Li QG, Yi H, Lu SS, Huang W, Rong ZX, Tang YY, Xiao ZQ Abstract A heterozygous point mutation of p53 gene at codon 280 from AGA to ACA (R280T) frequently occurs in nasopharyngeal carcinoma (NPC) cell lines, and about 10% NPC tissues. However, the role of this mutation in the...
Related ArticlesSystemic Analysis of RNA Alternative Splicing Signals Related to the Prognosis for Head and Neck Squamous Cell Carcinoma. Front Oncol. 2020;10:87 Authors: Li Z, Chen X, Wei M, Liu G, Tian Y, Zhang X, Zhu G, Chen C, Liu J, Wang T, Lin G, Wang J, Cai G, Lv Y Abstract Alternative splicing (AS) is an important mechanism that is responsible for the production of protein diversity. An increasing body of evidence has suggested that out-of-control...
Related ArticlesLong-Term Patient-Reported Quality of Life After Stereotactic Body Radiation Therapy for Recurrent, Previously-Irradiated Head and Neck Cancer. Front Oncol. 2020;10:83 Authors: Thomas J, Wang H, Clump DA, Ferris RL, Duvvuri U, Ohr J, Heron DE Abstract Objectives: Long-term quality-of-life data following stereotactic body radiation therapy (SBRT) for recurrent head and neck cancer (rHNC) is underreported. We report patient-reported...
Related ArticlesCarbon Ion Therapy: A Modern Review of an Emerging Technology. Front Oncol. 2020;10:82 Authors: Malouff TD, Mahajan A, Krishnan S, Beltran C, Seneviratne DS, Trifiletti DM Abstract Radiation therapy is one of the most widely used therapies for malignancies. The therapeutic use of heavy ions, such as carbon, has gained significant interest due to advantageous physical and radiobiologic properties compared to photon based therapy. By...
Related ArticlesmiR-936 Suppresses Cell Proliferation, Invasion, and Drug Resistance of Laryngeal Squamous Cell Carcinoma and Targets GPR78. Front Oncol. 2020;10:60 Authors: Lin XJ, Liu H, Li P, Wang HF, Yang AK, Di JM, Jiang QW, Yang Y, Huang JR, Yuan ML, Xing ZH, Wei MN, Li Y, Shi Z, Ye J Abstract MicroRNAs (miRs) play important roles in tumor progression. miR-936 has been reported to suppress cell invasion and proliferation of glioma and non-small...
Related ArticlesIdentification and validation of key modules and hub genes associated with the pathological stage of oral squamous cell carcinoma by weighted gene co-expression network analysis. PeerJ. 2020;8:e8505 Authors: Hu X, Sun G, Shi Z, Ni H, Jiang S Abstract Background: Oral squamous cell carcinoma (OSCC) is a major lethal malignant cancer of the head and neck region, yet its molecular mechanisms of tumourigenesis are still unclear. ...
Related ArticlesIn Vitro Regeneration of Decellularized Pig Esophagus Using Human Amniotic Stem Cells. Biores Open Access. 2020;9(1):22-36 Authors: Nayakawde NB, Methe K, Banerjee D, Berg M, Premaratne GU, Olausson M Abstract Decellularization of esophagus was studied using three different protocols. The sodium deoxycholate/DNase-I (SDC/DNase-I) method was the most successful as evidenced by histology and DNA quantification of the acellular scaffolds....
Related ArticlesRobot-assisted excision of thyroglossal duct cyst by a postauricular facelift approach. Wideochir Inne Tech Maloinwazyjne. 2020 Mar;15(1):245-248 Authors: Lee DW, Tae K Abstract Introduction: A trend towards robotic scarless surgery using remote site incisions has developed in head and neck surgery for better cosmetic outcomes. We have carried out robot-assisted excision of thyroglossal duct cysts (TGDC) by a postauricular facelift...
Related ArticlesWGCNA Co-Expression Network Analysis Reveals ILF3-AS1 Functions as a CeRNA to Regulate PTBP1 Expression by Sponging miR-29a in Gastric Cancer. Front Genet. 2020;11:39 Authors: Ren ZH, Shang GP, Wu K, Hu CY, Ji T Abstract Gastric cancer (GC) is one of the most common types of human cancers worldwide. However, the detail mechanisms underlying GC progression remained to be investigated. The present study identified 2823 differently expressed...
Related ArticlesActivation of the Kynurenine Pathway in Human Malignancies Can Be Suppressed by the Cyclin-Dependent Kinase Inhibitor Dinaciclib. Front Immunol. 2020;11:55 Authors: Riess C, Schneider B, Kehnscherper H, Gesche J, Irmscher N, Shokraie F, Classen CF, Wirthgen E, Domanska G, Zimpfer A, Strüder D, Junghanss C, Maletzki C Abstract Indoleamine 2,3-dioxygenase (IDO) and tryptophan 2,3-dioxygenase (TDO2) are the key enzymes of tryptophan...
Related ArticlesTympanic Resonance Hypothesis. Front Neurol. 2020;11:14 Authors: Boedts MJO Abstract Seemingly unrelated symptoms in the head and neck region are eliminated when a patch is applied on specific locations on the Tympanic Membrane. Clinically, two distinct patient populations can be distinguished; cervical and masticatory muscle tensions are involved, and mental moods of anxiety or need. Clinical observations lead to the hypothesis of...
Related ArticlesPrediction of Vestibular Dysfunction by Applying Machine Learning Algorithms to Postural Instability. Front Neurol. 2020;11:7 Authors: Kamogashira T, Fujimoto C, Kinoshita M, Kikkawa Y, Yamasoba T, Iwasaki S Abstract Objective: To evaluate various machine learning algorithms in predicting peripheral vestibular dysfunction using the dataset of the center of pressure (COP) sway during foam posturography measured from patients with dizziness....
Related ArticlesIntracochlear Perfusion of Tumor Necrosis Factor-Alpha Induces Sensorineural Hearing Loss and Synaptic Degeneration in Guinea Pigs. Front Neurol. 2019;10:1353 Authors: Katsumi S, Sahin MI, Lewis RM, Iyer JS, Landegger LD, Stankovic KM Abstract Tumor necrosis factor-alpha (TNF-α) is a proinflammatory cytokine that plays a prominent role in the nervous system, mediating a range of physiologic and pathologic functions. In the auditory...
Related ArticlesCorrigendum: Genotype-Phenotype Association Analysis Reveals New Pathogenic Factors for Osteogenesis Imperfecta Disease. Front Pharmacol. 2019;10:1603 Authors: Shi J, Ren M, Jia J, Tang M, Guo Y, Ni X, Shi T Abstract [This corrects the article DOI: 10.3389/fphar.2019.01200.].PMID: 32116662 [PubMed - in process]
Related ArticlesBlebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells. Front Cell Neurosci. 2019;13:590 Authors: Gao S, Cheng C, Wang M, Jiang P, Zhang L, Wang Y, Wu H, Zeng X, Wang H, Gao X, Ma Y, Chai R Abstract Aging, noise, and ototoxic drug-induced hair cell (HC) loss are the major causes of sensorineural hearing loss. Aminoglycoside antibiotics are commonly used in the clinic, but these...
Related ArticlesPositive lymph node number and extranodal extension for predicting recurrence and survival in patients with salivary gland cancer. Head Neck. 2020 Mar 01;: Authors: Lee H, Roh JL, Cho KJ, Choi SH, Nam SY, Kim SY Abstract BACKGROUND: This study compared our proposed N classification including the addition of the number of positive lymph node (LN+) and extranodal extension (ENE) with the current and previous American Joint Committee...
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